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n(g),n(g')-dimethyl-l-arginine and Bronchial Hyperreactivity

n(g),n(g')-dimethyl-l-arginine has been researched along with Bronchial Hyperreactivity in 3 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.

Research Excerpts

ExcerptRelevanceReference
" Alterations in the L-arginine metabolism resulting in reduced availability of the substrate L-arginine for NO synthases, as well as the presence of NO synthase inhibitors such as asymmetric dimethylarginine, contribute to the reduced NO formation and airway dysfunction in asthma."8.90Arginine metabolism in asthma. ( Grasemann, H; Scott, JA, 2014)
"Altered arginine metabolism, the uncoupling of nitric oxide synthase (NOS) by asymmetric dimethyl-arginine (ADMA), increased oxo-nitrosative stress, and cellular injury were reported in airway epithelial cells in asthma."7.77Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma. ( Agrawal, A; Ahmad, T; Aich, J; Ghosh, B; Mabalirajan, U; Makhija, L; Sharma, A, 2011)
" Alterations in the L-arginine metabolism resulting in reduced availability of the substrate L-arginine for NO synthases, as well as the presence of NO synthase inhibitors such as asymmetric dimethylarginine, contribute to the reduced NO formation and airway dysfunction in asthma."4.90Arginine metabolism in asthma. ( Grasemann, H; Scott, JA, 2014)
"Altered arginine metabolism, the uncoupling of nitric oxide synthase (NOS) by asymmetric dimethyl-arginine (ADMA), increased oxo-nitrosative stress, and cellular injury were reported in airway epithelial cells in asthma."3.77Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma. ( Agrawal, A; Ahmad, T; Aich, J; Ghosh, B; Mabalirajan, U; Makhija, L; Sharma, A, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Scott, JA1
Grasemann, H1
Bjørke-Monsen, AL1
Vollsæter, M1
Ueland, PM1
Markestad, T1
Øymar, K1
Halvorsen, T1
Ahmad, T1
Mabalirajan, U1
Sharma, A1
Aich, J1
Makhija, L1
Ghosh, B1
Agrawal, A1

Reviews

1 review available for n(g),n(g')-dimethyl-l-arginine and Bronchial Hyperreactivity

ArticleYear
Arginine metabolism in asthma.
    Immunology and allergy clinics of North America, 2014, Volume: 34, Issue:4

    Topics: Animals; Anti-Asthmatic Agents; Arginine; Asthma; Bronchial Hyperreactivity; Humans; Molecular Targe

2014

Other Studies

2 other studies available for n(g),n(g')-dimethyl-l-arginine and Bronchial Hyperreactivity

ArticleYear
Increased Bronchial Hyperresponsiveness and Higher Asymmetric Dimethylarginine Levels after Fetal Growth Restriction.
    American journal of respiratory cell and molecular biology, 2017, Volume: 56, Issue:1

    Topics: Anthropometry; Arginine; Biomarkers; Bronchial Hyperreactivity; Child; Demography; Female; Fetal Gro

2017
Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma.
    American journal of respiratory cell and molecular biology, 2011, Volume: 44, Issue:4

    Topics: Airway Remodeling; Animals; Arginine; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Flui

2011