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n(g),n(g')-dimethyl-l-arginine and MODS

n(g),n(g')-dimethyl-l-arginine has been researched along with MODS in 11 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Research Excerpts

ExcerptRelevanceReference
"L-arginine and ADMA levels were higher in neonates with sepsis compared to controls (p = 0."9.20Asymmetric dimethylarginine and L-arginine levels in neonatal sepsis and septic shock. ( Aydemir, O; Bas, AY; Demirel, N; Ozcan, B; Yucel, H, 2015)
"Impaired endothelial and microvascular function due to decreased endothelial NO bioavailability is a potential mechanism linking increased plasma ADMA with organ failure and death in sepsis."5.37Asymmetric dimethylarginine, endothelial nitric oxide bioavailability and mortality in sepsis. ( Anstey, NM; Celermajer, DS; Darcy, CJ; Davis, JS; Jones, C; McNeil, YR; Stephens, DP; Yeo, TW, 2011)
"Development of multiple organ failure is the most complex problem in critically ill patients, and is associated with a high mortality."5.32The asymmetrical dimethylarginine (ADMA)-multiple organ failure hypothesis. ( Nijveldt, RJ; Teerlink, T; van Leeuwen, PA, 2003)
"L-arginine and ADMA levels were higher in neonates with sepsis compared to controls (p = 0."5.20Asymmetric dimethylarginine and L-arginine levels in neonatal sepsis and septic shock. ( Aydemir, O; Bas, AY; Demirel, N; Ozcan, B; Yucel, H, 2015)
"Serum concentrations of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, may contribute to endothelial dysfunction and organ failure in sepsis."3.79Elevated asymmetric dimethylarginine levels predict short- and long-term mortality risk in critically ill patients. ( Bruensing, J; Buendgens, L; Dückers, H; Koch, A; Kunze, J; Luedde, T; Matthes, M; Tacke, F; Trautwein, C; Weiskirchen, R, 2013)
"Dysfunctions of the L-arginine (L-arg)/nitric-oxide (NO) pathway are suspected to be important for the pathogenesis of multiple organ dysfunction syndrome (MODS) in septic shock."3.78L-arginine and asymmetric dimethylarginine are early predictors for survival in septic patients with acute liver failure. ( Bierhaus, A; Brenner, T; Bruckner, T; Fleming, TH; Hofer, S; Krauser, U; Martin, E; Mieth, M; Nawroth, PP; Rosenhagen, C; Weigand, MA, 2012)
"Impaired endothelial and microvascular function due to decreased endothelial NO bioavailability is a potential mechanism linking increased plasma ADMA with organ failure and death in sepsis."1.37Asymmetric dimethylarginine, endothelial nitric oxide bioavailability and mortality in sepsis. ( Anstey, NM; Celermajer, DS; Darcy, CJ; Davis, JS; Jones, C; McNeil, YR; Stephens, DP; Yeo, TW, 2011)
"Development of multiple organ failure is the most complex problem in critically ill patients, and is associated with a high mortality."1.32The asymmetrical dimethylarginine (ADMA)-multiple organ failure hypothesis. ( Nijveldt, RJ; Teerlink, T; van Leeuwen, PA, 2003)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's7 (63.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Koch, A1
Weiskirchen, R1
Kunze, J1
Dückers, H1
Bruensing, J1
Buendgens, L1
Matthes, M1
Luedde, T1
Trautwein, C1
Tacke, F1
Sheen, JM1
Chen, YC1
Tain, YL1
Huang, LT1
Aydemir, O1
Ozcan, B1
Yucel, H1
Bas, AY1
Demirel, N1
Ferrigno, A1
Di Pasqua, LG1
Berardo, C1
Richelmi, P1
Vairetti, M1
Davis, JS1
Darcy, CJ1
Yeo, TW1
Jones, C1
McNeil, YR1
Stephens, DP1
Celermajer, DS1
Anstey, NM1
Visser, M1
Vermeulen, MA1
Richir, MC1
Teerlink, T4
Houdijk, AP1
Kostense, PJ1
Wisselink, W1
de Mol, BA1
van Leeuwen, PA4
Oudemans-van Straaten, HM1
Brenner, T1
Fleming, TH1
Rosenhagen, C1
Krauser, U1
Mieth, M1
Bruckner, T1
Martin, E1
Nawroth, PP1
Weigand, MA1
Bierhaus, A1
Hofer, S1
Nijveldt, RJ3
Van Der Hoven, B1
Siroen, MP2
Kuik, DJ1
Rauwerda, JA1
Cynober, L1

