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n(6)-carboxymethyllysine and Diabetes Mellitus

n(6)-carboxymethyllysine has been researched along with Diabetes Mellitus in 58 studies

*Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE. [MeSH]

Research

Studies (58)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.72)	18.7374
1990's	9 (15.52)	18.2507
2000's	24 (41.38)	29.6817
2010's	21 (36.21)	24.3611
2020's	3 (5.17)	2.80

Authors

Authors	Studies
Berendschot, TTJM; de Galan, B; Eussen, SJMP; Henry, RMA; Houben, AJHM; Kroon, AA; Linkens, AMA; Schalkwijk, CG; Schram, MT; Stehouwer, CDA; van Greevenbroek, M; Webers, CAB	1
Li, L; Pang, M; Shao, C; Sun, Z; Wang, Z; Zhang, L	1
Jing, Q; Li, L; Mao, X; Qian, Y; Sun, Z; Wang, Z; Yin, K; Zang, G; Zhang, L	1
Broers, NJH; Canaud, B; Christiaans, MHL; Cornelis, T; Gauly, A; Hermans, MMH; Konings, CJAM; Kooman, JP; Martens, RJH; Schalkwijk, CG; Scheijen, JLJM; Stifft, F; van der Sande, FM; Wirtz, JJJM	1
Cocuzzi, E; Flückiger, R; Kern, TS; Medof, ME; Nagaraj, RH; Shoham, M	1
Feskens, EJM; Hanssen, NMJ; Schalkwijk, CG; Scheijen, JLJM; Stehouwer, CDA; Van der Kallen, CJ; van Greevenbroek, MM	1
Alfonso, H; Almeida, OP; Davis, TME; Flicker, L; Forbes, J; Golledge, J; Hankey, GJ; Irrgang, F; Lamb, LS; Müench, G; Norman, PE; Yeap, BB	1
Moroishi, N; Nagai, M; Nagai, R; Ohno, R; Shirakawa, J	1
Brimble, MA; Cooper, GJ; Woods, TM	1
Han, L; Li, B; Li, L; Li, Y; Liu, G; Xu, Z; Zhao, D	1
He, W; Hu, S; Liu, Z; Ma, G; Xu, H	1
He, W; Hu, S; Liu, Z; Ma, G; Xu, H; Yan, G	1
Jing, Z; Kuang, L; Liu, X; Ma, L; Wang, J; Yang, J	1
Hara, S; Nagashima, H; Nagata, M; Umeyama, K; Yokoo, T	1
Fukami, K; Matsui, T; Yamagishi, S	1
Ferrucci, L; Garcia, M; Harris, TB; Newman, AB; Satterfield, S; Schwartz, AV; Semba, RD; Sun, K; Varadhan, R	1
Balasubramanyam, M; Bhat, S; Giri, AP; Jagadeeshaprasad, MG; Jayaramaiah, RH; Korwar, AM; Kulkarni, MJ; Mohan, V; Ramaswamy, S; Regin, BS; Vannuruswamy, G	1
Chambless, LE; Couper, DJ; Duncan, BB; Heiss, G; Hoogeveen, RC; Luft, VC; Pankow, JS; Schmidt, MI	1
Chang, CR; Chen, MH; Kao, SH; Lee, HM; Lee, WS; Lo, MC; Lu, CI	1
Beck, J; Dalal, M; Ferrucci, L; Fried, LP; Guralnik, JM; Semba, RD; Sun, K; Varadhan, R; Walston, J	1
Fujimoto, S; Miyazaki, A; Yoshikawa, T	1
Coughlan, MT; Davis, TM; Davis, WA; Forbes, JM; Golledge, J; Norman, PE	1
Meerwaldt, R; Zeebregts, CJ	1
Beck, J; Carlson, OD; Egan, JM; Ferrucci, L; Semba, RD; Sun, K; Varadhan, R	1
Amiri, I; Goodarzi, MT; Karimi, J; Khodadadi, I; Tavilani, H	1
