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n(6)-carboxymethyllysine and Diabetic Angiopathies

n(6)-carboxymethyllysine has been researched along with Diabetic Angiopathies in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (15.00)18.2507
2000's8 (40.00)29.6817
2010's9 (45.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barzilay, JI; Fonseca, V; Goldfine, AB; Jablonski, KA; Monnier, VM; Shoelson, SE; Strauch, C1
Jing, Z; Kuang, L; Liu, X; Ma, L; Wang, J; Yang, J1
Aubert, CE; Bourron, O; Fonfrede, M; Gillery, P; Hartemann, A; Jaisson, S; Michel, PL; Morel, F1
Brismar, K; Kärvestedt, L; Malmstedt, J; Swedenborg, J1
Chambless, LE; Couper, DJ; Duncan, BB; Heiss, G; Hoogeveen, RC; Luft, VC; Pankow, JS; Schmidt, MI1
Frebelius, S; Jörneskog, G; Lengquist, M; Malmstedt, J; Swedenborg, J; Wang, J1
He, J; Jing, Z; Kuang, L; Liu, N; Sun, Z; Wang, Y; Yang, J1
Gupta, D; Hansen, LM; Joseph, G; Taylor, WR; Weiss, D1
Kamata, K; Kobayashi, T; Matsumoto, T; Ozawa, Y1
An, Y; Chen, D; Jiang, Y; Liu, N; Ren, L; Wang, Z; Zhu, Y1
Cai, W; Crandall, J; Dardaine, V; Goldberg, T; Oberstein, R; Peppa, M; Rayfield, EJ; Vlassara, H1
Boulanger, E; Guillausseau, PJ; Huijberts, M; Laloi-Michelin, M; Levy, B; Massin, P; Wautier, JL; Wautier, MP1
Boulanger, E; Guillausseau, PJ; Massin, P; Wautier, JL; Wautier, MP1
Hirata, K; Kubo, K1
Basta, G; Buzzigoli, E; Casolaro, A; Del Turco, S; Ferrannini, E; Gastaldelli, A; Lazzerini, G; Natali, A; Sironi, AM1
Brandstädt, A; Busch, M; Franke, S; Gerth, J; Hunsicker, LG; Ott, U; Stein, G; Wolf, G1
Heine, RJ; Niessen, HW; Schalkwijk, CG; Simsek, S; van Deutekom, AW1
Bailie, KE; Baynes, JW; Dunn, JA; Dyer, DG; Lyons, TJ; McCance, DR; Thorpe, SR1
Asano, T; Futata, T; Horiuchi, S; Ikeda, K; Meng, J; Myint, T; Nagai, R; Sakata, N; Takebayashi, S; Taniguchi, N1
Berg, TJ; Birkeland, KI; Hanssen, KF; Kilhovd, BK; Thorsby, P1

Trials

3 trial(s) available for n(6)-carboxymethyllysine and Diabetic Angiopathies

ArticleYear
The impact of salsalate treatment on serum levels of advanced glycation end products in type 2 diabetes.
    Diabetes care, 2014, Volume: 37, Issue:4

    Topics: Adiponectin; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Pyruvaldehyde; Salicylates

2014
Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Nov-26, Volume: 99, Issue:24

    Topics: Biomarkers; C-Reactive Protein; Cross-Over Studies; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Female; Food Analysis; Food, Formulated; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Inflammation Mediators; Lipid Peroxidation; Lysine; Male; Middle Aged; Pyruvaldehyde; Risk Factors; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2002
Serum levels of advanced glycation end products are increased in patients with type 2 diabetes and coronary heart disease.
    Diabetes care, 1999, Volume: 22, Issue:9

    Topics: Aged; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Epitopes; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Multivariate Analysis; Risk Factors

1999

Other Studies

17 other study(ies) available for n(6)-carboxymethyllysine and Diabetic Angiopathies

ArticleYear
Quantitative determination of ɛ-N-carboxymethyl-L-lysine in human plasma by liquid chromatography-tandem mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 90

    Topics: Biomarkers; Case-Control Studies; Chromatography, Liquid; Diabetes Mellitus; Diabetic Angiopathies; Humans; Limit of Detection; Lysine; Oxidative Stress; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Uremia

2014
Association of peripheral neuropathy with circulating advanced glycation end products, soluble receptor for advanced glycation end products and other risk factors in patients with type 2 diabetes.
    Diabetes/metabolism research and reviews, 2014, Volume: 30, Issue:8

    Topics: Aged; Arterial Occlusive Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Neuropathies; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Paris; Peripheral Nervous System; Prevalence; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors; Severity of Illness Index; Sex Factors; Solubility; Waist Circumference

2014
The receptor for advanced glycation end products and risk of peripheral arterial disease, amputation or death in type 2 diabetes: a population-based cohort study.
    Cardiovascular diabetology, 2015, Jul-28, Volume: 14

    Topics: Aged; Amputation, Surgical; Biomarkers; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Progression; Disease-Free Survival; Female; Humans; Incidence; Kaplan-Meier Estimate; Lysine; Male; Middle Aged; Peripheral Arterial Disease; Proportional Hazards Models; Receptor for Advanced Glycation End Products; Risk Assessment; Risk Factors; S100A12 Protein; Sweden; Time Factors

2015
Carboxymethyl lysine, an advanced glycation end product, and incident diabetes: a case-cohort analysis of the ARIC Study.
    Diabetic medicine : a journal of the British Diabetic Association, 2016, Volume: 33, Issue:10

