n(g),n(g')-dimethyl-l-arginine has been researched along with Chronic Disease in 52 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated in this double-blind, controlled study whether prolonged intermittent infusion therapy with L-arginine improves the clinical symptoms of patients with intermittent claudication, as compared with the endothelium-independent vasodilator prostaglandin E1, and control patients." | 9.08 | Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease. ( Alexander, K; Bode-Böger, SM; Böger, RH; Creutzig, A; Frölich, JC; Thiele, W, 1998) |
| "The arginine metabolism balance is of vital importance during the pathogenesis and progression of chronic asthma." | 8.02 | Dysregulated Arginine Metabolism in Young Patients with Chronic Persistent Asthma and in Human Bronchial Epithelial Cells. ( Guo, M; Jiang, GT; Liu, H; Liu, J; She, J; Zhou, B, 2021) |
| "The effects of eicosapentaenoic acid (EPA) on the levels of inflammatory markers, cardiac function and long-term prognosis in chronic heart failure (CHF) patients with dyslipidemia remain unclear." | 7.80 | Effects of eicosapentaenoic acid on the levels of inflammatory markers, cardiac function and long-term prognosis in chronic heart failure patients with dyslipidemia. ( Atarashi, H; Kohashi, K; Kosugi, M; Kusama, Y; Morisawa, T; Nakagomi, A; Saiki, Y; Shimizu, W, 2014) |
| "Altered arginine metabolism, the uncoupling of nitric oxide synthase (NOS) by asymmetric dimethyl-arginine (ADMA), increased oxo-nitrosative stress, and cellular injury were reported in airway epithelial cells in asthma." | 7.77 | Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma. ( Agrawal, A; Ahmad, T; Aich, J; Ghosh, B; Mabalirajan, U; Makhija, L; Sharma, A, 2011) |
| "To investigate the relationship between periodontal disease indexes (PDI) and endothelial dysfunction by means of asymmetric dimethyl-arginine (ADMA) in conditions of both increased and decreased systemic inflammation in the setting of hypertension." | 7.76 | The conjoint detrimental effect of chronic periodontal disease and systemic inflammation on asymmetric dimethyl-arginine in untreated hypertensive subjects. ( Kasiakogias, A; Mostratou, E; Silvestros, S; Soldatos, N; Stefanadi, E; Stefanadis, C; Syrseloudis, D; Thomopoulos, C; Tsioufis, C, 2010) |
| "Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, is elevated in congestive heart failure (CHF) concomitantly with the higher levels of nitric oxide (NO) and cytokines." | 7.72 | High plasma level of asymmetric dimethylarginine in patients with acutely exacerbated congestive heart failure: role in reduction of plasma nitric oxide level. ( Hanada, H; Ishizaka, H; Kamada, T; Matsunaga, T; Okumura, K; Osanai, T; Saitoh, M, 2003) |
| "Hyperhomocysteinemia is associated with an enhanced risk for cardiovascular disease." | 7.72 | Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA. ( Arakawa, N; Bode-Böger, SM; Böger, RH; Hornig, B; Münzel, T; Sydow, K; Tsikas, D, 2004) |
| "Ramipril was given (5 mg daily for 12 weeks), and circulating ADMA, soluble Fas (sFas), myostatin and endothelial function [flow-mediated vasodilation (FMD); ultrasound)] were measured." | 5.36 | Reduced proteinuria using ramipril in diabetic CKD stage 1 decreases circulating cell death receptor activators concurrently with ADMA. A novel pathophysiological pathway? ( Axelsson, J; Caglar, K; Cayci, T; Eyileten, T; Kilic, S; Oguz, Y; Saglam, M; Sonmez, A; Vural, A; Yaman, H; Yenicesu, M; Yilmaz, MI, 2010) |