Ang, A; Arab, L; Crasto, C; Dalal, M; Ferrucci, L; Jardack, P; Semba, RD; Talegawkar, S; Traber, MG	1
Kellow, NJ; Savige, GS	1
Cai, W; Crandall, J; Dardaine, V; Goldberg, T; Oberstein, R; Peppa, M; Rayfield, EJ; Vlassara, H	1
Busch, M; Franke, C; Franke, S; Müller, A; Niwa, T; Stein, G; Wendt, T	1
Dworacka, M; Szczawińska, K; Szymańska, M; Wierusz-Wysocka, B; Winiarska, H	1
Bach, LA; Cooper, ME; Gallicchio, M; Jerums, G; McRobert, EA	1
Chibber, R; Ferro, A; Kohner, E; Ritter, J; Ruggerio, D; Ruggiero, D; Xu, B	1
Dawczynski, J; Franke, S; Niwa, T; Stahl, P; Stein, G; Strobel, J	1
Baliga, S; Cai, W; Goldberg, T; Lu, M; Peppa, M; Uribarri, J; Vassalotti, JA; Vlassara, H	1
Hudson, BG; Jacob, J; Khalifah, RG; Serianni, AS; Thibaudeau, C; Voziyan, PA; Yildiz, A	1
DeGroot, J; Hughes, TE; Kiers, GH; Quinn, D; TeKoppele, JM; Valencia, JV; Weldon, SC	1
Cruz-Sánchez, CZ; Cruz-Sánchez, FF; Gironès, X; Guimerà, A; Kalaria, R; Lafuente, JV; Makita, Z; Ortega, A; Sasaki, N	1
Baidoshvili, A; Niessen, HW; Schalkwijk, CG; Stehouwer, CD; van Hinsbergh, VW	1
Appel, T; Franke, S; Kientsch-Engel, R; Müller, UA; Ross, IS; Schiel, R; Stein, G; Voigt, U	1
Machado, AP; Moysés, ZP; Nakandakare, ER; Passarelli, M; Pinto, RS; Quintão, EC	1
Anraku, M; Kitamura, K; Maruyama, T; Mera, K; Nakajou, K; Otagiri, M; Tomita, K	1
Hammes, HP; Linder, M; Preissner, KT; Schmitt, S; Ständker, L	1
Agbaje, IM; Atkinson, AB; Glenn, JV; Mallidis, C; McClure, N; Pringle, R; Rogers, DA; Steger, K; Stitt, AW	1
Khaidar, A; Lubec, B; Lubec, G; Marx, M	1
Nerlich, AG; Schleicher, ED; Wagner, E	1
Bailey, AJ; Paul, RG	1
Ahmed, MU; Baynes, JW; Brinkmann, E; Litchfield, JE; Reddy, S; Thorpe, SR; Wells-Knecht, KJ; Wells-Knecht, MC; Zyzak, DV	1
Ahmed, MU; Fu, MX; Jenkins, AJ; Lyons, TJ; Requena, JR; Thorpe, SR	1
Baynes, JW; Lyons, TJ; McCance, DR; Thorpe, SR; Wells-Knecht, MC	1
Monnier, VM; Saxena, AK; Weiss, MF	1
Du Yan, S; Fu, C; Hofmann, M; Huber, B; Kislinger, T; Pischetsrieder, M; Qu, W; Schmidt, AM; Stern, D; Taguchi, A; Yan, SF	1
Baynes, JW; Litchfield, JE; Thorpe, SR	1
Amano, S; Araie, M; Horiuchi, S; Ishibashi, T; Kaji, Y; Matsubara, M; Murata, T; Nagai, R; Oshika, T; Usui, T; Yamashita, H	1
Chellan, P; Duve, Y; Glomb, MA; Jiang, CL; Madhun, Z; Nagaraj, RH; Sady, C	1
Faist, V; Heidland, A; Klvanová, J; Krajcoviová-Kudlácková, M; Schinzel, R; Sebeková, K	1
Lalla, E; Lamster, IB; Schmidt, AM; Stern, DM	1
Makita, Z; Takeuchi, M	1
Ah-Sing, E; Gould, BJ; Stace, BC; Walsh, DP; Wright, J	1

