n(g),n(g')-dimethyl-l-arginine has been researched along with MELAS Syndrome in 1 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
MELAS Syndrome: A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Based on the hypothesis that mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS) are caused by impaired vasodilation in an intracerebral artery, the authors evaluated the effects of administering l-arginine, a nitric oxide precursor." | 9.11 | L-arginine improves the symptoms of strokelike episodes in MELAS. ( Akita, Y; Fujimoto, S; Koga, Y; Matsuishi, T; Nishioka, J; Povalko, N; Tanabe, Y; Yatsuga, S, 2005) |
| "Based on the hypothesis that mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS) are caused by impaired vasodilation in an intracerebral artery, the authors evaluated the effects of administering l-arginine, a nitric oxide precursor." | 5.11 | L-arginine improves the symptoms of strokelike episodes in MELAS. ( Akita, Y; Fujimoto, S; Koga, Y; Matsuishi, T; Nishioka, J; Povalko, N; Tanabe, Y; Yatsuga, S, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koga, Y | 1 |
| Akita, Y | 1 |
| Nishioka, J | 1 |
| Yatsuga, S | 1 |
| Povalko, N | 1 |
| Tanabe, Y | 1 |
| Fujimoto, S | 1 |
| Matsuishi, T | 1 |
1 trial available for n(g),n(g')-dimethyl-l-arginine and MELAS Syndrome
| Article | Year |
|---|---|
L-arginine improves the symptoms of strokelike episodes in MELAS.
Topics: Administration, Oral; Adolescent; Adult; Amino Acids; Arginine; Cerebral Arteries; Child; Child, Pre | 2005 |