n(g),n(g')-dimethyl-l-arginine has been researched along with Edema-Proteinuria-Hypertension Gestosis in 45 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the sequential trend of asymmetric dimethylarginine (ADMA), placental growth factor (PLGF) and pentraxin 3 (PTX 3) in pregnancies developing preeclampsia (PE) as compared to healthy pregnancy (HP) and to estimate their predictive value for development of PE later in pregnancy." | 7.88 | Estimation of asymmetric dimethylarginine (ADMA), placental growth factor (PLGF) and pentraxin 3 (PTX 3) in women with preeclampsia. ( Deepak, KK; Garg, P; Jaryal, AK; Kachhawa, G; Kriplani, A, 2018) |
| "Our previous study suggested that a lower l-arginine level (<70μM) at early gestation is associated with pregnancy-induced hypertension." | 7.85 | Association of serum asymmetric dimethylarginine, homocysteine, and l-arginine concentrations during early pregnancy with hypertensive disorders of pregnancy. ( Imai, K; Kajiyama, H; Kikkawa, F; Kotani, T; Maruta, E; Mitsui, T; Nakano, T; Nawa, A; Niwa, Y; Sumigama, S; Tamakoshi, K; Tsuda, H; Wang, J; Yamashita, M; Yoshida, S, 2017) |
| "To evaluate the usefulness of serial determinations of asymmetric dimethylarginine (ADMA) and homocysteine (Hcy) concentrations during pregnancy to predict pre-eclampsia, taking into account maternal obesity and B vitamin status." | 7.81 | Serial determinations of asymmetric dimethylarginine and homocysteine during pregnancy to predict pre-eclampsia: a longitudinal study. ( Hinojosa-Cruz, JC; Leaños-Miranda, A; López-Alarcón, M; Martínez-Basila, A; Montalvo-Velarde, I; Vital-Reyes, VS, 2015) |
| "The aim of our study was to investigate the association between homocysteine and asymmetric dimethylarginine in preeclamptic women with and without intrauterine growth restriction compared with normal healthy uncomplicated pregnancies and normotensive pregnancies complicated by idiopathic isolated intrauterine fetal growth restriction." | 7.79 | Differences in the association between maternal serum homocysteine and ADMA levels in women with pregnancies complicated by preeclampsia and/or intrauterine growth restriction. ( Laskowska, K; Laskowska, M; Oleszczuk, J, 2013) |
| "The aim of this study was to investigate maternal asymmetric dimethylarginine (ADMA) concentrations at the three trimesters of pregnancy in uncomplicated pregnancies and in women who developed preeclampsia or had small for gestational age infants (SGA) without preeclampsia." | 7.78 | Levels of asymmetric dimethylarginine throughout normal pregnancy and in pregnancies complicated with preeclampsia or had a small for gestational age baby. ( Batakis, E; Botsis, D; Eleftheriades, M; Haliassos, A; Hassiakos, D; Rizos, D; Rizou, M, 2012) |
| " We analyzed the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and asymmetric dimethylarginine (ADMA) in 55 Turkish patients with PE without fetal growth retardation (FGR) and in 54 healthy pregnant women." | 7.76 | Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and plasma concentrations of asymmetric dimethylarginine in Turkish pre-eclamptic women without fetal growth retardation. ( Ateş, K; Ilhan, N; Kafkasli, A; Kaman, D; Turan, F, 2010) |
| "The purpose of this study was to investigate maternal plasma concentrations of asymmetric dimethylarginine (ADMA) in mid pregnancy and at the time of disease in women who experience preeclampsia, compared with women with uncomplicated pregnancies and women with small-for-gestational-age infants." | 7.74 | Elevated asymmetric dimethylarginine concentrations precede clinical preeclampsia, but not pregnancies with small-for-gestational-age infants. ( Frank, MP; Harger, G; Markovic, N; Powers, RW; Roberts, JM; Speer, PD, 2008) |
