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n(g),n(g')-dimethyl-l-arginine and Active Hyperemia

n(g),n(g')-dimethyl-l-arginine has been researched along with Active Hyperemia in 13 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Research Excerpts

ExcerptRelevanceReference
"Uric acid is generated with reactive oxygen species via xanthine oxidase (XO), and hyperuricemia, which is identified as the excess of uric acid in the blood, has been associated with vascular endothelial dysfunction."9.34Randomized, Open-Label, Cross-Over Comparison of the Effects of Benzbromarone and Febuxostat on Endothelial Function in Patients with Hyperuricemia. ( Doi, Y; Fukae, S; Ikeda, S; Kawano, H; Koga, S; Maemura, K; Minami, T; Nakata, T; Tsuneto, A; Yonekura, T, 2020)
" We sought to investigate whether ranolazine, a novel antianginal medication with no effect on heart rate or blood pressure, improves endothelial function in patients with stable coronary artery disease (CAD)."9.14Ranolazine improves endothelial function in patients with stable coronary artery disease. ( Coppola, JT; Deshmukh, SH; Hermance, EV; Infantino, MN; Mindrescu, C; Patel, SR; Pinassi, E; Staniloae, CS, 2009)
"The goal of this study was to examine the relationship between plasma asymmetric dimethylarginine (ADMA) level and hyperemic myocardial blood flow (MBF) in subjects with borderline hypertension (BHT) and familial hypercholesterolemia (FH)."7.71Plasma asymmetric dimethylarginine and hyperemic myocardial blood flow in young subjects with borderline hypertension or familial hypercholesterolemia. ( Knuuti, J; Laakso, J; Laaksonen, R; Laine, H; Päivä, H; Raitakari, OT, 2002)
"Uric acid is generated with reactive oxygen species via xanthine oxidase (XO), and hyperuricemia, which is identified as the excess of uric acid in the blood, has been associated with vascular endothelial dysfunction."5.34Randomized, Open-Label, Cross-Over Comparison of the Effects of Benzbromarone and Febuxostat on Endothelial Function in Patients with Hyperuricemia. ( Doi, Y; Fukae, S; Ikeda, S; Kawano, H; Koga, S; Maemura, K; Minami, T; Nakata, T; Tsuneto, A; Yonekura, T, 2020)
" We sought to investigate whether ranolazine, a novel antianginal medication with no effect on heart rate or blood pressure, improves endothelial function in patients with stable coronary artery disease (CAD)."5.14Ranolazine improves endothelial function in patients with stable coronary artery disease. ( Coppola, JT; Deshmukh, SH; Hermance, EV; Infantino, MN; Mindrescu, C; Patel, SR; Pinassi, E; Staniloae, CS, 2009)
" Myocardial blood flow was measured at rest and during adenosine-induced hyperemia using positron emission tomography and oxygen-15-labeled water at baseline and after treatment."5.10Plasma asymmetric dimethylarginine modifies the effect of pravastatin on myocardial blood flow in young adults. ( Janatuinen, T; Knuuti, J; Laakso, J; Laaksonen, R; Lehtimäki, T; Nuutila, P; Raitakari, OT; Vesalainen, R, 2003)
