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n(g),n(g')-dimethyl-l-arginine and Peripheral Vascular Diseases

n(g),n(g')-dimethyl-l-arginine has been researched along with Peripheral Vascular Diseases in 8 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Peripheral Vascular Diseases: Pathological processes involving any one of the BLOOD VESSELS in the vasculature outside the HEART.

Research Excerpts

ExcerptRelevanceReference
"We investigated in this double-blind, controlled study whether prolonged intermittent infusion therapy with L-arginine improves the clinical symptoms of patients with intermittent claudication, as compared with the endothelium-independent vasodilator prostaglandin E1, and control patients."9.08Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease. ( Alexander, K; Bode-Böger, SM; Böger, RH; Creutzig, A; Frölich, JC; Thiele, W, 1998)
"Hyperhomocysteinemia is associated with an enhanced risk for cardiovascular disease."7.72Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA. ( Arakawa, N; Bode-Böger, SM; Böger, RH; Hornig, B; Münzel, T; Sydow, K; Tsikas, D, 2004)
"We investigated in this double-blind, controlled study whether prolonged intermittent infusion therapy with L-arginine improves the clinical symptoms of patients with intermittent claudication, as compared with the endothelium-independent vasodilator prostaglandin E1, and control patients."5.08Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease. ( Alexander, K; Bode-Böger, SM; Böger, RH; Creutzig, A; Frölich, JC; Thiele, W, 1998)
"Hyperhomocysteinemia is associated with an enhanced risk for cardiovascular disease."3.72Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA. ( Arakawa, N; Bode-Böger, SM; Böger, RH; Hornig, B; Münzel, T; Sydow, K; Tsikas, D, 2004)
" Mechanisms responsible for endothelial dysfunction in hyperhomocyst(e)inemia may involve impaired bioavailability of NO, possibly secondary to accumulation of the endogenous NO synthase inhibitor asymmetric dimethylarginine (ADMA) and increased oxidative stress."2.71ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins. ( Arakawa, N; Bode-Böger, SM; Böger, RH; Frölich, JC; Hornig, B; Schwedhelm, E; Sydow, K; Tsikas, D, 2003)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's6 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sydow, K2
Schwedhelm, E1
Arakawa, N2
Bode-Böger, SM4
Tsikas, D2
Hornig, B2
Frölich, JC3
Böger, RH4
Stühlinger, MC1
Oka, RK1
Graf, EE1
Schmölzer, I1
Upson, BM1
Kapoor, O1
Szuba, A1
Malinow, MR1
Wascher, TC1
Pachinger, O1
Cooke, JP1
Tsuda, K1
Nishio, I1
Münzel, T1
Mittermayer, F1
Krzyzanowska, K1
Exner, M1
Mlekusch, W1
Amighi, J1
Sabeti, S1
Minar, E1
Müller, M1
Wolzt, M1
Schillinger, M1
Blardi, P1
de Lalla, A1
Pieragalli, D1
De Franco, V1
Meini, S1
Ceccatelli, L1
Auteri, A1
Thiele, W2
Junker, W1
Alexander, K2
Creutzig, A1

Trials

4 trials available for n(g),n(g')-dimethyl-l-arginine and Peripheral Vascular Diseases

ArticleYear
ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins.
    Cardiovascular research, 2003, Volume: 57, Issue:1

    Topics: Aged; Analysis of Variance; Arginine; Arterial Occlusive Diseases; Double-Blind Method; Female; Foli

2003
Endothelial dysfunction induced by hyperhomocyst(e)inemia: role of asymmetric dimethylarginine.
    Circulation, 2003, Aug-26, Volume: 108, Issue:8

    Topics: Adult; Age Factors; Aged; Arginine; Arteriosclerosis; Brachial Artery; Endothelium, Vascular; Female

2003
Effect of iloprost on plasma asymmetric dimethylarginine and plasma and platelet serotonin in patients with peripheral arterial occlusive disease.
    Prostaglandins & other lipid mediators, 2006, Volume: 80, Issue:3-4

    Topics: Aged; Aged, 80 and over; Arginine; Arterial Occlusive Diseases; Blood Platelets; Blood Pressure; Dia

2006
Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease.
    Journal of the American College of Cardiology, 1998, Volume: 32, Issue:5

    Topics: Aged; Aged, 80 and over; Alprostadil; Arginine; Arterial Occlusive Diseases; Blood Flow Velocity; Ch

1998

Other Studies

4 other studies available for n(g),n(g')-dimethyl-l-arginine and Peripheral Vascular Diseases

ArticleYear
Asymmetric dimethylarginine and circulatory disorders in postmenopausal women.
    Circulation, 2004, Feb-10, Volume: 109, Issue:5

    Topics: Aged; Arginine; Endothelium, Vascular; Estrogen Replacement Therapy; Female; Humans; Middle Aged; Pe

2004
Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA.
    Vascular medicine (London, England), 2004, Volume: 9, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Arterial Occlusive Diseases; Chronic Disease; Endothelium,

2004
Asymmetric dimethylarginine predicts major adverse cardiovascular events in patients with advanced peripheral artery disease.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:11

    Topics: Aged; Arginine; Arteries; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Cohort Stud

2006
Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease.
    Circulation, 1997, Apr-15, Volume: 95, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Arterial Occlusive Diseases; Cyclic GMP; Disease Pr

1997