| "In fact, hallmark features of preeclampsia (PE) result from vessel involvement and demonstrate maternal endothelium as a target tissue." | 6.61 | The Role of Nitric Oxide, ADMA, and Homocysteine in The Etiopathogenesis of Preeclampsia-Review. ( Dymara-Konopka, W; Laskowska, M, 2019) |
| "Preeclampsia is a major cause of maternal and neonatal morbidity and mortality worldwide." | 6.46 | The role of nitric oxide synthase inhibition by asymmetric dimethylarginine in the pathophysiology of preeclampsia. ( Böger, RH; Diemert, A; Hecher, K; Lüneburg, N; Maas, R; Schwedhelm, E, 2010) |
| "Suramin treatment exerted negligible effect on the RAS pathway in the adult male offspring kidneys." | 5.43 | N-Acetylcysteine Prevents Programmed Hypertension in Male Rat Offspring Born to Suramin-Treated Mothers. ( Hsu, CN; Lee, CT; Lin, YJ; Tain, YL; Tsai, CC, 2016) |
| "Decreased DDAH and HO with preeclampsia suggest that they are important points in the regulatory pathways of NO and CO production that are altered in preeclampsia." | 5.39 | Nitric oxide and carbon monoxide production and metabolism in preeclampsia. ( Chan, K; Chen, DB; Ehsanipoor, RM; Fitzmaurice, LE; Fortson, W; Liao, WX; Wing, DA, 2013) |
| "Preeclampsia is a syndrome characterized by hypertension and proteinuria." | 5.37 | The role of asymmetric dimethyl arginine and oxidant/antioxidant system in preeclampsia. ( Akalin, S; Akgul, EO; Alacam, H; Aydin, I; Cakir, E; Danisman, N; Deren, O; Dikmen, ZG; Dogan, P; Keskin, U; Kurt, YG; Polat, B; Yaman, H, 2011) |
| "Women with preeclampsia (n = 47) and controls (n = 51) who gave birth by cesarean section were included in the study." | 5.35 | Asymmetric dimethylarginine in the maternal and fetal circulation in preeclampsia. ( Braekke, K; Harsem, NK; Staff, AC; Ueland, PM, 2009) |
| "Asymmetric dimethylarginine (ADMA) is a competitive endogenous inhibitor of nitric oxide synthase with a key role in the pathophysiology of endothelial dysfunction, in the progression of atherosclerosis and in cardiovascular diseases." | 4.91 | Asymmetric Dimethylarginine: Clinical Significance and Novel Therapeutic Approaches. ( Georgakis, MK; Latsios, G; Oikonomou, E; Papageorgiou, N; Papaioannou, S; Siasos, G; Tousoulis, D; Zaromitidou, M, 2015) |
| "To evaluate the sequential trend of asymmetric dimethylarginine (ADMA), placental growth factor (PLGF) and pentraxin 3 (PTX 3) in pregnancies developing preeclampsia (PE) as compared to healthy pregnancy (HP) and to estimate their predictive value for development of PE later in pregnancy." | 3.88 | Estimation of asymmetric dimethylarginine (ADMA), placental growth factor (PLGF) and pentraxin 3 (PTX 3) in women with preeclampsia. ( Deepak, KK; Garg, P; Jaryal, AK; Kachhawa, G; Kriplani, A, 2018) |
| "Our previous study suggested that a lower l-arginine level (<70μM) at early gestation is associated with pregnancy-induced hypertension." | 3.85 | Association of serum asymmetric dimethylarginine, homocysteine, and l-arginine concentrations during early pregnancy with hypertensive disorders of pregnancy. ( Imai, K; Kajiyama, H; Kikkawa, F; Kotani, T; Maruta, E; Mitsui, T; Nakano, T; Nawa, A; Niwa, Y; Sumigama, S; Tamakoshi, K; Tsuda, H; Wang, J; Yamashita, M; Yoshida, S, 2017) |
