n(g),n(g')-dimethyl-l-arginine has been researched along with Renal Insufficiency in 22 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Plasma concentrations of the nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) increase already in the early stages of renal insufficiency." | 7.78 | Reduced renal plasma clearance does not explain increased plasma asymmetric dimethylarginine in hypertensive subjects with mild to moderate renal insufficiency. ( Bakker, JA; Bierau, J; De Leeuw, PW; Houben, AJ; Kroon, AA; Ronden, RA; Stehouwer, CD; Teerlink, T, 2012) |
| "In patients with cirrhosis, nitric oxide (NO), asymmetric dimethylarginine (ADMA), and possibly symmetric dimethylarginine (SDMA) have been linked to the severity of the disease." | 7.73 | Accumulation of symmetric dimethylarginine in hepatorenal syndrome. ( Del Olmo, JA; Lluch, P; Mauricio, MD; Medina, P; Rodrigo, JM; Segarra, G; Serra, MA; Vila, JM, 2006) |
| "Plasma concentrations of the nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) increase already in the early stages of renal insufficiency." | 3.78 | Reduced renal plasma clearance does not explain increased plasma asymmetric dimethylarginine in hypertensive subjects with mild to moderate renal insufficiency. ( Bakker, JA; Bierau, J; De Leeuw, PW; Houben, AJ; Kroon, AA; Ronden, RA; Stehouwer, CD; Teerlink, T, 2012) |
| "In patients with cirrhosis, nitric oxide (NO), asymmetric dimethylarginine (ADMA), and possibly symmetric dimethylarginine (SDMA) have been linked to the severity of the disease." | 3.73 | Accumulation of symmetric dimethylarginine in hepatorenal syndrome. ( Del Olmo, JA; Lluch, P; Mauricio, MD; Medina, P; Rodrigo, JM; Segarra, G; Serra, MA; Vila, JM, 2006) |
| "While renal failure greatly increases coronary risk, mild renal impairment is not usually considered a major risk factor." | 1.35 | Relations between markers of renal function, coronary risk factors and the occurrence and severity of coronary artery disease. ( Moriatis, M; Naidoo, D; Salonikas, C; Sim, AS; Wang, J; Wang, XL; Wilcken, DE, 2008) |
| "Reduced bioavailability of nitric oxide (NO) is thought to play an important role in progression of renal damage." | 1.33 | Asymmetric dimethylarginine and progression of chronic kidney disease: the mild to moderate kidney disease study. ( Bode-Böger, SM; Fliser, D; Haller, H; Kielstein, JT; Kronenberg, F; Morath, C; Ritz, E, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 14 (63.64) | 29.6817 |
| 2010's | 7 (31.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Locsey, L | 1 |
| Seres, I | 1 |
| Sztanek, F | 1 |
| Harangi, M | 1 |
| Padra, J | 1 |
| Kovacs, D | 1 |
| Fedor, R | 1 |
| Asztalos, L | 1 |
| Paragh, G | 1 |
| Kocyigit, I | 1 |
| Unal, A | 1 |
| Gungor, O | 1 |
| Orscelik, O | 1 |
| Eroglu, E | 1 |
| Dogan, E | 1 |
| Sen, A | 1 |
| Yasan, M | 1 |
| Hayri Sipahioglu, M | 1 |
| Tokgoz, B | 1 |
| Dogan, A | 1 |
| Oymak, O | 1 |
| Radenkovic, M | 1 |
| Stojanovic, M | 1 |
| Prostran, M | 1 |
