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n(g),n(g')-dimethyl-l-arginine and Brain Ischemia

n(g),n(g')-dimethyl-l-arginine has been researched along with Brain Ischemia in 12 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Increased levels of asymmetric dimethylarginine (ADMA) have been observed in patients with acute ischemic stroke."9.19Supplementation of folic acid and vitamin B₁₂ reduces plasma levels of asymmetric dimethylarginine in patients with acute ischemic stroke. ( Li, X; Ma, JP; Wang, JZ; Wang, L; Wu, CJ; Xia, XS, 2014)
"The aim of this study was to evaluate serum ADMA levels, which are an indicator of endothelial dysfunction of the renal functions in patients with acute ischemic stroke, and to determine whether there is a possible correlation between ADMA and NO levels and the l-arginine-to-ADMA ratio."7.91Serum asymmetric dimethylarginine and nitric oxide levels in Turkish patients with acute ischemic stroke. ( Abusoglu, S; Akbulut, D; Bal, C; Celik, HT; Ercan, M; Güzel, I; Mungan, S; Oguz, EF; Yilmaz, FM, 2019)
"To determine the role of asymmetric dimethylarginine (ADMA) in acute lung injury induced by cerebral ischemia/reperfusion (I/R) injury in rats."7.77Role of asymmetric dimethylarginine in acute lung injury induced by cerebral ischemia/reperfusion injury in rats. ( Wang, DH; Wu, YH; Zhang, X, 2011)
"We hypothesise that asymmetric and symmetric dimethylarginine (ADMA, SDMA) are released in cerebrospinal fluid (CSF) due to ischemia-induced proteolysis and that CSF dimethylarginines are related to stroke severity."7.75Dimethylarginine levels in cerebrospinal fluid of hyperacute ischemic stroke patients are associated with stroke severity. ( Brouns, R; De Deyn, PP; Marescau, B; Possemiers, I; Sheorajpanday, R, 2009)
"Delayed cerebral ischemia (DCI) is the major cause of lethality and neuronal damage in patients who survived the primary subarachnoid hemorrhage (SAH)."5.48Asymmetric and Symmetric Dimethylarginines are Markers of Delayed Cerebral Ischemia and Neurological Outcome in Patients with Subarachnoid Hemorrhage. ( Appel, D; Böger, RH; Czorlich, P; Goetz, AE; Hannemann, J; Schwedhelm, E; Seeberger, M, 2018)
"Increased levels of asymmetric dimethylarginine (ADMA) have been observed in patients with acute ischemic stroke."5.19Supplementation of folic acid and vitamin B₁₂ reduces plasma levels of asymmetric dimethylarginine in patients with acute ischemic stroke. ( Li, X; Ma, JP; Wang, JZ; Wang, L; Wu, CJ; Xia, XS, 2014)
"The aim of this study was to evaluate serum ADMA levels, which are an indicator of endothelial dysfunction of the renal functions in patients with acute ischemic stroke, and to determine whether there is a possible correlation between ADMA and NO levels and the l-arginine-to-ADMA ratio."3.91Serum asymmetric dimethylarginine and nitric oxide levels in Turkish patients with acute ischemic stroke. ( Abusoglu, S; Akbulut, D; Bal, C; Celik, HT; Ercan, M; Güzel, I; Mungan, S; Oguz, EF; Yilmaz, FM, 2019)
"Guanidino compounds, including l-homoarginine (l-hArg), symmetric dimethylarginine (SDMA), asymmetric dimethylarginine (ADMA) and l-arginine (l-Arg) are associated with mortality, fatal strokes, stroke incidence, and atherosclerosis."3.91Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHA ( Atzler, D; Böger, RH; Choe, CU; Cordts, K; Gerloff, C; Grant, PJ; Grzybowski, R; Hornig, S; Lezius, S; Lüneburg, N; Magnus, T; Neu, A; Schwedhelm, E; Thomalla, G, 2019)
"To determine the role of asymmetric dimethylarginine (ADMA) in acute lung injury induced by cerebral ischemia/reperfusion (I/R) injury in rats."3.77Role of asymmetric dimethylarginine in acute lung injury induced by cerebral ischemia/reperfusion injury in rats. ( Wang, DH; Wu, YH; Zhang, X, 2011)
"We hypothesise that asymmetric and symmetric dimethylarginine (ADMA, SDMA) are released in cerebrospinal fluid (CSF) due to ischemia-induced proteolysis and that CSF dimethylarginines are related to stroke severity."3.75Dimethylarginine levels in cerebrospinal fluid of hyperacute ischemic stroke patients are associated with stroke severity. ( Brouns, R; De Deyn, PP; Marescau, B; Possemiers, I; Sheorajpanday, R, 2009)
"Delayed cerebral ischemia (DCI) is the major cause of lethality and neuronal damage in patients who survived the primary subarachnoid hemorrhage (SAH)."1.48Asymmetric and Symmetric Dimethylarginines are Markers of Delayed Cerebral Ischemia and Neurological Outcome in Patients with Subarachnoid Hemorrhage. ( Appel, D; Böger, RH; Czorlich, P; Goetz, AE; Hannemann, J; Schwedhelm, E; Seeberger, M, 2018)
"After aneurysmal subarachnoid hemorrhage (SAH) disturbance of this equilibrium may evoke delayed cerebral vasospasm (CVS) leading to delayed cerebral ischemia (DCI)."1.38The CSF concentration of ADMA, but not of ET-1, is correlated with the occurrence and severity of cerebral vasospasm after subarachnoid hemorrhage. ( Jung, CS; Lange, B; Seifert, V; Zimmermann, M, 2012)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's11 (91.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Appel, D1
Seeberger, M1
Schwedhelm, E3
Czorlich, P1
Goetz, AE1
Böger, RH3
Hannemann, J1
Ercan, M1
Mungan, S1
Güzel, I1
Celik, HT1
Bal, C1
Abusoglu, S1
Akbulut, D1
Oguz, EF1
Yilmaz, FM1
Cordts, K1
Grzybowski, R1
Lezius, S1
Lüneburg, N2
Atzler, D1
Neu, A1
Hornig, S1
Gerloff, C1
Magnus, T1
Thomalla, G1
Grant, PJ1
Choe, CU1
Chen, S1
Li, N1
Deb-Chatterji, M1
Dong, Q1
Kielstein, JT1
Weissenborn, K1
Worthmann, H1
Xia, XS1
Li, X1
Wang, L1
Wang, JZ1
Ma, JP1
Wu, CJ1
Brouns, R1
Marescau, B1
Possemiers, I1
Sheorajpanday, R1
De Deyn, PP1
Nishiyama, Y2
Ueda, M2
Katsura, K2
Otsuka, T2
Abe, A2
Nagayama, H2
Katayama, Y2
Mamatha, SN1
Nagaraja, D1
Philip, M1
Christopher, R1
von Holten, RA1
Töpper, RF1
Maas, R1
Wu, YH1
Zhang, X1
Wang, DH1
Jung, CS1
Lange, B1
Zimmermann, M1
Seifert, V1

