n(g),n(g')-dimethyl-l-arginine has been researched along with Diabetes Mellitus, Type 1 in 18 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to evaluate asymmetric dimethylarginine levels in young patients with Type 1 diabetes mellitus according to diabetes duration and to examine the relationship between these levels and measures of atherosclerosis and myocardial function." | 7.88 | Asymmetric dimethylarginine levels and diabetes duration: Relationship with measures of subclinical atherosclerosis and cardiac function in children and adolescents with Type 1 diabetes. ( Çetin, M; Coşkun, Ş; Eroğlu, N; Ersoy, B; Onur, E; Özkol, M, 2018) |
| "Sixty-one young people with Type 1 diabetes without macrovascular disease or nephropathy and 62 healthy volunteers underwent brachial artery flow-mediated dilatation (FMD) and assay of plasma ADMA and adhesion molecules." | 5.35 | A study of endothelial function and circulating asymmetric dimethylarginine levels in people with Type 1 diabetes without macrovascular disease or microalbuminuria. ( Agarwal, SC; Böger, RH; Home, PD; Lüneburg, N; Schwedhelm, E; Sibal, L, 2009) |
| "The aim of the present study was to investigate plasma levels of asymmetric dimethylarginine (ADMA), an important endogenous inhibitor of nitric oxide synthase, in populations at high risk for atherosclerosis as compared to healthy controls, and furthermore to evaluate the effect of cholesterol lowering therapy in individuals with hypercholesterolemia." | 5.10 | Increased levels of asymmetric dimethylarginine in populations at risk for atherosclerotic disease. Effects of pravastatin. ( Arnesen, H; Eid, HM; Eritsland, J; Larsen, J; Seljeflot, I, 2003) |
| "We aimed to evaluate asymmetric dimethylarginine levels in young patients with Type 1 diabetes mellitus according to diabetes duration and to examine the relationship between these levels and measures of atherosclerosis and myocardial function." | 3.88 | Asymmetric dimethylarginine levels and diabetes duration: Relationship with measures of subclinical atherosclerosis and cardiac function in children and adolescents with Type 1 diabetes. ( Çetin, M; Coşkun, Ş; Eroğlu, N; Ersoy, B; Onur, E; Özkol, M, 2018) |
| "Patients with type I diabetes mellitus (T1DM) have increased incidence of atherosclerosis and cardiovascular disease." | 1.46 | Osteoprotegerin, RANKL, ADMA, and Fetuin-A serum levels in children with type I diabetes mellitus. ( Chrysis, D; Efthymiadou, A; Kritikou, D; Mermigka, A; Spiliotis, BE, 2017) |
| "A total of 341 type 1 and type 2 diabetes patients with variable degree of kidney disease were included at baseline." | 1.38 | ADMA, SDMA and L-arginine/ADMA ratio but not DDAH genetic polymorphisms are reliable predictors of diabetic nephropathy progression as identified by competing risk analysis. ( Bartáková, V; Bělobrádková, J; Jurajda, M; Kaňková, K; Klepárník, M; Krusová, D; Kuricová, K; Malúšková, D; Mužík, J; Olšovský, J; Pácal, L; Pavlík, T; Rehořová, J; Stěpánková, S; Svojanovský, J; Tanhäuserová, V; Tomandl, J, 2012) |
| "Data concerning ADMA level in type 1 diabetes (DM1) are controversial." | 1.36 | [Asymmetric dimethylarginine (ADMA) in children with diabetes type 1]. ( Bossowski, A; Florys, B; Głowińska-Olszewska, B; Jabłońska, J; Luczyński, W; Otocka, A, 2010) |
| "Type 1 diabetes has a bad prognosis concerning the pathogenesis of cardiovascular diseases (CVD)." | 1.35 | Elevated plasma adiponectin and decreased plasma homocysteine and asymmetric dimethylarginine in children with type 1 diabetes. ( Heilman, K; Kool, P; Tillmann, V; Zilmer, K; Zilmer, M, 2009) |
