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n(g),n(g')-dimethyl-l-arginine and Angiogenesis, Pathologic

n(g),n(g')-dimethyl-l-arginine has been researched along with Angiogenesis, Pathologic in 9 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Research Excerpts

ExcerptRelevanceReference
"The endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine (ADMA) is increased in patients with coronary artery disease and may regulate function of circulating angiogenic progenitor cells (APCs) by small regulatory RNAs."7.76Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism. ( Bauersachs, J; Ertl, G; Fiedler, J; Fleissner, F; Galuppo, P; Gupta, SK; Jazbutyte, V; Kneitz, S; Mayr, M; Thum, T; Xu, Q; Yin, X, 2010)
"The endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine (ADMA) is increased in patients with coronary artery disease and may regulate function of circulating angiogenic progenitor cells (APCs) by small regulatory RNAs."3.76Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism. ( Bauersachs, J; Ertl, G; Fiedler, J; Fleissner, F; Galuppo, P; Gupta, SK; Jazbutyte, V; Kneitz, S; Mayr, M; Thum, T; Xu, Q; Yin, X, 2010)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's7 (77.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buijs, N1
Oosterink, JE1
Jessup, M1
Schierbeek, H1
Stolz, DB1
Houdijk, AP1
Geller, DA1
van Leeuwen, PA1
Reddy, KRK1
Dasari, C2
Duscharla, D1
Supriya, B2
Ram, NS1
Surekha, MV1
Kumar, JM2
Ummanni, R2
Wieczór, AM1
Wieczór, R1
Kulwas, A1
Rość, D1
Kami Reddy, KR1
Vandavasi, S1
Natani, S1
Jadav, SS1
Sai Ram, N1
Fleissner, F1
Jazbutyte, V1
Fiedler, J1
Gupta, SK1
Yin, X1
Xu, Q1
Galuppo, P1
Kneitz, S1
Mayr, M1
Ertl, G1
Bauersachs, J1
Thum, T1
Schlager, O1
Giurgea, A1
Schuhfried, O1
Seidinger, D1
Hammer, A1
Gröger, M1
Fialka-Moser, V1
Gschwandtner, M1
Koppensteiner, R1
Steiner, S1
Boult, JK1
Walker-Samuel, S1
Jamin, Y1
Leiper, JM1
Whitley, GS1
Robinson, SP1
Singh, JP1
Wipff, J1
Avouac, J1
Borderie, D1
Zerkak, D1
Lemarechal, H1
Kahan, A1
Boileau, C1
Allanore, Y1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in Type 2 Diabetes ( ZQL007)[NCT03883412]Phase 460 participants (Anticipated)Interventional2019-02-28Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for n(g),n(g')-dimethyl-l-arginine and Angiogenesis, Pathologic

ArticleYear
Asymmetric dimethylarginine and angiogenesis: biological significance.
    International angiology : a journal of the International Union of Angiology, 2018, Volume: 37, Issue:6

    Topics: Animals; Arginine; Atherosclerosis; Cardiovascular Diseases; Endothelial Cells; Humans; Neovasculari

2018
Dimethylarginine dimethylaminohydrolase: a new therapeutic target for the modulation of nitric oxide and angiogenesis.
    Current opinion in investigational drugs (London, England : 2000), 2007, Volume: 8, Issue:9

    Topics: Amidohydrolases; Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Animals; Arginine; Endotheli

2007

Trials

1 trial available for n(g),n(g')-dimethyl-l-arginine and Angiogenesis, Pathologic

ArticleYear
Exercise training increases endothelial progenitor cells and decreases asymmetric dimethylarginine in peripheral arterial disease: a randomized controlled trial.
    Atherosclerosis, 2011, Volume: 217, Issue:1

    Topics: Aged; Arginine; Cell Movement; Chemokine CXCL12; Endothelial Cells; Exercise; Female; Flow Cytometry

2011

Other Studies

6 other studies available for n(g),n(g')-dimethyl-l-arginine and Angiogenesis, Pathologic

ArticleYear
A new key player in VEGF-dependent angiogenesis in human hepatocellular carcinoma: dimethylarginine dimethylaminohydrolase 1.
    Angiogenesis, 2017, Volume: 20, Issue:4

    Topics: Aged; Amidohydrolases; Arginine; Carcinoma, Hepatocellular; Cell Hypoxia; Female; Hep G2 Cells; Huma

2017
Dimethylarginine dimethylaminohydrolase-1 (DDAH1) is frequently upregulated in prostate cancer, and its overexpression conveys tumor growth and angiogenesis by metabolizing asymmetric dimethylarginine (ADMA).
    Angiogenesis, 2018, Volume: 21, Issue:1

    Topics: Amidohydrolases; Animals; Arginine; Cell Movement; Cell Proliferation; Fibroblast Growth Factor 2; G

2018
Novel Cellularly Active Inhibitor Regresses DDAH1 Induced Prostate Tumor Growth by Restraining Tumor Angiogenesis through Targeting DDAH1/ADMA/NOS Pathway.
    ACS combinatorial science, 2019, 04-08, Volume: 21, Issue:4

    Topics: Amidohydrolases; Animals; Antineoplastic Agents; Arginine; Cell Line, Tumor; Cell Proliferation; Cel

2019
Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism.
    Circulation research, 2010, Jul-09, Volume: 107, Issue:1

    Topics: Angiogenesis Inhibitors; Arginine; Coronary Artery Disease; Gene Expression Regulation; Humans; Micr

2010
Active site mutant dimethylarginine dimethylaminohydrolase 1 expression confers an intermediate tumour phenotype in C6 gliomas.
    The Journal of pathology, 2011, Volume: 225, Issue:3

    Topics: Amidohydrolases; Animals; Arginine; Catalytic Domain; Female; Glioma; Magnetic Resonance Imaging; Mi

2011
Disturbed angiogenesis in systemic sclerosis: high levels of soluble endoglin.
    Rheumatology (Oxford, England), 2008, Volume: 47, Issue:7

    Topics: Adult; Aged; Antigens, CD; Arginine; Biomarkers; Cross-Sectional Studies; Endoglin; Female; Humans;

2008