    Topics: Atherosclerosis; Case-Control Studies; Cohort Studies; Diabetes Mellitus; Diabetic Angiopathies; Female; Glycation End Products, Advanced; Humans; Incidence; Lysine; Male; Middle Aged; Risk Factors

2016
The Receptor for Advanced Glycation End Products (Rage) and Its Ligands in Plasma and Infrainguinal Bypass Vein.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2016, Volume: 51, Issue:4

    Topics: Adult; Aged; Amputation, Surgical; Biomarkers; Diabetic Angiopathies; Disease-Free Survival; Female; Glycation End Products, Advanced; Humans; Kaplan-Meier Estimate; Ligands; Lysine; Male; Middle Aged; Peripheral Arterial Disease; Proportional Hazards Models; Prospective Studies; Receptor for Advanced Glycation End Products; Reoperation; Risk Factors; S100A12 Protein; Time Factors; Treatment Outcome; Up-Regulation; Vascular Grafting; Veins

2016
ADMA: a specific biomarker for pathologic progress in diabetic microvascular complications?
    Biomarkers in medicine, 2016, Volume: 10, Issue:4

    Topics: Adult; Aged; Area Under Curve; Arginine; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Logistic Models; Lysine; Male; Middle Aged; Odds Ratio; Prediabetic State; ROC Curve; Tandem Mass Spectrometry

2016
The receptor for advanced glycation end products impairs collateral formation in both diabetic and non-diabetic mice.
    Laboratory investigation; a journal of technical methods and pathology, 2017, Volume: 97, Issue:1

    Topics: Animals; Blood Glucose; Collateral Circulation; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Glycation End Products, Advanced; Hindlimb; HMGB1 Protein; Immunoblotting; Immunohistochemistry; Ischemia; Lipids; Lysine; Male; Mice, Inbred C57BL; Mice, Knockout; Receptor for Advanced Glycation End Products

2017
Effect of N-epsilon-(carboxymethyl)lysine on coronary vasoconstriction in isolated perfused hearts from control and streptozotocin-induced diabetic rats.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2009, Volume: 45, Issue:2-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium Channels; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Disease Models, Animal; Drug Synergism; Glycation End Products, Advanced; In Vitro Techniques; Lysine; Male; Rats; Rats, Wistar; Stimulation, Chemical; Streptozocin; Superoxides; Vasoconstriction

2009
Advanced glycation end-product Nε-carboxymethyl-Lysine accelerates progression of atherosclerotic calcification in diabetes.
    Atherosclerosis, 2012, Volume: 221, Issue:2

    Topics: Alkaline Phosphatase; Animals; Apolipoproteins E; Apoptosis; Atherosclerosis; Blotting, Western; Bone Morphogenetic Protein 2; Cell Differentiation; Cell Line; Core Binding Factor Alpha 2 Subunit; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diet, High-Fat; Disease Progression; Glucose; Immunohistochemistry; Injections, Intravenous; Lipoproteins, LDL; Lysine; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Osteogenesis; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Staining and Labeling; Time Factors; Vascular Calcification

2012
N(carboxymethyl)lysine as a biomarker for microvascular complications in type 2 diabetic patients.
    Diabetes & metabolism, 2003, Volume: 29, Issue:1

    Topics: Biomarkers; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Microcirculation; Middle Aged

2003
AGEs, macrophage colony stimulating factor and vascular adhesion molecule blood levels are increased in patients with diabetic microangiopathy.
    Thrombosis and haemostasis, 2004, Volume: 91, Issue:5

    Topics: Aged; Biomarkers; Case-Control Studies; Coculture Techniques; Diabetic Angiopathies; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Erythrocytes; Female; Glycation End Products, Advanced; Humans; Lysine; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Umbilical Veins; Up-Regulation; Vascular Cell Adhesion Molecule-1

2004
Relationship between blood levels of N-carboxymethyl-lysine and pentosidine and the severity of microangiopathy in type 2 diabetes.
    Endocrine journal, 2004, Volume: 51, Issue:6

    Topics: Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged

2004
Circulating soluble receptor for advanced glycation end products is inversely associated with glycemic control and S100A12 protein.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:11

    Topics: Adult; Aged; Blood Glucose; Blood Pressure; C-Reactive Protein; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Inflammation Mediators; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors; S100 Proteins; S100A12 Protein; Statistics as Topic

2006
The advanced glycation end product N(epsilon)-carboxymethyllysine is not a predictor of cardiovascular events and renal outcomes in patients with type 2 diabetic kidney disease and hypertension.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 48, Issue:4

    Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Disease Progression; Female; Glycation End Products, Advanced; Humans; Hypertension; Lysine; Male; Middle Aged; Multivariate Analysis; Oxidative Stress; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Risk Factors

2006
Increased Nepsilon-(carboxymethyl)-lysine levels in cerebral blood vessels of diabetic patients and in a (streptozotocin-treated) rat model of diabetes mellitus.
    European journal of endocrinology, 2008, Volume: 158, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Brain; Cerebrovascular Circulation; Child; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Rats; Rats, Wistar

2008
Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Collagen; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Humans; Lysine; Maillard Reaction; Male; Microcirculation; Middle Aged; Skin

1993
Glycoxidation in aortic collagen from STZ-induced diabetic rats and its relevance to vascular damage.
    Atherosclerosis, 1998, Volume: 136, Issue:2

    Topics: Aldehydes; Animals; Aorta; Collagen; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Immunohistochemistry; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Streptozocin

1998