| " Maternal characteristics, uterine artery pulsatility index (UtA-PI), ductus venosus pulsatility index (DV-PI) and serum biomarkers including pregnancy associated plasma protein - A (PAPP-A), placental growth factor (PlGF), soluble fms-like tyrosine kinase 1 (sFlt-1), s-Flt-1/PLGF ratio, asymmetric dimethylarginine (ADMA), matrix metalloproteinase 9 (MMP-9), neutrophil gelatinase-associated lipocalin (NGAL) and MMP-9/NGAL complex were recorded." | 3.83 | Prediction of pre-eclampsia combining NGAL and other biochemical markers with Doppler in the first and/or second trimester of pregnancy. A pilot study. ( Eleftheriades, MI; Haliassos, AD; Karampas, GA; Mastorakos, GP; Metallinou, DK; Panoulis, KC; Rizos, DA; Rizou, MD, 2016) |
| "To evaluate the usefulness of serial determinations of asymmetric dimethylarginine (ADMA) and homocysteine (Hcy) concentrations during pregnancy to predict pre-eclampsia, taking into account maternal obesity and B vitamin status." | 3.81 | Serial determinations of asymmetric dimethylarginine and homocysteine during pregnancy to predict pre-eclampsia: a longitudinal study. ( Hinojosa-Cruz, JC; Leaños-Miranda, A; López-Alarcón, M; Martínez-Basila, A; Montalvo-Velarde, I; Vital-Reyes, VS, 2015) |
| "The present case-control study was undertaken to investigate l-arginine metabolism in pregnant women with early-onset and late-onset pre-eclampsia." | 3.79 | L-arginine metabolism in early-onset and late-onset pre-eclamptic pregnancies. ( Bode-Böger, SM; Bódis, J; Hantosi, E; Kovács, GL; Martens-Lobenhoffer, J; Molnár, G; Sulyok, E; Tamás, P, 2013) |
| "The aim of our study was to investigate the association between homocysteine and asymmetric dimethylarginine in preeclamptic women with and without intrauterine growth restriction compared with normal healthy uncomplicated pregnancies and normotensive pregnancies complicated by idiopathic isolated intrauterine fetal growth restriction." | 3.79 | Differences in the association between maternal serum homocysteine and ADMA levels in women with pregnancies complicated by preeclampsia and/or intrauterine growth restriction. ( Laskowska, K; Laskowska, M; Oleszczuk, J, 2013) |
| "The aim of this study was to investigate maternal asymmetric dimethylarginine (ADMA) concentrations at the three trimesters of pregnancy in uncomplicated pregnancies and in women who developed preeclampsia or had small for gestational age infants (SGA) without preeclampsia." | 3.78 | Levels of asymmetric dimethylarginine throughout normal pregnancy and in pregnancies complicated with preeclampsia or had a small for gestational age baby. ( Batakis, E; Botsis, D; Eleftheriades, M; Haliassos, A; Hassiakos, D; Rizos, D; Rizou, M, 2012) |
| " We analyzed the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and asymmetric dimethylarginine (ADMA) in 55 Turkish patients with PE without fetal growth retardation (FGR) and in 54 healthy pregnant women." | 3.76 | Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and plasma concentrations of asymmetric dimethylarginine in Turkish pre-eclamptic women without fetal growth retardation. ( Ateş, K; Ilhan, N; Kafkasli, A; Kaman, D; Turan, F, 2010) |
| "The purpose of this study was to investigate maternal plasma concentrations of asymmetric dimethylarginine (ADMA) in mid pregnancy and at the time of disease in women who experience preeclampsia, compared with women with uncomplicated pregnancies and women with small-for-gestational-age infants." | 3.74 | Elevated asymmetric dimethylarginine concentrations precede clinical preeclampsia, but not pregnancies with small-for-gestational-age infants. ( Frank, MP; Harger, G; Markovic, N; Powers, RW; Roberts, JM; Speer, PD, 2008) |
| "An endogenous inhibitor of nitric oxide synthase (NOS), NG,NG dimethylarginine (asymmetric dimethylarginine, ADMA), which is present in human plasma and urine, has been reported to be elevated in the plasma of women with pre-eclampsia." | 3.69 | Effect of asymmetric dimethyl arginine on nitric oxide synthase activity in normal and pre-eclamptic placentae. ( Brennecke, SP; Di Iulio, JL; Gude, NM; King, RG, 1995) |
