Page last updated: 2024-10-17

n(g),n(g')-dimethyl-l-arginine and Pregnancy

n(g),n(g')-dimethyl-l-arginine has been researched along with Pregnancy in 83 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Resveratrol, a phytochemical, has shown antioxidant properties and potential benefits in hypertension."8.02Maternal resveratrol therapy protected adult rat offspring against hypertension programmed by combined exposures to asymmetric dimethylarginine and trimethylamine-N-oxide. ( Chan, JYH; Chang-Chien, GP; Hou, CY; Hsu, CN; Lee, CT; Lin, S; Tain, YL, 2021)
"To evaluate the sequential trend of asymmetric dimethylarginine (ADMA), placental growth factor (PLGF) and pentraxin 3 (PTX 3) in pregnancies developing preeclampsia (PE) as compared to healthy pregnancy (HP) and to estimate their predictive value for development of PE later in pregnancy."7.88Estimation of asymmetric dimethylarginine (ADMA), placental growth factor (PLGF) and pentraxin 3 (PTX 3) in women with preeclampsia. ( Deepak, KK; Garg, P; Jaryal, AK; Kachhawa, G; Kriplani, A, 2018)
"Our previous study suggested that a lower l-arginine level (<70μM) at early gestation is associated with pregnancy-induced hypertension."7.85Association of serum asymmetric dimethylarginine, homocysteine, and l-arginine concentrations during early pregnancy with hypertensive disorders of pregnancy. ( Imai, K; Kajiyama, H; Kikkawa, F; Kotani, T; Maruta, E; Mitsui, T; Nakano, T; Nawa, A; Niwa, Y; Sumigama, S; Tamakoshi, K; Tsuda, H; Wang, J; Yamashita, M; Yoshida, S, 2017)
"To evaluate the usefulness of serial determinations of asymmetric dimethylarginine (ADMA) and homocysteine (Hcy) concentrations during pregnancy to predict pre-eclampsia, taking into account maternal obesity and B vitamin status."7.81Serial determinations of asymmetric dimethylarginine and homocysteine during pregnancy to predict pre-eclampsia: a longitudinal study. ( Hinojosa-Cruz, JC; Leaños-Miranda, A; López-Alarcón, M; Martínez-Basila, A; Montalvo-Velarde, I; Vital-Reyes, VS, 2015)
" Asymmetric dimethylarginine (ADMA) is increased in diabetes mellitus, kidney disease, and hypertension."7.79Asymmetric dimethylarginine is associated with developmental programming of adult kidney disease and hypertension in offspring of streptozotocin-treated mothers. ( Hsu, CN; Huang, LT; Lee, CT; Lee, WC; Lin, CY; Tain, YL, 2013)
"These findings provide support for the hypothesis that elevated levels of asymmetric dimethylarginine in pregnancy complicated by preeclampsia are associated with elevated homocysteine levels."7.79Differences in the association between maternal serum homocysteine and ADMA levels in women with pregnancies complicated by preeclampsia and/or intrauterine growth restriction. ( Laskowska, K; Laskowska, M; Oleszczuk, J, 2013)
"The aim of this study was to investigate maternal asymmetric dimethylarginine (ADMA) concentrations at the three trimesters of pregnancy in uncomplicated pregnancies and in women who developed preeclampsia or had small for gestational age infants (SGA) without preeclampsia."7.78Levels of asymmetric dimethylarginine throughout normal pregnancy and in pregnancies complicated with preeclampsia or had a small for gestational age baby. ( Batakis, E; Botsis, D; Eleftheriades, M; Haliassos, A; Hassiakos, D; Rizos, D; Rizou, M, 2012)
" We analyzed the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and asymmetric dimethylarginine (ADMA) in 55 Turkish patients with PE without fetal growth retardation (FGR) and in 54 healthy pregnant women."7.76Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and plasma concentrations of asymmetric dimethylarginine in Turkish pre-eclamptic women without fetal growth retardation. ( Ateş, K; Ilhan, N; Kafkasli, A; Kaman, D; Turan, F, 2010)
"The purpose of this study was to investigate maternal plasma concentrations of asymmetric dimethylarginine (ADMA) in mid pregnancy and at the time of disease in women who experience preeclampsia, compared with women with uncomplicated pregnancies and women with small-for-gestational-age infants."7.74Elevated asymmetric dimethylarginine concentrations precede clinical preeclampsia, but not pregnancies with small-for-gestational-age infants. ( Frank, MP; Harger, G; Markovic, N; Powers, RW; Roberts, JM; Speer, PD, 2008)
"Preeclampsia is a serious, pregnancy-specific, multi-organ disease process of compound aetiology."6.61The Role of Nitric Oxide, ADMA, and Homocysteine in The Etiopathogenesis of Preeclampsia-Review. ( Dymara-Konopka, W; Laskowska, M, 2019)
"Preeclampsia is a major cause of maternal and neonatal morbidity and mortality worldwide."6.46The role of nitric oxide synthase inhibition by asymmetric dimethylarginine in the pathophysiology of preeclampsia. ( Böger, RH; Diemert, A; Hecher, K; Lüneburg, N; Maas, R; Schwedhelm, E, 2010)
" These data define a role for dysregulation of NO biosynthetic pathways in the pathogenesis of MIP and support the evaluation of interventions to enhance l-arginine bioavailability as strategies to improve birth outcomes."5.48Malaria in pregnancy alters l-arginine bioavailability and placental vascular development. ( Cahill, LS; Conroy, AL; Elphinstone, R; Gamble, JL; Gazdzinski, LM; Kain, KC; Kalilani-Phiri, L; Madanitsa, M; McDonald, CR; Mwapasa, V; Philson, AC; Sled, JG; Ter Kuile, FO; Zhong, KJY, 2018)
"Preeclampsia is associated with an imbalance in vasoactive factors, including nitric oxide (NO), hydrogen sulfide (H2S), and renin-angiotensin system (RAS)."5.43N-Acetylcysteine Prevents Programmed Hypertension in Male Rat Offspring Born to Suramin-Treated Mothers. ( Hsu, CN; Lee, CT; Lin, YJ; Tain, YL; Tsai, CC, 2016)
"Decreased DDAH and HO with preeclampsia suggest that they are important points in the regulatory pathways of NO and CO production that are altered in preeclampsia."5.39Nitric oxide and carbon monoxide production and metabolism in preeclampsia. ( Chan, K; Chen, DB; Ehsanipoor, RM; Fitzmaurice, LE; Fortson, W; Liao, WX; Wing, DA, 2013)
"Preeclampsia is a syndrome characterized by hypertension and proteinuria."5.37The role of asymmetric dimethyl arginine and oxidant/antioxidant system in preeclampsia. ( Akalin, S; Akgul, EO; Alacam, H; Aydin, I; Cakir, E; Danisman, N; Deren, O; Dikmen, ZG; Dogan, P; Keskin, U; Kurt, YG; Polat, B; Yaman, H, 2011)
"Preeclampsia is a leading cause of intrauterine growth restriction and preterm birth."5.35Asymmetric dimethylarginine in the maternal and fetal circulation in preeclampsia. ( Braekke, K; Harsem, NK; Staff, AC; Ueland, PM, 2009)
" The reduced bioavailability of endothelium-derived nitric oxide (NO) may play a role in endothelial vasodilator dysfunction and the structural changes that are characteristic of GCAD."5.33Dimethylarginine dimethylaminohydrolase overexpression suppresses graft coronary artery disease. ( Cooke, JP; Gunawan, F; Jacobi, J; Robbins, RC; Sydow, K; Tanaka, M; Tsao, PS, 2005)
"Asymmetric dimethylarginine (ADMA) is a competitive endogenous inhibitor of nitric oxide synthase with a key role in the pathophysiology of endothelial dysfunction, in the progression of atherosclerosis and in cardiovascular diseases."4.91Asymmetric Dimethylarginine: Clinical Significance and Novel Therapeutic Approaches. ( Georgakis, MK; Latsios, G; Oikonomou, E; Papageorgiou, N; Papaioannou, S; Siasos, G; Tousoulis, D; Zaromitidou, M, 2015)