| "Sixty-one young people with Type 1 diabetes without macrovascular disease or nephropathy and 62 healthy volunteers underwent brachial artery flow-mediated dilatation (FMD) and assay of plasma ADMA and adhesion molecules." | 1.35 | A study of endothelial function and circulating asymmetric dimethylarginine levels in people with Type 1 diabetes without macrovascular disease or microalbuminuria. ( Agarwal, SC; Böger, RH; Home, PD; Lüneburg, N; Schwedhelm, E; Sibal, L, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 9 (50.00) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Xiong, Y | 1 |
| He, YL | 1 |
| Li, XM | 1 |
| Nie, F | 1 |
| Zhou, XK | 1 |
| Ersoy, B | 1 |
| Eroğlu, N | 1 |
| Çetin, M | 1 |
| Onur, E | 1 |
| Özkol, M | 1 |
| Coşkun, Ş | 1 |
| Abd El Dayem, SM | 1 |
| Battah, AA | 1 |
| El-Shehaby, A | 1 |
| El Bohy, Ael M | 1 |
| Krebs, A | 1 |
| Doerfer, J | 1 |
| Grünert, SC | 1 |
| Wöhrl, J | 1 |
| Stier, B | 1 |
| Schmidt-Trucksäss, A | 1 |
| Lichte, K | 1 |
| Winkler, K | 1 |
| Grulich-Henn, J | 1 |
| Holder, M | 1 |
| Schwab, KO | 1 |
| Takaya, J | 1 |
| Tanabe, Y | 1 |
| Kuroyanagi, Y | 1 |
| Kaneko, K | 1 |
| Chrysis, D | 1 |
| Efthymiadou, A | 1 |
| Mermigka, A | 1 |
| Kritikou, D | 1 |
| Spiliotis, BE | 1 |
| Heilman, K | 1 |
| Zilmer, M | 1 |
| Zilmer, K | 1 |
| Kool, P | 1 |
| Tillmann, V | 1 |
| Sibal, L | 1 |
| Agarwal, SC | 1 |
| Schwedhelm, E | 1 |
| Lüneburg, N | 1 |
| Böger, RH | 1 |
| Home, PD | 1 |
| Pitocco, D | 1 |
| Zaccardi, F | 1 |
| Di Stasio, E | 1 |
| Romitelli, F | 1 |
| Martini, F | 1 |
| Scaglione, GL | 1 |
| Speranza, D | 1 |
| Santini, S | 1 |
| Zuppi, C | 1 |
| Ghirlanda, G | 1 |
| Huemer, M | 1 |
| Simma, B | 1 |
| Mayr, D | 1 |
| Mühl, A | 1 |
| Rami, B | 1 |
| Schober, E | 1 |
| Ulmer, H | 1 |
| Zanier, U | 1 |
| Bodamer, OA | 1 |
| Głowińska-Olszewska, B | 1 |
| Luczyński, W | 1 |
| Jabłońska, J | 1 |
| Otocka, A | 1 |
| Florys, B | 1 |
| Bossowski, A | 1 |
| Marcovecchio, ML | 2 |
| Widmer, B | 2 |
| Turner, C | 1 |
| Dunger, DB | 2 |
| Dalton, RN | 2 |
| Tanhäuserová, V | 1 |
| Tomandl, J | 1 |
| Pácal, L | 1 |
| Klepárník, M | 1 |
| Malúšková, D | 1 |
| Bartáková, V | 1 |
| Kuricová, K | 1 |
| Rehořová, J | 1 |
| Stěpánková, S | 1 |
| Svojanovský, J | 1 |
| Olšovský, J | 1 |
| Bělobrádková, J | 1 |
| Krusová, D | 1 |
| Jurajda, M | 1 |
| Mužík, J | 1 |
| Pavlík, T | 1 |
| Kaňková, K | 1 |
| Eid, HM | 1 |
| Eritsland, J | 1 |
| Larsen, J | 1 |
| Arnesen, H | 1 |
| Seljeflot, I | 1 |
| Boykin, JV | 1 |
| Baylis, C | 1 |
| Yazici, D | 1 |
| Yavuz, DG | 1 |
| Unsalan, S | 1 |
| Toprak, A | 1 |
| Yüksel, M | 1 |
| Deyneli, O | 1 |
| Aydin, H | 1 |
| Tezcan, H | 1 |
| Rollas, S | 1 |
| Akalin, S | 1 |
| Jehlicka, P | 1 |
| Stožický, F | 1 |
| Mayer, O | 1 |
| Varvařovská, J | 1 |
| Racek, J | 1 |
| Trefil, L | 1 |
| Siala, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Dexamethasone Implant on Retinal Nerve Fiber and Optic Disc Morphology in Patients With Diabetic Maculopathy[NCT03927118] | 43 participants (Actual) | Observational | 2018-02-01 | Completed | |||
| Measurements of Endothelial Function by Means of Peripheral Arterial Tonometry in Diabetic Foot Ulcer Patients Undergoing Hyperbaric Oxygen Therapy.[NCT02221466] | 45 participants (Actual) | Observational | 2014-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for n(g),n(g')-dimethyl-l-arginine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Decreased levels of homoarginine and asymmetric dimethylarginine in children with type 1 diabetes: associations with cardiovascular risk factors but no effect by atorvastin.