| "In fact, hallmark features of preeclampsia (PE) result from vessel involvement and demonstrate maternal endothelium as a target tissue." | 2.61 | The Role of Nitric Oxide, ADMA, and Homocysteine in The Etiopathogenesis of Preeclampsia-Review. ( Dymara-Konopka, W; Laskowska, M, 2019) |
| "Preeclampsia is a major cause of maternal and neonatal morbidity and mortality worldwide." | 2.46 | The role of nitric oxide synthase inhibition by asymmetric dimethylarginine in the pathophysiology of preeclampsia. ( Böger, RH; Diemert, A; Hecher, K; Lüneburg, N; Maas, R; Schwedhelm, E, 2010) |
| "Elevated ADMA levels in preeclampsia are seen before clinical symptoms have developed; these findings suggest that ADMA has a role in the pathogenesis of preeclampsia." | 2.43 | Endogenous inhibitors of nitric oxide and preeclampsia: a review. ( Dekker, G; Jeffries, B; Slaghekke, F, 2006) |
| "SVRI and SDMA were higher in preeclampsia overall, in early onset and late onset compared to controls." | 1.46 | Systemic vascular resistance and endogenous inhibitors of nitric oxide synthesis in early- compared to late-onset preeclampsia: preliminary findings. ( Lackner, HK; Lucovnik, M; Moertl, MG; Papousek, I; Roessler, A; Schmid-Zalaudek, K; Schulter, G, 2017) |
| "Suramin treatment exerted negligible effect on the RAS pathway in the adult male offspring kidneys." | 1.43 | N-Acetylcysteine Prevents Programmed Hypertension in Male Rat Offspring Born to Suramin-Treated Mothers. ( Hsu, CN; Lee, CT; Lin, YJ; Tain, YL; Tsai, CC, 2016) |
| "Forty-four women developed preeclampsia." | 1.42 | First-Trimester Maternal Serum Levels of sFLT1, PGF and ADMA Predict Preeclampsia. ( Bian, Z; Duan, T; Shixia, C, 2015) |
| "Severe preeclampsia was defined as blood pressure> 160/110 mmHg with proteinuria> 5 g in a 24-h urinary protein excretion." | 1.42 | The relation of maternal serum eNOS, NOSTRIN and ADMA levels with aetiopathogenesis of preeclampsia and/or intrauterine fetal growth restriction. ( Laskowska, K; Laskowska, M; Oleszczuk, J, 2015) |
| "Preeclampsia is a pregnancy-related pathological condition triggered by an abnormal placentation which produces endothelial dysfunction (ED)." | 1.42 | [Interactions between markers of endothelial damage (homocysteine and asymmetric dimethylarginine) and antioxidants and B-vitamins in preeclamptic women]. ( Hinojosa-Cruz, JC; López-Alarcón, M; Montalvo-Velarde, I; Puellotamara, E; Vital-Reyes, VS, 2015) |
| "Decreased DDAH and HO with preeclampsia suggest that they are important points in the regulatory pathways of NO and CO production that are altered in preeclampsia." | 1.39 | Nitric oxide and carbon monoxide production and metabolism in preeclampsia. ( Chan, K; Chen, DB; Ehsanipoor, RM; Fitzmaurice, LE; Fortson, W; Liao, WX; Wing, DA, 2013) |
| "Preeclampsia is a syndrome characterized by hypertension and proteinuria." | 1.37 | The role of asymmetric dimethyl arginine and oxidant/antioxidant system in preeclampsia. ( Akalin, S; Akgul, EO; Alacam, H; Aydin, I; Cakir, E; Danisman, N; Deren, O; Dikmen, ZG; Dogan, P; Keskin, U; Kurt, YG; Polat, B; Yaman, H, 2011) |
| "From Jan." | 1.35 | [Relationship between changes of endogenous nitric oxide synthase inhibitor and hydrolase and initiation of pre-eclampsia]. ( Chen, DJ; Huang, YY; Liu, HS; Lu, XH; Yao, XB, 2009) |
| "Women with preeclampsia (n = 47) and controls (n = 51) who gave birth by cesarean section were included in the study." | 1.35 | Asymmetric dimethylarginine in the maternal and fetal circulation in preeclampsia. ( Braekke, K; Harsem, NK; Staff, AC; Ueland, PM, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (4.44) | 18.2507 |
