n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide has been researched along with Lung Neoplasms in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atwell, GJ; Baguley, BC; Bos, CD; Denny, WA | 1 |
| Atwell, GJ; Baguley, BC; Denny, WA; Finlay, GJ; Gamage, SA; Spicer, JA | 1 |
| Baguley, BC; Marshall, E; Zhuang, L | 1 |
| Baguley, BC; Finlay, GJ; Haldane, A; Holdaway, KM | 1 |
| Baguley, BC; Bridewell, DJ; Finlay, GJ | 1 |
| Baguley, BC; Deady, LW; Denny, WA; Desneves, J; Finlay, GJ; Kaye, AJ; Thompson, M | 1 |
| Baguley, BC; Finlay, GJ; Gavin, JB; Haldane, A | 1 |
| Baguley, BC; Finlay, GJ | 1 |
8 other study(ies) available for n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide and Lung Neoplasms
| Article | Year |
|---|---|
Potential antitumor agents. 56. "Minimal" DNA-intercalating ligands as antitumor drugs: phenylquinoline-8-carboxamides.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; DNA; Intercalating Agents; Leukemia L1210; Leukemia P388; Ligands; Lung Neoplasms; Quinolines; Structure-Activity Relationship; Tumor Cells, Cultured | 1988 |
Structure-activity relationships for acridine-substituted analogues of the mixed topoisomerase I/II inhibitor N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
Topics: Acridines; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Enzyme Inhibitors; Leukemia; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Neoplasm Transplantation; Rats; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1997 |
Experimental solid tumour activity of N-[2-(dimethylamino)ethyl]-acridine-4-carboxamide.
Topics: Acridines; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Cell Line; Colonic Neoplasms; Humans; Intercalating Agents; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Nude; Regression Analysis; Time Factors; Transplantation, Heterologous | 1995 |
Cytokinetic differences in the action of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide as compared with that of amsacrine and doxorubicin.
Topics: Acridines; Adenocarcinoma; Amsacrine; Antineoplastic Agents; Cell Cycle; DNA, Neoplasm; Doxorubicin; Flow Cytometry; Lung Neoplasms; Tumor Cells, Cultured | 1993 |
Mechanism of cytotoxicity of N-[2-(dimethylamino)ethyl] acridine-4-carboxamide and of its 7-chloro derivative: the roles of topoisomerases I and II.
Topics: Acridines; Amsacrine; Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Survival; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Enzyme Inhibitors; Humans; Kinetics; Lung Neoplasms; Mice; Models, Chemical; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1999 |
Ring-substituted 11-oxo-11H-indeno[1,2-b]quinoline-6-carboxamides with similar patterns of cytotoxicity to the dual topo I/II inhibitor DACA.
Topics: Acridines; Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Jurkat Cells; Leukemia P388; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mice; Quinolines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1999 |
Unusual dynamics of killing of cultured Lewis lung cells by the DNA-intercalating antitumour agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
Topics: Acridines; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cell Death; Cell Survival; DNA, Neoplasm; Intercalating Agents; Kinetics; Lung Neoplasms; Time Factors; Tumor Cells, Cultured | 1992 |
Selectivity of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide towards Lewis lung carcinoma and human tumour cell lines in vitro.
Topics: Acridines; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Humans; Lung Neoplasms; Mice; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1989 |