n(g),n(g')-dimethyl-l-arginine has been researched along with Anemia, Sickle Cell in 10 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Asymmetric dimethylarginine (ADMA) is associated with pulmonary hypertension (PHT) in sickle cell disease (SCD)." | 3.76 | Plasma asymmetric dimethylarginine concentrations in sickle cell disease are related to the hemolytic phenotype. ( Biemond, BJ; Brandjes, DP; Duits, AJ; Landburg, PP; Muskiet, FA; Schnog, JB; Teerlink, T, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martins, SR | 1 |
| Toledo, SLO | 1 |
| da Silva, AJ | 1 |
| Mendes, FS | 1 |
| de Oliveira, MM | 1 |
| Ferreira, LGR | 1 |
| Dusse, LMS | 1 |
| Carvalho, MDG | 1 |
| Rios, DRA | 1 |
| Alpoim, PN | 1 |
| Pinheiro, MB | 1 |
| Haymann, JP | 1 |
| Hammoudi, N | 1 |
| Stankovic Stojanovic, K | 1 |
| Galacteros, F | 1 |
| Habibi, A | 1 |
| Avellino, V | 1 |
| Bartolucci, P | 1 |
| Benzerara, Y | 1 |
| Arlet, JB | 1 |
| Djebbar, M | 1 |
| Letavernier, E | 1 |
| Grateau, G | 1 |
| Tabibzadeh, N | 1 |
| Girshovich, A | 1 |
| Chaignon, M | 1 |
| Girot, R | 1 |
| Levy, P | 1 |
| Lionnet, F | 1 |
| Benites, BD | 1 |
| Olalla-Saad, ST | 1 |
| El-Shanshory, M | 1 |
| Badraia, I | 1 |
| Donia, A | 1 |
| Abd El-Hameed, F | 1 |
| Mabrouk, M | 1 |
| Landburg, PP | 3 |
| Teerlink, T | 4 |
| van Beers, EJ | 1 |
| Muskiet, FA | 4 |
| Kappers-Klunne, MC | 1 |
| van Esser, JW | 1 |
| Mac Gillavry, MR | 1 |
| Biemond, BJ | 2 |
| Brandjes, DP | 2 |
| Duits, AJ | 4 |
| Schnog, JJ | 2 |
| Kato, GJ | 1 |
| Wang, Z | 1 |
| Machado, RF | 1 |
| Blackwelder, WC | 1 |
| Taylor, JG | 1 |
| Hazen, SL | 1 |
| Schnog, JB | 2 |
| D'Alecy, LG | 1 |
| Billecke, SS | 1 |
| van der Dijs, FP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Determining the Prevalence and Prognosis of Secondary Pulmonary Hypertension in Adult Patients With Sickle Cell Anemia[NCT00011648] | 986 participants (Actual) | Observational | 2008-02-19 | Completed | |||
| Single-center Prospective Evaluation of Sickle Cell Patient Care in the CHU Brugmann Emergency Department[NCT02386657] | 104 participants (Actual) | Observational | 2012-11-30 | Completed | |||
| Effect of RAS Inhibitors on Albuminuria, Hyperfiltration and Endothelial Dysfunction in a Sickle Cell Disease Population.[NCT01195818] | 53 participants (Actual) | Interventional | 2010-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for n(g),n(g')-dimethyl-l-arginine and Anemia, Sickle Cell
| Article | Year |
|---|---|
An update on arginine in sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Arginine; Hemolysis; Humans; Nitric Oxide; Nitric Oxide Synthase Type | 2019 |
1 trial available for n(g),n(g')-dimethyl-l-arginine and Anemia, Sickle Cell
| Article | Year |
|---|---|
Renin-angiotensin system blockade promotes a cardio-renal protection in albuminuric homozygous sickle cell patients.
Topics: Adult; Albuminuria; Anemia, Sickle Cell; Angiotensin-Converting Enzyme Inhibitors; Arginine; Biomark | 2017 |
8 other studies available for n(g),n(g')-dimethyl-l-arginine and Anemia, Sickle Cell
| Article | Year |
|---|---|
Endothelial dysfunction biomarkers in sickle cell disease: is there a role for ADMA and PAI-1?
Topics: Adolescent; Adult; Anemia, Sickle Cell; Arginine; Biomarkers; Child; Cross-Sectional Studies; Endoth | 2022 |
Asymmetric dimethylarginine levels in children with sickle cell disease and its correlation to tricuspid regurgitant jet velocity.
Topics: Adolescent; Anemia, Sickle Cell; Arginine; Blood Transfusion; Case-Control Studies; Child; Cross-Sec | 2013 |
Association of asymmetric dimethylarginine with sickle cell disease-related pulmonary hypertension.
Topics: Adult; Anemia, Sickle Cell; Arginine; Biomarkers; Female; Humans; Hypertension, Pulmonary; Male; Mid | 2008 |
Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death.
Topics: Anemia, Sickle Cell; Arginine; Case-Control Studies; Citrulline; Follow-Up Studies; Hemolysis; Human | 2009 |
Plasma asymmetric dimethylarginine concentrations in sickle cell disease are related to the hemolytic phenotype.
Topics: Adult; Albuminuria; Anemia, Sickle Cell; Arginine; beta-Thalassemia; Cholelithiasis; Female; Hemolys | 2010 |
Massive quantities of asymmetric dimethylarginine (ADMA) are incorporated in red blood cell proteins and may be released by proteolysis following hemolytic stress.
Topics: Anemia, Sickle Cell; Arginine; Blood Proteins; Erythrocytes; Hemolysis; Humans | 2010 |
Plasma levels of asymmetric dimethylarginine (ADMA), an endogenous nitric oxide synthase inhibitor, are elevated in sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Arginine; Female; Hemoglobin, Sickle; Humans; Male; Middle Aged; Nitric | 2005 |
Plasma concentrations of asymmetric dimethylarginine, an endogenous nitric oxide synthase inhibitor, are elevated in sickle cell patients but do not increase further during painful crisis.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Arginine; Child; Enzyme Inhibitors; Female; Humans; Male; Mi | 2008 |