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n(g),n(g')-dimethyl-l-arginine and Left Ventricular Dysfunction

n(g),n(g')-dimethyl-l-arginine has been researched along with Left Ventricular Dysfunction in 15 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Research Excerpts

ExcerptRelevanceReference
"Elevated plasma levels of asymmetric dimethylarginine (ADMA), an endothelial nitric oxide synthase (eNOS) inhibitor, may contribute to endothelial dysfunction in chronic heart failure (CHF)."9.13Effect of atorvastatin on plasma levels of asymmetric dimethylarginine in patients with non-ischaemic heart failure. ( Florkowski, CM; Frampton, CM; George, PM; Scott, RS; Sies, CW; Strey, CH; Young, JM, 2008)
"This prospective study investigated whether plasma asymmetric dimethylarginine (ADMA) concentrations are related to cardiovascular events in patients with acute heart failure."7.74Plasma asymmetric dimethylarginine and cardiovascular events in patients with acute decompensated heart failure. ( Altenberger, J; Dückelmann, C; Haider, DG; Mittermayer, F; Wolzt, M, 2008)
"Asymmetric dimethylarginine plasma levels were significantly higher in pts with appropriate ICD intervention compared with those without any ICD intervention (0."5.37Asymmetric dimethylarginine predicts appropriate implantable cardioverter-defibrillator intervention in patients with left ventricular dysfunction. ( Bode-Böger, SM; Bukowska, A; Ghanem, A; Goette, A; Hammwöhner, M; Klein, HU; Lehmann, HI; Martens-Lobenhoffer, J; Röhl, FW, 2011)
"Elevated plasma levels of asymmetric dimethylarginine (ADMA), an endothelial nitric oxide synthase (eNOS) inhibitor, may contribute to endothelial dysfunction in chronic heart failure (CHF)."5.13Effect of atorvastatin on plasma levels of asymmetric dimethylarginine in patients with non-ischaemic heart failure. ( Florkowski, CM; Frampton, CM; George, PM; Scott, RS; Sies, CW; Strey, CH; Young, JM, 2008)
" In contrast, cDDAH1 KO mice exposed to TAC showed no increase in LV DDAH1 expression, slightly increased LV tissue ADMA levels, no increase in plasma ADMA, but significantly exacerbated LV hypertrophy, fibrosis, nitrotyrosine production, and LV dysfunction."3.85Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction. ( Atzler, D; Böger, RH; Chen, P; Chen, Y; Fassett, J; Guo, H; Hu, X; Kwak, D; Liu, X; Lu, Z; Schwedhelm, E; Wang, H; Xu, X; Yue, W; Zhang, P, 2017)
"This prospective study investigated whether plasma asymmetric dimethylarginine (ADMA) concentrations are related to cardiovascular events in patients with acute heart failure."3.74Plasma asymmetric dimethylarginine and cardiovascular events in patients with acute decompensated heart failure. ( Altenberger, J; Dückelmann, C; Haider, DG; Mittermayer, F; Wolzt, M, 2008)
"Asymmetric dimethylarginine plasma levels were significantly higher in pts with appropriate ICD intervention compared with those without any ICD intervention (0."1.37Asymmetric dimethylarginine predicts appropriate implantable cardioverter-defibrillator intervention in patients with left ventricular dysfunction. ( Bode-Böger, SM; Bukowska, A; Ghanem, A; Goette, A; Hammwöhner, M; Klein, HU; Lehmann, HI; Martens-Lobenhoffer, J; Röhl, FW, 2011)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (33.33)29.6817
2010's8 (53.33)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Leffler, KE1
Abdel-Rahman, AA1
Burger, AL1
Stojkovic, S1
Diedrich, A1
Demyanets, S1
Wojta, J1
Pezawas, T1
Xu, X1
Zhang, P1
Kwak, D1
Fassett, J1
Yue, W1
Atzler, D1
Hu, X1
Liu, X1
Wang, H1
Lu, Z1
Guo, H1
Schwedhelm, E2
Böger, RH2
Chen, P1
Chen, Y1
Pang, P1
Abbott, M1
Abdi, M1
Fucci, QA1
Chauhan, N1
Mistri, M1
Proctor, B1
Chin, M1
Wang, B1
Yin, W1
Lu, TS1
Halim, A1
Lim, K1
Handy, DE1
Loscalzo, J1
Siedlecki, AM1
El Shahawy, Y1
Soliman, Y1
Rifaie, A1
Shenawy, H1
Behairy, M1
Mady, G1
Givvimani, S1
Kundu, S1
Pushpakumar, S1
Doyle, V1
Narayanan, N1
Winchester, LJ1
Veeranki, S1
Metreveli, N1
Tyagi, SC1
Bartnicki, P1
Kowalczyk, M1
Franczyk-Skóra, B1
Baj, Z1
Rysz, J1
Dückelmann, C2
Mittermayer, F2
Haider, DG2
Altenberger, J2
Wolzt, M2
Lieb, W1
Benndorf, RA1
Benjamin, EJ1
Sullivan, LM1
Maas, R2
Xanthakis, V1
Aragam, J1
Schulze, F1
Vasan, RS1
Dimitroulas, T1
Giannakoulas, G1
Papadopoulou, K1
Karvounis, H1
Dimitroula, H1
Koliakos, G1
Karamitsos, T1
Parcharidou, D1
Settas, L1
Lehmann, HI1
Goette, A1
Martens-Lobenhoffer, J1
Hammwöhner, M1
Röhl, FW1
Bukowska, A1
Ghanem, A1
Klein, HU1
Bode-Böger, SM1
Napora, M1
Graczykowska, A1
Próchniewska, K1
Zdrojewski, Z1
Całka, A1
Górny, J1
Stompór, T1
Eichinger, J1
Young, JM1
Strey, CH1
George, PM1
Florkowski, CM1
Sies, CW1
Frampton, CM1
Scott, RS1
Zoccali, C1
Mallamaci, F1
Benedetto, FA1
Tripepi, G1
Malatino, LS1
Cataliotti, A1
Bellanuova, I1
Böger, R1