| 2000's | 11 (24.44) | 29.6817 |
| 2010's | 31 (68.89) | 24.3611 |
| 2020's | 1 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Selanno, JF | 1 |
| Riu, DS | 1 |
| Tessy, T | 1 |
| Chalid, MT | 1 |
| Pelupessy, NU | 1 |
| Hartono, E | 1 |
| Lucovnik, M | 1 |
| Lackner, HK | 1 |
| Papousek, I | 1 |
| Schmid-Zalaudek, K | 1 |
| Schulter, G | 1 |
| Roessler, A | 1 |
| Moertl, MG | 1 |
| Maruta, E | 1 |
| Wang, J | 1 |
| Kotani, T | 1 |
| Tsuda, H | 1 |
| Nakano, T | 1 |
| Imai, K | 1 |
| Sumigama, S | 1 |
| Niwa, Y | 1 |
| Mitsui, T | 1 |
| Yoshida, S | 1 |
| Yamashita, M | 1 |
| Nawa, A | 1 |
| Tamakoshi, K | 1 |
| Kajiyama, H | 1 |
| Kikkawa, F | 1 |
| Tsikas, D | 3 |
| Bollenbach, A | 1 |
| Savvidou, MD | 2 |
| Garg, P | 1 |
| Jaryal, AK | 1 |
| Kachhawa, G | 1 |
| Deepak, KK | 1 |
| Kriplani, A | 1 |
| Németh, B | 1 |
| Murányi, E | 1 |
| Hegyi, P | 1 |
| Mátrai, P | 1 |
| Szakács, Z | 1 |
| Varjú, P | 1 |
| Hamvas, S | 1 |
| Tinusz, B | 1 |
| Budán, F | 1 |
| Czimmer, J | 1 |
| Bérczi, B | 1 |
| Erőss, B | 1 |
| Gyöngyi, Z | 1 |
| Kiss, I | 1 |
| Dymara-Konopka, W | 1 |
| Laskowska, M | 5 |
| El-Saka, MH | 1 |
| Madi, NM | 1 |
| Ibrahim, RR | 1 |
| Alghazaly, GM | 1 |
| Elshwaikh, S | 1 |
| El-Bermawy, M | 1 |
| Laskowska, K | 4 |
| Terbosh, M | 1 |
| Oleszczuk, J | 4 |
| Tamás, P | 1 |
| Bódis, J | 1 |
| Sulyok, E | 1 |
| Kovács, GL | 1 |
| Hantosi, E | 1 |
| Molnár, G | 1 |
| Martens-Lobenhoffer, J | 1 |
| Bode-Böger, SM | 1 |
| Alpoim, PN | 1 |
| Godoi, LC | 1 |
| Freitas, LG | 1 |
| Gomes, KB | 1 |
| Dusse, LM | 1 |
| Bian, Z | 1 |
| Shixia, C | 1 |
| Duan, T | 1 |
| Tousoulis, D | 1 |
| Georgakis, MK | 1 |
| Oikonomou, E | 1 |
| Papageorgiou, N | 1 |
| Zaromitidou, M | 1 |
| Latsios, G | 1 |
| Papaioannou, S | 1 |
| Siasos, G | 1 |
| López-Alarcón, M | 2 |
| Montalvo-Velarde, I | 2 |
| Vital-Reyes, VS | 2 |
| Hinojosa-Cruz, JC | 2 |
| Leaños-Miranda, A | 1 |
| Martínez-Basila, A | 1 |
| Puellotamara, E | 1 |
| Tain, YL | 1 |
| Hsu, CN | 1 |
| Lee, CT | 1 |
| Lin, YJ | 1 |
| Tsai, CC | 1 |
| Mayer-Pickel, K | 1 |
| Kolovetsiou-Kreiner, V | 1 |
| Mörtl, MG | 1 |
| Schlembach, D | 1 |
| Eberhard, K | 1 |
| Obermayer-Pietsch, B | 1 |
| Lang, U | 1 |
| Cervar-Zivkovic, M | 1 |
| Karampas, GA | 1 |
| Eleftheriades, MI | 1 |
| Panoulis, KC | 1 |
| Rizou, MD | 1 |
| Haliassos, AD | 1 |
| Metallinou, DK | 1 |
| Mastorakos, GP | 1 |
| Rizos, DA | 1 |
| Huang, YY | 1 |
| Yao, XB | 1 |
| Lu, XH | 1 |
| Liu, HS | 1 |
| Chen, DJ | 1 |
| Braekke, K | 1 |
| Ueland, PM | 1 |
| Harsem, NK | 1 |
| Staff, AC | 1 |
| Mao, D | 1 |
| Che, J | 1 |
| Li, K | 1 |
| Han, S | 1 |
| Yue, Q | 1 |
| Zhu, L | 1 |
| Zhang, W | 1 |
| Li, L | 1 |
| Böger, RH | 3 |
| Diemert, A | 1 |
| Schwedhelm, E | 2 |
| Lüneburg, N | 1 |
| Maas, R | 2 |
| Hecher, K | 1 |
| Sandrim, VC | 1 |
| Palei, AC | 1 |
| Metzger, IF | 1 |
| Cavalli, RC | 1 |
| Duarte, G | 1 |
| Tanus-Santos, JE | 1 |
| Turan, F | 1 |
| Ilhan, N | 1 |
| Kaman, D | 1 |
| Ateş, K | 1 |
| Kafkasli, A | 1 |
| Leszczyńska-Gorzelak, B | 1 |
| Rizos, D | 1 |
| Eleftheriades, M | 1 |
| Batakis, E | 1 |
| Rizou, M | 1 |
| Haliassos, A | 1 |
| Hassiakos, D | 1 |
| Botsis, D | 1 |
| Alacam, H | 1 |
| Dikmen, ZG | 1 |
| Yaman, H | 1 |
| Cakir, E | 1 |
| Deren, O | 1 |
| Akgul, EO | 1 |
| Aydin, I | 1 |
| Kurt, YG | 1 |
| Keskin, U | 1 |
| Akalin, S | 1 |
| Polat, B | 1 |
| Danisman, N | 1 |
| Dogan, P | 1 |
| Khalil, AA | 1 |
| Akolekar, R | 1 |
| Jordan, J | 1 |
| Nicolaides, KH | 2 |
| Demir, B | 1 |
| Demir, S | 1 |
| Pasa, S | 1 |
| Guven, S | 1 |
| Atamer, Y | 1 |
| Atamer, A | 1 |
| Kocyigit, Y | 1 |
| Masoura, S | 1 |
