n(g),n(g')-dimethyl-l-arginine has been researched along with Left Ventricular Hypertrophy in 14 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
| Excerpt | Relevance | Reference |
|---|---|---|
| " Asymmetrical dimethylarginine (ADMA), the most potent endogenous NO synthase inhibitor, is emerging as an important cardiovascular risk factor in patients with arterial hypertension and LVH, and dimethylarginine dimethylaminohydrolase (DDAH) is the mechanism that most frequently leads to accumulation of ADMA (plasma ADMA is cleared in small part by renal excretion, although the bulk of ADMA is degraded by DDAH)." | 7.83 | Does the ADMA/DDAH/NO pathway modulate early regression of left ventricular hypertrophy with esmolol? ( Delgado-Baeza, E; Quintana-Villamandos, B, 2016) |
| " In contrast, cDDAH1 KO mice exposed to TAC showed no increase in LV DDAH1 expression, slightly increased LV tissue ADMA levels, no increase in plasma ADMA, but significantly exacerbated LV hypertrophy, fibrosis, nitrotyrosine production, and LV dysfunction." | 3.85 | Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction. ( Atzler, D; Böger, RH; Chen, P; Chen, Y; Fassett, J; Guo, H; Hu, X; Kwak, D; Liu, X; Lu, Z; Schwedhelm, E; Wang, H; Xu, X; Yue, W; Zhang, P, 2017) |
| " Asymmetrical dimethylarginine (ADMA), the most potent endogenous NO synthase inhibitor, is emerging as an important cardiovascular risk factor in patients with arterial hypertension and LVH, and dimethylarginine dimethylaminohydrolase (DDAH) is the mechanism that most frequently leads to accumulation of ADMA (plasma ADMA is cleared in small part by renal excretion, although the bulk of ADMA is degraded by DDAH)." | 3.83 | Does the ADMA/DDAH/NO pathway modulate early regression of left ventricular hypertrophy with esmolol? ( Delgado-Baeza, E; Quintana-Villamandos, B, 2016) |
| " Patients with metabolic syndrome (MS) had lower activity of gluthatione peroxidase, higher asymmetric dimethyloarginine (ADMA) and oxidized LDL cholesterol (oxyLDL) in comparison to patients without MS." | 3.78 | Oxidative stress in hypertensive children before and after 1 year of antihypertensive therapy. ( Janas, R; Litwin, M; Niemirska, A; Płudowski, P; Skorupa, E; Sladowska-Kozłowska, J; Wawer, ZT; Wierzbicka, A, 2012) |
| " We found that mild hypertension, increased plasma levels of creatinine, inorganic phosphate, asymmetric dimethylarginine (ADMA), and parathyroid hormone (PTH) were observed in the present SNx rats without LVH." | 3.77 | Left ventricular hypertrophy is associated with inflammation in sodium loaded subtotal nephrectomized rats. ( Aizawa, K; Ishizuka, N; Iwabuchi, S; Kitamura, H; Moriguchi, Y; Nishimura, T; Serizawa, K; Tashiro, Y; Yogo, K; Yorozu, K, 2011) |
| " We hypothesized that changes in serum asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, and concomitant insulin resistance may be underlying factors connecting the two pathologic alterations." | 3.72 | Plasma asymmetric dimethylarginine and coronary and peripheral endothelial dysfunction in hypertensive patients. ( Fujii, H; Hiuge, A; Horio, T; Kamide, K; Kawano, Y; Nakatani, S; Ogihara, T; Rakugi, H; Takiuchi, S, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 10 (71.43) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Leffler, KE | 1 |
| Abdel-Rahman, AA | 1 |
| Xu, X | 1 |
| Zhang, P | 1 |
| Kwak, D | 1 |
| Fassett, J | 1 |
| Yue, W | 1 |
| Atzler, D | 1 |
| Hu, X | 1 |
| Liu, X | 1 |
| Wang, H | 1 |
| Lu, Z | 1 |
| Guo, H | 1 |
| Schwedhelm, E | 1 |
| Böger, RH | 1 |
| Chen, P | 1 |
| Chen, Y | 1 |
| El Shahawy, Y | 1 |
| Soliman, Y | 1 |
| Rifaie, A | 1 |
| Shenawy, H | 1 |
| Behairy, M | 1 |
| Mady, G | 1 |
| Bartnicki, P | 1 |
| Kowalczyk, M | 1 |
| Franczyk-Skóra, B | 1 |
| Baj, Z | 1 |
| Rysz, J | 1 |
| Quintana-Villamandos, B | 1 |
| Delgado-Baeza, E | 1 |
| Ebinç, FA | 1 |
| Erten, Y | 1 |
| Ebinç, H | 1 |
| Paşaoğlu, H | 1 |
| Demirtaş, C | 1 |
| Taçoy, G | 1 |
| Mutluay, R | 1 |
| Koç, E | 1 |
| Derici, U | 1 |
| Reis, KA | 1 |
| Bali, M | 1 |
| Arinsoy, T | 1 |
| Sindel, S | 1 |
| Shi, B | 1 |
| Ni, Z | 1 |
| Zhou, W | 1 |
| Yu, Z | 1 |
| Gu, L | 1 |
| Mou, S | 1 |
| Fang, W | 1 |
| Wang, Q | 1 |
| Cao, L | 1 |
| Yan, Y | 1 |
| Qian, J | 1 |
| Moriguchi, Y | 1 |
| Yogo, K | 1 |
| Aizawa, K | 1 |
| Serizawa, K | 1 |
| Tashiro, Y | 1 |
| Yorozu, K | 1 |
| Ishizuka, N | 1 |
| Iwabuchi, S | 1 |