| "We investigated in this double-blind, controlled study whether prolonged intermittent infusion therapy with L-arginine improves the clinical symptoms of patients with intermittent claudication, as compared with the endothelium-independent vasodilator prostaglandin E1, and control patients." | 5.08 | Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease. ( Alexander, K; Bode-Böger, SM; Böger, RH; Creutzig, A; Frölich, JC; Thiele, W, 1998) |
| "The arginine metabolism balance is of vital importance during the pathogenesis and progression of chronic asthma." | 4.02 | Dysregulated Arginine Metabolism in Young Patients with Chronic Persistent Asthma and in Human Bronchial Epithelial Cells. ( Guo, M; Jiang, GT; Liu, H; Liu, J; She, J; Zhou, B, 2021) |
| "The effects of eicosapentaenoic acid (EPA) on the levels of inflammatory markers, cardiac function and long-term prognosis in chronic heart failure (CHF) patients with dyslipidemia remain unclear." | 3.80 | Effects of eicosapentaenoic acid on the levels of inflammatory markers, cardiac function and long-term prognosis in chronic heart failure patients with dyslipidemia. ( Atarashi, H; Kohashi, K; Kosugi, M; Kusama, Y; Morisawa, T; Nakagomi, A; Saiki, Y; Shimizu, W, 2014) |
| "Altered arginine metabolism, the uncoupling of nitric oxide synthase (NOS) by asymmetric dimethyl-arginine (ADMA), increased oxo-nitrosative stress, and cellular injury were reported in airway epithelial cells in asthma." | 3.77 | Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma. ( Agrawal, A; Ahmad, T; Aich, J; Ghosh, B; Mabalirajan, U; Makhija, L; Sharma, A, 2011) |
| "To investigate the relationship between periodontal disease indexes (PDI) and endothelial dysfunction by means of asymmetric dimethyl-arginine (ADMA) in conditions of both increased and decreased systemic inflammation in the setting of hypertension." | 3.76 | The conjoint detrimental effect of chronic periodontal disease and systemic inflammation on asymmetric dimethyl-arginine in untreated hypertensive subjects. ( Kasiakogias, A; Mostratou, E; Silvestros, S; Soldatos, N; Stefanadi, E; Stefanadis, C; Syrseloudis, D; Thomopoulos, C; Tsioufis, C, 2010) |
| " However, little information is available about any association between plasma levels of asymmetric dimethylarginine (ADMA), insulin resistance, and CAC." | 3.74 | Coronary artery calcification, ADMA, and insulin resistance in CKD patients. ( Hidekazu, M; Ikee, R; Kobayashi, S; Maesato, K; Mano, T; Ohtake, T; Oka, M, 2008) |
| "The rationale of this study is based on the fact that, both proteinuria and elevated asymmetric dimethyl arginine (ADMA) levels have been linked to the progression of vascular disease." | 3.73 | ADMA, proteinuria, and insulin resistance in non-diabetic stage I chronic kidney disease. ( Acikel, C; Bilgi, C; Caglar, K; Cakir, E; Eyileten, T; Kaya, A; Oguz, Y; Oktenli, C; Sonmez, A; Vural, A; Yenicesu, M; Yilmaz, MI; Zoccali, C, 2006) |
| "Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, is elevated in congestive heart failure (CHF) concomitantly with the higher levels of nitric oxide (NO) and cytokines." | 3.72 | High plasma level of asymmetric dimethylarginine in patients with acutely exacerbated congestive heart failure: role in reduction of plasma nitric oxide level. ( Hanada, H; Ishizaka, H; Kamada, T; Matsunaga, T; Okumura, K; Osanai, T; Saitoh, M, 2003) |
| "Hyperhomocysteinemia is associated with an enhanced risk for cardiovascular disease." | 3.72 | Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA. ( Arakawa, N; Bode-Böger, SM; Böger, RH; Hornig, B; Münzel, T; Sydow, K; Tsikas, D, 2004) |
