n(g),n(g')-dimethyl-l-arginine has been researched along with Critical Illness in 14 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
Critical Illness: A disease or state in which death is possible or imminent.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The arginine : ADMA ratio in particular is of clinical importance and the restoration of this ratio is expedient to restore several functions that are disturbed during critical illness." | 8.90 | Asymmetric dimethylarginine and critical illness. ( Brinkmann, SJ; Buijs, N; de Boer, MC; van Leeuwen, PA, 2014) |
| "Arginine depletion in critical illness is associated with impairments in microcirculatory blood flow, impaired wound healing, and T-cell dysfunction." | 6.53 | When Is It Appropriate to Use Arginine in Critical Illness? ( Miller, KR; Patel, JJ; Rosenthal, C; Rosenthal, MD, 2016) |
| "Development of multiple organ failure is the most complex problem in critically ill patients, and is associated with a high mortality." | 5.32 | The asymmetrical dimethylarginine (ADMA)-multiple organ failure hypothesis. ( Nijveldt, RJ; Teerlink, T; van Leeuwen, PA, 2003) |
| " The arginine : ADMA ratio in particular is of clinical importance and the restoration of this ratio is expedient to restore several functions that are disturbed during critical illness." | 4.90 | Asymmetric dimethylarginine and critical illness. ( Brinkmann, SJ; Buijs, N; de Boer, MC; van Leeuwen, PA, 2014) |
| "Serum concentrations of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, may contribute to endothelial dysfunction and organ failure in sepsis." | 3.79 | Elevated asymmetric dimethylarginine levels predict short- and long-term mortality risk in critically ill patients. ( Bruensing, J; Buendgens, L; Dückers, H; Koch, A; Kunze, J; Luedde, T; Matthes, M; Tacke, F; Trautwein, C; Weiskirchen, R, 2013) |
| "Arginine depletion in critical illness is associated with impairments in microcirculatory blood flow, impaired wound healing, and T-cell dysfunction." | 2.53 | When Is It Appropriate to Use Arginine in Critical Illness? ( Miller, KR; Patel, JJ; Rosenthal, C; Rosenthal, MD, 2016) |
| "Development of multiple organ failure is the most complex problem in critically ill patients, and is associated with a high mortality." | 1.32 | The asymmetrical dimethylarginine (ADMA)-multiple organ failure hypothesis. ( Nijveldt, RJ; Teerlink, T; van Leeuwen, PA, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mortensen, KM | 1 |
| Itenov, TS | 1 |
| Hansen, MB | 1 |
| Hvid, K | 1 |
| Lundstrøm, LH | 1 |
| Bestle, MH | 1 |
| Koch, A | 1 |
| Weiskirchen, R | 1 |
| Kunze, J | 1 |
| Dückers, H | 1 |
| Bruensing, J | 1 |
| Buendgens, L | 1 |
| Matthes, M | 1 |
| Luedde, T | 1 |
| Trautwein, C | 1 |
| Tacke, F | 1 |
| Brinkmann, SJ | 1 |
| de Boer, MC | 1 |
| Buijs, N | 1 |
| van Leeuwen, PA | 7 |
| Sitar, ME | 1 |
| Kayacelebi, AA | 1 |
| Beckmann, B | 1 |
| Kielstein, JT | 1 |
| Tsikas, D | 1 |
| Ferrigno, A | 1 |
| Di Pasqua, LG | 1 |
| Berardo, C | 1 |
| Richelmi, P | 1 |
| Vairetti, M | 1 |
| Patel, JJ | 1 |
| Miller, KR | 1 |
| Rosenthal, C | 1 |
| Rosenthal, MD | 1 |
| Richir, MC | 2 |
| Ellger, B | 2 |
| Teerlink, T | 6 |
| Siroen, MP | 3 |
| Visser, M | 3 |
| Spreeuwenberg, M | 1 |
| Girbes, AR | 1 |
| van der Hoven, B | 2 |
| van den Berghe, G | 3 |
| Wilhelm, AJ | 1 |
| de Vries, TP | 1 |
| Davids, M | 2 |
| van Hell, AJ | 1 |
| Nijveldt, RJ | 4 |
| Kuik, DJ | 1 |
| Rauwerda, JA | 1 |
| Wouters, PJ | 1 |
| Castillo, L | 1 |
| Al-Khadra, E | 1 |
| Böger, RH | 1 |
4 reviews available for n(g),n(g')-dimethyl-l-arginine and Critical Illness
| Article | Year |
|---|---|
Mortality in critical illness: The impact of asymmetric dimethylarginine on survival-A systematic review and meta-analysis.