Topics: Adolescent; Anticholesteremic Agents; Arginine; Atorvastatin; Cardiovascular Diseases; Diabetes Mell | 2015 |
Increased levels of asymmetric dimethylarginine in populations at risk for atherosclerotic disease. Effects of pravastatin.
Topics: Arginine; Arteriosclerosis; Cholesterol, LDL; Diabetes Mellitus, Type 1; Female; Humans; Hypercholes | 2003 |
Hyperbaric oxygen therapy mediates increased nitric oxide production associated with wound healing: a preliminary study.
Topics: Arginine; Chromatography, High Pressure Liquid; Chronic Disease; Diabetes Mellitus, Type 1; Diabetes | 2007 |
Temporal effects of low-dose ACE inhibition on endothelial function in Type 1 diabetic patients.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Arginine; Diabetes Mellitus, Type 1; Dose-Response | 2007 |
Asymmetric dimethylarginine and the effect of folate substitution in children with familial hypercholesterolemia and diabetes mellitus type 1.
Topics: Adolescent; Anticholesteremic Agents; Arginine; Azetidines; Biomarkers; Child; Diabetes Mellitus, Ty | 2009 |
13 other studies available for n(g),n(g')-dimethyl-l-arginine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Endogenous asymmetric dimethylarginine accumulation precipitates the cardiac and mitochondrial dysfunctions in type 1 diabetic rats.
Topics: Acetylcysteine; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus | 2021 |
Asymmetric dimethylarginine levels and diabetes duration: Relationship with measures of subclinical atherosclerosis and cardiac function in children and adolescents with Type 1 diabetes.
Topics: Adolescent; Adult; Arginine; Atherosclerosis; Carotid Intima-Media Thickness; Child; Diabetes Mellit | 2018 |
Asymmetric dimethyl L-arginine, nitric oxide and cardiovascular disease in adolescent type 1 diabetics.
Topics: Adolescent; Arginine; Brachial Artery; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Me | 2014 |
Asymmetric dimethylarginine is negatively correlated with hyperglycemia in children.
Topics: Adolescent; Arginine; Biomarkers; Body Mass Index; Cardiovascular Diseases; Child; Cross-Sectional S | 2015 |
Osteoprotegerin, RANKL, ADMA, and Fetuin-A serum levels in children with type I diabetes mellitus.
Topics: Adolescent; alpha-2-HS-Glycoprotein; Arginine; Biomarkers; Cardiovascular Diseases; Child; Cohort St | 2017 |
Elevated plasma adiponectin and decreased plasma homocysteine and asymmetric dimethylarginine in children with type 1 diabetes.
Topics: Adiponectin; Adolescent; Arginine; C-Reactive Protein; Case-Control Studies; Child; Child, Preschool | 2009 |
A study of endothelial function and circulating asymmetric dimethylarginine levels in people with Type 1 diabetes without macrovascular disease or microalbuminuria.
Topics: Adolescent; Adult; Albuminuria; Arginine; Biomarkers; Brachial Artery; Case-Control Studies; Cell Ad | 2009 |
Role of asymmetric-dimethyl-L-arginine (ADMA) and nitrite/nitrate (NOx) in the pathogenesis of oxidative stress in female subjects with uncomplicated type 1 diabetes mellitus.
Topics: Adult; Arginine; Blood Glucose; Blood Specimen Collection; Cholesterol; Cholesterol, HDL; Cholestero | 2009 |
Low levels of asymmetric dimethylarginine in children with diabetes mellitus type I compared with healthy children.
Topics: Adolescent; Arginine; Child; Child, Preschool; Cross-Sectional Studies; Diabetes Mellitus, Type 1; F | 2011 |
[Asymmetric dimethylarginine (ADMA) in children with diabetes type 1].
Topics: Adolescent; Adult; Arginine; Biomarkers; Child; Comorbidity; Diabetes Mellitus, Type 1; Endothelium, | 2010 |
Asymmetric dimethylarginine in young people with Type 1 diabetes: a paradoxical association with HbA(1c).
Topics: Adolescent; Albuminuria; Arginine; Biomarkers; Blood Glucose; Cardiovascular Diseases; Child; Diabet | 2011 |
ADMA, SDMA and L-arginine/ADMA ratio but not DDAH genetic polymorphisms are reliable predictors of diabetic nephropathy progression as identified by competing risk analysis.
Topics: Adult; Aged; Amidohydrolases; Arginine; Cross-Sectional Studies; Czech Republic; Diabetes Mellitus, | 2012 |
Effect of acute variations of insulin and glucose on plasma concentrations of asymmetric dimethylarginine in young people with Type 1 diabetes.
Topics: Adolescent; Arginine; Biomarkers; Blood Glucose; Creatinine; Diabetes Mellitus, Type 1; Drug Adminis | 2008 |