Compounds > n-((1-allyl-2-pyrrolidinyl)methyl)-5-(3-fluoropropyl)-2-3-dimethoxybenzamide

n-((1-allyl-2-pyrrolidinyl)methyl)-5-(3-fluoropropyl)-2-3-dimethoxybenzamide and Tourette-Syndrome

n-((1-allyl-2-pyrrolidinyl)methyl)-5-(3-fluoropropyl)-2-3-dimethoxybenzamide has been researched along with Tourette-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for n-((1-allyl-2-pyrrolidinyl)methyl)-5-(3-fluoropropyl)-2-3-dimethoxybenzamide and Tourette-Syndrome

Article	Year
Altered mesolimbocortical and thalamic dopamine in Tourette syndrome. Neurology, 2006, Nov-14, Volume: 67, Issue:9 We used [F-18]fallypride PET in six adults with Tourette syndrome and age-matched controls to assess extrastriatal dopamine 2 (D2) receptors. D2 receptor availability was significantly lower in the orbitofrontal cortex, primary motor cortex, anterior cingulate gyrus, mediodorsal nucleus of thalamus, and hippocampus, areas important for motivation and reward, sensory gating, movement, and attention. Altered dopaminergic function in mesolimbocortical systems and thalamus may contribute to increased motivational salience of tics. Topics: Adolescent; Adult; Benzamides; Brain; Cerebral Cortex; Dopamine; Down-Regulation; Humans; Limbic System; Magnetic Resonance Imaging; Male; Mesencephalon; Middle Aged; Neural Pathways; Positron-Emission Tomography; Pyrrolidines; Receptors, Dopamine D2; Reference Values; Synaptic Transmission; Thalamus; Tourette Syndrome	2006

Article

Year

Altered mesolimbocortical and thalamic dopamine in Tourette syndrome.

Neurology, 2006, Nov-14, Volume: 67, Issue:9

We used [F-18]fallypride PET in six adults with Tourette syndrome and age-matched controls to assess extrastriatal dopamine 2 (D2) receptors. D2 receptor availability was significantly lower in the orbitofrontal cortex, primary motor cortex, anterior cingulate gyrus, mediodorsal nucleus of thalamus, and hippocampus, areas important for motivation and reward, sensory gating, movement, and attention. Altered dopaminergic function in mesolimbocortical systems and thalamus may contribute to increased motivational salience of tics.

Topics: Adolescent; Adult; Benzamides; Brain; Cerebral Cortex; Dopamine; Down-Regulation; Humans; Limbic System; Magnetic Resonance Imaging; Male; Mesencephalon; Middle Aged; Neural Pathways; Positron-Emission Tomography; Pyrrolidines; Receptors, Dopamine D2; Reference Values; Synaptic Transmission; Thalamus; Tourette Syndrome

2006