n(6)-carboxymethyllysine has been researched along with Diabetic Nephropathies in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (15.22) | 18.2507 |
| 2000's | 24 (52.17) | 29.6817 |
| 2010's | 13 (28.26) | 24.3611 |
| 2020's | 2 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Balakrishna, S; Dias, CG; Venkataswamy, L | 1 |
| Choi, CW; Chung, YH; Ha, SK; Han, EH; Huh, YH; Hyon, JY; Jeong Ha, S; Jeong, HG; Jung, SK; Kim, HJ; Kim, Y; Lee, H; Lee, J; Min, JY; Park, J; Yun, SH | 1 |
| An, X; He, M; Li, L; Wang, B; Yao, Q; Zhang, J; Zhang, L | 1 |
| Ahmad, B; Chiew, Y; Kadir, KA; Tan, SMQ | 1 |
| Dahl-Jørgensen, K; Fagerland, MW; Hanssen, KF; Jørum, E; Karimé, B; Mellgren, SI; Monnier, VM; Sveen, KA | 1 |
| Amann, K; Bondeva, T; Daniel, C; Franke, S; Liebisch, M; Wolf, G | 1 |
| Poretsky, L; Striker, GE; Vlassara, H; Woodward, M; Yubero-Serrano, EM | 1 |
| Jing, Z; Kuang, L; Liu, N; Yang, J | 1 |
| Sun, H; Sun, Z; Yuan, Y | 1 |
| Beisswenger, PJ; Howell, S; Knowler, WC; Lemley, KV; Mauer, M; Nelson, RG; Saulnier, PJ; Tanamas, SK; Weil, EJ; Wheelock, KM; Yee, B | 1 |
| Grossin, N; Guillausseau, PJ; Massin, P; Meas, T; Wautier, JL; Wautier, MP | 1 |
| Chang, CJ; Liou, SS; Liu, IM; Tzeng, TF | 1 |
| An, XF; Gao, F; Gu, WJ; Huang, S; Liu, JS; Ten, SC; Wang, X; Yu, JY; Zhao, Y | 1 |
| Burrell, LM; Cooper, ME; Coughlan, MT; Forbes, JM; Jerums, G; MacIsaac, RJ; Patel, SK; Penfold, SA; Sourris, KC; Srivastava, PM; Steer, D; Thomas, MC; Webster, DE | 1 |
| Kang, KS; Kim, HY; Park, JH; Yamabe, N; Yokozawa, T | 1 |
| Aiello, LP; Asztalos, BF; Cavallerano, JD; Doria, A; Keenan, HA; King, GL; Monnier, VM; Schaefer, EJ; Sell, DR; Strauch, CM; Sun, JK | 1 |
| Coughlan, MT; Forbes, JM | 1 |
| Brammar, G; Burns, WC; Cao, Z; Cooper, ME; Forbes, JM; MCLennan, SV; Twigg, SM | 1 |
| Abd el Baki, RF; Andrassy, M; Bierhaus, A; Dugi, KA; Haering, HU; Hamann, A; Kasper, M; Kloeting, I; Mentz, S; Merz, W; Morcos, M; Nawroth, PP; Sayed, AA; Schleicher, E; Schmidt, AM; Schwenger, V; Stern, D; Tritschler, H; van der Woude, F; Waldherr, R; Yard, B; Ziegler, R | 1 |
| Koo, JR; Vaziri, ND | 1 |
| Aoyama, I; Enomoto, A; Nakamura, S; Niwa, T; Tachikawa, T; Takayama, F; Tobita, K | 1 |
| Blazícek, P; Dzúrik, R; Gazdíková, K; Heidland, A; Schinzel, R; Sebeková, K; Spustová, V; Syrová, D | 1 |
| Burns, WC; Cooper, ME; Forbes, JM; Founds, HW; Jerums, G; Thallas, V; Thomas, MC | 1 |
| Abe, M; Hisano, S; Horiuchi, S; Iwasaki, H; Nangaku, M; Sakata, N; Uesugi, N | 1 |