| ") bioavailability and potentially limit atherosclerosis." | 2.71 | Impact of vitamin E on plasma asymmetric dimethylarginine (ADMA) in chronic kidney disease (CKD): a pilot study. ( Abdulhayoglu, E; Barbato, D; Bustami, R; D'Alecy, LG; Desai, A; Handelman, GJ; Novak, JE; Rajagopalan, S; Saran, R; Warren, JS; Weitzel, W, 2003) |
| "Asymmetric dimethylarginine (ADMA) is a naturally occurring amino acid that reduces the bioavailability of nitric oxide." | 2.44 | Asymmetric dimethylarginine: a novel marker of risk and a potential target for therapy in chronic kidney disease. ( Kielstein, JT; Zoccali, C, 2008) |
| "Endothelial dysfunction due to the reduced bioavailability of nitric oxide (NO) is involved in the course of atherosclerotic cardiovascular disease as well as chronic kidney disease (CKD)." | 2.44 | Asymmetric dimethylarginine (ADMA) is a novel emerging risk factor for cardiovascular disease and the development of renal injury in chronic kidney disease. ( Fukami, K; Matsumoto, Y; Okuda, S; Ueda, S; Yamagishi, SI, 2007) |
| "Patients with type 2 diabetes represent 50% of all sudden cardiac deaths." | 1.62 | Lack of evidence of the correlation between plasma Asymmetrical Dimethylarginine correlation and IMT in type 2 diabetic patients with chronic vascular complication. ( Adamiec, R; Dumas, I; Fiodorenko-Dumas, Z; Małecki, R; Paprocka-Borowicz, M; Rabczynski, M, 2021) |
| "Relatively young 109 biopsy-proven IgA nephropathy (IgAN) patients (age: 32." | 1.37 | Association of asymmetric dimethylarginine with severity of kidney injury and decline in kidney function in IgA nephropathy. ( Ando, R; Fujimi-Hayashida, A; Fukami, K; Kaida, Y; Nakayama, Y; Okuda, S; Ueda, S; Yamagishi, S, 2011) |
| "Symmetric dimethylarginine (SDMA) was recently demonstrated to induce reactive oxygen species in monocytes." | 1.37 | Symmetric dimethylarginine as a proinflammatory agent in chronic kidney disease. ( Barreto, DV; Barreto, FC; Eloot, S; Glorieux, G; Liabeuf, S; Massy, Z; Schepers, E; Vanholder, R, 2011) |
| "Ramipril was given (5 mg daily for 12 weeks), and circulating ADMA, soluble Fas (sFas), myostatin and endothelial function [flow-mediated vasodilation (FMD); ultrasound)] were measured." | 1.36 | Reduced proteinuria using ramipril in diabetic CKD stage 1 decreases circulating cell death receptor activators concurrently with ADMA. A novel pathophysiological pathway? ( Axelsson, J; Caglar, K; Cayci, T; Eyileten, T; Kilic, S; Oguz, Y; Saglam, M; Sonmez, A; Vural, A; Yaman, H; Yenicesu, M; Yilmaz, MI, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (3.85) | 18.2507 |
| 2000's | 27 (51.92) | 29.6817 |
| 2010's | 19 (36.54) | 24.3611 |
| 2020's | 4 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, B | 1 |
| Jiang, GT | 1 |
| Liu, H | 1 |
| Guo, M | 1 |
| Liu, J | 1 |
| She, J | 1 |
| Yilmaz, MI | 6 |
| Romano, M | 1 |
| Basarali, MK | 1 |
| Elzagallaai, A | 1 |
| Karaman, M | 1 |
| Demir, Z | 1 |
| Demir, MF | 1 |
| Akcay, F | 1 |
| Seyrek, M | 1 |
| Haksever, N | 1 |
| Piskin, D | 1 |
| Cimaz, R | 1 |
| Rieder, MJ | 1 |
| Demirkaya, E | 2 |
| Fiodorenko-Dumas, Z | 1 |
| Dumas, I | 1 |
| Rabczynski, M | 1 |
| Małecki, R | 1 |
| Adamiec, R | 1 |
| Paprocka-Borowicz, M | 1 |
| Türer Cabbar, A | 1 |
| Değertekin, MM | 1 |
| Şimşek, MA | 1 |
| Özveren, O | 1 |
| Güleç, S | 1 |
| Yanartaş, M | 1 |
| Gezer Taş, S | 1 |
| Olgun Yıldızeli, Ş | 1 |
| Mutlu, B | 1 |
