Page last updated: 2024-10-17

n(g),n(g')-dimethyl-l-arginine and Hypertension, Renal

n(g),n(g')-dimethyl-l-arginine has been researched along with Hypertension, Renal in 8 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Hypertension, Renal: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.

Research Excerpts

ExcerptRelevanceReference
" Melatonin therapy prevented L-NAME-exacerbated hypertension and nephrosclerosis in young SHRs."3.80Renoprotective effects of melatonin in young spontaneously hypertensive rats with L-NAME. ( Cheng, MC; Huang, LT; Tain, YL; Wu, TH, 2014)
"To establish the role played by the circulating nitric oxide synthase inhibitors N(G)-monomethyl-L-arginine (L-NMMA), asymmetrical dimethyl arginine (ADMA) and symmetric dimethyl arginine (SDMA) and its association with hypertension of children and adolescents."3.69Nitric oxide synthase inhibitors and hypertension in children and adolescents. ( Dillon, MJ; Frend, A; Goonasekera, CD; Rees, DD; Shah, V; Woolard, P, 1997)
"Patients with end-stage renal disease (ESRD) receiving hemodialysis (HD) treatment have a markedly shortened life expectancy in large part owing to cardiovascular disease (CVD), not explained by established risk factors."2.72Effects of amlodipine and valsartan on oxidative stress and plasma methylarginines in end-stage renal disease patients on hemodialysis. ( Aslam, S; Leone, A; Santha, T; Wilcox, C, 2006)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's4 (50.00)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheng, MC1
Wu, TH1
Huang, LT1
Tain, YL1
Sasser, JM1
Moningka, NC1
Cunningham, MW1
Croker, B1
Baylis, C1
Northcott, CA1
Billecke, S1
Craig, T1
Hinojosa-Laborde, C1
Patel, KP1
Chen, AF1
D'Alecy, LG1
Haywood, JR1
Yamaguchi, Y1
Aslam, S1
Santha, T1
Leone, A1
Wilcox, C1
Schiffrin, EL1
Lipman, ML1
Mann, JF1
Goonasekera, CD1
Rees, DD1
Woolard, P1
Frend, A1
Shah, V2
Dillon, MJ1
Raj, DS1
Vincent, B1
Simpson, K1
Sato, E1
Jones, KL1
Welbourne, TC1
Levi, M1
Blandon, P1
Zager, P1
Robbins, RA1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Influence of Preoperative Hemodialysis or Intraoperative Modified Ultrafiltration on Postoperative Outcome for Patients With Severe Renal Dysfunction Undergoing Open Heart Surgery: Randomized, Controlled, Multicenter Clinical Trial[NCT00720967]Phase 3450 participants (Anticipated)Interventional2008-11-30Not yet recruiting
Effect of Beraprost Sodium on Arterial Stiffness in Patients With Type 2 Diabetic Nephropathy (BESTinDN Study)[NCT01796418]102 participants (Anticipated)Interventional2013-03-31Recruiting
A Multicenter, Randomized Trial to Compare Xience and Vision Coronary Stents in the Same Multivessel Patient With Chronic Kidney Disease[NCT00818792]Phase 2215 participants (Actual)Interventional2009-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for n(g),n(g')-dimethyl-l-arginine and Hypertension, Renal

ArticleYear
[Nephrosclerosis: Pathogenesis, pathophysiology, and therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 2

    Topics: Animals; Arginine; Atherosclerosis; Embolism, Cholesterol; Endothelium, Vascular; Free Radicals; Hom

2006
Chronic kidney disease: effects on the cardiovascular system.
    Circulation, 2007, Jul-03, Volume: 116, Issue:1

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker

2007
Chronic kidney disease: effects on the cardiovascular system.
    Circulation, 2007, Jul-03, Volume: 116, Issue:1

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker

2007
Chronic kidney disease: effects on the cardiovascular system.
    Circulation, 2007, Jul-03, Volume: 116, Issue:1

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker

2007
Chronic kidney disease: effects on the cardiovascular system.
    Circulation, 2007, Jul-03, Volume: 116, Issue:1

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker

2007
Chronic kidney disease: effects on the cardiovascular system.
    Circulation, 2007, Jul-03, Volume: 116, Issue:1

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker

2007
Chronic kidney disease: effects on the cardiovascular system.
    Circulation, 2007, Jul-03, Volume: 116, Issue:1

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker

2007
Chronic kidney disease: effects on the cardiovascular system.
    Circulation, 2007, Jul-03, Volume: 116, Issue:1

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker

2007
Chronic kidney disease: effects on the cardiovascular system.
    Circulation, 2007, Jul-03, Volume: 116, Issue:1

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker

2007
Chronic kidney disease: effects on the cardiovascular system.
    Circulation, 2007, Jul-03, Volume: 116, Issue:1

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker

2007

Trials

1 trial available for n(g),n(g')-dimethyl-l-arginine and Hypertension, Renal

ArticleYear
Effects of amlodipine and valsartan on oxidative stress and plasma methylarginines in end-stage renal disease patients on hemodialysis.
    Kidney international, 2006, Volume: 70, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Arginine; Blood

2006

Other Studies

5 other studies available for n(g),n(g')-dimethyl-l-arginine and Hypertension, Renal

ArticleYear
Renoprotective effects of melatonin in young spontaneously hypertensive rats with L-NAME.
    Pediatrics and neonatology, 2014, Volume: 55, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Amidohydrolases; Animals; Antioxidants; Arginine; Blood Pressure; Deoxy

2014
Asymmetric dimethylarginine in angiotensin II-induced hypertension.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Volume: 298, Issue:3

    Topics: Amidohydrolases; Angiotensin II; Animals; Arginine; Blood Pressure; Fibrosis; Hypertension, Renal; K

2010
Nitric oxide synthase, ADMA, SDMA, and nitric oxide activity in the paraventricular nucleus throughout the etiology of renal wrap hypertension.
    American journal of physiology. Heart and circulatory physiology, 2012, Jun-01, Volume: 302, Issue:11

    Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Hypertension, Renal; K

2012
Nitric oxide synthase inhibitors and hypertension in children and adolescents.
    Journal of hypertension, 1997, Volume: 15, Issue:8

    Topics: Adolescent; Animals; Arginine; Child; Endothelium, Vascular; Enzyme Inhibitors; Female; Glomerular F

1997
Hemodynamic changes during hemodialysis: role of nitric oxide and endothelin.
    Kidney international, 2002, Volume: 61, Issue:2

    Topics: Adult; Aged; Arginine; Endothelin-1; Female; Humans; Hypertension, Renal; Hypotension; Kidney Failur

2002