Reviews

9 review(s) available for n(6)-carboxymethyllysine and Diabetes Mellitus

Article	Year
Inhibition of AGEs formation by natural products. Amino acids, 2014, Volume: 46, Issue:2 Topics: Animals; Biological Products; Carbohydrate Metabolism; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lipid Metabolism; Lysine	2014
Review of the characteristics of food-derived and endogenous ne-carboxymethyllysine. Journal of food protection, 2013, Volume: 76, Issue:5 Topics: Consumer Product Safety; Diabetes Mellitus; Food Contamination; Food Handling; Glycation End Products, Advanced; Humans; Lysine	2013
Role of receptor for advanced glycation end products (RAGE) and its ligands in cancer risk. Rejuvenation research, 2015, Volume: 18, Issue:1 Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Diabetes Mellitus; Disease Progression; Humans; Inflammation; Ligands; Lysine; Melanoma; Mice; Neoplasm Metastasis; Neoplasms; Oxidative Stress; Receptor for Advanced Glycation End Products; Risk Factors; Treatment Outcome	2015
Dietary advanced glycation end-product restriction for the attenuation of insulin resistance, oxidative stress and endothelial dysfunction: a systematic review. European journal of clinical nutrition, 2013, Volume: 67, Issue:3 Topics: Diabetes Mellitus; Diet; Endothelium; Glycation End Products, Advanced; Humans; Insulin Resistance; Lysine; Oxidative Stress; Randomized Controlled Trials as Topic; Renal Insufficiency	2013
Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes. The international journal of biochemistry & cell biology, 1996, Volume: 28, Issue:12 Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Elastin; Glycation End Products, Advanced; Glycosylation; Humans; Imidazoles; Lysine; Maillard Reaction; Malondialdehyde; Norleucine; Pyrroles	1996
New biomarkers of Maillard reaction damage to proteins. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11 Suppl 5 Topics: Aging; Arginine; Biomarkers; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Lysine; Maillard Reaction; Molecular Structure; Norleucine; Oxidation-Reduction; Proteins; Pyrroles	1996
Lipoxidation products as biomarkers of oxidative damage to proteins during lipid peroxidation reactions. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11 Suppl 5 Topics: Aldehydes; Arteriosclerosis; Biomarkers; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lipid Peroxidation; Lipoproteins, LDL; Lysine; Maillard Reaction; Malondialdehyde; Oxidative Stress; Proteins	1996
Receptor for advanced glycation end products, inflammation, and accelerated periodontal disease in diabetes: mechanisms and insights into therapeutic modalities. Annals of periodontology, 2001, Volume: 6, Issue:1 Topics: Alveolar Bone Loss; Animals; Diabetes Mellitus; Disease Models, Animal; Endothelium, Vascular; Glycation End Products, Advanced; Hyperglycemia; Immunoglobulins; Ligands; Lysine; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Periodontal Diseases; Periodontitis; Phagocytes; Receptor for Advanced Glycation End Products; Receptors, Immunologic	2001
Alternative routes for the formation of immunochemically distinct advanced glycation end-products in vivo. Current molecular medicine, 2001, Volume: 1, Issue:3 Topics: Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Immunochemistry; Lysine; Models, Biological; Oxidation-Reduction	2001