| İşbir, T | 1 |
| Yıldızeli, B | 1 |
| Mangoni, AA | 2 |
| Rodionov, RN | 1 |
| McEvoy, M | 1 |
| Zinellu, A | 1 |
| Carru, C | 1 |
| Sotgia, S | 1 |
| Reimann, M | 1 |
| Hamer, M | 1 |
| Malan, NT | 1 |
| Schlaich, MP | 1 |
| Lambert, GW | 1 |
| Ziemssen, T | 1 |
| Boeger, RH | 1 |
| Malan, L | 1 |
| Kohashi, K | 1 |
| Nakagomi, A | 1 |
| Saiki, Y | 1 |
| Morisawa, T | 1 |
| Kosugi, M | 1 |
| Kusama, Y | 1 |
| Atarashi, H | 1 |
| Shimizu, W | 1 |
| Lüneburg, N | 1 |
| Harbaum, L | 1 |
| Hennigs, JK | 1 |
| Pilz, S | 1 |
| Putz-Bankuti, C | 1 |
| Meinitzer, A | 1 |
| März, W | 1 |
| Kienreich, K | 1 |
| Stojakovic, T | 1 |
| Pieber, TR | 1 |
| Stauber, RE | 1 |
| Mayer-Pickel, K | 1 |
| Kolovetsiou-Kreiner, V | 1 |
| Mörtl, MG | 1 |
| Schlembach, D | 1 |
| Eberhard, K | 1 |
| Obermayer-Pietsch, B | 1 |
| Lang, U | 1 |
| Cervar-Zivkovic, M | 1 |
| Kobayashi, S | 1 |
| Oka, M | 1 |
| Maesato, K | 1 |
| Ikee, R | 1 |
| Mano, T | 1 |
| Hidekazu, M | 1 |
| Ohtake, T | 1 |
| Kato, A | 1 |
| Odamaki, M | 1 |
| Ishida, J | 1 |
| Hishida, A | 1 |
| Nanayakkara, PW | 1 |
| Kiefte-de Jong, JC | 1 |
| ter Wee, PM | 1 |
| Stehouwer, CD | 1 |
| van Ittersum, FJ | 1 |
| Olthof, MR | 1 |
| Teerlink, T | 2 |
| Twisk, JW | 1 |
| van Guldener, C | 1 |
| Smulders, YM | 1 |
| Ueda, S | 4 |
| Matsumoto, Y | 3 |
| Kaida, Y | 2 |
| Okuda, S | 4 |
| Yamagishi, S | 3 |
| Mora-Fernández, C | 1 |
| Jarque, A | 1 |
| Getino, MA | 1 |
| Sánchez, R | 1 |
| Lozano, L | 1 |
| Navarro, JF | 1 |
| Kielstein, JT | 4 |
| Zoccali, C | 7 |
| Vida, G | 1 |
| Sulyok, E | 1 |
| Lakatos, O | 1 |
| Ertl, T | 1 |
| Martens-Lobenhoffer, J | 2 |
| Bode-Böger, SM | 4 |
| Zakrzewicz, D | 1 |
| Eickelberg, O | 1 |
| Tsioufis, C | 1 |
| Thomopoulos, C | 1 |
| Soldatos, N | 1 |
| Syrseloudis, D | 1 |
| Kasiakogias, A | 1 |
| Silvestros, S | 1 |
| Stefanadi, E | 1 |
| Mostratou, E | 1 |
| Stefanadis, C | 1 |
| Paul, B | 1 |
| Whiting, MJ | 1 |
| De Pasquale, CG | 1 |
| David, S | 1 |
| Kümpers, P | 1 |
| Lukasz, A | 1 |
| Fliser, D | 2 |
| Kliem, V | 1 |
| Haller, H | 1 |
| Sonmez, A | 5 |
| Saglam, M | 4 |
| Yaman, H | 2 |
| Cayci, T | 1 |
| Kilic, S | 2 |
| Eyileten, T | 5 |
| Caglar, K | 5 |
| Oguz, Y | 4 |
| Vural, A | 5 |
| Yenicesu, M | 4 |
| Axelsson, J | 3 |
| Ahmad, T | 1 |
| Mabalirajan, U | 1 |
| Sharma, A | 1 |
| Aich, J | 1 |
| Makhija, L | 1 |
| Ghosh, B | 1 |
| Agrawal, A | 1 |
| Fujimi-Hayashida, A | 1 |
| Ando, R | 1 |
| Nakayama, Y | 1 |
| Fukami, K | 3 |
| Lilitkarntakul, P | 1 |
| Dhaun, N | 1 |
| Melville, V | 1 |
| Blackwell, S | 1 |
| Talwar, DK | 1 |
| Liebman, B | 1 |
| Asai, T | 1 |
| Pollock, J | 1 |
| Goddard, J | 1 |
| Webb, DJ | 1 |
| Tsarouhas, K | 1 |
| Karatzaferi, C | 1 |
| Tsitsimpikou, C | 1 |
| Haliassos, A | 1 |
| Kouretas, D | 1 |
| Pavlidis, P | 1 |
| Veskoukis, A | 1 |
| Adamopoulos, S | 1 |
| Kyriakides, Z | 1 |
| Constantinou, L | 1 |
| Koutedakis, Y | 1 |
| Rentoukas, E | 1 |
| Schepers, E | 1 |
| Barreto, DV | 1 |
| Liabeuf, S | 1 |
| Glorieux, G | 1 |
| Eloot, S | 1 |
| Barreto, FC | 1 |
| Massy, Z | 2 |
| Vanholder, R | 1 |
| Grassi, G | 1 |
| Seravalle, G | 1 |
| Ghiadoni, L | 1 |
| Tripepi, G | 1 |
| Bruno, RM | 1 |
| Mancia, G | 1 |
| Baylis, C | 4 |
| Millatt, LJ | 1 |
| Whitley, GS | 1 |
| Li, D | 1 |
| Leiper, JM | 1 |
| Siragy, HM | 1 |
| Carey, RM | 1 |
| Johns, RA | 1 |
| Saitoh, M | 1 |
| Osanai, T | 1 |
| Kamada, T | 1 |
| Matsunaga, T | 1 |
| Ishizaka, H | 1 |
| Hanada, H | 1 |
| Okumura, K | 1 |
| Saran, R | 1 |
| Novak, JE | 1 |
| Desai, A | 1 |