| Heunisch, F | 1 |
| Chaykovska, L | 1 |
| von Einem, G | 1 |
| Alter, M | 1 |
| Dschietzig, T | 1 |
| Kretschmer, A | 1 |
| Kellner, KH | 1 |
| Hocher, B | 1 |
| Mangoni, AA | 1 |
| Meinitzer, A | 1 |
| Kielstein, JT | 2 |
| Pilz, S | 1 |
| Drechsler, C | 1 |
| Ritz, E | 2 |
| Boehm, BO | 1 |
| Winkelmann, BR | 1 |
| März, W | 1 |
| Toyohara, T | 1 |
| Abe, T | 1 |
| Ronden, RA | 1 |
| Houben, AJ | 1 |
| Teerlink, T | 2 |
| Bakker, JA | 1 |
| Bierau, J | 1 |
| Stehouwer, CD | 1 |
| De Leeuw, PW | 1 |
| Kroon, AA | 1 |
| Nijveldt, RJ | 1 |
| Van Der Hoven, B | 1 |
| Siroen, MP | 1 |
| Kuik, DJ | 1 |
| Rauwerda, JA | 1 |
| van Leeuwen, PA | 1 |
| Vallance, P | 3 |
| Leiper, J | 3 |
| Fliser, D | 1 |
| Kronenberg, F | 1 |
| Morath, C | 1 |
| Bode-Böger, SM | 1 |
| Haller, H | 1 |
| Lluch, P | 1 |
| Mauricio, MD | 1 |
| Vila, JM | 1 |
| Segarra, G | 1 |
| Medina, P | 1 |
| Del Olmo, JA | 1 |
| Rodrigo, JM | 1 |
| Serra, MA | 1 |
| Anthony, S | 1 |
| Maas, R | 2 |
| Böger, RH | 1 |
| Schwedhelm, E | 1 |
| Quispe-Bravo, S | 1 |
| Skamira, C | 1 |
| Zoccali, C | 1 |
| Wilcken, DE | 2 |
| Wang, J | 2 |
| Sim, AS | 2 |
| Green, K | 1 |
| Wilcken, B | 1 |
| Wang, XL | 1 |
| Salonikas, C | 1 |
| Moriatis, M | 1 |
| Naidoo, D | 1 |
| Fujii, H | 1 |
| Takiuchi, S | 1 |
| Kawano, Y | 1 |
| Fukagawa, M | 1 |
| White, R | 1 |
| Barefield, D | 1 |
| Ram, S | 1 |
| Work, J | 1 |
| Al Banchaabouchi, M | 1 |
| Marescau, B | 1 |
| Possemiers, I | 1 |
| D'Hooge, R | 1 |
| Levillain, O | 1 |
| De Deyn, PP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Dexamethasone Implant on Retinal Nerve Fiber and Optic Disc Morphology in Patients With Diabetic Maculopathy[NCT03927118] | 43 participants (Actual) | Observational | 2018-02-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for n(g),n(g')-dimethyl-l-arginine and Renal Insufficiency
| Article | Year |
|---|---|
Endothelial Dysfunction in Renal Failure: Current Update.
Topics: Arginine; Endothelium, Vascular; Humans; Nitric Oxide; Oxidative Stress; Renal Insufficiency; Uremia | 2016 |
The emerging role of symmetric dimethylarginine in vascular disease.
Topics: Arginine; Cardiovascular Diseases; Homeostasis; Humans; Nitric Oxide; Nitric Oxide Synthase Type III | 2009 |
[Analysis of transporter function and development to clinical application].
Topics: Aconitic Acid; Animals; Arginine; Guanidines; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors | 2011 |
Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathway.
Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; | 2004 |
Endogenous production of nitric oxide synthase inhibitors.
Topics: Arginine; Enzyme Inhibitors; Humans; Isoenzymes; Nitric Oxide Synthase; omega-N-Methylarginine; Prot | 2005 |
Pharmacotherapies and their influence on asymmetric dimethylargine (ADMA).
Topics: Amidohydrolases; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; | 2005 |
Asymmetric dimethylarginine (ADMA): a cardiovascular and renal risk factor on the move.