Topics: Area Under Curve; Arginine; Cause of Death; Critical Illness; Humans; Intensive Care Units; Quality | 2019 |
Asymmetric dimethylarginine and critical illness.
Topics: Amidohydrolases; Arginine; Critical Illness; Enzyme Inhibitors; Heart Failure; Humans; Intensive Car | 2014 |
Liver plays a central role in asymmetric dimethylarginine-mediated organ injury.
Topics: Animals; Arginine; Biomarkers; Critical Illness; Humans; Liver; Liver Diseases; Multiple Organ Failu | 2015 |
When Is It Appropriate to Use Arginine in Critical Illness?
Topics: Arginine; Critical Care; Critical Illness; Dietary Supplements; Humans | 2016 |
3 trials available for n(g),n(g')-dimethyl-l-arginine and Critical Illness
| Article | Year |
|---|---|
Asymmetric dimethylarginine (ADMA) in human blood: effects of extended haemodialysis in the critically ill patient with acute kidney injury, protein binding to human serum albumin and proteolysis by thermolysin.
Topics: Acute Kidney Injury; Arginine; Critical Illness; Female; Humans; Male; Protein Binding; Proteolysis; | 2015 |
The effect of rosiglitazone on asymmetric dimethylarginine (ADMA) in critically ill patients.
Topics: Aged; Arginine; Critical Illness; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pilot Projec | 2009 |
Modulation of asymmetric dimethylarginine in critically ill patients receiving intensive insulin treatment: a possible explanation of reduced morbidity and mortality?
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Arginine; Critical Illness; Female; Humans; In | 2005 |
7 other studies available for n(g),n(g')-dimethyl-l-arginine and Critical Illness
| Article | Year |
|---|---|
Elevated asymmetric dimethylarginine levels predict short- and long-term mortality risk in critically ill patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Case-Control Studies; Critical Ill | 2013 |
Role of dimethylarginine dimethylaminohydrolase activity in regulation of tissue and plasma concentrations of asymmetric dimethylarginine in an animal model of prolonged critical illness.
Topics: Amidohydrolases; Animals; Arginine; Critical Illness; Kidney; Liver; Male; Multivariate Analysis; Mu | 2012 |
Role of the human erythrocyte in generation and storage of asymmetric dimethylarginine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amino Acids; Arginine; Biological Transport; Blood Prote | 2012 |
Asymmetrical dimethylarginine (ADMA) in critically ill patients: high plasma ADMA concentration is an independent risk factor of ICU mortality.
Topics: Adult; Aged; Analysis of Variance; Arginine; Critical Illness; Cross-Sectional Studies; Enzyme Inhib | 2003 |
The asymmetrical dimethylarginine (ADMA)-multiple organ failure hypothesis.
Topics: Arginine; Critical Illness; Enzyme Inhibitors; Humans; Liver; Multiple Organ Failure; Nitric Oxide | 2003 |
Hyperglycemia, asymmetric dimethylarginine, and patient survival: Dysregulation of complex networks and the metabolic basis of disease.
Topics: Arginine; Critical Illness; Homocysteine; Humans; Insulin; Nitric Oxide Synthase; Signal Transductio | 2005 |
Live and let die: asymmetric dimethylarginine and septic shock.
Topics: Arginine; Critical Illness; Humans; Nitric Oxide; Nitric Oxide Synthase; Shock, Septic | 2006 |