"Resveratrol, a phytochemical, has shown antioxidant properties and potential benefits in hypertension."4.02Maternal resveratrol therapy protected adult rat offspring against hypertension programmed by combined exposures to asymmetric dimethylarginine and trimethylamine-N-oxide. ( Chan, JYH; Chang-Chien, GP; Hou, CY; Hsu, CN; Lee, CT; Lin, S; Tain, YL, 2021)
"To evaluate the sequential trend of asymmetric dimethylarginine (ADMA), placental growth factor (PLGF) and pentraxin 3 (PTX 3) in pregnancies developing preeclampsia (PE) as compared to healthy pregnancy (HP) and to estimate their predictive value for development of PE later in pregnancy."3.88Estimation of asymmetric dimethylarginine (ADMA), placental growth factor (PLGF) and pentraxin 3 (PTX 3) in women with preeclampsia. ( Deepak, KK; Garg, P; Jaryal, AK; Kachhawa, G; Kriplani, A, 2018)
"Our previous study suggested that a lower l-arginine level (<70μM) at early gestation is associated with pregnancy-induced hypertension."3.85Association of serum asymmetric dimethylarginine, homocysteine, and l-arginine concentrations during early pregnancy with hypertensive disorders of pregnancy. ( Imai, K; Kajiyama, H; Kikkawa, F; Kotani, T; Maruta, E; Mitsui, T; Nakano, T; Nawa, A; Niwa, Y; Sumigama, S; Tamakoshi, K; Tsuda, H; Wang, J; Yamashita, M; Yoshida, S, 2017)
" Maternal characteristics, uterine artery pulsatility index (UtA-PI), ductus venosus pulsatility index (DV-PI) and serum biomarkers including pregnancy associated plasma protein - A (PAPP-A), placental growth factor (PlGF), soluble fms-like tyrosine kinase 1 (sFlt-1), s-Flt-1/PLGF ratio, asymmetric dimethylarginine (ADMA), matrix metalloproteinase 9 (MMP-9), neutrophil gelatinase-associated lipocalin (NGAL) and MMP-9/NGAL complex were recorded."3.83Prediction of pre-eclampsia combining NGAL and other biochemical markers with Doppler in the first and/or second trimester of pregnancy. A pilot study. ( Eleftheriades, MI; Haliassos, AD; Karampas, GA; Mastorakos, GP; Metallinou, DK; Panoulis, KC; Rizos, DA; Rizou, MD, 2016)
"To evaluate the usefulness of serial determinations of asymmetric dimethylarginine (ADMA) and homocysteine (Hcy) concentrations during pregnancy to predict pre-eclampsia, taking into account maternal obesity and B vitamin status."3.81Serial determinations of asymmetric dimethylarginine and homocysteine during pregnancy to predict pre-eclampsia: a longitudinal study. ( Hinojosa-Cruz, JC; Leaños-Miranda, A; López-Alarcón, M; Martínez-Basila, A; Montalvo-Velarde, I; Vital-Reyes, VS, 2015)
"These findings provide support for the hypothesis that elevated levels of asymmetric dimethylarginine in pregnancy complicated by preeclampsia are associated with elevated homocysteine levels."3.79Differences in the association between maternal serum homocysteine and ADMA levels in women with pregnancies complicated by preeclampsia and/or intrauterine growth restriction. ( Laskowska, K; Laskowska, M; Oleszczuk, J, 2013)
"The present case-control study was undertaken to investigate l-arginine metabolism in pregnant women with early-onset and late-onset pre-eclampsia."3.79L-arginine metabolism in early-onset and late-onset pre-eclamptic pregnancies. ( Bode-Böger, SM; Bódis, J; Hantosi, E; Kovács, GL; Martens-Lobenhoffer, J; Molnár, G; Sulyok, E; Tamás, P, 2013)
" Asymmetric dimethylarginine (ADMA) is increased in diabetes mellitus, kidney disease, and hypertension."3.79Asymmetric dimethylarginine is associated with developmental programming of adult kidney disease and hypertension in offspring of streptozotocin-treated mothers. ( Hsu, CN; Huang, LT; Lee, CT; Lee, WC; Lin, CY; Tain, YL, 2013)
"The aim of this study was to investigate maternal asymmetric dimethylarginine (ADMA) concentrations at the three trimesters of pregnancy in uncomplicated pregnancies and in women who developed preeclampsia or had small for gestational age infants (SGA) without preeclampsia."3.78Levels of asymmetric dimethylarginine throughout normal pregnancy and in pregnancies complicated with preeclampsia or had a small for gestational age baby. ( Batakis, E; Botsis, D; Eleftheriades, M; Haliassos, A; Hassiakos, D; Rizos, D; Rizou, M, 2012)
"02) rose with fetal growth restriction while asymmetric dimethylarginine decreased (p = 0."3.78Compensatory feto-placental upregulation of the nitric oxide system during fetal growth restriction. ( Begliuomini, S; Boldrini, A; Casarosa, E; Coceani, F; Fink, B; Genazzani, AR; Ghirri, P; Pisaneschi, S; Ripoli, A; Sanchez, AM; Simoncini, T; Strigini, FA, 2012)
"We aimed to evaluate plasma asymmetric dimethylarginine (ADMA) concentrations and its relation with insulin sensitivity/resistance indices in pregnant women with different degrees of carbohydrate intolerance."3.77Asymmetric dimethylarginine level in hyperglycemic gestation. ( Kafkasli, A; Karabulut, AB; Sertkaya, AC; Turkcuoglu, I, 2011)
" In our study, we investigated ADMA, hCRP, and homocysteine concentrations in women with gestational diabetes mellitus (GDM) and normal glucose tolerance (NGT) during late pregnancy."3.76Asymmetric dimethylarginine concentrations are elevated in women with gestational diabetes. ( Akturk, M; Altinova, A; Arslan, M; Buyukkagnici, U; Danisman, N; Dincel, A; Mert, I; Sargin, A, 2010)
" We analyzed the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and asymmetric dimethylarginine (ADMA) in 55 Turkish patients with PE without fetal growth retardation (FGR) and in 54 healthy pregnant women."3.76Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and plasma concentrations of asymmetric dimethylarginine in Turkish pre-eclamptic women without fetal growth retardation. ( Ateş, K; Ilhan, N; Kafkasli, A; Kaman, D; Turan, F, 2010)
"Evidence exists for an association between use of vitamin supplements with folic acid in early pregnancy and reduced risk for offspring with cleft lip with/without cleft palate (CLP)."3.75Nested case-control study of one-carbon metabolites in mid-pregnancy and risks of cleft lip with and without cleft palate. ( Blom, H; Carmichael, SL; Finnell, RH; Shaw, GM; Ueland, PM; Vollset, SE; Yang, W, 2009)
" However, it is unknown whether excess weight, insulin resistance, and asymmetric dimethylarginine (ADMA)--an endogenous nitric oxide (NO) synthase inhibitor--also contribute to the vascular changes observed in these patients."3.74Impaired vascular nitric oxide bioactivity in women with previous gestational diabetes. ( Kautzky-Willer, A; Langenberger, H; Mittermayer, F; Pacini, G; Pleiner, J; Schaller, G; Tura, A; Winzer, C; Wolzt, M, 2007)
"The purpose of this study was to investigate maternal plasma concentrations of asymmetric dimethylarginine (ADMA) in mid pregnancy and at the time of disease in women who experience preeclampsia, compared with women with uncomplicated pregnancies and women with small-for-gestational-age infants."3.74Elevated asymmetric dimethylarginine concentrations precede clinical preeclampsia, but not pregnancies with small-for-gestational-age infants. ( Frank, MP; Harger, G; Markovic, N; Powers, RW; Roberts, JM; Speer, PD, 2008)
"An endogenous inhibitor of nitric oxide synthase (NOS), NG,NG dimethylarginine (asymmetric dimethylarginine, ADMA), which is present in human plasma and urine, has been reported to be elevated in the plasma of women with pre-eclampsia."3.69Effect of asymmetric dimethyl arginine on nitric oxide synthase activity in normal and pre-eclamptic placentae. ( Brennecke, SP; Di Iulio, JL; Gude, NM; King, RG, 1995)