| Hirata, K; Kubo, K | 1 |
| Bassal, S; Cooper, ME; Deemer, ER; El-Osta, A; Forbes, JM; Jerums, G; Long, DM; Osicka, TM; Panagiotopoulos, S; Pete, J; Thallas-Bonke, V; Thomas, MC; Thorpe, SR | 1 |
| Baynes, JW; Bleich, M; Busch, AE; Deemer, EK; Dingermann, T; Huber, J; Münch, G; Schäfer, S; Schmid, K; Somoza, V; Wihler, C | 1 |
| Cleary, P; Dahms, W; Genuth, S; Malone, J; Monnier, VM; Sell, DR; Sivitz, W; Sun, W | 1 |
| Cottalasso, D; Furfaro, AL; Marinari, UM; Menini, S; Odetti, P; Patriarca, S; Pesce, C; Pronzato, MA; Traverso, N | 1 |
| Basgen, J; Brem, H; Cai, W; Li, Z; Peppa, M; Uribarri, J; Vlassara, H; Zhang, JG | 1 |
| Brandstädt, A; Busch, M; Franke, S; Gerth, J; Hunsicker, LG; Ott, U; Stein, G; Wolf, G | 1 |
| Aoki, T; Gohda, T; Hagiwara, S; Horikoshi, S; Ito, T; Kaneko, S; Matsumoto, M; Murakoshi, M; Tanimoto, M; Tomino, Y; Yamada, K | 1 |
| Bach, LA; Cooper, ME; Coughlan, MT; Forbes, JM; Fukami, K; Penfold, SA; Sourris, KC; Thallas-Bonke, V; Thorpe, SR; Yap, FY | 1 |
| Kang, KS; Kim, HY; Yamabe, N; Yokozawa, T | 1 |
| Busch, M; Franke, S; Rohde, RD; Stein, G; Wolf, G | 1 |
| Bailie, KE; Baynes, JW; Dunn, JA; Dyer, DG; Lyons, TJ; McCance, DR; Thorpe, SR | 1 |
| Horie, K; Kurokawa, K; Maeda, K; Miyata, S; Miyata, T; Monnier, VM; Sakai, H; Sugiyama, S; van Ypersole de Strihou, C; Witztum, JL | 1 |
| Horiuchi, S; Imanaga, Y; Meng, J; Nagai, R; Sakata, N; Tachikawa, Y; Takebayashi, S | 1 |
| Horie, K; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Sakai, H; Saotome, N; Suzuki, D; Uchida, K; Yagame, M; Yasuda, Y | 1 |
| Aoyama, I; Katsuzaki, T; Miyazaki, T; Niwa, T; Shimokata, K; Takayama, F; Tsukushi, S | 1 |
| Daimon, M; Eguchi, H; Hirata, A; Igarashi, M; Kato, T; Manaka, H; Ohnuma, H; Ono, Y; Saito, T; Yamaguchi, H | 1 |
| Inagi, R; Kurokawa, K; Miyata, T; Sugiyama, S; Suzuki, D | 1 |
| D'Agati, VD; Fu, C; Kislinger, T; Markowitz, GS; Pischetsrieder, M; Schmidt, AM; Stern, D; Taguchi, A; Tanji, N | 1 |
| Horiuchi, S; Imanaga, Y; Meng, J; Nagai, R; Sakata, N; Takebayashi, S | 1 |
| Heidland, A; Kientsch-Engel, R; Mazák, I; Nagy, J; Schinzel, R; Wagner, Z; Wittmann, I | 1 |
| Horiuchi, S; Meng, J; Nagai, R; Saito, T; Sakata, N; Takebayashi, S; Takeya, M; Uesugi, N | 1 |
5 trial(s) available for n(6)-carboxymethyllysine and Diabetic Nephropathies
| Article | Year |
|---|---|
Tocotrienol-Rich Vitamin E from Palm Oil (Tocovid) and Its Effects in Diabetes and Diabetic Nephropathy: A Pilot Phase II Clinical Trial.
