n-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide has been researched along with Cell Transformation, Neoplastic in 2 studies
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Protein kinase inhibitors block v-Src- and v-Fps-induced 9E3 gene expression with the same dose-response curves seen for PKC agonist-induced 9E3 gene expression." | 1.28 | Evidence that v-src and v-fps gene products use a protein kinase C-mediated pathway to induce expression of a transformation-related gene. ( Berg, KL; Foster, DA; Joseph, C; Qureshi, SA; Spangler, R, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Trotta, RJ | 1 |
| Thomson, TM | 1 |
| Lacal, JC | 1 |
| Pellicer, A | 1 |
| Burstein, DE | 1 |
| Spangler, R | 1 |
| Joseph, C | 1 |
| Qureshi, SA | 1 |
| Berg, KL | 1 |
| Foster, DA | 1 |
2 other studies available for n-(2-(methylamino)ethyl)-5-isoquinolinesulfonamide and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Potentiation of oncogenic N-ras-induced neurite outgrowth and ornithine decarboxylase activity by phorbol dibutyrate and protein kinase inhibitor H-8.
Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Colforsin; Dexamethasone; Epidermal | 1990 |
Evidence that v-src and v-fps gene products use a protein kinase C-mediated pathway to induce expression of a transformation-related gene.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucl | 1989 |