Page last updated: 2024-10-17

n(g),n(g')-dimethyl-l-arginine and Carotid Artery Diseases

n(g),n(g')-dimethyl-l-arginine has been researched along with Carotid Artery Diseases in 25 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Carotid Artery Diseases: Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.

Research Excerpts

ExcerptRelevanceReference
"This study was to assess the relationship between asymmetric dimethylarginine (ADMA) and carotid atherosclerosis in patients with essential hypertension."7.81Asymmetric dimethylarginine is associated with carotid atherosclerosis in patients with essential hypertension. ( Wang, X; Xia, W; Xu, L; Xu, W; Yao, Y, 2015)
"Osteoprotegerin (OPG) is a soluble glycoprotein belonging to the tumor necrosis factor receptor superfamily and is linked to vascular atherosclerosis and calcification."5.42Osteoprotegerin is Associated With Endothelial Function and Predicts Early Carotid Atherosclerosis in Patients With Coronary Artery Disease. ( Atarashi, H; Kohashi, K; Kosugi, M; Kusama, Y; Morisawa, T; Nakagomi, A; Shimizu, W, 2015)
"Non-alcoholic fatty liver disease (NAFLD) is associated with cardiovascular disease."5.38Elevated asymmetric dimethylarginine in plasma: an early marker for endothelial dysfunction in non-alcoholic fatty liver disease? ( Aslan, F; Bagci, S; Dogru, T; Ercin, CN; Genc, H; Kara, M; Kurt, I; Ors, F; Sertoglu, E; Sonmez, A; Tapan, S, 2012)
"This study was to assess the relationship between asymmetric dimethylarginine (ADMA) and carotid atherosclerosis in patients with essential hypertension."3.81Asymmetric dimethylarginine is associated with carotid atherosclerosis in patients with essential hypertension. ( Wang, X; Xia, W; Xu, L; Xu, W; Yao, Y, 2015)
" Patients with metabolic syndrome (MS) had lower activity of gluthatione peroxidase, higher asymmetric dimethyloarginine (ADMA) and oxidized LDL cholesterol (oxyLDL) in comparison to patients without MS."3.78Oxidative stress in hypertensive children before and after 1 year of antihypertensive therapy. ( Janas, R; Litwin, M; Niemirska, A; Płudowski, P; Skorupa, E; Sladowska-Kozłowska, J; Wawer, ZT; Wierzbicka, A, 2012)
"This research is aimed at studying the predictors of the IMT of CCA among basic atherogenic risk biomarkers - lipid [total cholesterol (TC), triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein (LDL) cholesterol, Apolipoprotein-B, Apolipoprotein-Ai, Apolipoprotein-B/A(1) index] and non-lipid, [asymmetric dimethylarginine (ADMA), total homocysteine, cell adhesion molecules] in asymptomatic subjects with newly detected severe hypercholesterolemia."3.76Predictors of the intima-media thickness of carotid artery in asymptomatic newly detected severe hypercholesterolemic patients. ( Deneva, T; Marinov, B; Vladimirova-Kitova, L, 2010)
"We investigated whether the eNOS G/T polymorphism (Glu298Asp variant) is linked to the severity of carotid atherosclerosis and whether it is independent of asymmetric dimethylarginine (ADMA) in determining vascular damage in patients with end-stage renal disease (ESRD)."3.73Atherosclerosis and the Glu298Asp polymorphism of the eNOS gene in white patients with end-stage renal disease. ( Benedetto, FA; Boeger, RH; Maas, R; Mallamaci, F; Parlongo, RM; Pisano, A; Spoto, B; Testa, A; Tripepi, G; Zoccali, C, 2005)