| Kalogiannidis, IA | 1 |
| Gitas, G | 1 |
| Goutsioulis, A | 1 |
| Koiou, E | 1 |
| Athanasiadis, A | 1 |
| Vavatsi, N | 1 |
| Ehsanipoor, RM | 1 |
| Fortson, W | 1 |
| Fitzmaurice, LE | 1 |
| Liao, WX | 1 |
| Wing, DA | 1 |
| Chen, DB | 1 |
| Chan, K | 1 |
| Chedraui, P | 1 |
| Solis, EJ | 1 |
| Bocci, G | 1 |
| Gopal, S | 1 |
| Russo, E | 1 |
| Escobar, GS | 1 |
| Hidalgo, L | 1 |
| Pérez-López, FR | 1 |
| Genazzani, AR | 1 |
| Mannella, P | 1 |
| Simoncini, T | 1 |
| Hingorani, AD | 1 |
| Frölich, JC | 1 |
| Vallance, P | 3 |
| Casas, JP | 1 |
| López-Jaramillo, P | 1 |
| Serrano, N | 1 |
| Díaz, LA | 1 |
| Leiper, J | 1 |
| Herrmann, W | 1 |
| Isber, S | 1 |
| Obeid, R | 1 |
| Herrmann, M | 1 |
| Jouma, M | 1 |
| Slaghekke, F | 1 |
| Dekker, G | 1 |
| Jeffries, B | 1 |
| Speer, PD | 1 |
| Powers, RW | 1 |
| Frank, MP | 1 |
| Harger, G | 1 |
| Markovic, N | 1 |
| Roberts, JM | 1 |
| Prefumo, F | 1 |
| Thilaganathan, B | 1 |
| Whitley, GS | 2 |
| Fickling, SA | 1 |
| Williams, D | 1 |
| Nussey, SS | 1 |
| King, RG | 1 |
| Di Iulio, JL | 1 |
| Gude, NM | 1 |
| Brennecke, SP | 1 |
| Ellis, J | 1 |
| Wennerholm, UB | 1 |
| Bengtsson, A | 1 |
| Lilja, H | 1 |
| Pettersson, A | 1 |
| Sultan, B | 1 |
| Wennergren, M | 1 |
| Hagberg, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Vascular Endothelial Growth Factor C/A 2578 Gene Polymorphism and Umbilical Artery Doppler in Preeclamptic Women[NCT03500588] | 290 participants (Actual) | Observational | 2017-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for n(g),n(g')-dimethyl-l-arginine and Edema-Proteinuria-Hypertension Gestosis
| Article | Year |
|---|---|
Asymmetric dimethylarginine levels in preeclampsia - Systematic review and meta-analysis.
Topics: Arginine; Biomarkers; Female; Humans; Pre-Eclampsia; Pregnancy | 2018 |
The Role of Nitric Oxide, ADMA, and Homocysteine in The Etiopathogenesis of Preeclampsia-Review.
Topics: Arginine; Female; Homocysteine; Humans; Nitric Oxide; Pre-Eclampsia; Pregnancy; Signal Transduction | 2019 |
Asymmetric Dimethylarginine: Clinical Significance and Novel Therapeutic Approaches.
Topics: Alzheimer Disease; Animals; Arginine; Cardiovascular Diseases; Diabetes Mellitus; Female; Humans; Hy | 2015 |
The role of nitric oxide synthase inhibition by asymmetric dimethylarginine in the pathophysiology of preeclampsia.
Topics: Arginine; Biomarkers; Endothelium, Vascular; Female; Humans; Nitric Oxide Synthase; Pre-Eclampsia; P | 2010 |
Biomarkers in pre-eclampsia: a novel approach to early detection of the disease.
Topics: Antigens, CD; Arginine; Biomarkers; Endoglin; Female; Galectins; Homocysteine; Humans; Leptin; Pre-E | 2012 |
[Asymmetrical methylarginine (ADMA) as a cardiovascular risk factor: epidemiological and prospective data].
Topics: Adult; Aged; Aged, 80 and over; Animals; Arginine; Arteriosclerosis; Biomarkers; Cardiovascular Dise | 2004 |
Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathway.
Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; | 2004 |
Endogenous inhibitors of nitric oxide and preeclampsia: a review.
Topics: Amidohydrolases; Arginine; Endothelium, Vascular; Female; Humans; Nitric Oxide; Nitric Oxide Synthas | 2006 |
37 other studies available for n(g),n(g')-dimethyl-l-arginine and Edema-Proteinuria-Hypertension Gestosis
| Article | Year |
|---|---|
Maternal serum levels of asymmetric dimethylarginine in normal and preeclamptic pregnancies.
Topics: Adult; Arginine; Case-Control Studies; Cross-Sectional Studies; Female; Fetal Growth Retardation; Hu | 2020 |
Systemic vascular resistance and endogenous inhibitors of nitric oxide synthesis in early- compared to late-onset preeclampsia: preliminary findings.