"Since women with gestational diabetes mellitus (GDM) are at high risk of future CVD, we conducted a systematic review and meta-analysis to compare ADMA concentrations between women with and without GDM during pregnancy and postpartum."3.01Asymmetric dimethylarginine and gestational diabetes mellitus: a systematic review and meta-analysis. ( Andraweera, PH; Arstall, MA; Kosmider, L; Lassi, ZS; Tiong, P, 2023)
"Preeclampsia is a serious, pregnancy-specific, multi-organ disease process of compound aetiology."2.61The Role of Nitric Oxide, ADMA, and Homocysteine in The Etiopathogenesis of Preeclampsia-Review. ( Dymara-Konopka, W; Laskowska, M, 2019)
"Low and high birth weights have been linked to increased susceptibility to cardiovascular and metabolic alterations."2.50Is asymmetric dimethylarginine associated with being born small and large for gestational age? ( Chiarelli, F; Chiavaroli, V; de Giorgis, T; Diesse, L; Giannini, C; Marcovecchio, ML; Mohn, A, 2014)
"Preeclampsia is a major cause of maternal and neonatal morbidity and mortality worldwide."2.46The role of nitric oxide synthase inhibition by asymmetric dimethylarginine in the pathophysiology of preeclampsia. ( Böger, RH; Diemert, A; Hecher, K; Lüneburg, N; Maas, R; Schwedhelm, E, 2010)
"Elevated ADMA levels in preeclampsia are seen before clinical symptoms have developed; these findings suggest that ADMA has a role in the pathogenesis of preeclampsia."2.43Endogenous inhibitors of nitric oxide and preeclampsia: a review. ( Dekker, G; Jeffries, B; Slaghekke, F, 2006)
"Smoking during pregnancy has harmful effects on the fetus and infant."1.62Evaluation of Plasma Asymmetric Dimethylarginine Levels and Abdominal Aortic Intima-Media Thickness in Infants of Smoker Mothers. ( Arslan, D; Deniz, CD; Gunenc, O; Ozcelik, HS; Uysal, C; Vatansev, H, 2021)
" These data define a role for dysregulation of NO biosynthetic pathways in the pathogenesis of MIP and support the evaluation of interventions to enhance l-arginine bioavailability as strategies to improve birth outcomes."1.48Malaria in pregnancy alters l-arginine bioavailability and placental vascular development. ( Cahill, LS; Conroy, AL; Elphinstone, R; Gamble, JL; Gazdzinski, LM; Kain, KC; Kalilani-Phiri, L; Madanitsa, M; McDonald, CR; Mwapasa, V; Philson, AC; Sled, JG; Ter Kuile, FO; Zhong, KJY, 2018)
"Since the diagnosis of gestational diabetes mellitus (GDM) identifies a patient population at increased future risk of cardiovascular disease later in life, we sought to characterize arginine metabolism in women with and without a history of recent GDM."1.46Asymmetric dimethylarginine and arginine metabolites in women with and without a history of gestational diabetes. ( Arya, S; Connelly, PW; Hanley, AJ; Retnakaran, R; Sermer, M; Ye, C; Zinman, B, 2017)
"Early-onset and late-onset preeclampsia are both characterized by increased systemic vascular resistance and elevated levels of nitric oxide synthesis inhibitors."1.46Systemic vascular resistance and endogenous inhibitors of nitric oxide synthesis in early- compared to late-onset preeclampsia: preliminary findings. ( Lackner, HK; Lucovnik, M; Moertl, MG; Papousek, I; Roessler, A; Schmid-Zalaudek, K; Schulter, G, 2017)
"Preeclampsia is associated with an imbalance in vasoactive factors, including nitric oxide (NO), hydrogen sulfide (H2S), and renin-angiotensin system (RAS)."1.43N-Acetylcysteine Prevents Programmed Hypertension in Male Rat Offspring Born to Suramin-Treated Mothers. ( Hsu, CN; Lee, CT; Lin, YJ; Tain, YL; Tsai, CC, 2016)
"Preeclampsia is a pregnancy-related pathological condition triggered by an abnormal placentation which produces endothelial dysfunction (ED)."1.42[Interactions between markers of endothelial damage (homocysteine and asymmetric dimethylarginine) and antioxidants and B-vitamins in preeclamptic women]. ( Hinojosa-Cruz, JC; López-Alarcón, M; Montalvo-Velarde, I; Puellotamara, E; Vital-Reyes, VS, 2015)
"Forty-four women developed preeclampsia."1.42First-Trimester Maternal Serum Levels of sFLT1, PGF and ADMA Predict Preeclampsia. ( Bian, Z; Duan, T; Shixia, C, 2015)
"Carotid atherosclerosis was evaluated by ultrasonographically determined intima-media thickness (IMT)."1.42Asymmetric dimethylarginine is associated with high-sensitivity C-reactive protein and early carotid atherosclerosis in women with previous gestational diabetes mellitus. ( Li, D; Shao, Y; Xia, W; Xu, L; Xu, W; Zhang, C, 2015)
"Our results allow the conclusion that impaired NO bioavailability in pregnancies complicated by severe preeclampsia and/or IUGR result not from a reduced level or activity of eNOS or from its disturbed intracellular transport, but from increased ADMA levels, an endogenous inhibitor of the enzyme eNOS."1.42The relation of maternal serum eNOS, NOSTRIN and ADMA levels with aetiopathogenesis of preeclampsia and/or intrauterine fetal growth restriction. ( Laskowska, K; Laskowska, M; Oleszczuk, J, 2015)
"Decreased DDAH and HO with preeclampsia suggest that they are important points in the regulatory pathways of NO and CO production that are altered in preeclampsia."1.39Nitric oxide and carbon monoxide production and metabolism in preeclampsia. ( Chan, K; Chen, DB; Ehsanipoor, RM; Fitzmaurice, LE; Fortson, W; Liao, WX; Wing, DA, 2013)
" The higher ADMA level after cesarean birth compared with vaginal birth may contribute to decreased nitric oxide production and bioavailability in neonatal vascular beds."1.38Birth by cesarean section is associated with elevated neonatal plasma levels of dimethylarginines. ( Bode-Böger, SM; Ertl, T; Martens-Lobenhoffer, J; Sulyok, E; Vida, G, 2012)
"The development of pulmonary hypertension is a common accompaniment of congenital heart disease (CHD) with increased pulmonary blood flow."1.38Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I. ( Aramburo, A; Black, SM; Fineman, JR; Kalkan, G; Kallarackal, S; Kumar, S; Rafikov, R; Rehmani, I; Sharma, S; Sun, X; Tian, J, 2012)
"Preeclampsia is a syndrome characterized by hypertension and proteinuria."1.37The role of asymmetric dimethyl arginine and oxidant/antioxidant system in preeclampsia. ( Akalin, S; Akgul, EO; Alacam, H; Aydin, I; Cakir, E; Danisman, N; Deren, O; Dikmen, ZG; Dogan, P; Keskin, U; Kurt, YG; Polat, B; Yaman, H, 2011)
"Preeclampsia is a leading cause of intrauterine growth restriction and preterm birth."1.35Asymmetric dimethylarginine in the maternal and fetal circulation in preeclampsia. ( Braekke, K; Harsem, NK; Staff, AC; Ueland, PM, 2009)
"Normal pregnancy is associated with changes in the immune system."1.35Maternal serum ADMA is not associated with proinflammatory cytokines or C-reactive protein during normal pregnancy. ( Heinonen, S; Heiskanen, N; Laitinen, T; Lyyra-Laitinen, T; Punnonen, K; Raitakari, OT; Saarelainen, H; Valtonen, P; Viikari, JS, 2009)
"From Jan."1.35[Relationship between changes of endogenous nitric oxide synthase inhibitor and hydrolase and initiation of pre-eclampsia]. ( Chen, DJ; Huang, YY; Liu, HS; Lu, XH; Yao, XB, 2009)
" The reduced bioavailability of endothelium-derived nitric oxide (NO) may play a role in endothelial vasodilator dysfunction and the structural changes that are characteristic of GCAD."1.33Dimethylarginine dimethylaminohydrolase overexpression suppresses graft coronary artery disease. ( Cooke, JP; Gunawan, F; Jacobi, J; Robbins, RC; Sydow, K; Tanaka, M; Tsao, PS, 2005)

