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n(g),n(g')-dimethyl-l-arginine and Hyperlipemia

n(g),n(g')-dimethyl-l-arginine has been researched along with Hyperlipemia in 14 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Research Excerpts

ExcerptRelevanceReference
"BET supplementation may be effective in preventing hyperlipidemia, disturbed NO availability, oxidative stress, and the development of fatty liver and atherosclerotic lesions that might result from excess amounts of cholesterol and methionine in the diet."7.88Effects of betaine supplementation on nitric oxide metabolism, atherosclerotic parameters, and fatty liver in guinea pigs fed a high cholesterol plus methionine diet. ( Bekpınar, S; Çevik, A; Genc, S; Gürdöl, F; Küskü-Kiraz, Z; Olgaç, V; Ünlücerci, Y; Uysal, M, 2018)
"Global L-arginine bioavailability was diminished, whereas plasma arginase activity, ADMA, and SDMA levels were elevated, in patients with RA compared with healthy control subjects."5.48Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis. ( Chandrasekharan, UM; Elaine Husni, M; Hazen, SL; Wang, S; Wang, Z; Wilson Tang, WH; Wu, Y, 2018)
" A total of 83 patients with hypercholesterolemia and angiographically documented mild coronary artery stenosis were randomized to rosuvastatin treatment (20 mg) or atorvastatin treatment (40 mg) once daily for 6 weeks after a 4-week dietary lead-in phase."5.19Comparision of effects of rosuvastatin versus atorvastatin treatment on plasma levels of asymmetric dimethylarginine in patients with hyperlipidemia having coronary artery disease. ( Akturk, E; Altas, Y; Atas, H; Balta, S; Can, C; Demirkol, S; Erdem, K; Korkmaz, H; Kurtoglu, E; Sincer, I; Yilmaz, M, 2014)
" Thus, together with classic risk factors such as hypertension, dyslipidemia and diabetes, other situations such as microinflammation, increased concentration of asymmetrical dimethyl-L-arginine, disturbed phosphate metabolism and anemia may represent important risk factors for accelerated atherosclerosis in dialyzed patients."4.82Atherosclerosis in dialyzed patients. ( Ritz, E, 2004)
"BET supplementation may be effective in preventing hyperlipidemia, disturbed NO availability, oxidative stress, and the development of fatty liver and atherosclerotic lesions that might result from excess amounts of cholesterol and methionine in the diet."3.88Effects of betaine supplementation on nitric oxide metabolism, atherosclerotic parameters, and fatty liver in guinea pigs fed a high cholesterol plus methionine diet. ( Bekpınar, S; Çevik, A; Genc, S; Gürdöl, F; Küskü-Kiraz, Z; Olgaç, V; Ünlücerci, Y; Uysal, M, 2018)
"Treatment with fenofibrate did not alter plasma ADMA level, in contrast to serum triglycerides which were significantly lowered and plasma total homocysteine which was significantly increased."2.71Fenofibrate increases the L-arginine:ADMA ratio by increase of L-arginine concentration but has no effect on ADMA concentration. ( Bode-Böger, SM; Dierkes, J; Luley, C; Martens-Lobenhoffer, J; Westphal, S, 2004)
"Global L-arginine bioavailability was diminished, whereas plasma arginase activity, ADMA, and SDMA levels were elevated, in patients with RA compared with healthy control subjects."1.48Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis. ( Chandrasekharan, UM; Elaine Husni, M; Hazen, SL; Wang, S; Wang, Z; Wilson Tang, WH; Wu, Y, 2018)
"Captopril treatment not only decreased vascular intima thickening and serum ADMA concentration but also preserved vascular DDAH activity and endothelium-dependent relaxation in hyperlipidemic rabbits without influence on serum lipid profiles."1.46Preservation of vascular DDAH activity contributes to the protection of captopril against endothelial dysfunction in hyperlipidemic rabbits. ( Feng, M; He, ZM; Lei, YP; Lin, Y; Lu, CW; Xiong, Y, 2017)
"In the multivariate analysis dyslipidemia, left ventricular hypertrophy, age and LDL-c (negatively) were associated with CVD."1.36[Prevalence of cardiovascular disease in uraemia and relevance of cardiovascular risk factors]. ( Azqueta, M; Cases, A; Coll, E; Collado, S; Cruzado, JM; de la Torre, B; Deulofeu, R; Guerrero, L; Nicolau, C; Pons, M; Vera, M, 2010)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's4 (28.57)29.6817
2010's9 (64.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, CH1
Zhao, JF1
Hsu, CP1
Kou, YR1
Lu, TM1
Lee, TS1
Szentpéteri, A1
Zsíros, N1
Varga, VE1
Lőrincz, H1
Katkó, M1
Seres, I1
Fülöp, P1
Paragh, G1
Harangi, M1
Küskü-Kiraz, Z1
Genc, S1
Bekpınar, S1
Ünlücerci, Y1
Çevik, A1
Olgaç, V1
Gürdöl, F1
Uysal, M1
Chandrasekharan, UM1
Wang, Z1
Wu, Y1
Wilson Tang, WH1
Hazen, SL1
Wang, S1
Elaine Husni, M1
Kasapkara, ÇS1
Tümer, L1
Biberoglu, G1
Kasapkara, A1
Hasanoğlu, A1
Kurtoglu, E1
Balta, S1
Sincer, I1
Altas, Y1
Atas, H1
Yilmaz, M1
Korkmaz, H1
Erdem, K1
Akturk, E1
Demirkol, S1
Can, C1
Lin, Y1
Feng, M1
Lu, CW1
Lei, YP1
He, ZM1
Xiong, Y2
Durmus, N1
Toylu, A1
Evcim, S1
Soner, BC1
Demir, O1
Kahraman, E1
Demir, T1
Irer, B1
Gidener, S1
Atabey, N1
Esen, A1
Collado, S1
Coll, E1
Deulofeu, R1
Guerrero, L1
Pons, M1
Cruzado, JM1
de la Torre, B1
Vera, M1
Azqueta, M1
Nicolau, C1
Cases, A1
Zoccali, C1
Böger, RH1
Vallance, P1
Cooke, JP1
Ritz, E1
Dierkes, J1
Westphal, S1
Martens-Lobenhoffer, J1
Luley, C1
Bode-Böger, SM1
Li, YJ1
Yu, XJ1
Liu, GZ1
Li, NS1