| Abdulhayoglu, E | 1 |
| Warren, JS | 1 |
| Bustami, R | 1 |
| Handelman, GJ | 1 |
| Barbato, D | 1 |
| Weitzel, W | 1 |
| D'Alecy, LG | 1 |
| Rajagopalan, S | 1 |
| Sydow, K | 1 |
| Hornig, B | 1 |
| Arakawa, N | 1 |
| Tsikas, D | 1 |
| Münzel, T | 1 |
| Böger, RH | 2 |
| Siroen, MP | 1 |
| Warlé, MC | 1 |
| Nijveldt, RJ | 1 |
| Kuipers, EJ | 1 |
| Metselaar, HJ | 1 |
| Tilanus, HW | 1 |
| Kuik, DJ | 1 |
| van der Sijp, JR | 1 |
| Meijer, S | 1 |
| van der Hoven, B | 1 |
| van Leeuwen, PA | 1 |
| Cakir, E | 3 |
| Ozgurtas, T | 1 |
| Aydin, A | 1 |
| Ozcan, O | 1 |
| Acikel, C | 2 |
| Tasar, M | 1 |
| Genctoy, G | 1 |
| Erbil, K | 1 |
| Kaya, A | 1 |
| Bilgi, C | 1 |
| Oktenli, C | 1 |
| Matsuguma, K | 1 |
| Shibata, R | 1 |
| Matsuoka, H | 1 |
| Imaizumi, T | 1 |
| Yamagishi, SI | 1 |
| Schiffrin, EL | 1 |
| Lipman, ML | 1 |
| Mann, JF | 1 |
| Boykin, JV | 1 |
| Skoro-Sajer, N | 1 |
| Mittermayer, F | 1 |
| Panzenboeck, A | 1 |
| Bonderman, D | 1 |
| Sadushi, R | 1 |
| Hitsch, R | 1 |
| Jakowitsch, J | 1 |
| Klepetko, W | 1 |
| Kneussl, MP | 1 |
| Wolzt, M | 1 |
| Lang, IM | 1 |
| Stenvinkel, P | 2 |
| Carrero, JJ | 2 |
| Lindholm, B | 2 |
| Heimbürger, O | 1 |
| Qureshi, AR | 1 |
| Cengel, A | 1 |
| Sahinarslan, A | 1 |
| Biberoğlu, G | 1 |
| Hasanoğlu, A | 1 |
| Tavil, Y | 1 |
| Tulmaç, M | 1 |
| Ozdemir, M | 1 |
| Arese, M | 1 |
| Strasly, M | 1 |
| Ruva, C | 1 |
| Costamagna, C | 1 |
| Ghigo, D | 1 |
| MacAllister, R | 1 |
| Verzetti, G | 1 |
| Tetta, C | 1 |
| Bosia, A | 1 |
| Bussolino, F | 1 |
| Thiele, W | 1 |
| Creutzig, A | 1 |
| Alexander, K | 1 |
| Frölich, JC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of an Oxidative-Stress-Reducing Strategy Consisting of Pravastatin, Vitamin E and Homocysteine-Lowering on Carotid Intima-Media Thickness in Patients With Mild-to-Moderate Chronic Kidney Disease[NCT00384618] | Phase 4 | 100 participants | Interventional | 2001-05-31 | Terminated | ||
| Effect of Paricalcitol on Endothelial Function in Chronic Kidney Disease (CKD) Patients (the PENNY Study)[NCT01680198] | Phase 3 | 88 participants (Actual) | Interventional | 2011-06-30 | Completed | ||
| Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease[NCT05719714] | Phase 1/Phase 2 | 60 participants (Anticipated) | Interventional | 2023-11-01 | Recruiting | ||
| Influence of Preoperative Hemodialysis or Intraoperative Modified Ultrafiltration on Postoperative Outcome for Patients With Severe Renal Dysfunction Undergoing Open Heart Surgery: Randomized, Controlled, Multicenter Clinical Trial[NCT00720967] | Phase 3 | 450 participants (Anticipated) | Interventional | 2008-11-30 | Not yet recruiting | ||
| Effect of Beraprost Sodium on Arterial Stiffness in Patients With Type 2 Diabetic Nephropathy (BESTinDN Study)[NCT01796418] | 102 participants (Anticipated) | Interventional | 2013-03-31 | Recruiting | |||
| A Multicenter, Randomized Trial to Compare Xience and Vision Coronary Stents in the Same Multivessel Patient With Chronic Kidney Disease[NCT00818792] | Phase 2 | 215 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| Measurements of Endothelial Function by Means of Peripheral Arterial Tonometry in Diabetic Foot Ulcer Patients Undergoing Hyperbaric Oxygen Therapy.[NCT02221466] | 45 participants (Actual) | Observational | 2014-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
13 reviews available for n(g),n(g')-dimethyl-l-arginine and Chronic Disease
| Article | Year |
|---|---|
New horizons in arginine metabolism, ageing and chronic disease states.
