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n(g),n(g')-dimethyl-l-arginine and Intermittent Claudication

n(g),n(g')-dimethyl-l-arginine has been researched along with Intermittent Claudication in 4 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Intermittent Claudication: A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.

Research Excerpts

ExcerptRelevanceReference
"We investigated in this double-blind, controlled study whether prolonged intermittent infusion therapy with L-arginine improves the clinical symptoms of patients with intermittent claudication, as compared with the endothelium-independent vasodilator prostaglandin E1, and control patients."9.08Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease. ( Alexander, K; Bode-Böger, SM; Böger, RH; Creutzig, A; Frölich, JC; Thiele, W, 1998)
"We investigated in this double-blind, controlled study whether prolonged intermittent infusion therapy with L-arginine improves the clinical symptoms of patients with intermittent claudication, as compared with the endothelium-independent vasodilator prostaglandin E1, and control patients."5.08Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease. ( Alexander, K; Bode-Böger, SM; Böger, RH; Creutzig, A; Frölich, JC; Thiele, W, 1998)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderssohn, M1
McLachlan, S1
Lüneburg, N1
Robertson, C1
Schwedhelm, E1
Williamson, RM1
Strachan, MW1
Ajjan, R1
Grant, PJ1
Böger, RH2
Price, JF1
Delaney, CL1
Miller, MD1
Allan, RB1
Spark, JI1
Schlager, O1
Giurgea, A1
Schuhfried, O1
Seidinger, D1
Hammer, A1
Gröger, M1
Fialka-Moser, V1
Gschwandtner, M1
Koppensteiner, R1
Steiner, S1
Bode-Böger, SM1
Thiele, W1
Creutzig, A1
Alexander, K1
Frölich, JC1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Influence of Different Types of Exercise Training on Selected Cardiovascular Parameters in Individuals With Peripheral Arterial Disease[NCT02642276]36 participants (Actual)Interventional2015-06-30Completed
Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in Type 2 Diabetes ( ZQL007)[NCT03883412]Phase 460 participants (Anticipated)Interventional2019-02-28Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for n(g),n(g')-dimethyl-l-arginine and Intermittent Claudication

ArticleYear
The impact of different supervised exercise regimens on endothelial function in patients with intermittent claudication.
    Vascular, 2015, Volume: 23, Issue:6

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Endothelium, Vascular; Exercise Test; Exercise Therap

2015
Exercise training increases endothelial progenitor cells and decreases asymmetric dimethylarginine in peripheral arterial disease: a randomized controlled trial.
    Atherosclerosis, 2011, Volume: 217, Issue:1

    Topics: Aged; Arginine; Cell Movement; Chemokine CXCL12; Endothelial Cells; Exercise; Female; Flow Cytometry

2011
Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease.
    Journal of the American College of Cardiology, 1998, Volume: 32, Issue:5

    Topics: Aged; Aged, 80 and over; Alprostadil; Arginine; Arterial Occlusive Diseases; Blood Flow Velocity; Ch

1998

Other Studies

1 other study available for n(g),n(g')-dimethyl-l-arginine and Intermittent Claudication

ArticleYear
Genetic and environmental determinants of dimethylarginines and association with cardiovascular disease in patients with type 2 diabetes.
    Diabetes care, 2014, Volume: 37, Issue:3

    Topics: Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Environme

2014