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (6.02)18.2507
2000's22 (26.51)29.6817
2010's51 (61.45)24.3611
2020's5 (6.02)2.80

Authors

AuthorsStudies
Tiong, P3
Kosmider, L3
Lassi, ZS3
Arstall, MA3
Andraweera, PH3
Selanno, JF1
Riu, DS1
Tessy, T1
Chalid, MT1
Pelupessy, NU1
Hartono, E1
Ozcelik, HS1
Arslan, D2
Deniz, CD1
Gunenc, O1
Vatansev, H2
Uysal, C1
Dai, Y1
Li, TH1
He, X1
Yan, SB1
Gao, Y1
Chen, Y1
Hsu, CN5
Hou, CY1
Chang-Chien, GP1
Lin, S1
Chan, JYH1
Lee, CT4
Tain, YL6
Arya, S1
Ye, C1
Connelly, PW1
Hanley, AJ1
Sermer, M1
Zinman, B1
Retnakaran, R1
Lin, YJ2
Sheen, JM1
Lin, IC1
Yu, HR1
Huang, LT4
Lucovnik, M1
Lackner, HK1
Papousek, I1
Schmid-Zalaudek, K1
Schulter, G1
Roessler, A1
Moertl, MG1
Maruta, E1
Wang, J1
Kotani, T1
Tsuda, H1
Nakano, T1
Imai, K1
Sumigama, S1
Niwa, Y1
Mitsui, T1
Yoshida, S1
Yamashita, M1
Nawa, A1
Tamakoshi, K1
Kajiyama, H1
Kikkawa, F1
Tsikas, D3
Bollenbach, A1
Savvidou, MD2
Bjørke-Jenssen, A1
Ueland, PM3
Bjørke-Monsen, AL1
McDonald, CR1
Cahill, LS1
Gamble, JL1
Elphinstone, R1
Gazdzinski, LM1
Zhong, KJY1
Philson, AC1
Madanitsa, M1
Kalilani-Phiri, L1
Mwapasa, V1
Ter Kuile, FO1
Sled, JG1
Conroy, AL1
Kain, KC1
Garg, P1
Jaryal, AK1
Kachhawa, G1
Deepak, KK1
Kriplani, A1
Németh, B1
Murányi, E1
Hegyi, P1
Mátrai, P1
Szakács, Z1
Varjú, P1
Hamvas, S1
Tinusz, B1
Budán, F1
Czimmer, J1
Bérczi, B1
Erőss, B1
Gyöngyi, Z1
Kiss, I1
He, Q1
Liu, X1
Zhong, Y1
Xu, SS1
Zhang, ZM1
Tang, LL1
Zhang, LY1
Du, LZ1
Dymara-Konopka, W1
Laskowska, M5
El-Saka, MH1
Madi, NM1
Ibrahim, RR1
Alghazaly, GM1
Elshwaikh, S1
El-Bermawy, M1
Lee, WC2
Lin, CY1
Oran, B1
Cimen, D1
Guvenc, O1
Laskowska, K4
Terbosh, M1
Oleszczuk, J5
Tamás, P1
Bódis, J1
Sulyok, E3
Kovács, GL1
Hantosi, E1
Molnár, G1
Martens-Lobenhoffer, J3
Bode-Böger, SM3
Alpoim, PN1
Godoi, LC1
Freitas, LG1
Gomes, KB1
Dusse, LM1
Bassareo, PP1
Fanos, V1
Mussap, M1
Flore, G1
Noto, A1
Puddu, M1
Saba, L1
Mercuro, G1
Chiavaroli, V1
Diesse, L1
de Giorgis, T1
Giannini, C1
Marcovecchio, ML1
Chiarelli, F1
Mohn, A1
Xia, W1
Li, D1
Zhang, C1
Xu, L1
Xu, W1
Shao, Y1
Bian, Z1
Shixia, C1
Duan, T1
Tousoulis, D1
Georgakis, MK1
Oikonomou, E1
Papageorgiou, N1
Zaromitidou, M1
Latsios, G1
Papaioannou, S1
Siasos, G1
López-Alarcón, M2
Montalvo-Velarde, I2
Vital-Reyes, VS2
Hinojosa-Cruz, JC2
Leaños-Miranda, A1
Martínez-Basila, A1
Puellotamara, E1
Poniedziałek-Czajkowska, E1
Mierzyński, R1
Szymula, D1
Leszczyńska-Gorzelak, B2
Tsai, CC1
Mayer-Pickel, K1
Kolovetsiou-Kreiner, V1
Mörtl, MG1
Schlembach, D1
Eberhard, K1
Obermayer-Pietsch, B1
Lang, U1
Cervar-Zivkovic, M1
Karampas, GA1
Eleftheriades, MI1
Panoulis, KC1
Rizou, MD1
Haliassos, AD1
Metallinou, DK1
Mastorakos, GP1
Rizos, DA1
Mora-Fernández, C1
Jarque, A1
Getino, MA1
Sánchez, R1
Lozano, L1
Navarro, JF1
Telejko, B1
Zonenberg, A1
Kuzmicki, M1
Modzelewska, A1
Niedziolko-Bagniuk, K1
Ponurkiewicz, A1
Nikolajuk, A1
Gorska, M1
Valtonen, P1
Punnonen, K1
Saarelainen, H1
Heiskanen, N1
Raitakari, OT1
Viikari, JS1
Lyyra-Laitinen, T1
Laitinen, T1
Heinonen, S1
Huang, YY1
Yao, XB1
Lu, XH1
Liu, HS1
Chen, DJ1
Braekke, K1
Harsem, NK1
Staff, AC1
Shaw, GM1
Vollset, SE1
Carmichael, SL1
Yang, W1
Finnell, RH1
Blom, H1
Mao, D1
Che, J1
Li, K1
Han, S1
Yue, Q1
Zhu, L1
Zhang, W1
Li, L1
Böger, RH3
Diemert, A1
Schwedhelm, E2
Lüneburg, N1
Maas, R2
Hecher, K1
Sandrim, VC1
Palei, AC1
Metzger, IF1
Cavalli, RC1
Duarte, G1
Tanus-Santos, JE1
Turan, F1
Ilhan, N1
Kaman, D1
Ateş, K1
Kafkasli, A2
Akturk, M1
Altinova, A1
Mert, I1
Dincel, A1
Sargin, A1
Buyukkagnici, U1
Arslan, M1
Danisman, N2
Alfiero Bordigato, M1
Piva, D1
Di Gangi, IM1
Giordano, G1
Chiandetti, L1
Filippone, M1
Sertkaya, AC1
Turkcuoglu, I1
Karabulut, AB1
Rizos, D1
Eleftheriades, M1
Batakis, E1
Rizou, M1
Haliassos, A1
Hassiakos, D1
Botsis, D1
Alacam, H1
Dikmen, ZG1
Yaman, H1
Cakir, E1
Deren, O1
Akgul, EO1
Aydin, I1
Kurt, YG1
Keskin, U1
Akalin, S1
Polat, B1
Dogan, P1
Khalil, AA1
Akolekar, R1
Jordan, J1
Nicolaides, KH2
Vida, G2
Ertl, T2
Gumus, II1
Kargili, A1
Kaygusuz, I1
Derbent, A1
Karakurt, F1
Kasapoglu, B1
Uysal, S1
Sharma, S1
Sun, X1
Kumar, S1
Rafikov, R1
Aramburo, A1
Kalkan, G1
Tian, J1
Rehmani, I1
Kallarackal, S1
Fineman, JR1
Black, SM1
Demir, B1
Demir, S1
Pasa, S1
Guven, S1
Atamer, Y1
Atamer, A1
Kocyigit, Y1
Masoura, S1
Kalogiannidis, IA1
Gitas, G1
Goutsioulis, A1
Koiou, E1
Athanasiadis, A1
Vavatsi, N1
Ehsanipoor, RM1
Fortson, W1
Fitzmaurice, LE1
Liao, WX1
Wing, DA1
Chen, DB1
Chan, K1
Pisaneschi, S1
Strigini, FA1
Sanchez, AM1
Begliuomini, S1
Casarosa, E1
Ripoli, A1
Ghirri, P1
Boldrini, A1
Fink, B1
Genazzani, AR2
Coceani, F1
Simoncini, T2
Chedraui, P1
Solis, EJ1
Bocci, G1
Gopal, S1
Russo, E1
Escobar, GS1
Hidalgo, L1
Pérez-López, FR1
Mannella, P1
Hsieh, CS1
Chang, KA1
Mittermayer, F2
Mayer, BX1
Meyer, A1
Winzer, C2
Pacini, G2
Wagner, OF1
Wolzt, M2
Kautzky-Willer, A2
Maeda, T1
Yoshimura, T1
Okamura, H1
Hingorani, AD1
Frölich, JC1
Vallance, P3
Casas, JP1
López-Jaramillo, P1
Serrano, N1
Díaz, LA1
Leiper, J1
Tanaka, M1
Sydow, K1
Gunawan, F1
Jacobi, J1
Tsao, PS1
Robbins, RC1
Cooke, JP1
Herrmann, W1
Isber, S1
Obeid, R1
Herrmann, M1
Jouma, M1
Markov, KhM1
Slaghekke, F1
Dekker, G1
Jeffries, B1
Pleiner, J1
Langenberger, H1
Schaller, G1
Tura, A1
Speer, PD1
Powers, RW1
Frank, MP1
Harger, G1
Markovic, N1
Roberts, JM1
Tsukahara, H1
Ohta, N2
Tokuriki, S1
Nishijima, K1
Kotsuji, F1
Kawakami, H1
Sekine, K1
Nagasaka, H1
Mayumi, M1
Prefumo, F1
Thilaganathan, B1
Whitley, GS2
Fickling, SA1
Williams, D1
Nussey, SS1
King, RG1
Di Iulio, JL1
Gude, NM1
Brennecke, SP1
Chen, BM1
Xia, LW1
Zhao, RQ1
Egberts, J2
van den Bosch, N2
Brand, R1
Soederhuizen, P1
Ellis, J1
Wennerholm, UB1
Bengtsson, A1
Lilja, H1
Pettersson, A1
Sultan, B1
Wennergren, M1
Hagberg, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 1 Study of the Safety and Pharmacokinetics of Perioperative IV L-carnitine Administration in Patients With Congenital Heart Disease With Increased Pulmonary Blood Flow[NCT01825369]Phase 10 participants (Actual)Interventional2014-12-31Withdrawn (stopped due to Changes to cardiac surgery program)
Vascular Endothelial Growth Factor C/A 2578 Gene Polymorphism and Umbilical Artery Doppler in Preeclamptic Women[NCT03500588]290 participants (Actual)Observational2017-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