Reviews

3 reviews available for n(g),n(g')-dimethyl-l-arginine and MODS

ArticleYear
Increased circulatory asymmetric dimethylarginine and multiple organ failure: bile duct ligation in rat as a model.
    International journal of molecular sciences, 2014, Mar-05, Volume: 15, Issue:3

    Topics: Animals; Arginine; Bile Ducts; Disease Models, Animal; Fibrosis; Ligation; Liver; Liver Cirrhosis; M

2014
Liver plays a central role in asymmetric dimethylarginine-mediated organ injury.
    World journal of gastroenterology, 2015, May-07, Volume: 21, Issue:17

    Topics: Animals; Arginine; Biomarkers; Critical Illness; Humans; Liver; Liver Diseases; Multiple Organ Failu

2015
Elimination of asymmetric dimethylarginine by the kidney and the liver: a link to the development of multiple organ failure?
    The Journal of nutrition, 2004, Volume: 134, Issue:10 Suppl

    Topics: Animals; Arginine; Enzyme Inhibitors; Humans; Kidney; Liver; Multiple Organ Failure; Nitric Oxide Sy

2004

Trials

1 trial available for n(g),n(g')-dimethyl-l-arginine and MODS

ArticleYear
Asymmetric dimethylarginine and L-arginine levels in neonatal sepsis and septic shock.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2015, Volume: 28, Issue:8

    Topics: Arginine; Biomarkers; Case-Control Studies; Female; Humans; Infant, Newborn; Male; Multiple Organ Fa

2015

Other Studies

7 other studies available for n(g),n(g')-dimethyl-l-arginine and MODS

ArticleYear
Elevated asymmetric dimethylarginine levels predict short- and long-term mortality risk in critically ill patients.
    Journal of critical care, 2013, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Case-Control Studies; Critical Ill

2013
Asymmetric dimethylarginine, endothelial nitric oxide bioavailability and mortality in sepsis.
    PloS one, 2011, Feb-18, Volume: 6, Issue:2

    Topics: Adult; Aged; Arginine; Biological Availability; Case-Control Studies; Endothelium, Vascular; Female;

2011
Imbalance of arginine and asymmetric dimethylarginine is associated with markers of circulatory failure, organ failure and mortality in shock patients.
    The British journal of nutrition, 2012, Volume: 107, Issue:10

    Topics: Aged; Area Under Curve; Arginine; Biomarkers; Blood Coagulation; Blood Glucose; Carbonates; Creatine

2012
L-arginine and asymmetric dimethylarginine are early predictors for survival in septic patients with acute liver failure.
    Mediators of inflammation, 2012, Volume: 2012

    Topics: Aged; Arginine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Liver Failure, Acute; Male; Middl

2012
Asymmetrical dimethylarginine (ADMA) in critically ill patients: high plasma ADMA concentration is an independent risk factor of ICU mortality.
    Clinical nutrition (Edinburgh, Scotland), 2003, Volume: 22, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Arginine; Critical Illness; Cross-Sectional Studies; Enzyme Inhib

2003
The asymmetrical dimethylarginine (ADMA)-multiple organ failure hypothesis.
    Clinical nutrition (Edinburgh, Scotland), 2003, Volume: 22, Issue:1

    Topics: Arginine; Critical Illness; Enzyme Inhibitors; Humans; Liver; Multiple Organ Failure; Nitric Oxide

2003
Asymmetrical dimethylarginine and multiple organ failure.
    Clinical nutrition (Edinburgh, Scotland), 2003, Volume: 22, Issue:5

    Topics: Animals; Arginine; Enzyme Inhibitors; Liver; Multiple Organ Failure; Nitric Oxide; Nitric Oxide Synt

2003