Reviews

1 review available for n(g),n(g')-dimethyl-l-arginine and Brain Ischemia

ArticleYear
Asymmetric dimethyarginine as marker and mediator in ischemic stroke.
    International journal of molecular sciences, 2012, Nov-28, Volume: 13, Issue:12

    Topics: Animals; Arginine; Biomarkers; Brain Ischemia; Cerebrovascular Circulation; Enzyme Inhibitors; Human

2012

Trials

2 trials available for n(g),n(g')-dimethyl-l-arginine and Brain Ischemia

ArticleYear
Supplementation of folic acid and vitamin B₁₂ reduces plasma levels of asymmetric dimethylarginine in patients with acute ischemic stroke.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:9

    Topics: Aged; Arginine; Blood Chemical Analysis; Brain Ischemia; Dietary Supplements; Female; Folic Acid; Fo

2014
Statin treatment decreased serum asymmetric dimethylarginine (ADMA) levels in ischemic stroke patients.
    Journal of atherosclerosis and thrombosis, 2011, Volume: 18, Issue:2

    Topics: Aged; Aged, 80 and over; Arginine; Atherosclerosis; Atorvastatin; Brain Ischemia; Cholesterol, LDL;

2011

Other Studies

9 other studies available for n(g),n(g')-dimethyl-l-arginine and Brain Ischemia

ArticleYear
Asymmetric and Symmetric Dimethylarginines are Markers of Delayed Cerebral Ischemia and Neurological Outcome in Patients with Subarachnoid Hemorrhage.
    Neurocritical care, 2018, Volume: 29, Issue:1

    Topics: Adult; Aged; Arginine; Biomarkers; Brain Ischemia; Cerebral Angiography; Female; Humans; Incidence;

2018
Serum asymmetric dimethylarginine and nitric oxide levels in Turkish patients with acute ischemic stroke.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2019, Volume: 28, Issue:5

    Topics: Aged; Aged, 80 and over; Arginine; Brain Ischemia; Female; Humans; Male; Middle Aged; Nitric Oxide;

2019
Guanidino compound ratios are associated with stroke etiology, internal carotid artery stenosis and CHA
    Journal of the neurological sciences, 2019, 02-15, Volume: 397

    Topics: Aged; Arginine; Biomarkers; Brain Ischemia; Carotid Arteries; Carotid Stenosis; Cross-Sectional Stud

2019
Dimethylarginine levels in cerebrospinal fluid of hyperacute ischemic stroke patients are associated with stroke severity.
    Neurochemical research, 2009, Volume: 34, Issue:9

    Topics: Aged; Arginine; Brain Ischemia; Female; Humans; Ischemic Attack, Transient; Male; Middle Aged; Strok

2009
Asymmetric dimethylarginine (ADMA) as a possible risk marker for ischemic stroke.
    Journal of the neurological sciences, 2010, Mar-15, Volume: 290, Issue:1-2

    Topics: Age Factors; Aged; Arginine; Biomarkers; Blood Glucose; Brain Ischemia; Cholesterol, LDL; Dyslipidem

2010
Asymmetric dimethylarginine as a risk marker for early-onset ischemic stroke in Indian population.
    Clinica chimica acta; international journal of clinical chemistry, 2011, Jan-14, Volume: 412, Issue:1-2

    Topics: Adolescent; Adult; Analysis of Variance; Arginine; Biomarkers; Brain Ischemia; Case-Control Studies;

2011
Symmetric dimethylarginine is a marker of detrimental outcome in the acute phase after ischaemic stroke: role of renal function.
    Clinical science (London, England : 1979), 2012, Volume: 122, Issue:3

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Brain Ischemia; Chromatography, Liquid; Female; Follo

2012
Role of asymmetric dimethylarginine in acute lung injury induced by cerebral ischemia/reperfusion injury in rats.
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2011, Volume: 31, Issue:8

    Topics: Acute Lung Injury; Animals; Arginine; Brain Ischemia; Male; Myosin-Light-Chain Kinase; Nitric Oxide

2011
The CSF concentration of ADMA, but not of ET-1, is correlated with the occurrence and severity of cerebral vasospasm after subarachnoid hemorrhage.
    Neuroscience letters, 2012, Aug-22, Volume: 524, Issue:1

    Topics: Adult; Arginine; Brain Ischemia; Endothelin-1; Female; Humans; Male; Middle Aged; Nitric Oxide; Retr

2012