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n-(2-(diethylamino)ethyl)-4-iodobenzamide and Melanoma

n-(2-(diethylamino)ethyl)-4-iodobenzamide has been researched along with Melanoma in 15 studies

*Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445) [MeSH]

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (66.67)18.2507
2000's5 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eisenhut, M; Gorgas, K; Haberkorn, U; Hull, WE; Just, W; Lay, D; Lehmann, WD; Mier, W; Mohammed, A1
Bacin, F; Bonafous, J; Chossat, F; D'Incan, M; Kemeny, JL; Mestas, D; Moins, N; Sillaire-Houtmann, I; Veyre, A1
Chéhadé, F; de Labriolle-Vaylet, C; Galle, P; Hindié, E; Labarre, P; Moins, N; Moreau, MF; Papon, J; Veyre, A1
Barety, M; Bonafous, JF; Bussière, F; Darcourt, J; Lacour, JP; Michelot, JM; Migneco, O; Rodot, S; Schneider, M; Thyss, A1
Bacin, FJ; Bonafous, JF; Bussiere, F; Chossat, FM; Madelmont, JC; Mauclaire, LP; Michelot, JM; Moreau, MF; Souteyrand, PA; Veyre, AJ1
Jeong, JM; John, CS; Kinuya, S; Le, N; McAfee, JG; Paik, CH; Reba, RC; Saga, T; Varma, VM1
Bartenstein, P; Brandau, W; Kamanabrou, D; Kirchner, B; Schober, O; Sciuk, J1
Bayle, M; Boire, JY; Labarre, P; Madelmont, JC; Michelot, J; Moins, N; Moreau, MF; Papon, J; Parry, D; Seguin, H1
Bossuyt, A; Everaert, H; Flamen, P; Franken, PR; Mertens, J1
Bossuyt, A; Everaert, H; Hennekes, R; Lodewijks, H1
Bacin, F; Bekhechi, D; Bonafous, J; Chossat, F; Kemeny, JL; Michelot, J; Moreau, MF; Veyre, A1
Brandau, W; Coenen, HH; Dittmann, H; Dutschka, K; Streffer, C; Zölzer, F1
Chehade, F; De Labriolle-Vaylet, C; Escaig, F; Galle, P; Hindié, E; Michelot, J; Moins, N; Moreau, MF; Papon, J; Veyre, A1
Bayle, M; Labarre, P; Madelmont, JC; Moins, N; Moreau, MF; Papon, J; Veyre, A1
Meyniel, G; Michelot, J; Moreau, MF; Veyre, A1

Trials

4 trial(s) available for n-(2-(diethylamino)ethyl)-4-iodobenzamide and Melanoma

ArticleYear
[Phase 2 clinical study of 123I-N-(2-diethylaminoethyl)-2-iodobenzamide in the diagnostic of primary and metastatic ocular melanoma].
    Journal francais d'ophtalmologie, 2004, Volume: 27, Issue:1

    Topics: Benzamides; Choroid Neoplasms; Ciliary Body; Conjunctival Neoplasms; Diagnosis, Differential; Eye Neoplasms; Female; Humans; Iodine Radioisotopes; Liver Neoplasms; Male; Melanoma; Ophthalmoscopy; Predictive Value of Tests; Radionuclide Imaging; Radiopharmaceuticals; Sensitivity and Specificity; Skin Neoplasms; Tomography, X-Ray Computed; Ultrasonography; Uveal Neoplasms

2004
A radiolabelled iodobenzamide for malignant melanoma staging.
    Melanoma research, 1994, Volume: 4, Issue:5

    Topics: Aged; Aged, 80 and over; Benzamides; Chemotherapy, Adjuvant; Choroid Neoplasms; Combined Modality Therapy; False Negative Reactions; False Positive Reactions; Female; Humans; Iodine Radioisotopes; Liver Neoplasms; Lung Neoplasms; Lymphatic Metastasis; Male; Melanoma; Neoplasm Staging; Neoplasms, Unknown Primary; Radionuclide Imaging; Remission Induction; Skin Neoplasms

1994
Phase II scintigraphic clinical trial of malignant melanoma and metastases with iodine-123-N-(2-diethylaminoethyl 4-iodobenzamide).
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1993, Volume: 34, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzamides; Female; Humans; Iodine Radioisotopes; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Radionuclide Imaging; Sensitivity and Specificity

1993
Clinical study of [123I] N-(2-diethylaminoethyl)-4-iodobenzamide in the diagnosis of primary and metastatic ocular melanoma.
    Acta ophthalmologica Scandinavica, 1998, Volume: 76, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Benzamides; Brachytherapy; Conjunctival Neoplasms; Contrast Media; Eye Enucleation; Female; Humans; Laser Coagulation; Liver Neoplasms; Lung Neoplasms; Male; Melanoma; Middle Aged; Radionuclide Imaging; Sensitivity and Specificity; Uveal Neoplasms

1998

Other Studies

11 other study(ies) available for n-(2-(diethylamino)ethyl)-4-iodobenzamide and Melanoma