Topics: Aged; Aging; Arginine; Chronic Disease; Homoarginine; Humans | 2019 |
The endothelial ADMA/NO pathway in hypoxia-related chronic respiratory diseases.
Topics: Amidohydrolases; Animals; Arginine; Chronic Disease; Humans; Hypoxia; Nitric Oxide; Respiratory Trac | 2014 |
[Endothelial injury and CKD].
Topics: Animals; Arginine; Cardiovascular Diseases; Chronic Disease; Endothelium, Vascular; Humans; Kidney D | 2008 |
[Novelties in the field of progression factors in chronic kidney disease].
Topics: Adult; Amidohydrolases; Animals; Arginine; Carbon; Cardiovascular Diseases; Chronic Disease; Clinica | 2008 |
Asymmetric dimethylarginine: a novel marker of risk and a potential target for therapy in chronic kidney disease.
Topics: Amidohydrolases; Animals; Arginine; Biomarkers; Chronic Disease; Disease Progression; Genetic Therap | 2008 |
From arginine methylation to ADMA: a novel mechanism with therapeutic potential in chronic lung diseases.
Topics: Arginine; Biomarkers; Chronic Disease; Humans; Lung Diseases; Methylation; Protein Processing, Post- | 2009 |
Nitric oxide synthase derangements and hypertension in kidney disease.
Topics: Amidohydrolases; Animals; Arginine; Chronic Disease; Disease Progression; Humans; Hypertension; Kidn | 2012 |
Biomarkers in chronic kidney disease: utility and issues towards better understanding.
Topics: Animals; Arginine; Biomarkers; C-Reactive Protein; Chronic Disease; Disease Progression; Glomerular | 2005 |
Arginine, arginine analogs and nitric oxide production in chronic kidney disease.
Topics: Absorption; Amidohydrolases; Arginine; Biological Availability; Cardiovascular Diseases; Chronic Dis | 2006 |
Asymmetric dimethylarginine (ADMA) is a novel emerging risk factor for cardiovascular disease and the development of renal injury in chronic kidney disease.
Topics: Arginine; Cardiovascular Diseases; Chronic Disease; Endothelium, Vascular; Humans; Kidney Diseases; | 2007 |
Chronic kidney disease: effects on the cardiovascular system.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker | 2007 |
Chronic kidney disease: effects on the cardiovascular system.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker | 2007 |
Chronic kidney disease: effects on the cardiovascular system.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker | 2007 |
Chronic kidney disease: effects on the cardiovascular system.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker | 2007 |
Chronic kidney disease: effects on the cardiovascular system.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker | 2007 |
Chronic kidney disease: effects on the cardiovascular system.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker | 2007 |
Chronic kidney disease: effects on the cardiovascular system.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker | 2007 |
Chronic kidney disease: effects on the cardiovascular system.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker | 2007 |
Chronic kidney disease: effects on the cardiovascular system.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Atherosclerosis; Biomarker | 2007 |
Nitric oxide deficiency in chronic kidney disease.
Topics: Arginine; Chronic Disease; Humans; Kidney Diseases; Nitric Oxide; Nitric Oxide Synthase | 2008 |
Emerging biomarkers for evaluating cardiovascular risk in the chronic kidney disease patient: how do new pieces fit into the uremic puzzle?
Topics: Albuminuria; Arginine; Cardiovascular Diseases; Chronic Disease; Endothelium, Vascular; Humans; Kidn | 2008 |
7 trials available for n(g),n(g')-dimethyl-l-arginine and Chronic Disease
| Article | Year |
|---|---|
The Effect of Corrected Inflammation, Oxidative Stress and Endothelial Dysfunction on Fmd Levels in Patients with Selected Chronic Diseases: A Quasi-Experimental Study.
Topics: Adult; Aged; Antioxidants; Arginine; Atherosclerosis; C-Reactive Protein; Chronic Disease; Dietary S | 2020 |
Randomized placebo-controlled trial assessing a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on plasma asymmetric dimethylarginine concentration in mild to moderate CKD.