Topics: Aged; Albuminuria; Biomarkers; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Kidney; Lysine; Malaysia; Male; Middle Aged; Pilot Projects; Prospective Studies; Time Factors; Tocotrienols; Treatment Outcome | 2018 |
Effects of sevelamer carbonate on advanced glycation end products and antioxidant/pro-oxidant status in patients with diabetic kidney disease.
Topics: Adiponectin; Age Factors; Aged; Albuminuria; Chelating Agents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dinoprost; Estrogen Receptor alpha; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Intention to Treat Analysis; Lysine; Male; Metformin; Middle Aged; NF-E2-Related Factor 2; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Tumor Necrosis Factor, Type I; RNA, Messenger; Sevelamer; Sex Factors; Single-Blind Method; Sirtuin 1; White People | 2015 |
Advanced Glycation End Products Predict Loss of Renal Function and Correlate With Lesions of Diabetic Kidney Disease in American Indians With Type 2 Diabetes.
Topics: Adult; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Imidazoles; Indians, North American; Kidney; Kidney Glomerulus; Losartan; Lysine; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Pyruvaldehyde | 2016 |
Serum levels of the advanced glycation end products Nepsilon-carboxymethyllysine and pentosidine are not influenced by treatment with the angiotensin receptor II type 1 blocker irbesartan in patients with type 2 diabetic nephropathy and hypertension.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arginine; Biphenyl Compounds; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Hypertension; Irbesartan; Linear Models; Lysine; Male; Middle Aged; Statistics, Nonparametric; Tetrazoles | 2008 |
Immunohistochemical evidence for an increased oxidative stress and carbonyl modification of proteins in diabetic glomerular lesions.
Topics: Adult; Biomarkers; Biopsy, Needle; Culture Techniques; Diabetic Nephropathies; Female; Glomerular Mesangium; Glomerulonephritis, IGA; Glycation End Products, Advanced; Humans; Immunohistochemistry; Kidney Function Tests; Lysine; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Protein Denaturation; Reference Values; Sensitivity and Specificity | 1999 |
41 other study(ies) available for n(6)-carboxymethyllysine and Diabetic Nephropathies
| Article | Year |
|---|---|
Diabetic nephropathy patients show hyper-responsiveness to N6-carboxymethyllysine.
Topics: Culture Media, Conditioned; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Lysine; NF-kappa B | 2022 |
Mitochondrial carnitine palmitoyltransferase 2 is involved in N
Topics: Animals; Blood Glucose; Carnitine O-Palmitoyltransferase; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glycated Hemoglobin; Humans; Kidney; Lysine; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Mitochondria | 2020 |
The receptor for advanced glycation endproducts mediates podocyte heparanase expression through NF-κB signaling pathway.
Topics: Animals; Base Sequence; Cattle; Diabetic Nephropathies; Glucuronidase; Glycation End Products, Advanced; HMGB1 Protein; Kidney Cortex; Lysine; Mice, Inbred C57BL; NF-kappa B; Phosphorylation; Podocytes; Promoter Regions, Genetic; Protein Binding; Proteinuria; Receptor for Advanced Glycation End Products; S100 Proteins; Serum Albumin, Bovine; Signal Transduction; Transcription Factor RelA; Up-Regulation | 2018 |
Small- and large-fiber neuropathy after 40 years of type 1 diabetes: associations with glycemic control and advanced protein glycation: the Oslo Study.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Follow-Up Studies; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Nerve Fibers; Pyruvaldehyde; Sensory Thresholds; Young Adult | 2013 |
Activation of the receptor for advanced glycation end products induces nuclear inhibitor of protein phosphatase-1 suppression.
Topics: Animals; Apoptosis; Case-Control Studies; Cell Cycle Checkpoints; Cell Enlargement; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Diabetic Nephropathies; Down-Regulation; Endoribonucleases; Glycation End Products, Advanced; Humans; Intracellular Signaling Peptides and Proteins; Lysine; Mice; Necrosis; NF-kappa B; Phosphoprotein Phosphatases; Podocytes; Receptor for Advanced Glycation End Products; RNA-Binding Proteins; RNA, Messenger; RNA, Small Interfering; Serum Albumin, Bovine | 2014 |
LC-MS/MS for the simultaneous determination of polar endogenous ADMA and CML in plasma and urine from diabetics.