| Kitamura, H | 1 |
| Nishimura, T | 1 |
| Grassi, G | 1 |
| Seravalle, G | 1 |
| Ghiadoni, L | 1 |
| Tripepi, G | 2 |
| Bruno, RM | 1 |
| Mancia, G | 1 |
| Zoccali, C | 2 |
| Napora, M | 1 |
| Graczykowska, A | 1 |
| Próchniewska, K | 1 |
| Zdrojewski, Z | 1 |
| Całka, A | 1 |
| Górny, J | 1 |
| Stompór, T | 1 |
| Sladowska-Kozłowska, J | 1 |
| Litwin, M | 1 |
| Niemirska, A | 1 |
| Płudowski, P | 1 |
| Wierzbicka, A | 1 |
| Skorupa, E | 1 |
| Wawer, ZT | 1 |
| Janas, R | 1 |
| Li, H | 1 |
| Wang, S | 1 |
| Takiuchi, S | 1 |
| Fujii, H | 1 |
| Kamide, K | 1 |
| Horio, T | 1 |
| Nakatani, S | 1 |
| Hiuge, A | 1 |
| Rakugi, H | 1 |
| Ogihara, T | 1 |
| Kawano, Y | 1 |
| Mallamaci, F | 1 |
| Maas, R | 1 |
| Benedetto, FA | 1 |
| Malatino, LS | 1 |
| Cataliotti, A | 1 |
| Bellanuova, I | 1 |
| Böger, R | 1 |
1 trial available for n(g),n(g')-dimethyl-l-arginine and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Organic nitrates favor regression of left ventricular hypertrophy in hypertensive patients on chronic peritoneal dialysis.
Topics: Adult; Aged; Antihypertensive Agents; Arginine; Blood Pressure; Female; Humans; Hypertension; Hypert | 2013 |
13 other studies available for n(g),n(g')-dimethyl-l-arginine and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Restoration of Adiponectin-Connexin43 Signaling Mitigates Myocardial Inflammation and Dysfunction in Diabetic Female Rats.
Topics: Adiponectin; Animals; Arginine; Connexin 43; Diabetes Mellitus, Experimental; Diabetes Mellitus, Typ | 2020 |
Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction.
Topics: Amidohydrolases; Animals; Arginine; Atrial Natriuretic Factor; Disease Models, Animal; Fibrosis; Gen | 2017 |
Relationship between asymmetric dimethylarginine plasma level and left ventricular mass in hemodialysis patients.
Topics: Adult; Arginine; Female; Glomerular Filtration Rate; Humans; Hypertension; Hypertrophy, Left Ventric | 2015 |
Evaluation of Endothelial (dys)Function, Left Ventricular Structure and Function in Patients with Chronic Kidney Disease.
Topics: Aged; Arginine; Biomarkers; Case-Control Studies; Echocardiography, Doppler; Endothelium, Vascular; | 2016 |
Does the ADMA/DDAH/NO pathway modulate early regression of left ventricular hypertrophy with esmolol?
Topics: Adrenergic beta-1 Receptor Antagonists; Amidohydrolases; Animals; Antihypertensive Agents; Arginine; | 2016 |
The relationship among asymmetric dimethylarginine (ADMA) levels, residual renal function, and left ventricular hypertrophy in continuous ambulatory peritoneal dialysis patients.
Topics: Adult; Analysis of Variance; Arginine; Biomarkers; Case-Control Studies; Creatinine; Female; Follow- | 2008 |
Circulating levels of asymmetric dimethylarginine are an independent risk factor for left ventricular hypertrophy and predict cardiovascular events in pre-dialysis patients with chronic kidney disease.
Topics: Adult; Arginine; Female; Follow-Up Studies; Humans; Hypertrophy, Left Ventricular; Kaplan-Meier Esti | 2010 |
Left ventricular hypertrophy is associated with inflammation in sodium loaded subtotal nephrectomized rats.
Topics: Animals; Arginine; Creatinine; Disease Models, Animal; Fibrosis; Hypertension; Hypertrophy, Left Ven | 2011 |
Sympathetic nerve traffic and asymmetric dimethylarginine in chronic kidney disease.
Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Chronic Disease; Cross-Sectional Studies; Disease Pro | 2011 |
Relationship between serum asymmetric dimethylarginine and left ventricular structure and function in patients with end‑stage renal disease treated with hemodialysis.
Topics: Arginine; Biomarkers; Echocardiography; Female; Heart Ventricles; Humans; Hypertrophy, Left Ventricu | 2012 |
Oxidative stress in hypertensive children before and after 1 year of antihypertensive therapy.
Topics: Adiposity; Adolescent; Albuminuria; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; A | 2012 |
Plasma asymmetric dimethylarginine and coronary and peripheral endothelial dysfunction in hypertensive patients.
Topics: Aged; Arginine; Coronary Circulation; Echocardiography, Doppler; Endothelium, Vascular; Female; Fore | 2004 |
Left ventricular hypertrophy, cardiac remodeling and asymmetric dimethylarginine (ADMA) in hemodialysis patients.
Topics: Adult; Aged; Arginine; Echocardiography; Endothelium, Vascular; Female; Humans; Hypertrophy, Left Ve | 2002 |