Topics: Adult; Aged; Anticholesteremic Agents; Arginine; Carotid Arteries; Chronic Disease; Creatinine; Doub | 2009 |
Acute effects of 5-methyltetrahydrofolate on endothelial function and asymmetric dimethylarginine in patients with chronic heart failure.
Topics: Aged; Arginine; Chronic Disease; Endothelium, Vascular; Female; Heart Failure; Hemodynamics; Humans; | 2010 |
Effects of walking on heart rate recovery, endothelium modulators and quality of life in patients with heart failure.
Topics: Aged; Analysis of Variance; Arginine; Biomarkers; Chronic Disease; Endothelium, Vascular; Exercise T | 2011 |
Impact of vitamin E on plasma asymmetric dimethylarginine (ADMA) in chronic kidney disease (CKD): a pilot study.
Topics: Adult; Aged; alpha-Tocopherol; Antioxidants; Arginine; Chronic Disease; Female; Humans; Kidney; Kidn | 2003 |
Hyperbaric oxygen therapy mediates increased nitric oxide production associated with wound healing: a preliminary study.
Topics: Arginine; Chromatography, High Pressure Liquid; Chronic Disease; Diabetes Mellitus, Type 1; Diabetes | 2007 |
Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease.
Topics: Aged; Aged, 80 and over; Alprostadil; Arginine; Arterial Occlusive Diseases; Blood Flow Velocity; Ch | 1998 |
32 other studies available for n(g),n(g')-dimethyl-l-arginine and Chronic Disease
| Article | Year |
|---|---|
Dysregulated Arginine Metabolism in Young Patients with Chronic Persistent Asthma and in Human Bronchial Epithelial Cells.
Topics: Adult; Arginine; Asthma; Bronchi; Case-Control Studies; Cell Culture Techniques; Chronic Disease; Ci | 2021 |
Lack of evidence of the correlation between plasma Asymmetrical Dimethylarginine correlation and IMT in type 2 diabetic patients with chronic vascular complication.
Topics: Adult; Aged; Arginine; Atherosclerosis; Carotid Artery, Internal; Carotid Intima-Media Thickness; Ca | 2021 |
Evaluation of Asymmetric Dimethylarginine Levels in Patients With Chronic Thromboembolic Pulmonary Hypertension Undergoing Pulmonary Endarterectomy.
Topics: Arginine; Chronic Disease; Endarterectomy; Humans; Hypertension, Pulmonary | 2022 |
Effects of acute and chronic stress on the L-arginine nitric oxide pathway in black and white South Africans: the sympathetic activity and ambulatory blood pressure in Africans study.
Topics: Acute Disease; Adult; Arginine; Black People; Blood Pressure; Blood Pressure Monitoring, Ambulatory; | 2013 |
Effects of eicosapentaenoic acid on the levels of inflammatory markers, cardiac function and long-term prognosis in chronic heart failure patients with dyslipidemia.
Topics: Aged; Arginine; Biomarkers; Chemokine CCL2; Chromatography, High Pressure Liquid; Chronic Disease; D | 2014 |
Association of homoarginine and methylarginines with liver dysfunction and mortality in chronic liver disease.
Topics: Adult; Aged; Arginine; Chronic Disease; Disease-Free Survival; Female; Follow-Up Studies; Homoargini | 2015 |
Endothelin 1, ADMA and SDMA in pregnancies with obstetric and thrombotic antiphospholipid syndrome.
Topics: Adult; Antiphospholipid Syndrome; Arginine; Chronic Disease; Endothelin-1; Endothelium, Vascular; Fe | 2016 |
Coronary artery calcification, ADMA, and insulin resistance in CKD patients.
Topics: Aged; Arginine; Calcinosis; Case-Control Studies; Chronic Disease; Coronary Angiography; Coronary Ar | 2008 |
Relationship between serum pre-B cell colony-enhancing factor/visfatin and atherosclerotic parameters in chronic hemodialysis patients.
Topics: Aged; Aorta; Arginine; Arteries; Atherosclerosis; B-Lymphocytes; Body Mass Index; C-Reactive Protein | 2009 |
Plasma levels of asymmetric dimethylarginine in premature neonates: its possible involvement in developmental programming of chronic diseases.
Topics: Arginine; Cardiovascular Diseases; Chronic Disease; Diabetes Mellitus, Type 2; Female; Humans; Infan | 2009 |
The conjoint detrimental effect of chronic periodontal disease and systemic inflammation on asymmetric dimethyl-arginine in untreated hypertensive subjects.
Topics: Arginine; Chronic Disease; Cross-Sectional Studies; Female; Humans; Hypertension; Inflammation; Male | 2010 |
Circulating angiopoietin-2 levels increase with progress of chronic kidney disease.
