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n(g),n(g')-dimethyl-l-arginine and Arterial Obstructive Diseases

n(g),n(g')-dimethyl-l-arginine has been researched along with Arterial Obstructive Diseases in 9 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Research Excerpts

ExcerptRelevanceReference
"We investigated in this double-blind, controlled study whether prolonged intermittent infusion therapy with L-arginine improves the clinical symptoms of patients with intermittent claudication, as compared with the endothelium-independent vasodilator prostaglandin E1, and control patients."9.08Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease. ( Alexander, K; Bode-Böger, SM; Böger, RH; Creutzig, A; Frölich, JC; Thiele, W, 1998)
"Hyperhomocysteinemia is associated with an enhanced risk for cardiovascular disease."7.72Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA. ( Arakawa, N; Bode-Böger, SM; Böger, RH; Hornig, B; Münzel, T; Sydow, K; Tsikas, D, 2004)
"We investigated in this double-blind, controlled study whether prolonged intermittent infusion therapy with L-arginine improves the clinical symptoms of patients with intermittent claudication, as compared with the endothelium-independent vasodilator prostaglandin E1, and control patients."5.08Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease. ( Alexander, K; Bode-Böger, SM; Böger, RH; Creutzig, A; Frölich, JC; Thiele, W, 1998)
"Hyperhomocysteinemia is associated with an enhanced risk for cardiovascular disease."3.72Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA. ( Arakawa, N; Bode-Böger, SM; Böger, RH; Hornig, B; Münzel, T; Sydow, K; Tsikas, D, 2004)
" Mechanisms responsible for endothelial dysfunction in hyperhomocyst(e)inemia may involve impaired bioavailability of NO, possibly secondary to accumulation of the endogenous NO synthase inhibitor asymmetric dimethylarginine (ADMA) and increased oxidative stress."2.71ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins. ( Arakawa, N; Bode-Böger, SM; Böger, RH; Frölich, JC; Hornig, B; Schwedhelm, E; Sydow, K; Tsikas, D, 2003)
"Patients with type 2 diabetes (T2DM) have higher incidence of macrovascular disease than the general population."1.33Asymmetric dimethylarginine is associated with macrovascular disease and total homocysteine in patients with type 2 diabetes. ( Hofer, M; Krugluger, W; Krzyzanowska, K; Mittermayer, F; Schernthaner, G; Schnack, C; Wolzt, M, 2006)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's6 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oz, O1
Gökçil, Z1
Bek, S1
Cakir, E1
Odabaşi, Z1
Sydow, K2
Schwedhelm, E1
Arakawa, N2
Bode-Böger, SM5
Tsikas, D3
Hornig, B2
Frölich, JC3
Böger, RH5
Münzel, T1
Krzyzanowska, K1
Mittermayer, F1
Krugluger, W1
Schnack, C1
Hofer, M1
Wolzt, M1
Schernthaner, G1
Blardi, P1
de Lalla, A1
Pieragalli, D1
De Franco, V1
Meini, S1
Ceccatelli, L1
Auteri, A1
Lücke, T1
Kanzelmeyer, NK1
Boerkoel, CF1
Clewing, JM1
Vaske, B1
Ehrich, JH1
Das, AM1
Thiele, W2
Junker, W1
Alexander, K2
Creutzig, A1

Reviews

1 review available for n(g),n(g')-dimethyl-l-arginine and Arterial Obstructive Diseases

ArticleYear
[Endothelial dysfunction in peripheral arterial occlusive disease: from basic research to clinical use].
    VASA. Zeitschrift fur Gefasskrankheiten, 1997, Volume: 26, Issue:3

    Topics: Arginine; Arterial Occlusive Diseases; Arteriosclerosis; Endothelium, Vascular; Humans; Nitric Oxide

1997

Trials

3 trials available for n(g),n(g')-dimethyl-l-arginine and Arterial Obstructive Diseases

ArticleYear
ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins.
    Cardiovascular research, 2003, Volume: 57, Issue:1

    Topics: Aged; Analysis of Variance; Arginine; Arterial Occlusive Diseases; Double-Blind Method; Female; Foli

2003
Effect of iloprost on plasma asymmetric dimethylarginine and plasma and platelet serotonin in patients with peripheral arterial occlusive disease.
    Prostaglandins & other lipid mediators, 2006, Volume: 80, Issue:3-4

    Topics: Aged; Aged, 80 and over; Arginine; Arterial Occlusive Diseases; Blood Platelets; Blood Pressure; Dia

2006
Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease.
    Journal of the American College of Cardiology, 1998, Volume: 32, Issue:5

    Topics: Aged; Aged, 80 and over; Alprostadil; Arginine; Arterial Occlusive Diseases; Blood Flow Velocity; Ch

1998

Other Studies

5 other studies available for n(g),n(g')-dimethyl-l-arginine and Arterial Obstructive Diseases

ArticleYear
Is asymmetric dimethylarginine responsible for the vascular events in patients under antiepileptic drug treatment?
    Epilepsy research, 2009, Volume: 87, Issue:1

    Topics: Adult; Anticonvulsants; Arginine; Arterial Occlusive Diseases; Carbamazepine; Drug Monitoring; Epile

2009
Endothelial dysfunction in patients with peripheral arterial disease and chronic hyperhomocysteinemia: potential role of ADMA.
    Vascular medicine (London, England), 2004, Volume: 9, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Arterial Occlusive Diseases; Chronic Disease; Endothelium,

2004
Asymmetric dimethylarginine is associated with macrovascular disease and total homocysteine in patients with type 2 diabetes.
    Atherosclerosis, 2006, Volume: 189, Issue:1

    Topics: Aged; Arginine; Arterial Occlusive Diseases; Biomarkers; Chromatography, High Pressure Liquid; Cross

2006
Vaso-occlusion in Schimke-immuno-osseous dysplasia: is the NO pathway involved?
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2006, Volume: 38, Issue:10

    Topics: Adolescent; Adult; Arginine; Arterial Occlusive Diseases; Atherosclerosis; Child; Child, Preschool;

2006
Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease.
    Circulation, 1997, Apr-15, Volume: 95, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Arterial Occlusive Diseases; Cyclic GMP; Disease Pr

1997