n(g),n(g')-dimethyl-l-arginine has been researched along with Body Weight in 21 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, is involved in hypertension." | 7.81 | Aliskiren in early postnatal life prevents hypertension and reduces asymmetric dimethylarginine in offspring exposed to maternal caloric restriction. ( Hsu, CN; Huang, LT; Lee, CT; Tain, YL, 2015) |
| "Elevated asymmetric dimethylarginine (ADMA) levels and nitric oxide (NO) deficiency are associated with the development of hypertension." | 7.80 | Metformin reduces asymmetric dimethylarginine and prevents hypertension in spontaneously hypertensive rats. ( Hsu, CN; Huang, LT; Kuo, HC; Tain, YL; Tsai, CM, 2014) |
| " The present experiments were designed to investigate the role of asymmetrical NG,NG-dimethyl-L-arginine (ADMA) in causing hypertension associated with the focal and segmental glomerulosclerosis (FSGS) produced by a single bolus of puromycin aminonucleoside (PAN) and successive injection of protamine for 7 days in rats which had undergone unilateral nephrectomy." | 7.70 | Endogenous asymmetrical dimethylarginine and hypertension associated with puromycin nephrosis in the rat. ( Azuma, H; Hamasaki, H; Ishizaka, K; Masuda, H; Matsubara, O; Sato, J; Tamaoki, S, 1998) |
| " We examined whether endogenous inhibitors of NO synthesis are involved in the augmentation of intimal hyperplasia in rabbits with hyperglycaemia induced by alloxan." | 7.70 | Accelerated intimal hyperplasia and increased endogenous inhibitors for NO synthesis in rabbits with alloxan-induced hyperglycaemia. ( Azuma, H; Goto, M; Masuda, H; Tamaoki, S, 1999) |
| " The present experiments were designed to investigate the effect of long-term oral nicotine (10 mg/200 ml/kg/day for 7 weeks) on the intimal hyperplasia after endothelial removal of the rabbit carotid artery." | 7.69 | Effect of nicotine on the intimal hyperplasia after endothelial removal of the rabbit carotid artery. ( Azuma, H; Hamasaki, H; Isotani, E; Masuda, H; Obayashi, S; Sato, J; Tamaoki, S; Udagawa, T, 1997) |
| "Asymmetric dimethylarginine (ADMA) is an endogenous modulator of endothelial function and oxidative stress, and increased levels of this molecule have been reported in some metabolic disorders and cardiovascular diseases." | 5.37 | Time course of asymmetric dimethylarginine (ADMA) and oxidative stress in fructose-hypertensive rats: a model related to metabolic syndrome. ( Collin, B; Cottin, Y; Duvillard, L; Goirand, F; Guilland, JC; Korandji, C; Lauzier, B; Moreau, D; Rochette, L; Sicard, P; Vergely, C; Zeller, M, 2011) |
| "Melatonin-treated rats received 0." | 5.36 | Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats. ( Huang, LT; Lau, YT; Lin, CY; Lin, IC; Tain, YL, 2010) |
| "A prospective 12-week pilot study of carvedilol titrated to 50 mg twice daily was performed among 25 hemodialysis participants with intradialytic hypertension." | 5.16 | Probing the mechanisms of intradialytic hypertension: a pilot study targeting endothelial cell dysfunction. ( Inrig, JK; Kim, C; Povsic, TJ; Toto, R; Van Buren, P; Vongpatanasin, W, 2012) |
| "Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, is involved in hypertension." | 3.81 | Aliskiren in early postnatal life prevents hypertension and reduces asymmetric dimethylarginine in offspring exposed to maternal caloric restriction. ( Hsu, CN; Huang, LT; Lee, CT; Tain, YL, 2015) |