Trials

1 trial available for n(g),n(g')-dimethyl-l-arginine and Left Ventricular Dysfunction

ArticleYear
Effect of atorvastatin on plasma levels of asymmetric dimethylarginine in patients with non-ischaemic heart failure.
    European journal of heart failure, 2008, Volume: 10, Issue:5

    Topics: Arginine; Atorvastatin; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Heart Failur

2008

Other Studies

14 other studies available for n(g),n(g')-dimethyl-l-arginine and Left Ventricular Dysfunction

ArticleYear
Restoration of Adiponectin-Connexin43 Signaling Mitigates Myocardial Inflammation and Dysfunction in Diabetic Female Rats.
    Journal of cardiovascular pharmacology, 2020, Volume: 75, Issue:3

    Topics: Adiponectin; Animals; Arginine; Connexin 43; Diabetes Mellitus, Experimental; Diabetes Mellitus, Typ

2020
Elevated plasma levels of asymmetric dimethylarginine and the risk for arrhythmic death in ischemic and non-ischemic, dilated cardiomyopathy - A prospective, controlled long-term study.
    Clinical biochemistry, 2020, Volume: 83

    Topics: Aged; Arginine; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Case-Control Studies; Female; Heart A

2020
Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction.
    Basic research in cardiology, 2017, 08-17, Volume: 112, Issue:5

    Topics: Amidohydrolases; Animals; Arginine; Atrial Natriuretic Factor; Disease Models, Animal; Fibrosis; Gen

2017
Pre-clinical model of severe glutathione peroxidase-3 deficiency and chronic kidney disease results in coronary artery thrombosis and depressed left ventricular function.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2018, 06-01, Volume: 33, Issue:6

    Topics: Animals; Arginine; Disease Models, Animal; Glutathione Peroxidase; Heart Diseases; Mice; Mice, Knock

2018
Relationship between asymmetric dimethylarginine plasma level and left ventricular mass in hemodialysis patients.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2015, Volume: 26, Issue:1

    Topics: Adult; Arginine; Female; Glomerular Filtration Rate; Humans; Hypertension; Hypertrophy, Left Ventric

2015
Hyperhomocysteinemia: a missing link to dysfunctional HDL via paraoxanase-1.
    Canadian journal of physiology and pharmacology, 2015, Volume: 93, Issue:9

    Topics: Amidohydrolases; Animals; Arginine; Aryldialkylphosphatase; Atherosclerosis; Blood Pressure; Connexi

2015
Evaluation of Endothelial (dys)Function, Left Ventricular Structure and Function in Patients with Chronic Kidney Disease.
    Current vascular pharmacology, 2016, Volume: 14, Issue:4

    Topics: Aged; Arginine; Biomarkers; Case-Control Studies; Echocardiography, Doppler; Endothelium, Vascular;

2016
Plasma asymmetric dimethylarginine and cardiovascular events in patients with acute decompensated heart failure.
    Translational research : the journal of laboratory and clinical medicine, 2008, Volume: 152, Issue:1

    Topics: Aged; Arginine; Austria; Cohort Studies; Female; Heart Failure; Humans; Male; Middle Aged; Natriuret

2008
Plasma asymmetric dimethylarginine, L-arginine and left ventricular structure and function in a community-based sample.
    Atherosclerosis, 2009, Volume: 204, Issue:1

    Topics: Aged; Arginine; Female; Heart Atria; Heart Ventricles; Humans; Linear Models; Male; Middle Aged; Mul

2009
Early detection of cardiac involvement in systemic sclerosis assessed by tissue-Doppler echocardiography: relationship with neurohormonal activation and endothelial dysfunction.
    The Journal of rheumatology, 2010, Volume: 37, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Arginine; Blood Flow Velocity; Echocardiography, Doppler; Endothe

2010
Asymmetric dimethylarginine predicts appropriate implantable cardioverter-defibrillator intervention in patients with left ventricular dysfunction.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2011, Volume: 13, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Defibrillators, Implantable; Follow-Up Studies

2011
Relationship between serum asymmetric dimethylarginine and left ventricular structure and function in patients with end‑stage renal disease treated with hemodialysis.
    Polskie Archiwum Medycyny Wewnetrznej, 2012, Volume: 122, Issue:5

    Topics: Arginine; Biomarkers; Echocardiography; Female; Heart Ventricles; Humans; Hypertrophy, Left Ventricu

2012
Asymmetric dimethylarginine enhances cardiovascular risk prediction in patients with chronic heart failure.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:9

    Topics: Aged; Arginine; Austria; Biomarkers; Disease-Free Survival; Female; Heart Failure; Humans; Male; Nat

2007
Left ventricular hypertrophy, cardiac remodeling and asymmetric dimethylarginine (ADMA) in hemodialysis patients.
    Kidney international, 2002, Volume: 62, Issue:1

    Topics: Adult; Aged; Arginine; Echocardiography; Endothelium, Vascular; Female; Humans; Hypertrophy, Left Ve

2002