13 reviews available for n(g),n(g')-dimethyl-l-arginine and Pregnancy

ArticleYear
Asymmetric dimethylarginine and gestational diabetes mellitus: a systematic review and meta-analysis.
    Endocrine, 2023, Volume: 80, Issue:2

    Topics: Arginine; Cardiovascular Diseases; Diabetes, Gestational; Female; Humans; Postpartum Period; Pregnan

2023
Asymmetric dimethylarginine and gestational diabetes mellitus: a systematic review and meta-analysis.
    Endocrine, 2023, Volume: 80, Issue:2

    Topics: Arginine; Cardiovascular Diseases; Diabetes, Gestational; Female; Humans; Postpartum Period; Pregnan

2023
Asymmetric dimethylarginine and gestational diabetes mellitus: a systematic review and meta-analysis.
    Endocrine, 2023, Volume: 80, Issue:2

    Topics: Arginine; Cardiovascular Diseases; Diabetes, Gestational; Female; Humans; Postpartum Period; Pregnan

2023
Asymmetric dimethylarginine and gestational diabetes mellitus: a systematic review and meta-analysis.
    Endocrine, 2023, Volume: 80, Issue:2

    Topics: Arginine; Cardiovascular Diseases; Diabetes, Gestational; Female; Humans; Postpartum Period; Pregnan

2023
Asymmetric dimethylarginine levels in preeclampsia - Systematic review and meta-analysis.
    Placenta, 2018, Volume: 69

    Topics: Arginine; Biomarkers; Female; Humans; Pre-Eclampsia; Pregnancy

2018
The Role of Nitric Oxide, ADMA, and Homocysteine in The Etiopathogenesis of Preeclampsia-Review.
    International journal of molecular sciences, 2019, Jun-05, Volume: 20, Issue:11

    Topics: Arginine; Female; Homocysteine; Humans; Nitric Oxide; Pre-Eclampsia; Pregnancy; Signal Transduction

2019
Is asymmetric dimethylarginine associated with being born small and large for gestational age?
    Antioxidants & redox signaling, 2014, May-20, Volume: 20, Issue:15

    Topics: Arginine; Biomarkers; Birth Weight; Cardiovascular Diseases; Female; Gestational Age; Humans; Metabo

2014
Asymmetric Dimethylarginine: Clinical Significance and Novel Therapeutic Approaches.
    Current medicinal chemistry, 2015, Volume: 22, Issue:24

    Topics: Alzheimer Disease; Animals; Arginine; Cardiovascular Diseases; Diabetes Mellitus; Female; Humans; Hy

2015
[Novelties in the field of progression factors in chronic kidney disease].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2008, Volume: 28 Suppl 5

    Topics: Adult; Amidohydrolases; Animals; Arginine; Carbon; Cardiovascular Diseases; Chronic Disease; Clinica

2008
The role of nitric oxide synthase inhibition by asymmetric dimethylarginine in the pathophysiology of preeclampsia.
    Gynecologic and obstetric investigation, 2010, Volume: 69, Issue:1

    Topics: Arginine; Biomarkers; Endothelium, Vascular; Female; Humans; Nitric Oxide Synthase; Pre-Eclampsia; P

2010
Biomarkers in pre-eclampsia: a novel approach to early detection of the disease.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2012, Volume: 32, Issue:7

    Topics: Antigens, CD; Arginine; Biomarkers; Endoglin; Female; Galectins; Homocysteine; Humans; Leptin; Pre-E

2012
Roles of nitric oxide and asymmetric dimethylarginine in pregnancy and fetal programming.
    International journal of molecular sciences, 2012, Nov-09, Volume: 13, Issue:11

    Topics: Animals; Arginine; Female; Fetal Development; Humans; Metabolic Networks and Pathways; Nitric Oxide;