"The serum ADMA may be related to ischaemic stroke, and it is a risk factor for carotid atherosclerosis."2.72A systematic review of the correlation between serum asymmetric dimethylarginine, carotid atherosclerosis and ischaemic stroke. ( Chen, Y; Huang, Q; Qin, Z; Tang, L; Tang, X; Zhong, W, 2021)
"Carotid atherosclerosis was evaluated by ultrasonographically determined intima-media thickness (IMT)."1.42Asymmetric dimethylarginine is associated with high-sensitivity C-reactive protein and early carotid atherosclerosis in women with previous gestational diabetes mellitus. ( Li, D; Shao, Y; Xia, W; Xu, L; Xu, W; Zhang, C, 2015)
"Osteoprotegerin (OPG) is a soluble glycoprotein belonging to the tumor necrosis factor receptor superfamily and is linked to vascular atherosclerosis and calcification."1.42Osteoprotegerin is Associated With Endothelial Function and Predicts Early Carotid Atherosclerosis in Patients With Coronary Artery Disease. ( Atarashi, H; Kohashi, K; Kosugi, M; Kusama, Y; Morisawa, T; Nakagomi, A; Shimizu, W, 2015)
"Asymmetric dimethylarginine (ADMA) is an endogenous nitric oxide synthase (NOS) inhibitor known as a mediator of endothelial dysfunction and atherosclerosis."1.40ADMA/SDMA in elderly subjects with asymptomatic carotid atherosclerosis: values and site-specific association. ( Bucciarelli, T; D'Orazio, N; Gallina, S; Riccioni, G; Scotti, L; Speranza, L; Speziale, G, 2014)
"Nonalcoholic fatty liver disease (NAFLD), a hepatic manifestation of metabolic syndrome (MetS) is closely associated with an increased risk of cardiovascular disease."1.39Plasma fetuin-A is associated with endothelial dysfunction and subclinical atherosclerosis in subjects with nonalcoholic fatty liver disease. ( Aslan, F; Bagci, S; Dogru, T; Ercin, CN; Genc, H; Kara, M; Karslioglu, Y; Kurt, I; Ors, F; Sertoglu, E; Sonmez, A; Tapan, S, 2013)
"Non-alcoholic fatty liver disease (NAFLD) is associated with cardiovascular disease."1.38Elevated asymmetric dimethylarginine in plasma: an early marker for endothelial dysfunction in non-alcoholic fatty liver disease? ( Aslan, F; Bagci, S; Dogru, T; Ercin, CN; Genc, H; Kara, M; Kurt, I; Ors, F; Sertoglu, E; Sonmez, A; Tapan, S, 2012)
"Insulin resistance was quantified by Homeostasis Model Assessment index."1.38Biological signatures of asymptomatic extra- and intracranial atherosclerosis: the Barcelona-AsIA (Asymptomatic Intracranial Atherosclerosis) study. ( Alzamora, MT; Arenillas, JF; Barallat, J; Dávalos, A; Dorado, L; Galán, A; Hernández, M; Jiménez, M; López-Cancio, E; Massuet, A; Millán, M; Reverté, S; Suñol, A, 2012)
"Carotid atherosclerosis was determined by ultrasonographically evaluated intima- media thickness (IMT) and plaque score."1.38Asymmetric dimethylarginine and carotid atherosclerosis in Type 2 diabetes mellitus. ( Chi, Y; Shao, Y; Wang, X; Wang, Y; Xia, W, 2012)
" L-arginine is independently associated with abnormal pulsatile (but not resistive) arterial hemodynamic indices, which may reflect abnormal L-arginine transport, leading to decreased intracellular bioavailability for NO synthesis."1.35Endogenous nitric oxide synthase inhibitors, arterial hemodynamics, and subclinical vascular disease: the PREVENCION Study. ( Bralley, JA; Chirinos, JA; Chirinos-Pacheco, J; Corrales-Medina, F; Cuba-Bustinza, C; David, R; Medina-Lezama, J; Muñoz-Atahualpa, E; Zea-Díaz, H, 2008)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (32.00)29.6817
