n(g),n(g')-dimethyl-l-arginine has been researched along with Hemolysis in 7 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Asymmetric dimethylarginine (ADMA) is associated with pulmonary hypertension (PHT) in sickle cell disease (SCD)." | 3.76 | Plasma asymmetric dimethylarginine concentrations in sickle cell disease are related to the hemolytic phenotype. ( Biemond, BJ; Brandjes, DP; Duits, AJ; Landburg, PP; Muskiet, FA; Schnog, JB; Teerlink, T, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benites, BD | 1 |
| Olalla-Saad, ST | 1 |
| El-Shanshory, M | 1 |
| Badraia, I | 1 |
| Donia, A | 1 |
| Abd El-Hameed, F | 1 |
| Mabrouk, M | 1 |
| Kline, JA | 1 |
| Watts, J | 1 |
| Courtney, D | 1 |
| Lee, YY | 1 |
| Hwang, S | 1 |
| Kato, GJ | 1 |
| Wang, Z | 1 |
| Machado, RF | 1 |
| Blackwelder, WC | 1 |
| Taylor, JG | 1 |
| Hazen, SL | 1 |
| Landburg, PP | 1 |
| Teerlink, T | 1 |
| Biemond, BJ | 1 |
| Brandjes, DP | 1 |
| Muskiet, FA | 1 |
| Duits, AJ | 1 |
| Schnog, JB | 1 |
| D'Alecy, LG | 1 |
| Billecke, SS | 1 |
| Böhmer, A | 1 |
| Großkopf, H | 1 |
| Jordan, J | 1 |
| Tsikas, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Expired CO2/O2 Analysis to Diagnose Pulmonary Embolism[NCT00368836] | Phase 2/Phase 3 | 475 participants (Actual) | Interventional | 2006-01-31 | Completed | ||
| Determining the Prevalence and Prognosis of Secondary Pulmonary Hypertension in Adult Patients With Sickle Cell Anemia[NCT00011648] | 986 participants (Actual) | Observational | 2008-02-19 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
D-dimer > 499 ng/ml, etCO2/O2 < 0.28, Pulmonary Embolism diagnosed by CT scan (NCT00368836)
Timeframe: Measured at 45 days
| Intervention | probability of PE diagnosis (Number) |
|---|---|
| CO2/O2 Plus D-dimer | 0.32 |
| D-dimer | 0.17 |
Median postoperative change in end tidal CO2/O2 ratio calculated as 100% * [(postoperative-preoperative)/(preoperative)] (NCT00368836)
Timeframe: Pre-op measurement: the morning of surgery. Post-op measurement: the latter of postoperative day 3 or hospital discharge
| Intervention | percent change (Median) | |
|---|---|---|
| end tidal CO2/O2 ratio | D-dimer concentration | |
| BreathScreen PE | 0 | 136 |
1 review available for n(g),n(g')-dimethyl-l-arginine and Hemolysis
| Article | Year |
|---|---|
An update on arginine in sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Arginine; Hemolysis; Humans; Nitric Oxide; Nitric Oxide Synthase Type | 2019 |
6 other studies available for n(g),n(g')-dimethyl-l-arginine and Hemolysis
| Article | Year |
|---|---|
Asymmetric dimethylarginine levels in children with sickle cell disease and its correlation to tricuspid regurgitant jet velocity.
Topics: Adolescent; Anemia, Sickle Cell; Arginine; Blood Transfusion; Case-Control Studies; Child; Cross-Sec | 2013 |
Severe pulmonary embolism decreases plasma L-arginine.
Topics: Arginase; Arginine; Chromatography, High Pressure Liquid; Echocardiography, Doppler; Hemolysis; Huma | 2014 |
Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death.
Topics: Anemia, Sickle Cell; Arginine; Case-Control Studies; Citrulline; Follow-Up Studies; Hemolysis; Human | 2009 |
Plasma asymmetric dimethylarginine concentrations in sickle cell disease are related to the hemolytic phenotype.
Topics: Adult; Albuminuria; Anemia, Sickle Cell; Arginine; beta-Thalassemia; Cholelithiasis; Female; Hemolys | 2010 |
Massive quantities of asymmetric dimethylarginine (ADMA) are incorporated in red blood cell proteins and may be released by proteolysis following hemolytic stress.
Topics: Anemia, Sickle Cell; Arginine; Blood Proteins; Erythrocytes; Hemolysis; Humans | 2010 |
Human hemoglobin does not contain asymmetric dimethylarginine (ADMA).
Topics: Animals; Arginine; Erythrocytes; Gas Chromatography-Mass Spectrometry; Hemoglobins; Hemolysis; Human | 2012 |