| "Elevated asymmetric dimethylarginine (ADMA) levels and nitric oxide (NO) deficiency are associated with the development of hypertension." | 3.80 | Metformin reduces asymmetric dimethylarginine and prevents hypertension in spontaneously hypertensive rats. ( Hsu, CN; Huang, LT; Kuo, HC; Tain, YL; Tsai, CM, 2014) |
| "Adipokines such as leptin and adiponectin are adipocyte-specific secretory proteins that play important roles in the metabolic regulation of body weight, insulin resistance and cardiovascular complications." | 3.76 | Adipokines, endothelial dysfunction and nutritional status in peritoneal dialysis patients. ( Aleksandrowicz-Wrona, E; Lichodziejewska-Niemierko, M; Małgorzewicz, S; Rutkowski, B; Świetlik, D; Łysiak-Szydłowska, W, 2010) |
| " The present experiments were designed to investigate the role of asymmetrical NG,NG-dimethyl-L-arginine (ADMA) in causing hypertension associated with the focal and segmental glomerulosclerosis (FSGS) produced by a single bolus of puromycin aminonucleoside (PAN) and successive injection of protamine for 7 days in rats which had undergone unilateral nephrectomy." | 3.70 | Endogenous asymmetrical dimethylarginine and hypertension associated with puromycin nephrosis in the rat. ( Azuma, H; Hamasaki, H; Ishizaka, K; Masuda, H; Matsubara, O; Sato, J; Tamaoki, S, 1998) |
| " We examined whether endogenous inhibitors of NO synthesis are involved in the augmentation of intimal hyperplasia in rabbits with hyperglycaemia induced by alloxan." | 3.70 | Accelerated intimal hyperplasia and increased endogenous inhibitors for NO synthesis in rabbits with alloxan-induced hyperglycaemia. ( Azuma, H; Goto, M; Masuda, H; Tamaoki, S, 1999) |
| " We examined the hypothesis that HC may inhibit ischemia-induced angiogenesis by inhibition of EDNO in a rat model of unilateral hindlimb ischemia and that oral L-arginine supplementation, a substrate for NO synthase, may prevent HC-related impairment of angiogenesis." | 3.70 | Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism. ( Duan, J; Ikeda, H; Imaizumi, T; Katoh, A; Kawata, H; Murohara, T; Sasaki, K; Shintani, S; Yamamoto, N, 2000) |
| " The present experiments were designed to investigate the effect of long-term oral nicotine (10 mg/200 ml/kg/day for 7 weeks) on the intimal hyperplasia after endothelial removal of the rabbit carotid artery." | 3.69 | Effect of nicotine on the intimal hyperplasia after endothelial removal of the rabbit carotid artery. ( Azuma, H; Hamasaki, H; Isotani, E; Masuda, H; Obayashi, S; Sato, J; Tamaoki, S; Udagawa, T, 1997) |
| "Postocclusive hyperemia is consistently blunted in children with OSA, and such altered endothelial function is reversible 4 to 6 months after treatment, particularly if a family history of cardiovascular disease is not present." | 2.73 | Obstructive sleep apnea and endothelial function in school-aged nonobese children: effect of adenotonsillectomy. ( Dayyat, E; Gozal, D; Kheirandish-Gozal, L; Sans Capdevila, O; Serpero, LD, 2007) |