2012
[Asymmetrical methylarginine (ADMA) as a cardiovascular risk factor: epidemiological and prospective data].
    Deutsche medizinische Wochenschrift (1946), 2004, Apr-08, Volume: 129, Issue:15

    Topics: Adult; Aged; Aged, 80 and over; Animals; Arginine; Arteriosclerosis; Biomarkers; Cardiovascular Dise

2004
Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathway.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:6

    Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Cardiovascular Physiological Phenomena;

2004
[Molecular mechanisms of dysfunction of vascular endothelium].
    Kardiologiia, 2005, Volume: 45, Issue:12

    Topics: Adult; Animals; Apoptosis; Arginine; Atherosclerosis; Cardiovascular Diseases; Cells, Cultured; Chil

2005
Endogenous inhibitors of nitric oxide and preeclampsia: a review.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2006, Volume: 19, Issue:8

    Topics: Amidohydrolases; Arginine; Endothelium, Vascular; Female; Humans; Nitric Oxide; Nitric Oxide Synthas

2006

Other Studies

70 other studies available for n(g),n(g')-dimethyl-l-arginine and Pregnancy

ArticleYear
Maternal serum levels of asymmetric dimethylarginine in normal and preeclamptic pregnancies.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2020, Volume: 36, Issue:8

    Topics: Adult; Arginine; Case-Control Studies; Cross-Sectional Studies; Female; Fetal Growth Retardation; Hu

2020
Evaluation of Plasma Asymmetric Dimethylarginine Levels and Abdominal Aortic Intima-Media Thickness in Infants of Smoker Mothers.
    American journal of perinatology, 2021, Volume: 38, Issue:14

    Topics: Adult; Aorta, Abdominal; Arginine; Case-Control Studies; Cigarette Smoking; Echocardiography; Female

2021
The Effect and Mechanism of Asymmetric Dimethylarginine Regulating Trophoblastic Autophagy on Fetal Growth Restriction.
    Reproductive sciences (Thousand Oaks, Calif.), 2021, Volume: 28, Issue:7

    Topics: Adenine; Adult; Arginine; Autophagy; Beclin-1; Cell Line, Tumor; Female; Fetal Growth Retardation; H

2021
Maternal resveratrol therapy protected adult rat offspring against hypertension programmed by combined exposures to asymmetric dimethylarginine and trimethylamine-N-oxide.
    The Journal of nutritional biochemistry, 2021, Volume: 93

    Topics: Animals; Antioxidants; Arginine; Female; Gastrointestinal Microbiome; Hypertension; Methylamines; Pr

2021
Asymmetric dimethylarginine and arginine metabolites in women with and without a history of gestational diabetes.
    Journal of diabetes and its complications, 2017, Volume: 31, Issue:6

    Topics: Adult; Arginine; Cardiovascular Diseases; Diabetes, Gestational; Female; Follow-Up Studies; Glucose

2017
Resveratrol prevents the combined maternal plus postweaning high-fat-diets-induced hypertension in male offspring.
    The Journal of nutritional biochemistry, 2017, Volume: 48

    Topics: Animals; Arginine; Blood Pressure; Diet, High-Fat; Female; Hypertension; Male; Maternal Nutritional

2017
Systemic vascular resistance and endogenous inhibitors of nitric oxide synthesis in early- compared to late-onset preeclampsia: preliminary findings.
    Hypertension in pregnancy, 2017, Volume: 36, Issue:3

    Topics: Adult; Arginine; Case-Control Studies; Female; Humans; Pre-Eclampsia; Pregnancy; Vascular Resistance

2017
Association of serum asymmetric dimethylarginine, homocysteine, and l-arginine concentrations during early pregnancy with hypertensive disorders of pregnancy.
    Clinica chimica acta; international journal of clinical chemistry, 2017, Volume: 475

    Topics: Adult; Area Under Curve; Arginine; Biomarkers; Body Mass Index; Case-Control Studies; Female; Gestat

2017
Inverse correlation between maternal plasma asymmetric dimethylarginine (ADMA) and birthweight percentile in women with impaired placental perfusion: circulating ADMA as an NO-independent indicator of fetal growth restriction?
    Amino acids, 2018, Volume: 50, Issue:2

    Topics: Adult; Arginine; Biomarkers; Birth Weight; Female; Fetal Growth Retardation; Fetus; Gestational Age;

2018
Amniotic Fluid Arginine from Gestational Weeks 13 to 15 Is a Predictor of Birth Weight, Length, and Head Circumference.
    Nutrients, 2017, Dec-14, Volume: 9, Issue:12

    Topics: Adult; Amniotic Fluid; Arginine; Birth Weight; Dietary Supplements; Female; Fetal Growth Retardation

2017
Malaria in pregnancy alters l-arginine bioavailability and placental vascular development.
    Science translational medicine, 2018, 03-07, Volume: 10, Issue:431

    Topics: Animals; Arginine; Female; Humans; Malaria; Mice; Nitric Oxide; Placenta; Pregnancy; Pregnancy Outco

2018
Estimation of asymmetric dimethylarginine (ADMA), placental growth factor (PLGF) and pentraxin 3 (PTX 3) in women with preeclampsia.
    Pregnancy hypertension, 2018, Volume: 14

    Topics: Adult; Arginine; Biomarkers; C-Reactive Protein; Case-Control Studies; Disease Progression; Female;

2018
Arginine bioavailability and endothelin-1 system in the regulation of vascular function of umbilical vein endothelial cells from intrauterine growth restricted newborns.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2018, Volume: 28, Issue:12

    Topics: Adult; Amidohydrolases; Arginase; Arginine; Case-Control Studies; Cell Proliferation; Cells, Culture

2018
The ameliorative effect of angiotensin 1-7 on experimentally induced-preeclampsia in rats: Targeting the role of peroxisome proliferator-activated receptors gamma expression & asymmetric dimethylarginine.
    Archives of biochemistry and biophysics, 2019, 08-15, Volume: 671

    Topics: Angiotensin I; Animals; Arginine; Blood Pressure; Female; Oxidative Stress; Peptide Fragments; Place

2019
Asymmetric dimethylarginine is associated with developmental programming of adult kidney disease and hypertension in offspring of streptozotocin-treated mothers.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: Animals; Arginine; Blotting, Western; Electron Spin Resonance Spectroscopy; Female; Hypertension; Ki

2013
The usefulness of plasma asymmetric dimethylarginine (ADMA) levels and tissue doppler echocardiography for heart function in term infants born to mothers with gestational diabetes mellitus.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2013, Volume: 26, Issue:17

    Topics: Arginine; Case-Control Studies; Diabetes, Gestational; Echocardiography, Doppler; Female; Heart; Hum

2013
A comparison of maternal serum levels of endothelial nitric oxide synthase, asymmetric dimethylarginine, and homocysteine in normal and preeclamptic pregnancies.
    Medical science monitor : international medical journal of experimental and clinical research, 2013, Jun-05, Volume: 19

    Topics: Adult; Arginine; Case-Control Studies; Female; Homocysteine; Humans; Nitric Oxide Synthase Type III;

2013
L-arginine metabolism in early-onset and late-onset pre-eclamptic pregnancies.
    Scandinavian journal of clinical and laboratory investigation, 2013, Volume: 73, Issue:5

    Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Female; Fetal Blood; Humans; omega-N-Methylargini

2013
Assessment of L-arginine asymmetric 1 dimethyl (ADMA) in early-onset and late-onset (severe) preeclampsia.
    Nitric oxide : biology and chemistry, 2013, Sep-01, Volume: 33

    Topics: Arginine; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Nitric Oxide; Pre

2013
Urinary NGAL and hematic ADMA levels: an early sign of cardio-renal syndrome in young adults born preterm?
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2013, Volume: 26 Suppl 2