Topics: Adult; Arginine; Case-Control Studies; Female; Humans; Pre-Eclampsia; Pregnancy; Vascular Resistance | 2017 |
Association of serum asymmetric dimethylarginine, homocysteine, and l-arginine concentrations during early pregnancy with hypertensive disorders of pregnancy.
Topics: Adult; Area Under Curve; Arginine; Biomarkers; Body Mass Index; Case-Control Studies; Female; Gestat | 2017 |
Inverse correlation between maternal plasma asymmetric dimethylarginine (ADMA) and birthweight percentile in women with impaired placental perfusion: circulating ADMA as an NO-independent indicator of fetal growth restriction?
Topics: Adult; Arginine; Biomarkers; Birth Weight; Female; Fetal Growth Retardation; Fetus; Gestational Age; | 2018 |
Estimation of asymmetric dimethylarginine (ADMA), placental growth factor (PLGF) and pentraxin 3 (PTX 3) in women with preeclampsia.
Topics: Adult; Arginine; Biomarkers; C-Reactive Protein; Case-Control Studies; Disease Progression; Female; | 2018 |
The ameliorative effect of angiotensin 1-7 on experimentally induced-preeclampsia in rats: Targeting the role of peroxisome proliferator-activated receptors gamma expression & asymmetric dimethylarginine.
Topics: Angiotensin I; Animals; Arginine; Blood Pressure; Female; Oxidative Stress; Peptide Fragments; Place | 2019 |
A comparison of maternal serum levels of endothelial nitric oxide synthase, asymmetric dimethylarginine, and homocysteine in normal and preeclamptic pregnancies.
Topics: Adult; Arginine; Case-Control Studies; Female; Homocysteine; Humans; Nitric Oxide Synthase Type III; | 2013 |
L-arginine metabolism in early-onset and late-onset pre-eclamptic pregnancies.
Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Female; Fetal Blood; Humans; omega-N-Methylargini | 2013 |
Assessment of L-arginine asymmetric 1 dimethyl (ADMA) in early-onset and late-onset (severe) preeclampsia.
Topics: Arginine; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Nitric Oxide; Pre | 2013 |
The relation of maternal serum eNOS, NOSTRIN and ADMA levels with aetiopathogenesis of preeclampsia and/or intrauterine fetal growth restriction.
Topics: Adaptor Proteins, Signal Transducing; Adult; Arginine; Case-Control Studies; DNA-Binding Proteins; F | 2015 |
First-Trimester Maternal Serum Levels of sFLT1, PGF and ADMA Predict Preeclampsia.
Topics: Adult; Area Under Curve; Arginine; Blood Pressure; Case-Control Studies; Demography; Female; Follow- | 2015 |
Serial determinations of asymmetric dimethylarginine and homocysteine during pregnancy to predict pre-eclampsia: a longitudinal study.
Topics: Adult; Arginine; Biomarkers; Body Mass Index; Female; Folic Acid; Follow-Up Studies; Homocysteine; H | 2015 |
[Interactions between markers of endothelial damage (homocysteine and asymmetric dimethylarginine) and antioxidants and B-vitamins in preeclamptic women].
Topics: Adolescent; Adult; Antioxidants; Arginine; Biomarkers; Cross-Sectional Studies; Female; Homocysteine | 2015 |
N-Acetylcysteine Prevents Programmed Hypertension in Male Rat Offspring Born to Suramin-Treated Mothers.
Topics: Acetylcysteine; Animals; Arginine; Blood Pressure; Female; Fetal Development; Hydrogen Sulfide; Hype | 2016 |
Endothelin 1, ADMA and SDMA in pregnancies with obstetric and thrombotic antiphospholipid syndrome.
Topics: Adult; Antiphospholipid Syndrome; Arginine; Chronic Disease; Endothelin-1; Endothelium, Vascular; Fe | 2016 |
Prediction of pre-eclampsia combining NGAL and other biochemical markers with Doppler in the first and/or second trimester of pregnancy. A pilot study.
Topics: Adult; Arginine; Biomarkers; Female; Humans; Lipocalin-2; Matrix Metalloproteinase 9; Pilot Projects | 2016 |
[Relationship between changes of endogenous nitric oxide synthase inhibitor and hydrolase and initiation of pre-eclampsia].
Topics: Adult; Amidohydrolases; Arginine; Chromatography, High Pressure Liquid; Female; Humans; Nitric Oxide | 2009 |
Asymmetric dimethylarginine in the maternal and fetal circulation in preeclampsia.
Topics: Adult; Arginine; Female; Fetus; Humans; Infant, Newborn; Maternal-Fetal Exchange; Nitric Oxide; Pre- | 2009 |
Association of homocysteine, asymmetric dimethylarginine, and nitric oxide with preeclampsia.