| "Asymmetric dimethylarginine (ADMA) is an endogenous modulator of endothelial function and oxidative stress, and increased levels of this molecule have been reported in some metabolic disorders and cardiovascular diseases." | 1.37 | Time course of asymmetric dimethylarginine (ADMA) and oxidative stress in fructose-hypertensive rats: a model related to metabolic syndrome. ( Collin, B; Cottin, Y; Duvillard, L; Goirand, F; Guilland, JC; Korandji, C; Lauzier, B; Moreau, D; Rochette, L; Sicard, P; Vergely, C; Zeller, M, 2011) |
| "Melatonin-treated rats received 0." | 1.36 | Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats. ( Huang, LT; Lau, YT; Lin, CY; Lin, IC; Tain, YL, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 11 (52.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Venkatesh, R | 1 |
| Srinivasan, K | 1 |
| Singh, SA | 1 |
| Hu, LL | 1 |
| Zhang, KQ | 1 |
| Tian, T | 1 |
| Zhang, H | 1 |
| Fu, Q | 1 |
| Helle, F | 1 |
| Skogstrand, T | 1 |
| Schwartz, IF | 1 |
| Schwartz, D | 1 |
| Iversen, BM | 1 |
| Palm, F | 1 |
| Hultström, M | 1 |
| Hsu, CN | 2 |
| Lee, CT | 1 |
| Huang, LT | 3 |
| Tain, YL | 3 |
| Tsai, CM | 1 |
| Kuo, HC | 1 |
| Hou, Y | 1 |
| Hu, S | 1 |
| Jia, S | 1 |
| Nawaratna, G | 1 |
| Che, D | 1 |
| Wang, F | 1 |
| Bazer, FW | 1 |
| Wu, G | 1 |
| Campesi, I | 1 |
| Occhioni, S | 1 |
| Tonolo, G | 1 |
| Cherchi, S | 1 |
| Basili, S | 1 |
| Carru, C | 1 |
| Zinellu, A | 1 |
| Franconi, F | 1 |
| Setola, E | 1 |
| Monti, LD | 1 |
| Lanzi, R | 1 |
| Lucotti, P | 1 |
| Losa, M | 1 |
| Gatti, E | 1 |
| Galluccio, E | 1 |
| Oldani, M | 1 |
| Fermo, I | 1 |
| Giovannelli, M | 1 |
| Bosi, E | 1 |
| Piatti, P | 1 |
| Murphy, EC | 1 |
| Carson, L | 1 |
| Neal, W | 1 |
| Baylis, C | 1 |
| Donley, D | 1 |
| Yeater, R | 1 |
| Małgorzewicz, S | 1 |
| Lichodziejewska-Niemierko, M | 1 |
| Aleksandrowicz-Wrona, E | 1 |
| Świetlik, D | 1 |
| Rutkowski, B | 1 |
| Łysiak-Szydłowska, W | 1 |
| Lin, IC | 1 |
| Lau, YT | 1 |
| Lin, CY | 1 |
| Korandji, C | 1 |
| Zeller, M | 1 |
| Guilland, JC | 1 |
| Collin, B | 1 |
| Lauzier, B | 1 |
| Sicard, P | 1 |
| Duvillard, L | 1 |
| Goirand, F | 1 |
| Moreau, D | 1 |
| Cottin, Y | 1 |
| Rochette, L | 1 |
| Vergely, C | 1 |
| Inrig, JK | 1 |
| Van Buren, P | 1 |
| Kim, C | 1 |
| Vongpatanasin, W | 1 |
| Povsic, TJ | 1 |
| Toto, R | 1 |
| Mittermayer, F | 1 |
| Prusa, AR | 1 |
| Pollak, A | 1 |
| Wolzt, M | 1 |
| Hallund, J | 1 |
| Tetens, I | 1 |
| Bügel, S | 1 |
| Tholstrup, T | 1 |
| Ferrari, M | 1 |
| Teerlink, T | 1 |
| Kjaer, A | 1 |
| Wiinberg, N | 1 |
| Gozal, D | 1 |
| Kheirandish-Gozal, L | 1 |
| Serpero, LD | 1 |
| Sans Capdevila, O | 1 |
| Dayyat, E | 1 |
| Yudkoff, M | 1 |
| Nissim, I | 1 |
| Pereira, G | 1 |
| Segal, S | 1 |
| Hamasaki, H | 2 |
| Sato, J | 2 |
| Masuda, H | 3 |
| Tamaoki, S | 3 |
| Isotani, E | 1 |
| Obayashi, S | 1 |
| Udagawa, T | 1 |
| Azuma, H | 3 |
| Ishizaka, K | 1 |
| Matsubara, O | 1 |
| Goto, M | 1 |
| Duan, J | 1 |
| Murohara, T | 1 |
| Ikeda, H | 1 |
| Katoh, A | 1 |
| Shintani, S | 1 |
| Sasaki, K | 1 |
| Kawata, H | 1 |
| Yamamoto, N | 1 |
| Imaizumi, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Blood Pressure, Endothelial Cell Dysfunction, and Outcomes in Dialysis Patients[NCT00827775] | Phase 4 | 55 participants (Actual) | Interventional | 2009-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"ALDH bright cells reported as percentage of mononuclear cells. These were assayed using flow cytometry~CD34/CD133 endothelial progenitor cells reported as percentage of mononuclear cells. These were assayed using flow cytometry" (NCT00827775)