Topics: Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Linear Models; Lysine; Retrospective Studies; Tandem Mass Spectrometry | 2015 |
Update on Mechanisms of Renal Tubule Injury Caused by Advanced Glycation End Products.
Topics: ATP Binding Cassette Transporter 1; Cell Line; Cholesterol; Diabetic Nephropathies; Endoplasmic Reticulum Stress; Epithelial Cells; Foam Cells; Glycation End Products, Advanced; Humans; Kidney Tubules; Lipid Metabolism; Liver X Receptors; Lysine; Receptors, LDL; Sterol Regulatory Element Binding Protein 2 | 2016 |
Severity of diabetic microvascular complications is associated with a low soluble RAGE level.
Topics: Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2008 |
The amelioration of streptozotocin diabetes-induced renal damage by Wu-Ling-San (Hoelen Five Herb Formula), a traditional Chinese prescription.
Topics: Albuminuria; Animals; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drugs, Chinese Herbal; Fibronectins; Glycation End Products, Advanced; Hypoglycemic Agents; Kidney; Lysine; Magnoliopsida; Male; Mitochondria; NF-kappa B; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta1 | 2009 |
Plasma sRAGE is not associated with urinary microalbumin excretion in type 2 diabetic nephropathy at the early stage.
Topics: Age of Onset; Aged; Albuminuria; Blood Glucose; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme-Linked Immunosorbent Assay; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Lipids; Lysine; Male; Middle Aged; Patient Selection; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2010 |
Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy.
Topics: Aged; Antibodies, Neutralizing; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme-Linked Immunosorbent Assay; Female; HMGB1 Protein; Humans; Ligands; Lysine; Male; Middle Aged; Molecular Weight; Protein Kinase C-alpha; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Transcription, Genetic | 2010 |
Effects of heat-processed ginseng and its active component ginsenoside 20(S)-Rg3 on the progression of renal damage and dysfunction in type 2 diabetic Otsuka Long-Evans Tokushima Fatty rats.
Topics: Animals; Antioxidants; Blood Glucose; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Ginsenosides; Glycation End Products, Advanced; Hypoglycemic Agents; Kidney; Kidney Diseases; Lipid Peroxidation; Lipids; Lysine; Male; Nitric Oxide Synthase Type II; Oxidative Stress; Panax; Phytotherapy; Plant Extracts; Proteinuria; Rats; Rats, Inbred OLETF; Thiobarbituric Acid Reactive Substances | 2010 |
Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the joslin 50-year medalist study.
Topics: Aged; Arginine; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Female; Humans; Lysine; Male; Middle Aged | 2011 |
Temporal increases in urinary carboxymethyllysine correlate with albuminuria development in diabetes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Albuminuria; Animals; Biomarkers; Cytosol; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Gene Expression; Glomerular Filtration Rate; Glycation End Products, Advanced; Kidney Cortex; Lysine; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Streptozocin; Time Factors | 2011 |
Renal connective tissue growth factor induction in experimental diabetes is prevented by aminoguanidine.
Topics: Animals; Cells, Cultured; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibronectins; Gene Expression; Glomerular Mesangium; Glycation End Products, Advanced; Guanidines; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Lysine; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serum Albumin, Bovine | 2002 |
Activation of tubular epithelial cells in diabetic nephropathy.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Epithelium; Glycation End Products, Advanced; Humans; Kidney; Kidney Tubules; Lysine; NF-kappa B; Rats; Rats, Brattleboro; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reference Values; Serum Albumin; Transcription, Genetic; Urine | 2002 |
Effects of diabetes, insulin and antioxidants on NO synthase abundance and NO interaction with reactive oxygen species.
Topics: Animals; Antioxidants; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Insulin; Lysine; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tyrosine | 2003 |
An inhibitor of advanced glycation end product formation reduces N epsilon-(carboxymethyl)lysine accumulation in glomeruli of diabetic rats.
