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n(g),n(g')-dimethyl-l-arginine and Pulmonary Embolism

n(g),n(g')-dimethyl-l-arginine has been researched along with Pulmonary Embolism in 4 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Pulmonary Embolism: Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.

Research Excerpts

ExcerptRelevanceReference
"We aimed to analyze the pre- and posttreatment serum asymmetric dimethylarginine (ADMA), nitrate (NO(3)), vitamin B(12) and homocysteine levels in pulmonary embolism (PTE) patients and to determine the prognostic value of these variables in predicting chronic thromboembolic pulmonary hypertension (CTEPH)."7.77Serum asymmetric dimethylarginine, nitrate, vitamin B(12), and homocysteine levels in individuals with pulmonary embolism. ( Altın, R; Altuntaş, M; Atalay, F; Can, M; Tor, M, 2011)
"We determined the levels of some heat shock proteins (HSP27, HSP70, and HSP90), L-arginine, asymmetric dimethylarginine (ADMA), and symmetric dimethylarginine (SDMA) levels in patients with acute pulmonary embolism."3.83Assessment of heat shock proteins and endothelial dysfunction in acute pulmonary embolism. ( Deveci, F; İn, E; Kaman, D, 2016)
"We aimed to analyze the pre- and posttreatment serum asymmetric dimethylarginine (ADMA), nitrate (NO(3)), vitamin B(12) and homocysteine levels in pulmonary embolism (PTE) patients and to determine the prognostic value of these variables in predicting chronic thromboembolic pulmonary hypertension (CTEPH)."3.77Serum asymmetric dimethylarginine, nitrate, vitamin B(12), and homocysteine levels in individuals with pulmonary embolism. ( Altın, R; Altuntaş, M; Atalay, F; Can, M; Tor, M, 2011)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kline, JA1
Watts, J1
Courtney, D1
Lee, YY1
Hwang, S1
Halici, B1
Sarinc Ulasli, S1
Günay, E1
Nural, S1
Sen, S1
Akar, O1
Celik, S1
Unlu, M1
İn, E1
Deveci, F1
Kaman, D1
Altuntaş, M1
Atalay, F1
Can, M1
Altın, R1
Tor, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Expired CO2/O2 Analysis to Diagnose Pulmonary Embolism[NCT00368836]Phase 2/Phase 3475 participants (Actual)Interventional2006-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Phase II: Probability of Pulmonary Embolism Diagnosis by D-dimer Alone vs. D-Dimer Plus CO2/O2 for Pulmonary Embolism Diagnosed by CT Scan.

D-dimer > 499 ng/ml, etCO2/O2 < 0.28, Pulmonary Embolism diagnosed by CT scan (NCT00368836)
Timeframe: Measured at 45 days

Interventionprobability of PE diagnosis (Number)
CO2/O2 Plus D-dimer0.32
D-dimer0.17

Phase I: Percentage Change in the Postoperative End Tidal CO2/O2 Ratio and D-dimer Concentration Relative to the Preoperative Measurement

Median postoperative change in end tidal CO2/O2 ratio calculated as 100% * [(postoperative-preoperative)/(preoperative)] (NCT00368836)
Timeframe: Pre-op measurement: the morning of surgery. Post-op measurement: the latter of postoperative day 3 or hospital discharge

Interventionpercent change (Median)
end tidal CO2/O2 ratioD-dimer concentration
BreathScreen PE0136

Other Studies

4 other studies available for n(g),n(g')-dimethyl-l-arginine and Pulmonary Embolism

ArticleYear
Severe pulmonary embolism decreases plasma L-arginine.
    The European respiratory journal, 2014, Volume: 43, Issue:3

    Topics: Arginase; Arginine; Chromatography, High Pressure Liquid; Echocardiography, Doppler; Hemolysis; Huma

2014
Assessment of inflammatory biomarkers and oxidative stress in pulmonary thromboembolism: follow-up results.
    Inflammation, 2014, Volume: 37, Issue:4

    Topics: Adult; Aged; Antioxidants; Arginine; Case-Control Studies; Female; Follow-Up Studies; Humans; Hypoxi

2014
Assessment of heat shock proteins and endothelial dysfunction in acute pulmonary embolism.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2016, Volume: 27, Issue:4

    Topics: Acute Disease; Adult; Aged; Arginine; Biomarkers; Case-Control Studies; Endothelium, Vascular; Femal

2016
Serum asymmetric dimethylarginine, nitrate, vitamin B(12), and homocysteine levels in individuals with pulmonary embolism.
    Mediators of inflammation, 2011, Volume: 2011

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Female; Homocysteine; Humans; Male; Middle Aged; Nitr

2011