Topics: Adult; Aged; Angiopoietin-2; Arginine; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Ch | 2010 |
Reduced proteinuria using ramipril in diabetic CKD stage 1 decreases circulating cell death receptor activators concurrently with ADMA. A novel pathophysiological pathway?
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Arginine; Chronic Disease; Diabetic Nephropat | 2010 |
Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma.
Topics: Airway Remodeling; Animals; Arginine; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Flui | 2011 |
FGF-23 and vascular dysfunction in patients with stage 3 and 4 chronic kidney disease.
Topics: Adult; Arginine; Chronic Disease; Female; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fo | 2010 |
Do sea stars have low ADMA levels? High ADMA and low EPC count--duo infernal for the kidney.
Topics: Animals; Arginine; Cell Count; Chronic Disease; Endothelial Cells; Glomerular Filtration Rate; Human | 2010 |
Association of asymmetric dimethylarginine with severity of kidney injury and decline in kidney function in IgA nephropathy.
Topics: Adult; Arginine; Case-Control Studies; Chronic Disease; Cross-Sectional Studies; Female; Glomerular | 2011 |
Blood pressure and not uraemia is the major determinant of arterial stiffness and endothelial dysfunction in patients with chronic kidney disease and minimal co-morbidity.
Topics: Adult; Analysis of Variance; Arginine; Biomarkers; Blood Pressure; Brachial Artery; C-Reactive Prote | 2011 |
Symmetric dimethylarginine as a proinflammatory agent in chronic kidney disease.
Topics: Acetylcysteine; Aged; Aged, 80 and over; Arginine; Belgium; Biomarkers; Case-Control Studies; Cell L | 2011 |
Sympathetic nerve traffic and asymmetric dimethylarginine in chronic kidney disease.
Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Chronic Disease; Cross-Sectional Studies; Disease Pro | 2011 |
Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension.
Topics: Amidohydrolases; Animals; Arginine; Blotting, Western; Chronic Disease; Disease Models, Animal; Enzy | 2003 |
High plasma level of asymmetric dimethylarginine in patients with acutely exacerbated congestive heart failure: role in reduction of plasma nitric oxide level.
Topics: Acute Disease; Arginine; Chromatography, High Pressure Liquid; Chronic Disease; Cytokines; Enzyme In | 2003 |
Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Arterial Occlusive Diseases; Chronic Disease; Endothelium, | 2004 |
The transplanted liver graft is capable of clearing asymmetric dimethylarginine.
Topics: Acute Disease; Arginine; Biomarkers; Case-Control Studies; Chronic Disease; Graft Rejection; Humans; | 2004 |
The determinants of endothelial dysfunction in CKD: oxidative stress and asymmetric dimethylarginine.
Topics: Adult; Arginine; Brachial Artery; Cardiovascular Diseases; Chronic Disease; Copper; Endothelium, Vas | 2006 |
ADMA, proteinuria, and insulin resistance in non-diabetic stage I chronic kidney disease.
Topics: Adult; Arginine; Biomarkers; C-Reactive Protein; Case-Control Studies; Chronic Disease; Disease Prog | 2006 |
Dimethylarginine dimethylaminohydrolase prevents progression of renal dysfunction by inhibiting loss of peritubular capillaries and tubulointerstitial fibrosis in a rat model of chronic kidney disease.
Topics: Amidohydrolases; Animals; Arginine; Capillaries; Chronic Disease; Disease Models, Animal; Disease Pr | 2007 |
A new perspective for the treatment of renal diseases?
Topics: Amidohydrolases; Arginine; Cardiovascular Diseases; Chronic Disease; Humans; Kidney Diseases; Nitric | 2007 |
Asymmetric dimethylarginine is increased in chronic thromboembolic pulmonary hypertension.
Topics: Aged; Arginine; Chronic Disease; Endothelial Cells; Enzyme Inhibitors; Female; Humans; Hypertension, | 2007 |
ADMA levels correlate with proteinuria, secondary amyloidosis, and endothelial dysfunction.
Topics: Adult; Amyloidosis; Arginine; Chronic Disease; Endothelium; Female; Glomerulonephritis; Humans; Male | 2008 |
Asymmetrical dimethylarginine level in atrial fibrillation.
Topics: Acute Disease; Arginine; Atrial Fibrillation; Chromatography, High Pressure Liquid; Chronic Disease; | 2008 |
Regulation of nitric oxide synthesis in uraemia.
Topics: Analysis of Variance; Animals; Arginine; Chronic Disease; Dialysis Solutions; Endothelium, Vascular; | 1995 |