Trials

5 trial(s) available for n(6)-carboxymethyllysine and Diabetes Mellitus

Article	Year
Relations of advanced glycation endproducts and dicarbonyls with endothelial dysfunction and low-grade inflammation in individuals with end-stage renal disease in the transition to renal replacement therapy: A cross-sectional observational study. PloS one, 2019, Volume: 14, Issue:8 Topics: Adult; Aged; Biomarkers; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus; Endothelium, Vascular; Female; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Ornithine; Renal Dialysis	2019
Decrease in serum levels of advanced glycation end-products by short-term lifestyle modification in non-diabetic middle-aged females. Medical science monitor : international medical journal of experimental and clinical research, 2009, Volume: 15, Issue:6 Topics: Adiposity; Adult; Aged; Arginine; Body Weight; Case-Control Studies; Diabetes Mellitus; Exercise; Female; Glycation End Products, Advanced; Humans; Life Style; Lysine; Middle Aged; Regression Analysis; Time Factors; Walking	2009
Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy. Proceedings of the National Academy of Sciences of the United States of America, 2002, Nov-26, Volume: 99, Issue:24 Topics: Biomarkers; C-Reactive Protein; Cross-Over Studies; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Female; Food Analysis; Food, Formulated; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Inflammation Mediators; Lipid Peroxidation; Lysine; Male; Middle Aged; Pyruvaldehyde; Risk Factors; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	2002
Serum N-epsilon-(carboxymethyl)lysine is elevated in nondiabetic coronary heart disease patients. Journal of basic and clinical physiology and pharmacology, 2002, Volume: 13, Issue:3 Topics: Arteriosclerosis; C-Peptide; Carbohydrate Metabolism; Cholesterol, HDL; Coronary Disease; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Female; Glucose; Humans; Islets of Langerhans; Lipid Metabolism; Lipoproteins, HDL; Lysine; Male; Middle Aged; Oxidation-Reduction	2002
Improvement of the quality of diabetes control and decrease in the concentrations of AGE-products in patients with type 1 and insulin-treated type 2 diabetes mellitus: results from a 10 year-prospective, population-based survey on the quality of diabetes European journal of medical research, 2004, Aug-31, Volume: 9, Issue:8 Topics: Adolescent; Adult; Arginine; Creatinine; Diabetes Complications; Diabetes Mellitus; Female; Germany; Glycation End Products, Advanced; Health Surveys; Humans; Insulin; Longitudinal Studies; Lysine; Male; Middle Aged; Prospective Studies; Time Factors	2004