2010's16 (64.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Qin, Z1
Tang, L1
Huang, Q1
Chen, Y2
Zhong, W1
Tang, X1
Dirajlal-Fargo, S1
El Kamari, V1
Sattar, A1
Alam, K1
Funderburg, N1
Labbato, D1
Pirro, L1
Longenecker, CT1
Wilson, WH1
McComsey, GA1
Riccioni, G1
Scotti, L1
D'Orazio, N1
Gallina, S1
Speziale, G1
Speranza, L1
Bucciarelli, T1
Xia, W3
Li, D1
Zhang, C1
Xu, L2
Xu, W2
Shao, Y2
Wang, X2
Yao, Y1
Burgner, DP1
Sabin, MA1
Magnussen, CG1
Cheung, M1
Sun, C1
Kähönen, M1
Hutri-Kähönen, N1
Lehtimäki, T1
Jokinen, E1
Laitinen, T1
Viikari, JS1
Raitakari, OT2
Juonala, M1
Kocyigit, I1
Unal, A1
Gungor, O1
Orscelik, O1
Eroglu, E1
Dogan, E1
Sen, A1
Yasan, M1
Hayri Sipahioglu, M1
Tokgoz, B1
Dogan, A1
Oymak, O1
Menghini, R1
Casagrande, V1
Cardellini, M1
Ballanti, M1
Davato, F1
Cardolini, I1
Stoehr, R1
Fabrizi, M1
Morelli, M1
Anemona, L1
Bernges, I1
Schwedhelm, E1
Ippoliti, A1
Mauriello, A1
Böger, RH1
Federici, M1
Morisawa, T1
Nakagomi, A1
Kohashi, K1
Kosugi, M1
Kusama, Y1
Atarashi, H1
Shimizu, W1
Sun, L1
Bai, Y1
Zhao, R1
Sun, T1
Cao, R1
Wang, F1
He, G1
Zhang, W1
Ye, P1
Du, G1
Chirinos, JA1
David, R1
Bralley, JA1
Zea-Díaz, H1
Muñoz-Atahualpa, E1
Corrales-Medina, F1
Cuba-Bustinza, C1
Chirinos-Pacheco, J1
Medina-Lezama, J1
Sen, N1
Poyraz, F1
Tavil, Y1
Yazici, HU1
Turfan, M1
Hizal, F1
Topal, S1
Erdamar, H1
Cakir, E1
Yalçin, R1
Cengel, A1
Ayer, JG1
Harmer, JA1
Nakhla, S1
Xuan, W1
Ng, MK1
Marks, GB1
Celermajer, DS1
Vladimirova-Kitova, L1
Deneva, T1
Marinov, B1
Zinellu, A1
Sotgia, S1
Porcu, P1
Casu, MA1
Bivona, G1
Chessa, R1
Deiana, L1
Carru, C1
Dogru, T2
Genc, H2
Tapan, S2
Ercin, CN2
Ors, F2
Aslan, F2
Kara, M2
Sertoglu, E2
Bagci, S2
Kurt, I2
Sonmez, A2
Sladowska-Kozłowska, J1
Litwin, M1
Niemirska, A1
Płudowski, P1
Wierzbicka, A1
Skorupa, E1
Wawer, ZT1
Janas, R1
Karslioglu, Y1
López-Cancio, E1
Galán, A1
Dorado, L1
Jiménez, M1
Hernández, M1
Millán, M1
Reverté, S1
Suñol, A1
Barallat, J1
Massuet, A1
Alzamora, MT1
Dávalos, A1
Arenillas, JF1
Wang, Y1
Chi, Y1
Nanayakkara, PW1
Teerlink, T1
Stehouwer, CD1
Allajar, D1
Spijkerman, A1
Schalkwijk, C1
ter Wee, PM1
van Guldener, C1
Spoto, B1
Benedetto, FA1
Testa, A1
Tripepi, G1
Mallamaci, F1
Maas, R1
Boeger, RH1
Zoccali, C1
Parlongo, RM1
Pisano, A1
Zhang, WR1
Hou, FF1
Ning, JP1
Yang, XB1
Wu, Q1
Tao, LJ1
Chen, BM1
Li, HY1
Chang, L1
Surdacki, A1
Martens-Lobenhoffer, J1
Wloch, A1
Marewicz, E1
Rakowski, T1
Wieczorek-Surdacka, E1
Dubiel, JS1
Pryjma, J1
Bode-Böger, SM1
Kocak, H1
Gumuslu, S1
Ermis, C1
Mahsereci, E1
Sahin, E1
Gocmen, AY1
Ersoy, F1
Suleymanlar, G1
Yakupoglu, G1
Tuncer, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of an Oxidative-Stress-Reducing Strategy Consisting of Pravastatin, Vitamin E and Homocysteine-Lowering on Carotid Intima-Media Thickness in Patients With Mild-to-Moderate Chronic Kidney Disease[NCT00384618]Phase 4100 participants Interventional2001-05-31Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for n(g),n(g')-dimethyl-l-arginine and Carotid Artery Diseases