ArticleYear
Radioiodinated N-(2-diethylaminoethyl)benzamide derivatives with high melanoma uptake: structure-affinity relationships, metabolic fate, and intracellular localization.
    Journal of medicinal chemistry, 2000, Oct-19, Volume: 43, Issue:21

    Topics: Animals; Benzamides; Brain; Centrifugation, Density Gradient; Chromatography, High Pressure Liquid; Contrast Media; Guinea Pigs; In Vitro Techniques; Iodine Radioisotopes; Iodobenzenes; Liver; Mass Spectrometry; Melanins; Melanoma; Mice; Mice, Inbred C57BL; Rats; Receptors, sigma; Structure-Activity Relationship; Tumor Cells, Cultured

2000
Secondary ion mass spectrometry as a tool for investigating radiopharmaceutical distribution at the cellular level: the example of I-BZA and (14)C-I-BZA.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005, Volume: 46, Issue:10

    Topics: Animals; Benzamides; Carbon Radioisotopes; Male; Melanoma; Mice; Mice, Inbred C57BL; Organ Specificity; Radionuclide Imaging; Radiopharmaceuticals; Spectrometry, Mass, Secondary Ion; Tissue Distribution

2005
An improved synthesis of [125I]N-(diethylaminoethyl)-4-iodobenzamide: a potential ligand for imaging malignant melanoma.
    Nuclear medicine and biology, 1993, Volume: 20, Issue:1

    Topics: Animals; Benzamides; Contrast Media; Humans; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Radionuclide Imaging; Tissue Distribution; Tumor Cells, Cultured

1993
N-(2-diethylaminoethyl)-4-[123I]iodobenzamide as a tracer for the detection of malignant melanoma: simple synthesis, improved labelling technique and first clinical results.
    European journal of nuclear medicine, 1993, Volume: 20, Issue:3

    Topics: Aged; Benzamides; Chromatography, High Pressure Liquid; Contrast Media; Female; Humans; Iodine Radioisotopes; Isotope Labeling; Male; Melanoma; Middle Aged; Radioimmunodetection; Skin Neoplasms; Technetium Tc 99m Pentetate

1993
Synthesis, radiolabeling, and preliminary evaluation in mice of some (N-diethylaminoethyl)-4-iodobenzamide derivatives as melanoma imaging agents.
    Nuclear medicine and biology, 1995, Volume: 22, Issue:6

    Topics: Animals; Benzamides; Humans; Indicators and Reagents; Iodine Radioisotopes; Isotope Labeling; Magnetic Resonance Spectroscopy; Male; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Radionuclide Imaging; Tissue Distribution

1995
Visualizing ocular melanoma using iodine-123-N-(2-diethylaminoethyl)4-iodobenzamide SPECT.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:6

    Topics: Benzamides; Diagnosis, Differential; Female; Humans; Iodine Radioisotopes; Male; Melanoma; Middle Aged; Nevus; Sensitivity and Specificity; Tomography, Emission-Computed, Single-Photon; Uveal Neoplasms

1997
I-123-IDAB: a new tracer for scintigraphic visualisation of malignant melanoma.
    Bulletin de la Societe belge d'ophtalmologie, 1996, Volume: 263

    Topics: Aged; Benzamides; Choroid Neoplasms; Contrast Media; Female; Humans; Iris Neoplasms; Male; Melanoma; Middle Aged; Neoplasm Invasiveness; Radionuclide Imaging

1996
In vitro studies on the cellular uptake of melanoma imaging aminoalkyl-iodobenzamide derivatives (ABA).
    Nuclear medicine and biology, 1999, Volume: 26, Issue:1

    Topics: Benzamides; Iodine Radioisotopes; Iodobenzoates; Melanins; Melanoma; Models, Biological; Radionuclide Imaging; Radiopharmaceuticals; Receptors, sigma; Sensitivity and Specificity; Structure-Activity Relationship; Tumor Cells, Cultured

1999
Distribution of I-BZA (N-2-diethylaminoethyl-4-iodobenzamide) in grafted melanoma and normal skin: a study by secondary ion mass spectroscopy.
    Cellular and molecular biology (Noisy-le-Grand, France), 2001, Volume: 47, Issue:3

    Topics: Animals; Benzamides; Lung Neoplasms; Male; Melanins; Melanoma; Mice; Neoplasm Transplantation; Organ Specificity; Skin; Spectrometry, Mass, Secondary Ion; Tumor Cells, Cultured

2001
Melanin affinity of N-(2-diethylaminoethyl)-4-iodobenzamide, an effective melanoma imaging agent.
    Melanoma research, 2002, Volume: 12, Issue:2

    Topics: Benzamides; Binding Sites; Cells, Cultured; Humans; Iodine Radioisotopes; Melanins; Melanoma; Skin Neoplasms; Tumor Cells, Cultured

2002
[Perspectives of scintigraphic diagnosis of malignant lymphoma using a new radiopharmaceutical].
    Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie, 1990, Volume: 311, Issue:1

    Topics: Animals; Benzamides; Contrast Media; Melanoma; Methods; Mice; Mice, Inbred C57BL; Mice, Nude; Radionuclide Imaging

1990