n(g),n(g')-dimethyl-l-arginine has been researched along with Hyperuricemia in 4 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
Hyperuricemia: Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Uric acid is generated with reactive oxygen species via xanthine oxidase (XO), and hyperuricemia, which is identified as the excess of uric acid in the blood, has been associated with vascular endothelial dysfunction." | 9.34 | Randomized, Open-Label, Cross-Over Comparison of the Effects of Benzbromarone and Febuxostat on Endothelial Function in Patients with Hyperuricemia. ( Doi, Y; Fukae, S; Ikeda, S; Kawano, H; Koga, S; Maemura, K; Minami, T; Nakata, T; Tsuneto, A; Yonekura, T, 2020) |
| "Uric acid is generated with reactive oxygen species via xanthine oxidase (XO), and hyperuricemia, which is identified as the excess of uric acid in the blood, has been associated with vascular endothelial dysfunction." | 5.34 | Randomized, Open-Label, Cross-Over Comparison of the Effects of Benzbromarone and Febuxostat on Endothelial Function in Patients with Hyperuricemia. ( Doi, Y; Fukae, S; Ikeda, S; Kawano, H; Koga, S; Maemura, K; Minami, T; Nakata, T; Tsuneto, A; Yonekura, T, 2020) |
| " Since disturbed NO bioavailability is a major pathway whereby high uric may cause renal damage, we tested the interaction between the major endogenous inhibitor of NO synthase, asymmetric-dimethylargine (ADMA), and the rs734553 polymorphism for CKD progression in the same cohort." | 1.42 | Synergism between asymmetric dimethylarginine (ADMA) and a genetic marker of uric acid in CKD progression. ( Leonardis, D; Mallamaci, F; Pisano, A; Sanguedolce, MC; Spoto, B; Testa, A; Tripepi, G; Zoccali, C, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakata, T | 1 |
| Ikeda, S | 1 |
| Koga, S | 1 |
| Yonekura, T | 1 |
| Tsuneto, A | 1 |
| Doi, Y | 1 |
| Fukae, S | 1 |
| Minami, T | 1 |
| Kawano, H | 1 |
| Maemura, K | 1 |
| Lee, TS | 1 |
| Lu, TM | 1 |
| Chen, CH | 1 |
| Guo, BC | 1 |
| Hsu, CP | 1 |
| Testa, A | 1 |
| Mallamaci, F | 1 |
| Leonardis, D | 1 |
| Spoto, B | 1 |
| Pisano, A | 1 |
| Sanguedolce, MC | 1 |
| Tripepi, G | 1 |
| Zoccali, C | 1 |
| Toyohara, T | 1 |
| Abe, T | 1 |
1 review available for n(g),n(g')-dimethyl-l-arginine and Hyperuricemia
| Article | Year |
|---|---|
[Analysis of transporter function and development to clinical application].
Topics: Aconitic Acid; Animals; Arginine; Guanidines; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors | 2011 |
1 trial available for n(g),n(g')-dimethyl-l-arginine and Hyperuricemia
| Article | Year |
|---|---|
Randomized, Open-Label, Cross-Over Comparison of the Effects of Benzbromarone and Febuxostat on Endothelial Function in Patients with Hyperuricemia.
Topics: Adiponectin; Aged; Arginine; Benzbromarone; Cross-Over Studies; Endothelium, Vascular; Febuxostat; F | 2020 |
2 other studies available for n(g),n(g')-dimethyl-l-arginine and Hyperuricemia
| Article | Year |
|---|---|
Hyperuricemia induces endothelial dysfunction and accelerates atherosclerosis by disturbing the asymmetric dimethylarginine/dimethylarginine dimethylaminotransferase 2 pathway.
Topics: Amidohydrolases; Animals; Arginine; Atherosclerosis; Endothelial Cells; Humans; Hyperuricemia; Mice; | 2021 |
Synergism between asymmetric dimethylarginine (ADMA) and a genetic marker of uric acid in CKD progression.
Topics: Aged; Alleles; Arginine; C-Reactive Protein; Calcium; Case-Control Studies; Cohort Studies; Creatini | 2015 |