Timeframe: 12 weeks
| Intervention | % of mononuclear cells (Median) | |
|---|---|---|
| Baseline ALDH bright | Baseline CD34/CD133 endothelial progenitor cells | |
| Control | 0.052 | 0.059 |
"ALDH bright cells reported as percentage of mononuclear cells. These were assayed using flow cytometry~CD34/CD133 endothelial progenitor cells reported as percentage of mononuclear cells. These were assayed using flow cytometry" (NCT00827775)
Timeframe: 12 weeks
| Intervention | % of mononuclear cells (Median) | |||
|---|---|---|---|---|
| Baseline ALDH bright | Follow up ALDH bright | Baseline CD34/CD133 endothelial progenitor cells | Follow up CD34/CD133 | |
| Intervention | 0.034 | 0.027 | 0.033 | 0.029 |
Measured as percent change in brachial artery diameter from baseline to post shear stress for an individual measurement. Follow up measurements were obtained in intervention subjects 12 weeks later (NCT00827775)
Timeframe: 12 weeks
| Intervention | % dilation from baseline (Mean) |
|---|---|
| Baseline FMD | |
| Control | 1.67 |
Measured as percent change in brachial artery diameter from baseline to post shear stress for an individual measurement. Follow up measurements were obtained in intervention subjects 12 weeks later (NCT00827775)
Timeframe: 12 weeks
| Intervention | % dilation from baseline (Mean) | |
|---|---|---|
| Baseline FMD | Follow Up FMD | |
| Intervention | 1.03 | 1.4 |
5 trials available for n(g),n(g')-dimethyl-l-arginine and Body Weight
| Article | Year |
|---|---|
Effects of growth hormone treatment on arginine to asymmetric dimethylarginine ratio and endothelial function in patients with growth hormone deficiency.
Topics: Adiposity; Adolescent; Adult; Arginine; Body Weight; Endothelium, Vascular; Female; Growth Disorders | 2008 |
Effects of an exercise intervention using Dance Dance Revolution on endothelial function and other risk factors in overweight children.
Topics: Arginine; Biomarkers; Blood Glucose; Blood Pressure; Body Height; Body Mass Index; Body Weight; Brac | 2009 |
Probing the mechanisms of intradialytic hypertension: a pilot study targeting endothelial cell dysfunction.
Topics: AC133 Antigen; Adult; Aged; Aldehyde Dehydrogenase; Antigens, CD; Antigens, CD34; Antihypertensive A | 2012 |
Daily consumption for six weeks of a lignan complex isolated from flaxseed does not affect endothelial function in healthy postmenopausal women.
Topics: 4-Butyrolactone; Aged; Arginine; Blood Pressure; Body Weight; Cross-Over Studies; Diet; Double-Blind | 2006 |
Obstructive sleep apnea and endothelial function in school-aged nonobese children: effect of adenotonsillectomy.
Topics: Adenoidectomy; Arginine; Body Weight; CD40 Ligand; Child; Endothelium, Vascular; Female; Humans; Hyp | 2007 |
16 other studies available for n(g),n(g')-dimethyl-l-arginine and Body Weight
| Article | Year |
|---|---|
Effect of arginine:lysine and glycine:methionine intake ratios on dyslipidemia and selected biomarkers implicated in cardiovascular disease: A study with hypercholesterolemic rats.