Other Studies

44 other study(ies) available for n(6)-carboxymethyllysine and Diabetes Mellitus

Article	Year
Habitual intake of dietary advanced glycation end products is not associated with generalized microvascular function-the Maastricht Study. The American journal of clinical nutrition, 2022, 02-09, Volume: 115, Issue:2 Topics: Aged; Biomarkers; Chromatography, Liquid; Cross-Sectional Studies; Diabetes Mellitus; Diet; Female; Glycation End Products, Advanced; Humans; Kidney; Lysine; Male; Mass Spectrometry; Microcirculation; Middle Aged; Nutritional Physiological Phenomena; Ornithine; Prospective Studies; Retinal Vessels; Skin	2022
Nε-Carboxymethyl-Lysine Mediates Vascular Calcification in Diabetes Caused by Impaired Osteoclastic Resorption Activity Through NFATc1-GNPTAB. Journal of cardiovascular translational research, 2023, Volume: 16, Issue:1 Topics: Bone Resorption; Cell Differentiation; Diabetes Mellitus; Humans; NFATC Transcription Factors; Osteoclasts; Plaque, Atherosclerotic; Transcription Factors; Transferases (Other Substituted Phosphate Groups); Vascular Calcification	2023
SIRT3-and FAK-mediated acetylation-phosphorylation crosstalk of NFATc1 regulates N Atherosclerosis, 2023, Volume: 377 Topics: Acetylation; Animals; Cells, Cultured; Diabetes Mellitus; Focal Adhesion Protein-Tyrosine Kinases; Humans; Mice; Myocytes, Smooth Muscle; NFI Transcription Factors; Osteogenesis; Phosphorylation; Sirtuin 3; Vascular Calcification	2023
DAF in diabetic patients is subject to glycation/inactivation at its active site residues. Molecular immunology, 2018, Volume: 93 Topics: Amino Acids; Arginine; Catalytic Domain; CD55 Antigens; Complement Activation; Diabetes Mellitus; Erythrocytes; Glucose; Glycation End Products, Advanced; Humans; Lymphocyte Activation; Lysine; Models, Molecular; Ornithine; Protein Conformation; Pyrimidines; Ribose	2018
Dietary intake of advanced glycation endproducts is associated with higher levels of advanced glycation endproducts in plasma and urine: The CODAM study. Clinical nutrition (Edinburgh, Scotland), 2018, Volume: 37, Issue:3 Topics: Aged; Atherosclerosis; Body Mass Index; Cohort Studies; Diabetes Mellitus; Diet; Female; Food Handling; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Ornithine; Waist Circumference	2018
Advanced Glycation End Products and esRAGE Are Associated With Bone Turnover and Incidence of Hip Fracture in Older Men. The Journal of clinical endocrinology and metabolism, 2018, 11-01, Volume: 103, Issue:11 Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Blood Glucose; Bone Density; Bone Remodeling; Diabetes Mellitus; Follow-Up Studies; Glycation End Products, Advanced; Hip Fractures; Humans; Incidence; Lysine; Male; Predictive Value of Tests; Prognosis; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Risk Factors	2018
Synthesis of stable isotope-labelled monolysyl advanced glycation endproducts. Amino acids, 2013, Volume: 45, Issue:2 Topics: Diabetes Mellitus; Glycation End Products, Advanced; Isotope Labeling; Lysine; Mass Spectrometry; Norleucine; Pyrroles	2013
The accumulation of the glycoxidation product N(ε)-carboxymethyllysine in cardiac tissues with age, diabetes mellitus and coronary heart disease. The Tohoku journal of experimental medicine, 2013, Volume: 230, Issue:1 Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Coronary Artery Disease; Diabetes Mellitus; Female; Glycosylation; Humans; Infant; Lysine; Male; Middle Aged; Myocardium; Oxidation-Reduction; Smoking; Young Adult	2013
The influence of disease and age on human cardiac stem cells. Annals of clinical biochemistry, 2014, Volume: 51, Issue:Pt 5 Topics: Adolescent; Adult; Age Factors; Aged; Cells, Cultured; Child; Child, Preschool; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus; Flow Cytometry; Humans; Infant; Lysine; Middle Aged; Myocardium; Myocytes, Cardiac; Proto-Oncogene Proteins c-kit; Stem Cells; Young Adult	2014
Quantitative determination of ɛ-N-carboxymethyl-L-lysine in human plasma by liquid chromatography-tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis, 2014, Volume: 90 Topics: Biomarkers; Case-Control Studies; Chromatography, Liquid; Diabetes Mellitus; Diabetic Angiopathies; Humans; Limit of Detection; Lysine; Oxidative Stress; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Uremia	2014
Diffuse glomerular nodular lesions in diabetic pigs carrying a dominant-negative mutant hepatocyte nuclear factor 1-alpha, an inheritant diabetic gene in humans. PloS one, 2014, Volume: 9, Issue:3 Topics: Animals; Animals, Genetically Modified; Collagen; Diabetes Mellitus; Genes, Dominant; Glycation End Products, Advanced; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Immunohistochemistry; Inheritance Patterns; Kidney Glomerulus; Lysine; Mutation; Sus scrofa; Transforming Growth Factor beta	2014
