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n(g),n(g')-dimethyl-l-arginine and Ischemia

n(g),n(g')-dimethyl-l-arginine has been researched along with Ischemia in 12 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"The aim of the present study was to establish a rat model of acute ischemic kidney injury by continually occluding the bilateral renal artery and renal veins, as well as to examine the role of asymmetric dimethylarginine (ADMA) in acute lung injury (ALI) induced by acute kidney injury (AKI)."7.81Role of asymmetric dimethylarginine in rat acute lung injury induced by acute ischemic kidney injury. ( Liu, X; Liu, Z; Ma, T, 2015)
"Asymmetric dimethylarginine (ADMA) plays role in the pathogenesis of coronary artery disease and related mortality and morbidity through a number of mechanisms."7.81Asymmetric dimethylarginine is not a good predictor of ischemia using myocardial perfusion scintigraphy. ( Aşik, M; Aslantaş, Y; Bulur, S; Doğan, AS; Erkan, ME; Ilçe, HT; Memişoğullari, R; Uçgun, T; Yildirim, M; Yildiz, N; Yilmaz, A, 2015)
"Primary dysmenorrhea is a common disorder among young women, and uterine ischemia plays an important role in pelvic pain."5.36Increased serum asymmetric dimethylarginine levels in primary dysmenorrhea. ( Akdemir, N; Akdemir, R; Akin, O; Bilir, C; Cinemre, H, 2010)
" In recent years, the emerging new understanding of the NO pathway has shown that an endogenously produced inhibitor of NOS, asymmetric dimethylarginine (ADMA), a host response to infection, may play an important role in the pathophysiology of sepsis as well as organ damage during ischemia-reperfusion."5.22A new perspective on NO pathway in sepsis and ADMA lowering as a potential therapeutic approach. ( Kellum, JA; Lee, Y; Singh, J, 2022)
"The aim of the present study was to establish a rat model of acute ischemic kidney injury by continually occluding the bilateral renal artery and renal veins, as well as to examine the role of asymmetric dimethylarginine (ADMA) in acute lung injury (ALI) induced by acute kidney injury (AKI)."3.81Role of asymmetric dimethylarginine in rat acute lung injury induced by acute ischemic kidney injury. ( Liu, X; Liu, Z; Ma, T, 2015)
"Asymmetric dimethylarginine (ADMA) plays role in the pathogenesis of coronary artery disease and related mortality and morbidity through a number of mechanisms."3.81Asymmetric dimethylarginine is not a good predictor of ischemia using myocardial perfusion scintigraphy. ( Aşik, M; Aslantaş, Y; Bulur, S; Doğan, AS; Erkan, ME; Ilçe, HT; Memişoğullari, R; Uçgun, T; Yildirim, M; Yildiz, N; Yilmaz, A, 2015)
" We examined the hypothesis that HC may inhibit ischemia-induced angiogenesis by inhibition of EDNO in a rat model of unilateral hindlimb ischemia and that oral L-arginine supplementation, a substrate for NO synthase, may prevent HC-related impairment of angiogenesis."3.70Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism. ( Duan, J; Ikeda, H; Imaizumi, T; Katoh, A; Kawata, H; Murohara, T; Sasaki, K; Shintani, S; Yamamoto, N, 2000)
"Primary dysmenorrhea is a common disorder among young women, and uterine ischemia plays an important role in pelvic pain."1.36Increased serum asymmetric dimethylarginine levels in primary dysmenorrhea. ( Akdemir, N; Akdemir, R; Akin, O; Bilir, C; Cinemre, H, 2010)
"Hindlimb ischemia was surgically induced in C57BL/6J mice, apo E-deficient mice, or transgenic mice overexpressing dimethylarginine dimethylaminohydrolase (DDAH)."1.33ADMA regulates angiogenesis: genetic and metabolic evidence. ( Achan, V; Cooke, JP; Heeschen, C; Ho, HK; Jang, JJ; Kimoto, M; Stuehlinger, M; Vallance, P, 2005)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Singh, J1
Lee, Y1
Kellum, JA1
Madaric, J1
Valachovicova, M1
Paulis, L1
Pribojova, J1
Mateova, R1
Sebekova, K1
Postulkova, L1
Madaricova, T1
Bucova, M1
Mistrik, M1
Vulev, I1
Ma, T1
Liu, X1
Liu, Z1
Erkan, ME1
Aşik, M1
Uçgun, T1
Yildiz, N1
Yilmaz, A1
Aslantaş, Y1
Bulur, S1
Ilçe, HT1
Yildirim, M1
Memişoğullari, R1
Doğan, AS1
Kocak, C1
Kocak, FE1
Akcilar, R1
Bayat, Z1
Aras, B1
Metineren, MH1
Yucel, M1
Simsek, H1
Shibata, R1
Ueda, S1
Yamagishi, S1
Kaida, Y1
Matsumoto, Y1
Fukami, K1
Hayashida, A1
Matsuoka, H1
Kato, S1
Kimoto, M3
Okuda, S1
Leypoldt, F1
Choe, CU1
Gelderblom, M1
von Leitner, EC1
Atzler, D1
Schwedhelm, E1
Gerloff, C1
Sydow, K2
Böger, RH1
Magnus, T1
Akdemir, N1
Cinemre, H1
Bilir, C1
Akin, O1
Akdemir, R1
Jacobi, J1
von Degenfeld, G1
Zhang, Y1
Dayoub, H1
Wang, B1
Patterson, AJ1
Blau, HM1
Cooke, JP2
Achan, V1
Ho, HK1
Heeschen, C1
Stuehlinger, M1
Jang, JJ1
Vallance, P1
Duan, J1
Murohara, T1
Ikeda, H1
Katoh, A1
Shintani, S1
Sasaki, K1
Kawata, H1
Yamamoto, N1
Imaizumi, T1
Masuda, H1
Tsujii, T1
Okuno, T1
Kihara, K1
Goto, M1
Azuma, H1

