n(g),n(g')-dimethyl-l-arginine has been researched along with Depressive Disorder, Major in 4 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| ", the global arginine bioavailability ratio (GABR) and related serum amino acids, between MDD patients and non-depressed controls, and between remitted and non-remitted MDD patients." | 1.48 | Global arginine bioavailability ratio is decreased in patients with major depressive disorder. ( Ali-Sisto, T; Honkalampi, K; Koivumaa-Honkanen, H; Lehto, SM; Mäntyselkä, P; Nandania, J; Ruusunen, A; Tolmunen, T; Valkonen-Korhonen, M; Velagapudi, V; Viinamäki, H, 2018) |
| "In 71 in-patients with major depression and 48 healthy controls the Global Arginine Bioavailability Ratio (GABR), arginase activity (arginine/ornithine ratio), the L-arginine/ADMA ratio, ADMA, and SDMA were determined by high-pressure liquid chromatography." | 1.42 | Nitric Oxide-Related Biological Pathways in Patients with Major Depression. ( Amouzadeh-Ghadikolai, O; Baranyi, A; Baranyi, M; Hlade, P; Koppitz, M; Meinitzer, A; Reicht, G; Robier, C; Rothenhäusler, HB; Theokas, S, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ogłodek, EA | 1 |
| Ali-Sisto, T | 1 |
| Tolmunen, T | 1 |
| Viinamäki, H | 1 |
| Mäntyselkä, P | 1 |
| Valkonen-Korhonen, M | 1 |
| Koivumaa-Honkanen, H | 1 |
| Honkalampi, K | 1 |
| Ruusunen, A | 1 |
| Nandania, J | 1 |
| Velagapudi, V | 1 |
| Lehto, SM | 1 |
| Kielstein, H | 1 |
| Suntharalingam, M | 1 |
| Perthel, R | 1 |
| Song, R | 1 |
| Schneider, SM | 1 |
| Martens-Lobenhoffer, J | 1 |
| Jäger, K | 1 |
| Bode-Böger, SM | 1 |
| Kielstein, JT | 1 |
| Baranyi, A | 1 |
| Amouzadeh-Ghadikolai, O | 1 |
| Rothenhäusler, HB | 1 |
| Theokas, S | 1 |
| Robier, C | 1 |
| Baranyi, M | 1 |
| Koppitz, M | 1 |
| Reicht, G | 1 |
| Hlade, P | 1 |
| Meinitzer, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Analisi Dei Marcatori di Stress Ossidativo in Pazienti Affetti da Tumore Della Mammella, Sottoposte a Radioterapia Postoperatoria e Psicoterapia Con Elementi di Musicoterapia[NCT04446624] | 60 participants (Actual) | Interventional | 2018-02-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for n(g),n(g')-dimethyl-l-arginine and Depressive Disorder, Major
| Article | Year |
|---|---|
Evaluation of ADMA, carbonyl groups, CAT and NKA in depressed patients with and without posttraumatic stress disorder.
Topics: Adult; Arginine; Biomarkers; Catalase; Depressive Disorder, Major; Female; Gene Expression Regulatio | 2017 |
Global arginine bioavailability ratio is decreased in patients with major depressive disorder.
Topics: Adult; Aged; Arginine; Biological Availability; Citrulline; Depressive Disorder, Major; Female; Huma | 2018 |
Role of the endogenous nitric oxide inhibitor asymmetric dimethylarginine (ADMA) and brain-derived neurotrophic factor (BDNF) in depression and behavioural changes: clinical and preclinical data in chronic kidney disease.
Topics: Animals; Arginine; Brain-Derived Neurotrophic Factor; Cohort Studies; Cross-Sectional Studies; Depre | 2015 |
Nitric Oxide-Related Biological Pathways in Patients with Major Depression.
Topics: Adult; Arginase; Arginine; Biological Availability; Case-Control Studies; Demography; Depressive Dis | 2015 |