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n(6)-carboxymethyllysine and Diabetic Retinopathy

n(6)-carboxymethyllysine has been researched along with Diabetic Retinopathy in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (29.41)18.2507
2000's7 (41.18)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khanna, VK; Kruzliak, P; Meyer, CH; Mishra, N; Saxena, S; Shukla, RK; Singh, V1
Gaspar, L; Khanna, V; Kruzliak, P; Mishra, N; Prasad, S; Ruia, S; Saxena, S; Singh, V; Staffa, R1
Grossin, N; Guillausseau, PJ; Massin, P; Meas, T; Wautier, JL; Wautier, MP1
Kim, CS; Kim, J; Kim, JS; Sohn, E1
Aiello, LP; Asztalos, BF; Cavallerano, JD; Doria, A; Keenan, HA; King, GL; Monnier, VM; Schaefer, EJ; Sell, DR; Strauch, CM; Sun, JK1
Bhadhuri, G; Bhattacharya, B; Choudhuri, S; Chowdhury, IH; Dutta, D; Mitra, B; Mondal, LK; Saha, A; Sen, A1
Alderson, NL; Anderson, NL; Baynes, JW; Boyle, C; Canning, P; Chachich, M; Duffy, N; Frizzell, N; Gardiner, TA; Januszewski, AS; Stitt, A; Thorpe, SR1
Biswas, J; Kumar, SK; Miriam, KC; Nagaraj, RH; Ramakrishnan, S; Sulochana, KN; Swamy-Mruthinti, S1
Hirata, K; Kubo, K1
Cleary, P; Dahms, W; Genuth, S; Malone, J; Monnier, VM; Sell, DR; Sivitz, W; Sun, W1
Bailie, KE; Baynes, JW; Dunn, JA; Dyer, DG; Lyons, TJ; McCance, DR; Thorpe, SR1
Horiuchi, S; Ikeda, K; Inomuta, H; Ishibashi, T; Murata, T; Nagai, R1
Aotaki-Keen, A; Handa, JT; Hjelmeland, LM; Lutty, GA; Matsunaga, H; Miyata, T; te Koppele, JM; Verzijl, N1
Bretzel, RG; Brownlee, M; Hammes, HP; Lin, J; Schleicher, E1
Hamada, Y; Horiuchi, S; Hotta, N; Kasuya, Y; Kato, K; Komori, T; Nagai, R; Nakamura, J; Naruse, K1
Endo, M; Higuchi, M; Koike, T; Makita, Z; Matsuda, A; Matsushita, T; Okamoto, T; Takeuchi, M; Tsuchida, K; Yanagisawa, K1
Baynes, JW; Dunn, JA; Dyer, DG; Lyons, TJ; Silvestri, G1

Other Studies

17 other study(ies) available for n(6)-carboxymethyllysine and Diabetic Retinopathy

ArticleYear
Association of serum N(ε)-Carboxy methyl lysine with severity of diabetic retinopathy.
    Journal of diabetes and its complications, 2016, Volume: 30, Issue:3

    Topics: Adult; Aged; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Humans; Lysine; Male; Middle Aged; Severity of Illness Index

2016
Increased levels of N(ε)- Carboxy methyl lysine (N(ε)-CML) are associated with topographic alterations in retinal pigment epithelium: A preliminary study.
    Journal of diabetes and its complications, 2016, Volume: 30, Issue:5

    Topics: Adult; Biomarkers; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Progression; Female; Glycated Hemoglobin; Humans; Lysine; Male; Middle Aged; Prospective Studies; Regression Analysis; Retinal Pigment Epithelium; Severity of Illness Index; Tertiary Care Centers; Up-Regulation; Vitreoretinopathy, Proliferative

2016
Severity of diabetic microvascular complications is associated with a low soluble RAGE level.
    Diabetes & metabolism, 2008, Volume: 34, Issue:4 Pt 1

    Topics: Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic

2008
Elevated Nε-(carboxymethyl)lysine is associated with apoptosis of retinal pericytes in streptozotocin-induced diabetic rats.
    Ophthalmic research, 2011, Volume: 46, Issue:2

