n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide has been researched along with Cancer of Prostate in 1 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Chao, SW; Guh, JH; Hsu, JL; Huang, WJ; Li, TK; Liu, SP; Pan, SL; Yang, YC; Yu, CC | 1 |
1 other study(ies) available for n-(2'-(dimethylamino)ethyl)acridine-4-carboxamide and Cancer of Prostate
Article | Year |
---|---|
A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase I.
Topics: Acridines; Animals; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cells, Cultured; DNA Damage; DNA Repair; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Drugs, Investigational; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Male; Mice, Nude; Neoplasm Proteins; Prostate; Prostatic Neoplasms; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Burden; Vorinostat; Xenograft Model Antitumor Assays | 2014 |