Topics: Arginine; Cardiovascular Diseases; Humans; Renal Insufficiency; Risk Factors | 2006 |
2 trials available for n(g),n(g')-dimethyl-l-arginine and Renal Insufficiency
| Article | Year |
|---|---|
Effects of dialysis solution on the cardiovascular function in peritoneal dialysis patients.
Topics: Adult; Aged; Arginine; Biomarkers; Blood Flow Velocity; Blood Pressure; Blood Pressure Monitoring, A | 2015 |
Symmetrical and asymmetrical dimethylarginine as predictors for mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health study.
Topics: Aged; Arginine; Biomarkers; Cardiovascular Diseases; Coronary Angiography; Coronary Disease; Female; | 2011 |
13 other studies available for n(g),n(g')-dimethyl-l-arginine and Renal Insufficiency
| Article | Year |
|---|---|
Relationship between serum paraoxonase and homocysteine thiolactonase activity, adipokines, and asymmetric dimethyl arginine concentrations in renal transplant patients.
Topics: Adipokines; Adult; Aged; Arginine; Aryldialkylphosphatase; Atherosclerosis; Biomarkers; C-Reactive P | 2013 |
ADMA predicts major adverse renal events in patients with mild renal impairment and/or diabetes mellitus undergoing coronary angiography.
Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Contrast Media; Coronary Angiography; Diabetes Mellit | 2017 |
Reduced renal plasma clearance does not explain increased plasma asymmetric dimethylarginine in hypertensive subjects with mild to moderate renal insufficiency.
Topics: Adult; Aged; Arginine; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Kidney Func | 2012 |
Asymmetrical dimethylarginine (ADMA) in critically ill patients: high plasma ADMA concentration is an independent risk factor of ICU mortality.
Topics: Adult; Aged; Analysis of Variance; Arginine; Critical Illness; Cross-Sectional Studies; Enzyme Inhib | 2003 |
Asymmetric dimethylarginine and progression of chronic kidney disease: the mild to moderate kidney disease study.
Topics: Adult; Arginine; Creatinine; Disease Progression; Female; Glomerular Filtration Rate; Hemoglobins; H | 2005 |
Asymmetric dimethylarginine and kidney disease--marker or mediator?
Topics: Animals; Arginine; Biomarkers; Humans; Kidney; Kidney Diseases; Nitric Oxide; Renal Insufficiency; R | 2005 |
Accumulation of symmetric dimethylarginine in hepatorenal syndrome.
Topics: Arginine; Case-Control Studies; Creatinine; Fibrosis; Hepatorenal Syndrome; Humans; Kidney; Liver; M | 2006 |
ADMA and oxidative stress may relate to the progression of renal disease: rationale and design of the VIVALDI study.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Ar | 2005 |
Asymmetric dimethylarginine in homocystinuria due to cystathionine beta-synthase deficiency: relevance of renal function.
Topics: Adult; Arginine; Creatinine; Cystathionine beta-Synthase; Cystatin C; Cystatins; Female; Homocystein | 2006 |
Relations between markers of renal function, coronary risk factors and the occurrence and severity of coronary artery disease.
Topics: Age Factors; Aged; Arginine; Biomarkers; Cohort Studies; Coronary Artery Disease; Cystatin C; Cystat | 2008 |
Putative role of asymmetric dimethylarginine in microvascular disease of kidney and heart in hypertensive patients.
Topics: Aged; Arginine; Carotid Arteries; Echocardiography; Female; Glomerular Filtration Rate; Heart Diseas | 2008 |
Peritoneal dialysis solutions reverse the hemodynamic effects of nitric oxide synthesis inhibitors.
Topics: Animals; Arginine; Dialysis Solutions; Enzyme Inhibitors; Hemodynamics; Male; Mesenteric Arteries; N | 1995 |
NG, NG-dimethylarginine and NG, NG-dimethylarginine in renal insufficiency.
Topics: Aged; Aged, 80 and over; Animals; Arginine; Blood Urea Nitrogen; Creatinine; Female; Humans; Isomeri | 2000 |