    Topics: Acute-Phase Proteins; Adolescent; Adult; Adult Children; Arginine; Cardio-Renal Syndrome; Case-Contr

2013
The relation of maternal serum eNOS, NOSTRIN and ADMA levels with aetiopathogenesis of preeclampsia and/or intrauterine fetal growth restriction.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2015, Volume: 28, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Adult; Arginine; Case-Control Studies; DNA-Binding Proteins; F

2015
Melatonin therapy prevents programmed hypertension and nitric oxide deficiency in offspring exposed to maternal caloric restriction.
    Oxidative medicine and cellular longevity, 2014, Volume: 2014

    Topics: Animals; Arginine; Caloric Restriction; Female; Hypertension; In Vitro Techniques; Kidney; Male; Mel

2014
Asymmetric dimethylarginine is associated with high-sensitivity C-reactive protein and early carotid atherosclerosis in women with previous gestational diabetes mellitus.
    Endocrine, 2015, Volume: 48, Issue:2

    Topics: Adult; Arginine; C-Reactive Protein; Carotid Artery Diseases; Carotid Intima-Media Thickness; Diabet

2015
First-Trimester Maternal Serum Levels of sFLT1, PGF and ADMA Predict Preeclampsia.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Adult; Area Under Curve; Arginine; Blood Pressure; Case-Control Studies; Demography; Female; Follow-

2015
Serial determinations of asymmetric dimethylarginine and homocysteine during pregnancy to predict pre-eclampsia: a longitudinal study.
    BJOG : an international journal of obstetrics and gynaecology, 2015, Volume: 122, Issue:12

    Topics: Adult; Arginine; Biomarkers; Body Mass Index; Female; Folic Acid; Follow-Up Studies; Homocysteine; H

2015
[Interactions between markers of endothelial damage (homocysteine and asymmetric dimethylarginine) and antioxidants and B-vitamins in preeclamptic women].
    Ginecologia y obstetricia de Mexico, 2015, Volume: 83, Issue:6

    Topics: Adolescent; Adult; Antioxidants; Arginine; Biomarkers; Cross-Sectional Studies; Female; Homocysteine

2015
Intercellular Adhesion Molecule and Endogenous NOS Inhibitor: Asymmetric Dimethylarginine in Pregnant Women with Gestational Diabetes Mellitus.
    Journal of diabetes research, 2016, Volume: 2016

    Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Diabetes, Gestational; Enzyme-Linked Immunosorben

2016
N-Acetylcysteine Prevents Programmed Hypertension in Male Rat Offspring Born to Suramin-Treated Mothers.
    Biology of reproduction, 2016, Volume: 95, Issue:1

    Topics: Acetylcysteine; Animals; Arginine; Blood Pressure; Female; Fetal Development; Hydrogen Sulfide; Hype

2016
Endothelin 1, ADMA and SDMA in pregnancies with obstetric and thrombotic antiphospholipid syndrome.
    Journal of reproductive immunology, 2016, Volume: 116

    Topics: Adult; Antiphospholipid Syndrome; Arginine; Chronic Disease; Endothelin-1; Endothelium, Vascular; Fe

2016
Prediction of pre-eclampsia combining NGAL and other biochemical markers with Doppler in the first and/or second trimester of pregnancy. A pilot study.
    European journal of obstetrics, gynecology, and reproductive biology, 2016, Volume: 205

    Topics: Adult; Arginine; Biomarkers; Female; Humans; Lipocalin-2; Matrix Metalloproteinase 9; Pilot Projects

2016
Circulating asymmetric dimethylarginine, endothelin-1 and cell adhesion molecules in women with gestational diabetes.
    Acta diabetologica, 2009, Volume: 46, Issue:4

    Topics: Adult; Arginine; Blood Glucose; Case-Control Studies; Diabetes, Gestational; Endothelin-1; Female; H

2009
Maternal serum ADMA is not associated with proinflammatory cytokines or C-reactive protein during normal pregnancy.
    Cytokine, 2009, Volume: 46, Issue:2

    Topics: Adult; Arginine; Biomarkers; C-Reactive Protein; Creatinine; Cytokines; Enzyme Inhibitors; Female; G

2009
[Relationship between changes of endogenous nitric oxide synthase inhibitor and hydrolase and initiation of pre-eclampsia].
    Zhonghua fu chan ke za zhi, 2009, Volume: 44, Issue:4

    Topics: Adult; Amidohydrolases; Arginine; Chromatography, High Pressure Liquid; Female; Humans; Nitric Oxide

2009
Asymmetric dimethylarginine in the maternal and fetal circulation in preeclampsia.
    Pediatric research, 2009, Volume: 66, Issue:4

    Topics: Adult; Arginine; Female; Fetus; Humans; Infant, Newborn; Maternal-Fetal Exchange; Nitric Oxide; Pre-

2009
Nested case-control study of one-carbon metabolites in mid-pregnancy and risks of cleft lip with and without cleft palate.
    Pediatric research, 2009, Volume: 66, Issue:5

    Topics: Adult; Arginine; Carbon; Case-Control Studies; Cleft Lip; Cleft Palate; Dietary Supplements; Female;

2009
Association of homocysteine, asymmetric dimethylarginine, and nitric oxide with preeclampsia.
    Archives of gynecology and obstetrics, 2010, Volume: 282, Issue:4

    Topics: Arginine; Biomarkers; Case-Control Studies; Chromatography, Liquid; Endothelium-Dependent Relaxing F

2010
Interethnic differences in ADMA concentrations and negative association with nitric oxide formation in preeclampsia.
    Clinica chimica acta; international journal of clinical chemistry, 2010, Oct-09, Volume: 411, Issue:19-20

    Topics: Adult; Arginine; Biomarkers; Black People; Case-Control Studies; Ethnicity; Female; Humans; Nitric O

2010
Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and plasma concentrations of asymmetric dimethylarginine in Turkish pre-eclamptic women without fetal growth retardation.
    The journal of obstetrics and gynaecology research, 2010, Volume: 36, Issue:3

    Topics: Adult; Analysis of Variance; Arginine; Chromatography, High Pressure Liquid; Female; Fetal Growth Re

2010
Asymmetric dimethylarginine concentrations are elevated in women with gestational diabetes.
    Endocrine, 2010, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Arginine; C-Reactive Protein; Diabetes, Gestational; Female; Homocysteine; Humans

2010
Asymmetric dimethylarginine in ELBW newborns exposed to chorioamnionitis.
    Early human development, 2011, Volume: 87, Issue:2

    Topics: Arginine; Chorioamnionitis; Female; Gestational Age; Humans; Infant, Extremely Low Birth Weight; Inf

2011
Asymmetric dimethylarginine in normotensive pregnant women with isolated fetal intrauterine growth restriction: a comparison with preeclamptic women with and without intrauterine growth restriction.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2011, Volume: 24, Issue:7

    Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Female; Fetal Growth Retardation; Humans; Pre-Ecl

2011
Asymmetric dimethylarginine level in hyperglycemic gestation.
    Endocrine, 2011, Volume: 40, Issue:2

    Topics: Adult; Arginine; Blood Glucose; Body Mass Index; Case-Control Studies; Chromatography, High Pressure

2011
Levels of asymmetric dimethylarginine throughout normal pregnancy and in pregnancies complicated with preeclampsia or had a small for gestational age baby.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2012, Volume: 25, Issue:8

    Topics: Adult; Arginine; Blood Chemical Analysis; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; F

2012
The role of asymmetric dimethyl arginine and oxidant/antioxidant system in preeclampsia.
    Fetal and pediatric pathology, 2011, Volume: 30, Issue:6

    Topics: Adult; Antioxidants; Arginine; Case-Control Studies; Citrulline; Female; Fetal Blood; Humans; Lipid

2011
Asymmetric dimethylarginine, arginine and homoarginine at 11-13 weeks' gestation and preeclampsia: a case-control study.
    Journal of human hypertension, 2013, Volume: 27, Issue:1