ArticleYear
A systematic review of the correlation between serum asymmetric dimethylarginine, carotid atherosclerosis and ischaemic stroke.
    European journal of clinical investigation, 2021, Volume: 51, Issue:8

    Topics: Arginine; Carotid Artery Diseases; Humans; Ischemic Stroke

2021

Trials

3 trials available for n(g),n(g')-dimethyl-l-arginine and Carotid Artery Diseases

ArticleYear
Effect of statin on arginine metabolites in treated HIV-infection.
    Atherosclerosis, 2017, Volume: 266

    Topics: Adult; Anti-HIV Agents; Arginine; Biomarkers; Carotid Artery Diseases; Carotid Intima-Media Thicknes

2017
Effects of dialysis solution on the cardiovascular function in peritoneal dialysis patients.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:1

    Topics: Adult; Aged; Arginine; Biomarkers; Blood Flow Velocity; Blood Pressure; Blood Pressure Monitoring, A

2015
Plasma asymmetric dimethylarginine (ADMA) concentration is independently associated with carotid intima-media thickness and plasma soluble vascular cell adhesion molecule-1 (sVCAM-1) concentration in patients with mild-to-moderate renal failure.
    Kidney international, 2005, Volume: 68, Issue:5

    Topics: Adult; Aged; Antioxidants; Arginine; Biomarkers; C-Reactive Protein; Carotid Artery Diseases; Female

2005

Other Studies

21 other studies available for n(g),n(g')-dimethyl-l-arginine and Carotid Artery Diseases

ArticleYear
ADMA/SDMA in elderly subjects with asymptomatic carotid atherosclerosis: values and site-specific association.
    International journal of molecular sciences, 2014, Apr-15, Volume: 15, Issue:4

    Topics: Aged; Aged, 80 and over; Arginine; C-Reactive Protein; Carotid Arteries; Carotid Artery Diseases; Ca

2014
Asymmetric dimethylarginine is associated with high-sensitivity C-reactive protein and early carotid atherosclerosis in women with previous gestational diabetes mellitus.
    Endocrine, 2015, Volume: 48, Issue:2

    Topics: Adult; Arginine; C-Reactive Protein; Carotid Artery Diseases; Carotid Intima-Media Thickness; Diabet

2015
Asymmetric dimethylarginine is associated with carotid atherosclerosis in patients with essential hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:5

    Topics: Arginine; Atherosclerosis; Biomarkers; Blood Pressure; Carotid Artery Diseases; Carotid Artery, Comm

2015
Early childhood hospitalisation with infection and subclinical atherosclerosis in adulthood: the Cardiovascular Risk in Young Finns Study.
    Atherosclerosis, 2015, Volume: 239, Issue:2

    Topics: Adult; Age of Onset; Arginine; Asymptomatic Diseases; Biomarkers; Brachial Artery; Carotid Arteries;

2015
FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis.
    Atherosclerosis, 2015, Volume: 242, Issue:1

    Topics: Amidohydrolases; Arginine; Carotid Artery Diseases; Cells, Cultured; Chromatography, Liquid; Down-Re

2015
Osteoprotegerin is Associated With Endothelial Function and Predicts Early Carotid Atherosclerosis in Patients With Coronary Artery Disease.
    International heart journal, 2015, Volume: 56, Issue:6

    Topics: Aged; Arginine; Biomarkers; Carotid Artery Diseases; Carotid Intima-Media Thickness; Coronary Angiog

2015
Oncological miR-182-3p, a Novel Smooth Muscle Cell Phenotype Modulator, Evidences From Model Rats and Patients.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:7

    Topics: Animals; Arginine; Carotid Artery Diseases; Carotid Artery Injuries; Cell Differentiation; Cell Move

2016
Endogenous nitric oxide synthase inhibitors, arterial hemodynamics, and subclinical vascular disease: the PREVENCION Study.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:6

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Blood Flow Velocity; Blood Pressure; Carotid Artery D

