n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide has been researched along with Leukemia P388 in 7 studies
*Leukemia P388: An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baguley, BC; Denny, WA; Rewcastle, GW | 1 |
| Atwell, GJ; Baguley, BC; Bos, CD; Denny, WA | 1 |
| Baguley, BC; Chen, Q; Deady, LW; Denny, WA | 1 |
| Atwell, GJ; Baguley, BC; Denny, WA; Finlay, GJ; Gamage, SA; Spicer, JA | 1 |
| Baguley, BC; Denny, WA; Finlay, GJ; Haldane, A; Hay, MP | 1 |
| Baguley, BC; Deady, LW; Denny, WA; Desneves, J; Finlay, GJ; Kaye, AJ; Thompson, M | 1 |
| Baguley, BC; Ching, LM; Darkin, SJ; Lawson, PA; Ralph, RK; Schneider, E | 1 |
7 other study(ies) available for n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide and Leukemia P388
| Article | Year |
|---|---|
Potential antitumor agents. 59. Structure-activity relationships for 2-phenylbenzimidazole-4-carboxamides, a new class of "minimal" DNA-intercalating agents which may not act via topoisomerase II.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Cell Survival; Chemical Phenomena; Chemistry, Physical; DNA; Intercalating Agents; Leukemia P388; Mice; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1990 |
Potential antitumor agents. 56. "Minimal" DNA-intercalating ligands as antitumor drugs: phenylquinoline-8-carboxamides.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; DNA; Intercalating Agents; Leukemia L1210; Leukemia P388; Ligands; Lung Neoplasms; Quinolines; Structure-Activity Relationship; Tumor Cells, Cultured | 1988 |
Electron-deficient DNA-intercalating agents as antitumor drugs: aza analogues of the experimental clinical agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
Topics: Acridines; Animals; Antineoplastic Agents; DNA; Intercalating Agents; Leukemia P388; Mice; Molecular Structure; Naphthyridines; Neoplasm Transplantation; Structure-Activity Relationship | 1994 |
Structure-activity relationships for acridine-substituted analogues of the mixed topoisomerase I/II inhibitor N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
Topics: Acridines; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Enzyme Inhibitors; Leukemia; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Neoplasm Transplantation; Rats; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1997 |
Cellular uptake of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA).
Topics: Acridines; Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Drug Resistance, Multiple; Enzyme Inhibitors; Intercalating Agents; Leukemia P388; Mice; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tritium; Tumor Cells, Cultured | 1999 |
Ring-substituted 11-oxo-11H-indeno[1,2-b]quinoline-6-carboxamides with similar patterns of cytotoxicity to the dual topo I/II inhibitor DACA.
Topics: Acridines; Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Jurkat Cells; Leukemia P388; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mice; Quinolines; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1999 |
Cell line selectivity and DNA breakage properties of the antitumour agent N-[2-(dimethylamino)ethyl]acridine-4-carboxamide: role of DNA topoisomerase II.
Topics: Acridines; Aminacrine; Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cell Survival; DNA Damage; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Neoplasm Proteins; Quinacrine; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1988 |