Topics: Administration, Oral; Amino Acids; Animals; Arginine; Biomarkers; Body Weight; Cardiovascular Diseas | 2017 |
Probucol improves erectile function via Activation of Nrf2 and coordinates the HO-1 / DDAH / PPAR-γ/ eNOS pathways in streptozotocin-induced diabetic rats.
Topics: Amidohydrolases; Animals; Arginine; Blood Glucose; Body Weight; Cyclic GMP; Diabetes Mellitus, Exper | 2018 |
Nitric oxide in afferent arterioles after uninephrectomy depends on extracellular L-arginine.
Topics: Angiotensin II; Animals; Arginine; Arterioles; Blood Pressure; Body Weight; Enzyme Inhibitors; Extra | 2013 |
Aliskiren in early postnatal life prevents hypertension and reduces asymmetric dimethylarginine in offspring exposed to maternal caloric restriction.
Topics: Amides; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Arginine; Blood Pressure; Blotti | 2015 |
Metformin reduces asymmetric dimethylarginine and prevents hypertension in spontaneously hypertensive rats.
Topics: Amidohydrolases; Animals; Arginine; Blood Pressure; Body Weight; Hypertension; Kidney; Lung; Male; M | 2014 |
Whole-body synthesis of L-homoarginine in pigs and rats supplemented with L-arginine.
Topics: Animal Feed; Animals; Arginine; Body Weight; Creatinine; Dietary Supplements; Female; Glycine max; H | 2016 |
Ageing/Menopausal Status in Healthy Women and Ageing in Healthy Men Differently Affect Cardiometabolic Parameters.
Topics: Adult; Aging; Arginine; Blood; Body Weight; Female; Humans; Interleukin-6; Male; Malondialdehyde; Mi | 2016 |
Adipokines, endothelial dysfunction and nutritional status in peritoneal dialysis patients.
Topics: Adiponectin; Adult; Aged; Aldehydes; Arginine; Biomarkers; Body Mass Index; Body Weight; C-Reactive | 2010 |
Melatonin prevents hypertension and increased asymmetric dimethylarginine in young spontaneous hypertensive rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Blotting, Western; Body Weight; Citrulline; | 2010 |
Time course of asymmetric dimethylarginine (ADMA) and oxidative stress in fructose-hypertensive rats: a model related to metabolic syndrome.
Topics: Animals; Aorta; Arginine; Blood Glucose; Blood Pressure; Body Weight; Disease Models, Animal; Dose-R | 2011 |
Umbilical vein plasma concentrations of asymmetrical dimethylarginine are increased in male but not female neonates delivered preterm: a pilot study.
Topics: Arginine; Blood Circulation; Body Weight; Female; Fetal Blood; Humans; Infant, Newborn; Male; Nitric | 2006 |
Urinary excretion of dimethylarginines in premature infants.
Topics: Adolescent; Adult; Aging; Arginine; Body Weight; Child; Child, Preschool; Diet; Gestational Age; Hum | 1984 |
Effect of nicotine on the intimal hyperplasia after endothelial removal of the rabbit carotid artery.
Topics: Animals; Arginine; Body Weight; Carotid Arteries; Endothelin-1; Endothelium, Vascular; Hyperplasia; | 1997 |
Endogenous asymmetrical dimethylarginine and hypertension associated with puromycin nephrosis in the rat.
Topics: Animals; Arginine; Blood Pressure; Body Weight; Cyclic GMP; Endothelium; Glomerulosclerosis, Focal S | 1998 |
Accelerated intimal hyperplasia and increased endogenous inhibitors for NO synthesis in rabbits with alloxan-induced hyperglycaemia.
Topics: Alloxan; Animals; Arginine; Blood Glucose; Body Weight; Carotid Arteries; Cyclic GMP; Endothelium, V | 1999 |
Hypercholesterolemia inhibits angiogenesis in response to hindlimb ischemia: nitric oxide-dependent mechanism.
Topics: Administration, Oral; Animals; Arginine; Body Weight; Cholesterol, Dietary; Collateral Circulation; | 2000 |