Page last updated: 2024-10-17

n(g),n(g')-dimethyl-l-arginine and ADPKD

n(g),n(g')-dimethyl-l-arginine has been researched along with ADPKD in 3 studies

N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine

Research Excerpts

ExcerptRelevanceReference
"ADPKD patients with higher serum uric acid levels had a higher asymmetric dimethylarginine (ADMA) level (1."5.17Serum uric acid levels and endothelial dysfunction in patients with autosomal dominant polycystic kidney disease. ( Axelsson, J; Eroglu, E; Kalay, N; Kocyigit, I; Orscelik, O; Oymak, O; Sipahioglu, MH; Tokgoz, B; Unal, A; Yilmaz, MI, 2013)
"In experimental models of polycystic kidney disease impaired bioavailability of nitric oxide (NO) and elevated mRNA expression of oxidative stress markers at the kidney level was noted."1.39Elevated asymmetric dimethylarginine is associated with oxidant stress aggravation in patients with early stage autosomal dominant polycystic kidney disease. ( Georgianos, PI; Grekas, DM; Kapoulas, S; Makedou, A; Makedou, K; Raptis, V; Sarafidis, PA; Sioulis, A, 2013)
"Patients with autosomal dominant polycystic kidney disease (ADPKD) with normal renal function have endothelial dysfunction and decreased nitric oxide synthase activity in subcutaneous resistance vessels."1.35Asymmetric dimethylarginine and lipid peroxidation products in early autosomal dominant polycystic kidney disease. ( Borresen, ML; Connors, SG; Luo, Z; Strandgaard, S; Wang, D; Wilcox, CS; Yan, Q, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kocyigit, I1
Yilmaz, MI1
Orscelik, O1
Sipahioglu, MH1
Unal, A1
Eroglu, E1
Kalay, N1
Tokgoz, B1
Axelsson, J1
Oymak, O1
Raptis, V1
Georgianos, PI1
Sarafidis, PA1
Sioulis, A1
Makedou, K1
Makedou, A1
Grekas, DM1
Kapoulas, S1
Wang, D1
Strandgaard, S1
Borresen, ML1
Luo, Z1
Connors, SG1
Yan, Q1
Wilcox, CS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Endothelial Dysfunction in Patients With Polycystic Kidney Disease[NCT01589705]150 participants (Actual)Observational2012-01-31Terminated (stopped due to Patients recruitment and analysis were terminated)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for n(g),n(g')-dimethyl-l-arginine and ADPKD

ArticleYear
Serum uric acid levels and endothelial dysfunction in patients with autosomal dominant polycystic kidney disease.
    Nephron. Clinical practice, 2013, Volume: 123, Issue:3-4

    Topics: Adult; Arginine; C-Reactive Protein; Cross-Sectional Studies; Endothelium, Vascular; Glomerular Filt

2013

Other Studies

2 other studies available for n(g),n(g')-dimethyl-l-arginine and ADPKD

ArticleYear
Elevated asymmetric dimethylarginine is associated with oxidant stress aggravation in patients with early stage autosomal dominant polycystic kidney disease.
    Kidney & blood pressure research, 2013, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Aged; Arginine; Dinoprost; Disease Progression; Female; Glomerular Filtration Rat

2013
Asymmetric dimethylarginine and lipid peroxidation products in early autosomal dominant polycystic kidney disease.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2008, Volume: 51, Issue:2

    Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Cross-Sectional Studies; Enzyme Inhibitors; Femal

2008