Reviews

1 review available for n(g),n(g')-dimethyl-l-arginine and Ischemia

ArticleYear
A new perspective on NO pathway in sepsis and ADMA lowering as a potential therapeutic approach.
    Critical care (London, England), 2022, 08-12, Volume: 26, Issue:1

    Topics: Animals; Arginine; Humans; Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Sepsis

2022

Trials

1 trial available for n(g),n(g')-dimethyl-l-arginine and Ischemia

ArticleYear
Improvement in asymmetric dimethylarginine and oxidative stress in patients with limb salvage after autologous mononuclear stem cell application for critical limb ischemia.
    Stem cell research & therapy, 2017, 07-12, Volume: 8, Issue:1

    Topics: Aged; Arginine; Autografts; Extremities; Female; Follow-Up Studies; Humans; Ischemia; Leukocytes, Mo

2017

Other Studies

10 other studies available for n(g),n(g')-dimethyl-l-arginine and Ischemia

ArticleYear
Role of asymmetric dimethylarginine in rat acute lung injury induced by acute ischemic kidney injury.
    Molecular medicine reports, 2015, Volume: 12, Issue:2

    Topics: Actins; Acute Kidney Injury; Acute Lung Injury; Animals; Arginine; Enzyme Activation; HSP27 Heat-Sho

2015
Asymmetric dimethylarginine is not a good predictor of ischemia using myocardial perfusion scintigraphy.
    Turkish journal of medical sciences, 2015, Volume: 45, Issue:4

    Topics: Arginine; Coronary Artery Disease; Echocardiography; Female; Humans; Ischemia; Male; Middle Aged; My

2015
Effects of captopril, telmisartan and bardoxolone methyl (CDDO-Me) in ischemia-reperfusion-induced acute kidney injury in rats: an experimental comparative study.
    Clinical and experimental pharmacology & physiology, 2016, Volume: 43, Issue:2

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Antioxidants; Apoptosis; Arginine; Benzimidazole

2016
Involvement of asymmetric dimethylarginine (ADMA) in tubulointerstitial ischaemia in the early phase of diabetic nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:4

    Topics: Adenoviridae; Amidohydrolases; Animals; Arginine; Diabetic Nephropathies; Disease Models, Animal; Ge

2009
Dimethylarginine dimethylaminohydrolase-1 transgenic mice are not protected from ischemic stroke.
    PloS one, 2009, Oct-07, Volume: 4, Issue:10

    Topics: Amidohydrolases; Animals; Arginine; Brain; Endothelium, Vascular; Genotype; Infarction, Middle Cereb

2009
Increased serum asymmetric dimethylarginine levels in primary dysmenorrhea.
    Gynecologic and obstetric investigation, 2010, Volume: 69, Issue:3

    Topics: Adolescent; Adult; Arginine; Biomarkers; Body Mass Index; C-Reactive Protein; Cholesterol, LDL; Coho

2010
Overexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis.
    Circulation, 2005, Mar-22, Volume: 111, Issue:11

    Topics: Amidohydrolases; Animals; Arginine; Enzyme Induction; Female; Hindlimb; Humans; Ischemia; Laser-Dopp

2005
ADMA regulates angiogenesis: genetic and metabolic evidence.
    Vascular medicine (London, England), 2005, Volume: 10, Issue:1

    Topics: Animals; Arginine; Blotting, Western; Disease Models, Animal; Female; Hypercholesterolemia; Ischemia

2005
Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism.
    Circulation, 2000, Nov-07, Volume: 102, Issue:19 Suppl 3

    Topics: Administration, Oral; Animals; Arginine; Body Weight; Cholesterol, Dietary; Collateral Circulation;

2000
Accumulated endogenous NOS inhibitors, decreased NOS activity, and impaired cavernosal relaxation with ischemia.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:6

    Topics: Animals; Arginine; Calcium; Carbachol; Cholinergic Agonists; Cyclic GMP; Disease Models, Animal; Dos

2002