Compounds > n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide
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n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide and Colonic Neoplasms

n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide has been researched along with Colonic Neoplasms in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atwell, GJ; Baguley, BC; Denny, WA; Finlay, GJ; Gamage, SA; Spicer, JA2
Antonini, I; Cristalli, G; Dal Ben, D; Lambertucci, C; Volpini, R1
Baguley, BC; Marshall, E; Zhuang, L1
Baguley, BC; Denny, WA; Finlay, GJ; Graves, DE; Spicer, JA; Velea, L1

Other Studies

5 other study(ies) available for n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide and Colonic Neoplasms

ArticleYear
Structure-activity relationships for acridine-substituted analogues of the mixed topoisomerase I/II inhibitor N-[2-(dimethylamino)ethyl]acridine-4-carboxamide.
    Journal of medicinal chemistry, 1997, Jun-06, Volume: 40, Issue:12

    Topics: Acridines; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Enzyme Inhibitors; Leukemia; Leukemia P388; Lung Neoplasms; Mice; Molecular Structure; Neoplasm Transplantation; Rats; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1997
Structure-activity relationships for substituted bis(acridine-4-carboxamides): a new class of anticancer agents.
    Journal of medicinal chemistry, 1999, Jul-01, Volume: 42, Issue:13

    Topics: Acridines; Animals; Antineoplastic Agents; Colonic Neoplasms; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Mice; Mutation; Neoplasm Transplantation; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1999
Design, synthesis, and biological evaluation of new mitonafide derivatives as potential antitumor drugs.
    Bioorganic & medicinal chemistry, 2008, Sep-15, Volume: 16, Issue:18

    Topics: Antineoplastic Agents; Aza Compounds; Colonic Neoplasms; DNA; Drug Design; HT29 Cells; Humans; Inhibitory Concentration 50; Intercalating Agents; Isoquinolines; Naphthalimides; Structure-Activity Relationship; Tumor Cells, Cultured

2008
Experimental solid tumour activity of N-[2-(dimethylamino)ethyl]-acridine-4-carboxamide.
    Cancer chemotherapy and pharmacology, 1995, Volume: 36, Issue:3

    Topics: Acridines; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Cell Line; Colonic Neoplasms; Humans; Intercalating Agents; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Nude; Regression Analysis; Time Factors; Transplantation, Heterologous

1995
5,7-Disubstituted analogues of the mixed topoisomerase I/II poison N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA): DNA binding and patterns of cytotoxicity.
    Anti-cancer drug design, 1999, Volume: 14, Issue:1

    Topics: Acridines; Animals; Colonic Neoplasms; DNA, Neoplasm; Enzyme Inhibitors; Humans; Intercalating Agents; Magnetic Resonance Spectroscopy; Mice; Neoplasm Transplantation; Time Factors; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1999