Serum carboxymethyl-lysine, an advanced glycation end product, is associated with arterial stiffness in older adults. Journal of hypertension, 2015, Volume: 33, Issue:4 Topics: Aged; Aging; Aorta; Body Composition; Cardiovascular Diseases; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Hypertension; Inflammation; Linear Models; Lipoproteins, HDL; Logistic Models; Lysine; Male; Odds Ratio; Pulse Wave Analysis; Smoking; Vascular Stiffness	2015
Development of Diagnostic Fragment Ion Library for Glycated Peptides of Human Serum Albumin: Targeted Quantification in Prediabetic, Diabetic, and Microalbuminuria Plasma by Parallel Reaction Monitoring, SWATH, and MSE. Molecular & cellular proteomics : MCP, 2015, Volume: 14, Issue:8 Topics: Albuminuria; Amino Acid Sequence; Analysis of Variance; Diabetes Mellitus; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Lysine; Molecular Sequence Data; Peptide Library; Peptides; Prediabetic State; Serum Albumin; Tandem Mass Spectrometry	2015
Carboxymethyl lysine, an advanced glycation end product, and incident diabetes: a case-cohort analysis of the ARIC Study. Diabetic medicine : a journal of the British Diabetic Association, 2016, Volume: 33, Issue:10 Topics: Atherosclerosis; Case-Control Studies; Cohort Studies; Diabetes Mellitus; Diabetic Angiopathies; Female; Glycation End Products, Advanced; Humans; Incidence; Lysine; Male; Middle Aged; Risk Factors	2016
Nε-(carboxymethyl) lysine-induced mitochondrial fission and mitophagy cause decreased insulin secretion from β-cells. American journal of physiology. Endocrinology and metabolism, 2015, Nov-15, Volume: 309, Issue:10 Topics: Animals; Antioxidants; Biomarkers; Cell Line, Tumor; Diabetes Mellitus; Dietary Supplements; Down-Regulation; Glycation End Products, Advanced; Insulin; Insulin Secretion; Insulin-Secreting Cells; Lysine; Male; Mice, Inbred C57BL; Mice, Mutant Strains; Mitochondrial Dynamics; Mitophagy; Oxidants; Phagosomes; Rats; Receptor for Advanced Glycation End Products; Serum Albumin, Bovine; Thioctic Acid	2015
Advanced glycation end products and their circulating receptors predict cardiovascular disease mortality in older community-dwelling women. Aging clinical and experimental research, 2009, Volume: 21, Issue:2 Topics: Aged; Aging; Cardiovascular Diseases; Diabetes Mellitus; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Lysine; Predictive Value of Tests; Prospective Studies; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Renal Insufficiency; Residence Characteristics; Risk Factors	2009
Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study. Journal of vascular surgery, 2009, Volume: 50, Issue:3 Topics: Aged; Aortic Aneurysm, Abdominal; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus; Down-Regulation; Humans; Logistic Models; Lysine; Male; Men's Health; Odds Ratio; Risk Assessment; Risk Factors; Western Australia	2009
Regarding "Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study". Journal of vascular surgery, 2010, Volume: 52, Issue:2 Topics: Aortic Aneurysm, Abdominal; Biomarkers; Diabetes Mellitus; Down-Regulation; Humans; Lysine; Male; Men's Health; Predictive Value of Tests	2010
Relationship of a dominant advanced glycation end product, serum carboxymethyl-lysine, and abnormal glucose metabolism in adults: the Baltimore Longitudinal Study of Aging. The journal of nutrition, health & aging, 2010, Volume: 14, Issue:7 Topics: Aged; Baltimore; Blood Glucose; Diabetes Mellitus; Female; Glucose Intolerance; Glucose Tolerance Test; Glycation End Products, Advanced; Humans; Logistic Models; Lysine; Male; Middle Aged	2010
Relationship between advanced glycation end products and increased lipid peroxidation in semen of diabetic men. Diabetes research and clinical practice, 2011, Volume: 91, Issue:1 Topics: Adult; Antioxidants; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Infertility, Male; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Semen; Spermatozoa; Thiobarbituric Acid Reactive Substances; Young Adult	2011
Dietary intake associated with serum versus urinary carboxymethyl-lysine, a major advanced glycation end product, in adults: the Energetics Study. European journal of clinical nutrition, 2012, Volume: 66, Issue:1 Topics: Adult; Aged; Atherosclerosis; Diabetes Mellitus; Diet; Female; Glycation End Products, Advanced; Humans; Kidney Diseases; Lysine; Male; Middle Aged; Young Adult	2012