    Topics: Animals; Apoptosis; Caspase 3; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Fluorescent Antibody Technique, Indirect; Glycation End Products, Advanced; In Situ Nick-End Labeling; Lysine; NF-kappa B; Pericytes; Rats; Rats, Sprague-Dawley; Retinal Vessels

2011
Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the joslin 50-year medalist study.
    Diabetes care, 2011, Volume: 34, Issue:4

    Topics: Aged; Arginine; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Female; Humans; Lysine; Male; Middle Aged

2011
Role of N-ε- carboxy methyl lysine, advanced glycation end products and reactive oxygen species for the development of nonproliferative and proliferative retinopathy in type 2 diabetes mellitus.
    Molecular vision, 2013, Volume: 19

    Topics: Adult; Aged; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Glycation End Products, Advanced; Humans; Leukocytes, Mononuclear; Lysine; Male; Middle Aged; Reactive Oxygen Species; Sulfhydryl Compounds; Vitreous Body

2013
The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes.
    Diabetes, 2002, Volume: 51, Issue:9

    Topics: Animals; Capillaries; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Extracellular Matrix; Female; Glycation End Products, Advanced; Laminin; Lysine; Pyridoxamine; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels; RNA, Messenger

2002
Immunolocalization and quantification of advanced glycation end products in retinal neovascular membranes and serum: a possible role in ocular neovascularization.
    Current eye research, 2002, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Epiretinal Membrane; Female; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Lysine; Male; Middle Aged; Pyruvaldehyde; Retinal Neovascularization; Retinal Vasculitis

2002
Relationship between blood levels of N-carboxymethyl-lysine and pentosidine and the severity of microangiopathy in type 2 diabetes.
    Endocrine journal, 2004, Volume: 51, Issue:6

    Topics: Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged

2004
Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications p
    Diabetes, 2005, Volume: 54, Issue:11

    Topics: Adult; Biopsy; Collagen; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Disease Progression; Disease Susceptibility; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Prognosis; Skin; Time Factors

2005
Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Collagen; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Humans; Lysine; Maillard Reaction; Male; Microcirculation; Middle Aged; Skin

1993
The relationship between accumulation of advanced glycation end products and expression of vascular endothelial growth factor in human diabetic retinas.
    Diabetologia, 1997, Volume: 40, Issue:7

    Topics: Aged; Aged, 80 and over; Antibodies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Endothelial Growth Factors; Epitopes; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lymphokines; Lysine; Male; Middle Aged; Retina; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1997
Increase in the advanced glycation end product pentosidine in Bruch's membrane with age.
    Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Bruch Membrane; Choroid; Chromatography, High Pressure Liquid; Diabetic Retinopathy; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Infant; Lysine; Middle Aged; Pigment Epithelium of Eye; Retinal Drusen

1999
Diabetic retinopathy risk correlates with intracellular concentrations of the glycoxidation product Nepsilon-(carboxymethyl) lysine independently of glycohaemoglobin concentrations.
    Diabetologia, 1999, Volume: 42, Issue:5

    Topics: Adult; Deoxyglucose; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Leukocyte Common Antigens; Lysine; Male; Middle Aged; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Pyruvaldehyde; Risk Factors; T-Lymphocytes

1999
Epalrestat, an aldose reductase ihibitor, reduces the levels of Nepsilon-(carboxymethyl)lysine protein adducts and their precursors in erythrocytes from diabetic patients.
    Diabetes care, 2000, Volume: 23, Issue:10

    Topics: Aldehyde Reductase; Blood Glucose; Blood Proteins; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retinopathy; Enzyme Inhibitors; Erythrocytes; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Reference Values; Rhodanine; Thiazolidines

2000
Increased levels of vascular endothelial growth factor and advanced glycation end products in aqueous humor of patients with diabetic retinopathy.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2001, Volume: 33, Issue:5

    Topics: Aged; Aqueous Humor; Biomarkers; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Endothelial Growth Factors; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lymphokines; Lysine; Male; Middle Aged; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2001
Role of glycation in modification of lens crystallins in diabetic and nondiabetic senile cataracts.
    Diabetes, 1991, Volume: 40, Issue:8

    Topics: Aged; Arginine; Cataract; Cataract Extraction; Crystallins; Diabetic Retinopathy; Female; Glycosylation; Humans; Lysine; Male

1991