2008
Carotid intima-media thickness in patients with cardiac syndrome X and its association with high circulating levels of asymmetric dimethylarginine.
    Atherosclerosis, 2009, Volume: 204, Issue:2

    Topics: Adult; Arginine; Carotid Artery Diseases; Carotid Artery, Common; Case-Control Studies; Female; Huma

2009
HDL-cholesterol, blood pressure, and asymmetric dimethylarginine are significantly associated with arterial wall thickness in children.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:6

    Topics: Arginine; Biomarkers; Blood Pressure; Cardiovascular Diseases; Carotid Arteries; Carotid Artery Dise

2009
Predictors of the intima-media thickness of carotid artery in asymptomatic newly detected severe hypercholesterolemic patients.
    Clinical physiology and functional imaging, 2010, Volume: 30, Issue:4

    Topics: Adult; Age Factors; Arginine; Biomarkers; Bulgaria; Carotid Arteries; Carotid Artery Diseases; Case-

2010
Carotid restenosis is associated with plasma ADMA concentrations in carotid endarterectomy patients.
    Clinical chemistry and laboratory medicine, 2011, Volume: 49, Issue:5

    Topics: Aged; Arginine; Carotid Artery Diseases; Cohort Studies; Cysteine; Endarterectomy, Carotid; Female;

2011
Elevated asymmetric dimethylarginine in plasma: an early marker for endothelial dysfunction in non-alcoholic fatty liver disease?
    Diabetes research and clinical practice, 2012, Volume: 96, Issue:1

    Topics: Adult; Arginine; Biomarkers; Carotid Artery Diseases; Carotid Intima-Media Thickness; Fatty Liver; H

2012
Oxidative stress in hypertensive children before and after 1 year of antihypertensive therapy.
    Pediatric nephrology (Berlin, Germany), 2012, Volume: 27, Issue:10

    Topics: Adiposity; Adolescent; Albuminuria; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; A

2012
Plasma fetuin-A is associated with endothelial dysfunction and subclinical atherosclerosis in subjects with nonalcoholic fatty liver disease.
    Clinical endocrinology, 2013, Volume: 78, Issue:5

    Topics: Adiponectin; Adult; alpha-2-HS-Glycoprotein; Arginine; Atherosclerosis; Carotid Artery Diseases; Car

2013
Biological signatures of asymptomatic extra- and intracranial atherosclerosis: the Barcelona-AsIA (Asymptomatic Intracranial Atherosclerosis) study.
    Stroke, 2012, Volume: 43, Issue:10

    Topics: Aged; Arginine; Biomarkers; C-Reactive Protein; Carotid Artery Diseases; Cohort Studies; Cross-Secti

2012
Asymmetric dimethylarginine and carotid atherosclerosis in Type 2 diabetes mellitus.
    Journal of endocrinological investigation, 2012, Volume: 35, Issue:9

    Topics: Adult; Aged; Arginine; Carotid Artery Diseases; Case-Control Studies; Diabetes Complications; Diabet

2012
Atherosclerosis and the Glu298Asp polymorphism of the eNOS gene in white patients with end-stage renal disease.
    American journal of hypertension, 2005, Volume: 18, Issue:12 Pt 1

    Topics: Aged; Arginine; Atherosclerosis; Carotid Arteries; Carotid Artery Diseases; Female; Gene Frequency;

2005
Level of asymmetric dimethylarginine and carotid atherosclerosis in patients with chronic kidney disease.
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2006, Volume: 31, Issue:5

    Topics: Adult; Arginine; Carotid Artery Diseases; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged

2006
Elevated plasma asymmetric dimethyl-L-arginine levels are linked to endothelial progenitor cell depletion and carotid atherosclerosis in rheumatoid arthritis.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:3

    Topics: Adult; Arginine; Arthritis, Rheumatoid; Carotid Arteries; Carotid Artery Diseases; Case-Control Stud

2007
Oxidative stress and asymmetric dimethylarginine is independently associated with carotid intima media thickness in peritoneal dialysis patients.
    American journal of nephrology, 2008, Volume: 28, Issue:1

    Topics: Adult; Arginine; Biomarkers; Carotid Artery Diseases; Carotid Artery, Common; Female; Glycation End

2008