n(g),n(g')-dimethyl-l-arginine has been researched along with Sleep Apnea Syndromes in 2 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
Sleep Apnea Syndromes: Disorders characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep. Sleep apnea syndromes are divided into central (see SLEEP APNEA, CENTRAL), obstructive (see SLEEP APNEA, OBSTRUCTIVE), and mixed central-obstructive types.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barceló, A | 1 |
| Piérola, J | 1 |
| de la Peña, M | 1 |
| Esquinas, C | 1 |
| Sanchez-de la Torre, M | 1 |
| Ayllón, O | 1 |
| Alonso, A | 1 |
| Agusti, AG | 1 |
| Barbè, F | 1 |
| Zoccali, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prevalence of Obstructive Sleep Apnea Syndrome and CPAP Adherence in the Elderly Chinese Population[NCT02085720] | 819 participants (Actual) | Interventional | 2007-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Elderly subjects who agree for home CPAP treatment are prescribed nasal CPAP units with time clocks to assess objective compliance (run time). (NCT02085720)
Timeframe: 1 year
| Intervention | hours (Mean) |
|---|---|
| Chinese Elderly OSAS | 4.2 |
Subjects who have completed the questionnaires and consented for sleep study are invited to undergo a portable at-home sleep study (EMBLETTA). It is a multi-channel screening tool that measures airflow through a nasal cannula connected to a pressure transducer, providing an apnea hypopnea index (AHI) based on recording time. AHI is the average number of events per hour while 5-15 events per hour denotes mild OSA, 16-30 events moderate OSA, and >30 events severe OSA. Obstructive sleep apnea syndrome is defined as AHI 15 events or above or AHI being 5 or above pulus ESS 10 or more. This measure is reporting the percentage of participants with OSAS. (NCT02085720)
Timeframe: 3 years
| Intervention | % of participants (Number) |
|---|---|
| Chinese Elderly OSAS | 15 |
RLS is a disorder characterized by disagreeable leg sensations that usually occur before sleep onset, causing an almost irresistible urge to move the legs. As minimal criteria for diagnosis, the following four features were required: (1) desire to move the extremities, often associated with paresthesias and/or dysesthesias; (2) motor restlessness; (3) worsening of symptoms at rest, with at least temporary relief by activity; and (4) worsening of symptoms in the evening or at night. (NCT02085720)
Timeframe: 3 years
| Intervention | % of participants (Number) |
|---|---|
| Chinese Elderly OSAS | 13.8 |
(NCT02085720)
Timeframe: 1 year
| Intervention | % of participants (Number) | |||
|---|---|---|---|---|
| AHI >/5 | AHI >/10 | AHI >/15 | AHI >/20 | |
| AHI Result | 66.7 | 43.6 | 29.9 | 19.2 |
(NCT02085720)
Timeframe: 1 year
| Intervention | % of participants (Number) | |||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Impaired performance ability (mild) | Impaired performance ability (moderate) | Impaired performance ability | Sleepiness interfered with daily tasks (mild) | Sleepiness interfered with daily tasks (moderate) | Sleepiness interfered with daily tasks(severe) | Impaired energy level (mild) | Impaired energy level (moderate) | Impaired energy level (severe) | Daytime sleepiness (mild) | Daytime sleepiness (moderate) | Daytime sleepiness (severe) | Snoring intensity (past month) (mild) | Snoring intensity (past month) (moderate) | Snoring intensity (past month) (severe) | Frequent awakenings (mild) | Frequent awakenings (moderate) | Frequent awakenings (severe) | Difficulty falling asleep (mild) | Difficulty falling asleep (moderate) | Difficulty falling asleep (severe) | observed awakenings (mild) | observed awakenings (moderate) | observed awakenings (severe) | observed choking (mild) | observed choking (moderate) | observed choking (severe) | Observed apnea (mild) | Observed apnea (moderate) | Observed apnea (severe) | |
| Sleep Heatlh Questionnaire Result | 41.5 | 8.5 | 8.7 | 10.2 | 3.4 | 3.8 | 39.2 | 8.0 | 9.4 | 41.1 | 8.5 | 22.8 | 33.0 | 8.2 | 5.1 | 38.3 | 8.6 | 19.3 | 48.4 | 7.8 | 9.9 | 6.6 | 0.7 | 0.8 | 2.8 | 1.1 | 0.7 | 1.7 | 0.4 | 0.6 |
1 review available for n(g),n(g')-dimethyl-l-arginine and Sleep Apnea Syndromes
| Article | Year |
|---|---|
[Cardiovascular events in chronic advanced renal insufficiency. Current concepts].
Topics: Anemia; Arginine; C-Reactive Protein; Cardiovascular Diseases; Humans; Hyperhomocysteinemia; Hyperli | 2003 |
1 other study available for n(g),n(g')-dimethyl-l-arginine and Sleep Apnea Syndromes
| Article | Year |
|---|---|
Day-night variations in endothelial dysfunction markers and haemostatic factors in sleep apnoea.
Topics: Adult; Arginine; Blood Coagulation; Body Mass Index; Cardiovascular Diseases; CD40 Ligand; Circadian | 2012 |