"The goal of this study was to examine the relationship between plasma asymmetric dimethylarginine (ADMA) level and hyperemic myocardial blood flow (MBF) in subjects with borderline hypertension (BHT) and familial hypercholesterolemia (FH)."3.71Plasma asymmetric dimethylarginine and hyperemic myocardial blood flow in young subjects with borderline hypertension or familial hypercholesterolemia. ( Knuuti, J; Laakso, J; Laaksonen, R; Laine, H; Päivä, H; Raitakari, OT, 2002)
"Postocclusive hyperemia is consistently blunted in children with OSA, and such altered endothelial function is reversible 4 to 6 months after treatment, particularly if a family history of cardiovascular disease is not present."2.73Obstructive sleep apnea and endothelial function in school-aged nonobese children: effect of adenotonsillectomy. ( Dayyat, E; Gozal, D; Kheirandish-Gozal, L; Sans Capdevila, O; Serpero, LD, 2007)
"A low peak reactive hyperemia and a low PAT hyperemia ratio before the bicycle test was associated with a high percentage increase in peak reactive hyperemia after exercise (r = - 0."1.42Exercise-induced vasodilation in healthy males: A marker of reduced endothelial function. ( Kjekshus, J; Røysland, R; Torbjørn, O; Wethal, T, 2015)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's7 (53.85)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Nakata, T1
Ikeda, S1
Koga, S1
Yonekura, T1
Tsuneto, A1
Doi, Y1
Fukae, S1
Minami, T1
Kawano, H1
Maemura, K1
Rodrigues-Krause, J1
Krause, M1
Rocha, IMGD1
Umpierre, D1
Fayh, APT1
Žižek, B1
Žižek, D1
Bedenčič, K1
Jerin, A1
Poredoš, P1
Bergström, A1
Staalsø, JM1
Romner, B1
Olsen, NV1
Delaney, CL1
Miller, MD1
Allan, RB1
Spark, JI1
Wethal, T1
Røysland, R1
Torbjørn, O1
Kjekshus, J1
Deshmukh, SH1
Patel, SR1
Pinassi, E1
Mindrescu, C1
Hermance, EV1
Infantino, MN1
Coppola, JT1
Staniloae, CS1
Nerla, R1
Di Monaco, A1
Sestito, A1
Lamendola, P1
Di Stasio, E1
Romitelli, F1
Lanza, GA1
Crea, F1
Scherbakov, N1
Sandek, A1
Martens-Lobenhoffer, J1
Kung, T1
Turhan, G1
Liman, T1
Ebinger, M1
von Haehling, S1
Bode-Böger, SM1
Endres, M1
Doehner, W1
Päivä, H1
Laakso, J2
Laine, H1
Laaksonen, R2
Knuuti, J2
Raitakari, OT2
Janatuinen, T1
Vesalainen, R1
Nuutila, P1
Lehtimäki, T1
Gozal, D1
Kheirandish-Gozal, L1
Serpero, LD1
Sans Capdevila, O1
Dayyat, E1
Tomiyama, H1
Yamada, J1
Koji, Y1
Shiina, K1
Yoshida, M1
Yamashina, A1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Measurements of Endothelial Function by Means of Peripheral Arterial Tonometry in Diabetic Foot Ulcer Patients Undergoing Hyperbaric Oxygen Therapy.[NCT02221466]45 participants (Actual)Observational2014-02-28Completed
Influence of Different Types of Exercise Training on Selected Cardiovascular Parameters in Individuals With Peripheral Arterial Disease[NCT02642276]36 participants (Actual)Interventional2015-06-30Completed
Reduction of Symptomatic Ventricular Premature Beats With Ranolazine[NCT01996618]Phase 472 participants (Anticipated)Interventional2014-01-31Recruiting
Does Ranolazine Decrease Biomarkers That Indicate Evidence of Myocardial Damage in Diabetics With Stable Ischemic Heart Disease? A Double-blinded, Randomized, Placebo Controlled Trial[NCT02611596]0 participants (Actual)Interventional2016-11-30Withdrawn
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for n(g),n(g')-dimethyl-l-arginine and Active Hyperemia