Topics: Age Factors; Animals; Antibodies, Monoclonal; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Fluorescent Antibody Technique, Indirect; Glomerular Mesangium; Glycation End Products, Advanced; Kidney; Kidney Glomerulus; Lysine; Rats; Rats, Inbred OLETF; Rats, Inbred Strains; Thiadiazoles; Thiazolidines | 2003 |
Effects of ramipril in nondiabetic nephropathy: improved parameters of oxidatives stress and potential modulation of advanced glycation end products.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Blood Glucose; Blood Pressure; Creatinine; Cystatin C; Cystatins; Diabetic Nephropathies; Female; Glomerulonephritis; Glycation End Products, Advanced; Homocysteine; Humans; Lipofuscin; Lysine; Male; Malondialdehyde; Middle Aged; Nephritis, Interstitial; Oxidative Stress; Polycystic Kidney Diseases; Ramipril; Severity of Illness Index; Statistics as Topic; Treatment Outcome | 2003 |
The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes.
Topics: Albuminuria; Animal Population Groups; Animals; Blood Pressure; Collagen; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Glycation End Products, Advanced; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kidney; Kinetics; Lysine; Models, Biological; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine | 2003 |
Possible mechanism for medial smooth muscle cell injury in diabetic nephropathy: glycoxidation-mediated local complement activation.
Topics: Acrolein; Adult; Aged; Aged, 80 and over; Arteriosclerosis; Complement Activation; Complement Membrane Attack Complex; Diabetic Nephropathies; Female; Glomerulosclerosis, Focal Segmental; Glycation End Products, Advanced; Humans; Hypertension; Kidney; Kidney Glomerulus; Lysine; Male; Middle Aged; Models, Biological; Nephrosclerosis; Oxidation-Reduction; Tunica Media | 2004 |
Relationship between blood levels of N-carboxymethyl-lysine and pentosidine and the severity of microangiopathy in type 2 diabetes.
Topics: Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged | 2004 |
Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy.
Topics: Alternative Splicing; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Arginine; Blotting, Western; Cattle; Cells, Cultured; Collagen; Diabetic Nephropathies; DNA Primers; Endothelium, Vascular; Glycation End Products, Advanced; Humans; Immunohistochemistry; Immunoprecipitation; Kidney Cortex; Lysine; Male; Microscopy, Fluorescence; Molecular Weight; Peptidyl-Dipeptidase A; Ramipril; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Skin; Time Factors; Up-Regulation | 2005 |
Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and vasopeptidase inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Ascorbic Acid; Blood Glucose; Chromatography, High Pressure Liquid; Creatine; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; Glycation End Products, Advanced; Heterocyclic Compounds, 3-Ring; Kidney; Lysine; Male; Oxidation-Reduction; Protease Inhibitors; Ramipril; Rats; Rats, Zucker; Spectrometry, Fluorescence | 2005 |
Glycation and carboxymethyllysine levels in skin collagen predict the risk of future 10-year progression of diabetic retinopathy and nephropathy in the diabetes control and complications trial and epidemiology of diabetes interventions and complications p
Topics: Adult; Biopsy; Collagen; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Diabetic Retinopathy; Disease Progression; Disease Susceptibility; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Prognosis; Skin; Time Factors | 2005 |
HNE-dependent molecular damage in diabetic nephropathy and its possible prevention by N-acetyl-cysteine and oxerutin.
Topics: Acetylcysteine; Aldehydes; Animals; Apoptosis; Cell Division; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycation End Products, Advanced; Hydroxyethylrutoside; Immunohistochemistry; Kidney Glomerulus; Lipid Peroxidation; Lysine; Male; Rats; Rats, Wistar; Taurine | 2005 |
Prevention and reversal of diabetic nephropathy in db/db mice treated with alagebrium (ALT-711).
Topics: Animals; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Lysine; Mice; Mice, Mutant Strains; Thiazoles | 2006 |
The advanced glycation end product N(epsilon)-carboxymethyllysine is not a predictor of cardiovascular events and renal outcomes in patients with type 2 diabetic kidney disease and hypertension.
Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Disease Progression; Female; Glycation End Products, Advanced; Humans; Hypertension; Lysine; Male; Middle Aged; Multivariate Analysis; Oxidative Stress; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Risk Factors | 2006 |
Effect of pyridoxamine (K-163), an inhibitor of advanced glycation end products, on type 2 diabetic nephropathy in KK-A(y)/Ta mice.
Topics: Animals; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Glycation End Products, Advanced; Immunohistochemistry; Laminin; Lysine; Male; Mice; Pyridoxamine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schiff Bases; Transforming Growth Factor beta1; Tyrosine | 2007 |
Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway.
Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glomerular Mesangium; Glycation End Products, Advanced; Lysine; Male; NADPH Oxidases; Protein Kinase C-alpha; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Superoxides | 2008 |
Role of maltol in advanced glycation end products and free radicals: in-vitro and in-vivo studies.
Topics: Animals; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Glycated Serum Albumin; Glycation End Products, Advanced; Guanidines; Lysine; Male; Proteinuria; Pyrones; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin; Streptozocin; Transcription Factor RelA | 2008 |
Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Collagen; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Humans; Lysine; Maillard Reaction; Male; Microcirculation; Middle Aged; Skin | 1993 |
Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.
Topics: Adolescent; Adult; Aged; Animals; Antibodies; Arginine; Collagen; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Kidney Glomerulus; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Mice; Middle Aged; Nephrotic Syndrome; Norleucine; Pyrroles; Rabbits | 1997 |
Increased advanced glycation end products in atherosclerotic lesions of patients with end-stage renal disease.
Topics: Aged; Aorta; Apolipoproteins B; Arteriosclerosis; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Kidney Failure, Chronic; Lysine; Male; Middle Aged | 1999 |
Increased erythrocyte 3-DG and AGEs in diabetic hemodialysis patients: role of the polyol pathway.
Topics: Adult; Aged; Aldehyde Reductase; Arginine; Creatinine; Deoxyglucose; Diabetic Nephropathies; Enzyme-Linked Immunosorbent Assay; Erythrocytes; Female; Glycation End Products, Advanced; Hemoglobins; Humans; Imidazoles; In Vitro Techniques; Lysine; Male; Middle Aged; Polymers; Renal Dialysis; Sorbitol; Uremia | 1999 |
Increased serum levels of pentosidine, but not carboxymethyl lysine, in type 2 diabetes without obvious diabetic nephropathy.
Topics: Albuminuria; Arginine; Biomarkers; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Reference Values | 1999 |
Increased carbonyl modification by lipids and carbohydrates in diabetic nephropathy.
Topics: Animals; Carbohydrate Metabolism; Cells, Cultured; Diabetic Nephropathies; Glycation End Products, Advanced; Humans; Immunohistochemistry; Kidney Glomerulus; Lipid Metabolism; Lipid Peroxidation; Lysine; Malondialdehyde; Oxidation-Reduction; Rats | 1999 |
Expression of advanced glycation end products and their cellular receptor RAGE in diabetic nephropathy and nondiabetic renal disease.
Topics: Adult; Antibodies; Arginine; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Kidney Diseases; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reference Values; RNA, Messenger | 2000 |
Carboxymethyllysine in dermal tissues of diabetic and nondiabetic patients with chronic renal failure: relevance to glycoxidation damage.
Topics: Aged; Animals; Antibodies, Monoclonal; Collagen; Dermis; Diabetic Nephropathies; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Female; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Male; Mice; Mice, Inbred BALB C; Middle Aged | 2001 |
N(epsilon)-(carboxymethyl)lysine levels in patients with type 2 diabetes: role of renal function.
Topics: Adult; Aged; Aged, 80 and over; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Oxidative Stress | 2001 |
Glycoxidation-modified macrophages and lipid peroxidation products are associated with the progression of human diabetic nephropathy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Diabetic Nephropathies; Female; Glycosylation; Humans; Immunohistochemistry; Kidney Glomerulus; Leukocyte Common Antigens; Lipid Peroxidation; Lysine; Macrophages; Male; Middle Aged; Oxidation-Reduction; Phosphatidylcholines; Receptors, Immunologic; Receptors, Scavenger; Scavenger Receptors, Class A; Severity of Illness Index | 2001 |