Are advanced glycation end products cardiovascular risk factors in patients with CRF? American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 41, Issue:3 Suppl 1 Topics: Adult; Aged; Aged, 80 and over; Arginine; Cardiovascular Diseases; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Hypertrophy, Left Ventricular; Imidazoles; Kidney Failure, Chronic; Kidney Transplantation; Lysine; Male; Middle Aged; Renal Dialysis; Retrospective Studies; Risk Factors	2003
The amino-terminal domains of the ezrin, radixin, and moesin (ERM) proteins bind advanced glycation end products, an interaction that may play a role in the development of diabetic complications. The Journal of biological chemistry, 2003, Jul-11, Volume: 278, Issue:28 Topics: Animals; Binding Sites; Biosensing Techniques; Blood Proteins; Blotting, Western; Cattle; Chromatography, Affinity; Cloning, Molecular; Cytoskeletal Proteins; Detergents; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glycation End Products, Advanced; Humans; Kidney; Ligands; Lysine; Membrane Proteins; Microfilament Proteins; Phosphoproteins; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; Serum Albumin; Time Factors; Tumor Cells, Cultured; Tyrosine	2003
Impairment of vascular endothelial nitric oxide synthase activity by advanced glycation end products. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:10 Topics: Animals; Antibodies; Aorta; Arginine; Blood Pressure; Cells, Cultured; Citrulline; Diabetes Mellitus; Endothelium, Vascular; Enzyme Inhibitors; Female; Femoral Artery; Glycation End Products, Advanced; Humans; In Vitro Techniques; Lysine; Male; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rabbits; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Vasodilation	2003
Increased levels of advanced glycation end products in human cataractous lenses. Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:5 Topics: Aged; Antibodies, Monoclonal; Arginine; Cataract; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Imidazoles; Immunoenzyme Techniques; Lens, Crystalline; Lysine; Middle Aged; Oxidation-Reduction	2003
Dietary glycotoxins correlate with circulating advanced glycation end product levels in renal failure patients. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:3 Topics: Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus; Diet; Diet Records; Food Analysis; Food Handling; Glycation End Products, Advanced; Humans; Hypertension; Kidney Failure, Chronic; Lysine; Metabolic Clearance Rate; New York City; Peritoneal Dialysis; Pyruvaldehyde; Renal Dialysis; Smoking; Surveys and Questionnaires; Uremia	2003
Modification of proteins in vitro by physiological levels of glucose: pyridoxamine inhibits conversion of Amadori intermediate to advanced glycation end-products through binding of redox metal ions. The Journal of biological chemistry, 2003, Nov-21, Volume: 278, Issue:47 Topics: Animals; Carbon Isotopes; Diabetes Mellitus; Glucose; Glycation End Products, Advanced; Humans; Lysine; Metals; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Protein Processing, Post-Translational; Proteins; Pyridoxamine	2003
Advanced glycation end product ligands for the receptor for advanced glycation end products: biochemical characterization and formation kinetics. Analytical biochemistry, 2004, Jan-01, Volume: 324, Issue:1 Topics: Acetaldehyde; Amines; Arginine; Diabetes Mellitus; Fructose; Glucose; Glycation End Products, Advanced; Glyoxylates; Humans; Ligands; Lysine; Membrane Proteins; Molecular Weight; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Recombinant Proteins; Regression Analysis; Ribose; Serum Albumin, Bovine; Spectrometry, Fluorescence	2004
N epsilon-carboxymethyllysine in brain aging, diabetes mellitus, and Alzheimer's disease. Free radical biology & medicine, 2004, May-15, Volume: 36, Issue:10 Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Cytoplasm; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Neurofibrillary Tangles; Neurons; Plaque, Amyloid; tau Proteins	2004
Increased accumulation of the glycoxidation product Nepsilon-(carboxymethyl)lysine in hearts of diabetic patients: generation and characterisation of a monoclonal anti-CML antibody. Biochimica et biophysica acta, 2004, Mar-22, Volume: 1636, Issue:2-3 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Infant, Newborn; Lysine; Male; Myocardium; Oxidation-Reduction	2004
Aminoguanidine and metformin prevent the reduced rate of HDL-mediated cell cholesterol efflux induced by formation of advanced glycation end products. The international journal of biochemistry & cell biology, 2006, Volume: 38, Issue:3 Topics: Albumins; Animals; Atherosclerosis; Cells, Cultured; Cholesterol, HDL; Diabetes Mellitus; Enzyme Inhibitors; Glycation End Products, Advanced; Guanidines; Humans; Hypoglycemic Agents; Lysine; Macrophages, Peritoneal; Metformin; Mice	2006