ArticleYear
Association of l-Arginine Supplementation with Markers of Endothelial Function in Patients with Cardiovascular or Metabolic Disorders: A Systematic Review and Meta-Analysis.
    Nutrients, 2018, Dec-20, Volume: 11, Issue:1

    Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus; Dietary Supplements; Endothelium,

2018

Trials

7 trials available for n(g),n(g')-dimethyl-l-arginine and Active Hyperemia

ArticleYear
Randomized, Open-Label, Cross-Over Comparison of the Effects of Benzbromarone and Febuxostat on Endothelial Function in Patients with Hyperuricemia.
    International heart journal, 2020, Sep-29, Volume: 61, Issue:5

    Topics: Adiponectin; Aged; Arginine; Benzbromarone; Cross-Over Studies; Endothelium, Vascular; Febuxostat; F

2020
The impact of different supervised exercise regimens on endothelial function in patients with intermittent claudication.
    Vascular, 2015, Volume: 23, Issue:6

    Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Endothelium, Vascular; Exercise Test; Exercise Therap

2015
Ranolazine improves endothelial function in patients with stable coronary artery disease.
    Coronary artery disease, 2009, Volume: 20, Issue:5

    Topics: Acetanilides; Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Agents; Coronary Artery

2009
Ranolazine improves endothelial function in patients with stable coronary artery disease.
    Coronary artery disease, 2009, Volume: 20, Issue:5

    Topics: Acetanilides; Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Agents; Coronary Artery

2009
Ranolazine improves endothelial function in patients with stable coronary artery disease.
    Coronary artery disease, 2009, Volume: 20, Issue:5

    Topics: Acetanilides; Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Agents; Coronary Artery

2009
Ranolazine improves endothelial function in patients with stable coronary artery disease.
    Coronary artery disease, 2009, Volume: 20, Issue:5

    Topics: Acetanilides; Aged; Arginine; Biomarkers; C-Reactive Protein; Cardiovascular Agents; Coronary Artery

2009
Transient endothelial dysfunction following flow-mediated dilation assessment.
    Heart and vessels, 2011, Volume: 26, Issue:5

    Topics: Adult; Arginine; Biomarkers; Brachial Artery; Endothelium, Vascular; Female; Humans; Hyperemia; Infu

2011
Plasma asymmetric dimethylarginine modifies the effect of pravastatin on myocardial blood flow in young adults.
    Vascular medicine (London, England), 2003, Volume: 8, Issue:3

    Topics: Adenosine; Adult; Anticholesteremic Agents; Arginine; Blood Flow Velocity; Coronary Circulation; Dou

2003
Obstructive sleep apnea and endothelial function in school-aged nonobese children: effect of adenotonsillectomy.
    Circulation, 2007, Nov-13, Volume: 116, Issue:20

    Topics: Adenoidectomy; Arginine; Body Weight; CD40 Ligand; Child; Endothelium, Vascular; Female; Humans; Hyp

2007
Effect of telmisartan on forearm postischemic hyperemia and serum asymmetric dimethylarginine levels.
    American journal of hypertension, 2007, Volume: 20, Issue:12

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Arginine; Benzimidazoles; Benzoates; Blood Pressure;

2007

Other Studies

5 other studies available for n(g),n(g')-dimethyl-l-arginine and Active Hyperemia

ArticleYear
Effect of metabolic abnormalities on endothelial dysfunction in normotensive offspring of subject with hypertension.
    International angiology : a journal of the International Union of Angiology, 2013, Volume: 32, Issue:4

    Topics: Adiponectin; Adult; Arginine; Biomarkers; Brachial Artery; Case-Control Studies; Disease Progression

2013
Impaired endothelial function after aneurysmal subarachnoid haemorrhage correlates with arginine:asymmetric dimethylarginine ratio.
    British journal of anaesthesia, 2014, Volume: 112, Issue:2

    Topics: Adult; Arginine; Biomarkers; Blood Flow Velocity; Endothelium; Female; Follow-Up Studies; Humans; Hy

2014
Exercise-induced vasodilation in healthy males: A marker of reduced endothelial function.
    Scandinavian cardiovascular journal : SCJ, 2015, Volume: 49, Issue:3

    Topics: Adult; Aged; Arginine; Biomarkers; Endothelium, Vascular; Exercise; Exercise Test; Humans; Hyperemia

2015
Endothelial dysfunction of the peripheral vascular bed in the acute phase after ischemic stroke.
    Cerebrovascular diseases (Basel, Switzerland), 2012, Volume: 33, Issue:1

    Topics: Aged; Analysis of Variance; Arginine; Biomarkers; Blood Pressure; Case-Control Studies; Endothelium,

2012
Plasma asymmetric dimethylarginine and hyperemic myocardial blood flow in young subjects with borderline hypertension or familial hypercholesterolemia.
    Journal of the American College of Cardiology, 2002, Oct-02, Volume: 40, Issue:7

    Topics: Adult; Age Factors; Arginine; Biomarkers; Blood Flow Velocity; Case-Control Studies; Coronary Circul

2002