Topics: Arginine; Biomarkers; Case-Control Studies; Chromatography, Liquid; Endothelium-Dependent Relaxing F | 2010 |
Interethnic differences in ADMA concentrations and negative association with nitric oxide formation in preeclampsia.
Topics: Adult; Arginine; Biomarkers; Black People; Case-Control Studies; Ethnicity; Female; Humans; Nitric O | 2010 |
Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and plasma concentrations of asymmetric dimethylarginine in Turkish pre-eclamptic women without fetal growth retardation.
Topics: Adult; Analysis of Variance; Arginine; Chromatography, High Pressure Liquid; Female; Fetal Growth Re | 2010 |
Asymmetric dimethylarginine in normotensive pregnant women with isolated fetal intrauterine growth restriction: a comparison with preeclamptic women with and without intrauterine growth restriction.
Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Female; Fetal Growth Retardation; Humans; Pre-Ecl | 2011 |
Levels of asymmetric dimethylarginine throughout normal pregnancy and in pregnancies complicated with preeclampsia or had a small for gestational age baby.
Topics: Adult; Arginine; Blood Chemical Analysis; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; F | 2012 |
The role of asymmetric dimethyl arginine and oxidant/antioxidant system in preeclampsia.
Topics: Adult; Antioxidants; Arginine; Case-Control Studies; Citrulline; Female; Fetal Blood; Humans; Lipid | 2011 |
Asymmetric dimethylarginine, arginine and homoarginine at 11-13 weeks' gestation and preeclampsia: a case-control study.
Topics: Adult; Arginine; Case-Control Studies; Female; Gas Chromatography-Mass Spectrometry; Homoarginine; H | 2013 |
The role of homocysteine, asymmetric dimethylarginine and nitric oxide in pre-eclampsia.
Topics: Adult; Arginine; Case-Control Studies; Female; Homocysteine; Humans; Nitric Oxide; Pre-Eclampsia; Pr | 2012 |
Nitric oxide and carbon monoxide production and metabolism in preeclampsia.
Topics: Adult; Amidohydrolases; Arginine; Biomarkers; Blotting, Western; Carbon Monoxide; Case-Control Studi | 2013 |
Feto-placental nitric oxide, asymmetric dimethylarginine and vascular endothelial growth factor (VEGF) levels and VEGF gene polymorphisms in severe preeclampsia.
Topics: Adolescent; Adult; Arginine; Case-Control Studies; Female; Fetal Blood; Genetic Predisposition to Di | 2013 |
Differences in the association between maternal serum homocysteine and ADMA levels in women with pregnancies complicated by preeclampsia and/or intrauterine growth restriction.
Topics: Adult; Arginine; Case-Control Studies; Female; Fetal Growth Retardation; Homocysteine; Humans; Pre-E | 2013 |
Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia.
Topics: Arginine; Brachial Artery; Endothelium, Vascular; Female; Humans; Placental Circulation; Pre-Eclamps | 2003 |
Plasma concentrations of asymmetric dimethylarginine (ADMA) in Colombian women with pre-eclampsia.
Topics: Adult; Arginine; Case-Control Studies; Colombia; Female; Humans; Pre-Eclampsia; Pregnancy | 2004 |
Concentrations of homocysteine, related metabolites and asymmetric dimethylarginine in preeclamptic women with poor nutritional status.
Topics: Adult; Arginine; Female; Homocysteine; Humans; Nutritional Status; Pre-Eclampsia; Pregnancy; Time Fa | 2005 |
Elevated asymmetric dimethylarginine concentrations precede clinical preeclampsia, but not pregnancies with small-for-gestational-age infants.
Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Female; Humans; Infant, Newborn; Infant, Small fo | 2008 |
First-trimester uterine artery resistance and maternal serum concentration of asymmetric dimethylarginine.
Topics: Adult; Arginine; Arteries; Blood Pressure; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy Trime | 2008 |
Plasma concentrations of endogenous inhibitor of nitric oxide synthesis in normal pregnancy and pre-eclampsia.
Topics: Animals; Arginine; Female; Humans; Hypertension; Nitric Oxide; Pre-Eclampsia; Pregnancy; Pregnancy C | 1993 |
Effect of asymmetric dimethyl arginine on nitric oxide synthase activity in normal and pre-eclamptic placentae.
Topics: Arginine; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Nitric Oxide Synthase; Placenta; P | 1995 |
Levels of dimethylarginines and cytokines in mild and severe preeclampsia.
Topics: Arginine; Blood Pressure; Cytokines; Female; Gestational Age; Humans; Nitric Oxide Synthase; Pre-Ecl | 2001 |