n(g),n(g')-dimethyl-l-arginine has been researched along with Myocardial Ischemia in 11 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral administration of matrine (200, 100 and 50 mg/kg) significantly attenuated isoproterenol-induced cardiac necrosis and left ventricular dysfunction." | 3.78 | Regulation of endothelial nitric oxide synthase and asymmetric dimethylarginine by matrine attenuates isoproterenol-induced acute myocardial injury in rats. ( Dai, G; Deng, N; Guo, Y; Li, X; Wang, X; Wu, Y; Xu, Q; Zheng, P, 2012) |
| " However, poor polyphenol bioavailability and extensive metabolization restrict their applicability." | 2.72 | Increasing the Power of Polyphenols through Nanoencapsulation for Adjuvant Therapy against Cardiovascular Diseases. ( Baião, DDS; da Silva, DVT; Paschoalin, VMF; Trindade, LR, 2021) |
| " Abnormalities in coronary microvascular function result from increased microvascular resistances and impaired endothelial release of vasoactive substances, especially in production and bioavailability of endothelium derived NO." | 2.47 | Peripheral hemorheological and vascular correlates of coronary blood flow. ( Damaske, A; Fasola, F; Fineschi, M; Forconi, S; Gori, T; Jabs, A; Munzel, T; Muxel, S; Orphal, D; Parker, JD; Radmacher, MC; Schaefer, S; Wild, P, 2011) |
| " Among patients with ischemic heart disease, low progenitor cell bioavailability and kidney dysfunction are emerging as strong predictors of death and recurrent cardiovascular events." | 1.35 | Asymmetric dimethylarginine and impaired cardiovascular healing. ( Andreotti, F; Coluzzi, G; Marzo, F; Santucci, E, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Burger, AL | 1 |
| Stojkovic, S | 1 |
| Diedrich, A | 1 |
| Demyanets, S | 1 |
| Wojta, J | 1 |
| Pezawas, T | 1 |
| Trindade, LR | 1 |
| da Silva, DVT | 1 |
| Baião, DDS | 1 |
| Paschoalin, VMF | 1 |
| Zhang, P | 1 |
| Fassett, JT | 1 |
| Zhu, G | 1 |
| Li, J | 1 |
| Hu, X | 1 |
| Xu, X | 1 |
| Chen, Y | 1 |
| Bache, RJ | 1 |
| Damaske, A | 1 |
| Muxel, S | 1 |
| Fasola, F | 1 |
| Radmacher, MC | 1 |
| Schaefer, S | 1 |
| Jabs, A | 1 |
| Orphal, D | 1 |
| Wild, P | 1 |
| Parker, JD | 1 |
| Fineschi, M | 1 |
| Munzel, T | 1 |
| Forconi, S | 1 |
| Gori, T | 1 |
| Li, X | 1 |
| Wang, X | 1 |
| Guo, Y | 1 |
| Deng, N | 1 |
| Zheng, P | 1 |
| Xu, Q | 1 |
| Wu, Y | 1 |
| Dai, G | 1 |
| Hsu, CP | 1 |
| Lin, SJ | 1 |
| Chung, MY | 1 |
| Lu, TM | 1 |
| Anderssohn, M | 1 |
| Rosenberg, M | 1 |
| Schwedhelm, E | 1 |
| Zugck, C | 1 |
| Lutz, M | 1 |
| Lüneburg, N | 1 |
| Frey, N | 1 |
| Böger, RH | 1 |
| Jonasson, TF | 1 |
| Hedner, T | 1 |
| Hultberg, B | 1 |
| Ohlin, H | 1 |
| Stühlinger, MC | 1 |
| Conci, E | 1 |
| Haubner, BJ | 1 |
| Stocker, EM | 1 |
| Schwaighofer, J | 1 |
| Cooke, JP | 2 |
| Tsao, PS | 1 |
| Pachinger, O | 1 |
| Metzler, B | 1 |
| Coluzzi, G | 1 |
| Santucci, E | 1 |
| Marzo, F | 1 |
| Andreotti, F | 1 |
| Losordo, DW | 1 |
2 reviews available for n(g),n(g')-dimethyl-l-arginine and Myocardial Ischemia
| Article | Year |
|---|---|
Increasing the Power of Polyphenols through Nanoencapsulation for Adjuvant Therapy against Cardiovascular Diseases.
Topics: Antioxidant Response Elements; Antioxidants; Arginine; Cardiotonic Agents; Diabetes Mellitus; Drug C | 2021 |
Peripheral hemorheological and vascular correlates of coronary blood flow.
Topics: Arginine; Blood Flow Velocity; Chest Pain; Coronary Circulation; Diagnosis, Differential; Endotheliu | 2011 |
1 trial available for n(g),n(g')-dimethyl-l-arginine and Myocardial Ischemia
| Article | Year |
|---|---|
Hyperhomocysteinaemia is not associated with increased levels of asymmetric dimethylarginine in patients with ischaemic heart disease.
Topics: Adult; Arginine; Female; Folic Acid; Humans; Hyperhomocysteinemia; Male; Middle Aged; Myocardial Isc | 2003 |
8 other studies available for n(g),n(g')-dimethyl-l-arginine and Myocardial Ischemia
| Article | Year |
|---|---|
Elevated plasma levels of asymmetric dimethylarginine and the risk for arrhythmic death in ischemic and non-ischemic, dilated cardiomyopathy - A prospective, controlled long-term study.
Topics: Aged; Arginine; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Case-Control Studies; Female; Heart A | 2020 |
Repetitive ischemia increases myocardial dimethylarginine dimethylaminohydrolase 1 expression.
Topics: Amidohydrolases; Animals; Arginine; Cell Hypoxia; Cells, Cultured; Collateral Circulation; Coronary | 2017 |
Regulation of endothelial nitric oxide synthase and asymmetric dimethylarginine by matrine attenuates isoproterenol-induced acute myocardial injury in rats.
Topics: Alkaloids; Amidohydrolases; Animals; Arginine; Catechol O-Methyltransferase; Glycogen Synthase Kinas | 2012 |
Asymmetric dimethylarginine predicts clinical outcomes in ischemic chronic heart failure.
Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Chi-Square Distribution; Chromatography, High Pressur | 2012 |
The L-Arginine-asymmetric dimethylarginine ratio is an independent predictor of mortality in dilated cardiomyopathy.
Topics: Arginine; Biomarkers; Cardiomyopathies; Cardiomyopathy, Dilated; Chromatography, Liquid; Creatinine; | 2012 |
Asymmetric dimethyl L-arginine (ADMA) is a critical regulator of myocardial reperfusion injury.
Topics: Amidohydrolases; Animals; Arginine; Blotting, Western; Endothelium, Vascular; Immunohistochemistry; | 2007 |
Asymmetric dimethylarginine and impaired cardiovascular healing.
Topics: Apoptosis; Arginine; Cardiovascular Diseases; Humans; Kidney Diseases; Myocardial Ischemia; Nitric O | 2009 |
Nitric oxide and angiogenesis.
Topics: Angiogenesis Inhibitors; Angiostatins; Animals; Arginine; Arteriosclerosis; Coronary Circulation; Do | 2002 |