    Topics: Adult; Arginine; Case-Control Studies; Female; Gas Chromatography-Mass Spectrometry; Homoarginine; H

2013
Birth by cesarean section is associated with elevated neonatal plasma levels of dimethylarginines.
    Pediatrics international : official journal of the Japan Pediatric Society, 2012, Volume: 54, Issue:4

    Topics: Arginine; Cesarean Section; Delivery, Obstetric; Female; Humans; Infant, Newborn; Male; Pregnancy

2012
The association between serum asymmetric dimethyl arginine levels and a history of gestational diabetes among healthy women.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2012, Volume: 23, Issue:5

    Topics: Adult; Arginine; Asymptomatic Diseases; Biomarkers; Blood Glucose; Body Mass Index; Cardiovascular D

2012
Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I.
    Free radical biology & medicine, 2012, Jul-15, Volume: 53, Issue:2

    Topics: Acetylcarnitine; Adaptor Proteins, Signal Transducing; Animals; Animals, Newborn; Arginine; Biopteri

2012
The role of homocysteine, asymmetric dimethylarginine and nitric oxide in pre-eclampsia.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2012, Volume: 32, Issue:6

    Topics: Adult; Arginine; Case-Control Studies; Female; Homocysteine; Humans; Nitric Oxide; Pre-Eclampsia; Pr

2012
Nitric oxide and carbon monoxide production and metabolism in preeclampsia.
    Reproductive sciences (Thousand Oaks, Calif.), 2013, Volume: 20, Issue:5

    Topics: Adult; Amidohydrolases; Arginine; Biomarkers; Blotting, Western; Carbon Monoxide; Case-Control Studi

2013
Compensatory feto-placental upregulation of the nitric oxide system during fetal growth restriction.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Adaptation, Physiological; Adult; Arginine; Endothelial Cells; Endothelium, Vascular; Female; Fetal

2012
Feto-placental nitric oxide, asymmetric dimethylarginine and vascular endothelial growth factor (VEGF) levels and VEGF gene polymorphisms in severe preeclampsia.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2013, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Arginine; Case-Control Studies; Female; Fetal Blood; Genetic Predisposition to Di

2013
Differences in the association between maternal serum homocysteine and ADMA levels in women with pregnancies complicated by preeclampsia and/or intrauterine growth restriction.
    Hypertension in pregnancy, 2013, Volume: 32, Issue:1

    Topics: Adult; Arginine; Case-Control Studies; Female; Fetal Growth Retardation; Homocysteine; Humans; Pre-E

2013
Circulating concentrations of asymmetrical dimethyl-L-arginine are increased in women with previous gestational diabetes.
    Diabetologia, 2002, Volume: 45, Issue:10

    Topics: Adult; Arginine; Biomarkers; Body Mass Index; Diabetes, Gestational; Female; Follow-Up Studies; Huma

2002
Asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, in maternal and fetal circulation.
    Journal of the Society for Gynecologic Investigation, 2003, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Arginine; Enzyme Inhibitors; Female; Fetal Blood; Gestational Age; Humans; Labor,

2003
Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia.
    Lancet (London, England), 2003, May-03, Volume: 361, Issue:9368

    Topics: Arginine; Brachial Artery; Endothelium, Vascular; Female; Humans; Placental Circulation; Pre-Eclamps

2003
Plasma concentrations of asymmetric dimethylarginine (ADMA) in Colombian women with pre-eclampsia.
    JAMA, 2004, Feb-18, Volume: 291, Issue:7

    Topics: Adult; Arginine; Case-Control Studies; Colombia; Female; Humans; Pre-Eclampsia; Pregnancy

2004
Dimethylarginine dimethylaminohydrolase overexpression suppresses graft coronary artery disease.
    Circulation, 2005, Sep-13, Volume: 112, Issue:11

    Topics: Amidohydrolases; Animals; Arginine; Coronary Artery Disease; Cytokines; Enzyme Inhibitors; Female; H

2005
Concentrations of homocysteine, related metabolites and asymmetric dimethylarginine in preeclamptic women with poor nutritional status.
    Clinical chemistry and laboratory medicine, 2005, Volume: 43, Issue:10

    Topics: Adult; Arginine; Female; Homocysteine; Humans; Nutritional Status; Pre-Eclampsia; Pregnancy; Time Fa

2005
Plasma asymmetric dimethylarginine concentration during the perinatal period.
    Neonatology, 2007, Volume: 92, Issue:1

    Topics: Adult; Arginine; Blood Circulation; Endothelium, Vascular; Female; Humans; Infant, Newborn; Nitric O

2007
Impaired vascular nitric oxide bioactivity in women with previous gestational diabetes.
    Wiener klinische Wochenschrift, 2007, Volume: 119, Issue:15-16

    Topics: Adult; Arginine; Body Mass Index; Diabetes Mellitus, Type 2; Diabetes, Gestational; Diabetic Angiopa

2007
Elevated asymmetric dimethylarginine concentrations precede clinical preeclampsia, but not pregnancies with small-for-gestational-age infants.
    American journal of obstetrics and gynecology, 2008, Volume: 198, Issue:1

    Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Female; Humans; Infant, Newborn; Infant, Small fo

2008
Determination of asymmetric dimethylarginine, an endogenous nitric oxide synthase inhibitor, in umbilical blood.
    Metabolism: clinical and experimental, 2008, Volume: 57, Issue:2

    Topics: Adolescent; Adult; Arginine; Child; Child, Preschool; Enzyme Inhibitors; Female; Fetal Blood; Humans

2008
First-trimester uterine artery resistance and maternal serum concentration of asymmetric dimethylarginine.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2008, Volume: 31, Issue:2

    Topics: Adult; Arginine; Arteries; Blood Pressure; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Trime

2008
Plasma concentrations of endogenous inhibitor of nitric oxide synthesis in normal pregnancy and pre-eclampsia.
    Lancet (London, England), 1993, Jul-24, Volume: 342, Issue:8865

    Topics: Animals; Arginine; Female; Humans; Hypertension; Nitric Oxide; Pre-Eclampsia; Pregnancy; Pregnancy C

1993
Effect of asymmetric dimethyl arginine on nitric oxide synthase activity in normal and pre-eclamptic placentae.
    Reproduction, fertility, and development, 1995, Volume: 7, Issue:6

    Topics: Arginine; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Nitric Oxide Synthase; Placenta; P

1995
Determination of N(G),N(G)-dimethylarginine in human plasma by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, May-09, Volume: 692, Issue:2

    Topics: Amino Acids; Arginine; Chromatography, High Pressure Liquid; Female; Humans; Pregnancy; Pregnancy Co

1997
Nitric oxide metabolites, cyclic guanosine 3,5 monophosphate and dimethylarginines during and after uncomplicated pregnancies: a longitudinal study.
    European journal of obstetrics, gynecology, and reproductive biology, 1999, Volume: 82, Issue:1

    Topics: Adult; Arginine; Chromatography, High Pressure Liquid; Creatinine; Cyclic GMP; Enzyme Inhibitors; Et

1999
Amniotic fluid nitric oxide metabolites, cyclic guanosine 3',5' monophosphate and dimethylarginine in alloimmunized pregnancies.
    European journal of obstetrics, gynecology, and reproductive biology, 1999, Volume: 85, Issue:2

    Topics: Amniocentesis; Amniotic Fluid; Arginine; Blood Transfusion, Intrauterine; Creatinine; Cyclic GMP; Em

1999
Levels of dimethylarginines and cytokines in mild and severe preeclampsia.
    Acta obstetricia et gynecologica Scandinavica, 2001, Volume: 80, Issue:7

    Topics: Arginine; Blood Pressure; Cytokines; Female; Gestational Age; Humans; Nitric Oxide Synthase; Pre-Ecl

2001