Reviews

2 reviews available for n(g),n(g')-dimethyl-l-arginine and Hyperlipemia

ArticleYear
[Cardiovascular events in chronic advanced renal insufficiency. Current concepts].
    Recenti progressi in medicina, 2003, Volume: 94, Issue:3

    Topics: Anemia; Arginine; C-Reactive Protein; Cardiovascular Diseases; Humans; Hyperhomocysteinemia; Hyperli

2003
Atherosclerosis in dialyzed patients.
    Blood purification, 2004, Volume: 22, Issue:1

    Topics: Anemia; Animals; Arginine; Arteriosclerosis; Biomarkers; Cause of Death; Comorbidity; Coronary Arter

2004

Trials

2 trials available for n(g),n(g')-dimethyl-l-arginine and Hyperlipemia

ArticleYear
Comparision of effects of rosuvastatin versus atorvastatin treatment on plasma levels of asymmetric dimethylarginine in patients with hyperlipidemia having coronary artery disease.
    Angiology, 2014, Volume: 65, Issue:9

    Topics: Arginine; Atorvastatin; Biomarkers; Coronary Angiography; Coronary Stenosis; Down-Regulation; Female

2014
Fenofibrate increases the L-arginine:ADMA ratio by increase of L-arginine concentration but has no effect on ADMA concentration.
    Atherosclerosis, 2004, Volume: 173, Issue:2

    Topics: Adult; Arginine; Biomarkers; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Meth

2004

Other Studies

10 other studies available for n(g),n(g')-dimethyl-l-arginine and Hyperlipemia

ArticleYear
The detrimental effect of asymmetric dimethylarginine on cholesterol efflux of macrophage foam cells: Role of the NOX/ROS signaling.
    Free radical biology & medicine, 2019, 11-01, Volume: 143

    Topics: Amidohydrolases; Animals; Arginine; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transpo

2019
Paraoxonase-1 and myeloperoxidase correlate with vascular biomarkers in overweight patients with newly diagnosed untreated hyperlipidaemia.
    VASA. Zeitschrift fur Gefasskrankheiten, 2017, Volume: 46, Issue:5

    Topics: Adult; Aged; Arginine; Aryldialkylphosphatase; Biomarkers; C-Reactive Protein; Case-Control Studies;

2017
Effects of betaine supplementation on nitric oxide metabolism, atherosclerotic parameters, and fatty liver in guinea pigs fed a high cholesterol plus methionine diet.
    Nutrition (Burbank, Los Angeles County, Calif.), 2018, Volume: 45

    Topics: Animals; Arginine; Atherosclerosis; Betaine; Cholesterol; Cholesterol, Dietary; Diet, High-Fat; Diet

2018
Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis.
    Arthritis research & therapy, 2018, 06-08, Volume: 20, Issue:1

    Topics: Aged; Arginase; Arginine; Arthritis, Rheumatoid; Biomarkers; Cardiovascular Diseases; Comorbidity; F

2018
Asymmetric dimethylarginine (ADMA) and L-arginine levels in children with glycogen storage disease type I.
    Journal of pediatric endocrinology & metabolism : JPEM, 2013, Volume: 26, Issue:5-6

    Topics: Adolescent; Arginine; Child; Child, Preschool; Fatty Acids; Female; Glycogen Storage Disease Type I;

2013
Preservation of vascular DDAH activity contributes to the protection of captopril against endothelial dysfunction in hyperlipidemic rabbits.
    European journal of pharmacology, 2017, Mar-05, Volume: 798

    Topics: Amidohydrolases; Animals; Arginine; Captopril; Diet, High-Fat; Endothelium, Vascular; Enzyme Inhibit

2017
Time-course changes of nLDL-induced erectile dysfunction.
    International journal of impotence research, 2017, Volume: 29, Issue:3

    Topics: Animals; Arginine; Disease Models, Animal; Endothelium, Vascular; Erectile Dysfunction; Hyperlipidem

2017
[Prevalence of cardiovascular disease in uraemia and relevance of cardiovascular risk factors].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2010, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Blood Proteins; Cardiovascular Diseases; Comorbidity;

2010
Asymmetric dimethylarginine (ADMA): a key regulator of nitric oxide synthase.
    Atherosclerosis. Supplements, 2003, Volume: 4, Issue:4

    Topics: Arginine; Cardiovascular Diseases; Endothelium, Vascular; Enzyme Inhibitors; Homeostasis; Humans; Hy

2003
Endogenous inhibitors of nitric oxide synthesis and lipid peroxidation in hyperlipidemic rabbits.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:2

    Topics: Animals; Aorta, Thoracic; Arginine; Hyperlipidemias; Lipid Peroxidation; Male; Malondialdehyde; Nitr

1996