Oxidation and carboxy methyl lysine-modification of albumin: possible involvement in the progression of oxidative stress in hemodialysis patients. Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Arginine; Blood Proteins; Case-Control Studies; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Imidazoles; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Neutrophils; Norleucine; Oxidative Stress; Protein Carbonylation; Pyrroles; Renal Dialysis; Respiratory Burst; Serum Albumin	2005
Identification of CML-modified proteins in hemofiltrate of diabetic patients by proteome analysis. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2008, Volume: 116, Issue:1 Topics: Antibodies; Antibodies, Monoclonal; Antibody Specificity; Blood Proteins; Diabetes Mellitus; Electrophoresis, Gel, Two-Dimensional; Glycation End Products, Advanced; Glycosylation; Hemofiltration; Humans; Immunoblotting; Lysine; Proteome; Sequence Analysis, Protein	2008
Advanced glycation end products accumulate in the reproductive tract of men with diabetes. International journal of andrology, 2009, Volume: 32, Issue:4 Topics: Adult; Blotting, Western; Case-Control Studies; Diabetes Complications; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Epididymis; Glycation End Products, Advanced; Humans; Immunohistochemistry; Infertility, Male; Lysine; Male; Semen; Spermatozoa; Testis	2009
L-arginine reduces heart collagen accumulation in the diabetic db/db mouse. Circulation, 1994, Volume: 90, Issue:1 Topics: Animals; Arginine; Collagen; Diabetes Mellitus; Hydroxyproline; Isomerism; Lysine; Mice; Mice, Mutant Strains; Myocardium; Tyrosine	1994
Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging. The Journal of clinical investigation, 1997, Feb-01, Volume: 99, Issue:3 Topics: Adult; Aged; Aging; Antibodies; Arteries; Arteriosclerosis; Biomarkers; Blood Proteins; Catalase; Child; Deferoxamine; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Fetus; Foam Cells; Guanidines; Humans; Immunohistochemistry; Intervertebral Disc; Intestinal Mucosa; Kidney; Lung; Lysine; Middle Aged; Molecular Structure; Myocardium; Oxidation-Reduction; Oxidative Stress; Pregnancy; Skin; Superoxide Dismutase; Thioctic Acid; Time Factors; Vitamin E	1997
Age-dependent increase in ortho-tyrosine and methionine sulfoxide in human skin collagen is not accelerated in diabetes. Evidence against a generalized increase in oxidative stress in diabetes. The Journal of clinical investigation, 1997, Aug-15, Volume: 100, Issue:4 Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arginine; Child; Child, Preschool; Collagen; Diabetes Mellitus; Glucose; Humans; Infant; Infant, Newborn; Lysine; Methionine; Middle Aged; Oxidative Stress; Skin; Time Factors; Tyrosine	1997
Pharmacological modulation of AGEs: a unique role for redox-active metal ions. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 1999, Volume: 19 Suppl 2 Topics: Animals; Antioxidants; Chelating Agents; Diabetes Mellitus; Glycation End Products, Advanced; Guanidines; Humans; Kidney Failure, Chronic; Lysine; Metals; Oxidation-Reduction; Oxidative Stress; Peritoneal Dialysis; Uremia	1999
N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression. The Journal of biological chemistry, 1999, Oct-29, Volume: 274, Issue:44 Topics: Animals; Diabetes Mellitus; Endothelium, Vascular; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Lung; Lysine; Mice; Mice, Inbred BALB C; Muscle, Smooth, Vascular; NF-kappa B; Phagocytes; Protein Binding; Protein Processing, Post-Translational; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Renal Insufficiency; Serum Albumin; Signal Transduction; Vascular Cell Adhesion Molecule-1	1999
Oxygen is not required for the browning and crosslinking of protein by pentoses: relevance to Maillard reactions in vivo. The international journal of biochemistry & cell biology, 1999, Volume: 31, Issue:11 Topics: Aging; Animals; Antioxidants; Arabinose; Arginine; Cattle; Cross-Linking Reagents; Diabetes Mellitus; Fluorescence; Glucose; In Vitro Techniques; Lysine; Maillard Reaction; Oxidation-Reduction; Oxygen; Pentoses; Proteins; Ribonucleases	1999
Advanced glycation end products in diabetic corneas. Investigative ophthalmology & visual science, 2000, Volume: 41, Issue:2 Topics: Aged; Aged, 80 and over; Animals; Antibodies, Monoclonal; Basement Membrane; Cell Adhesion; Collagen; Corneal Diseases; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Female; Glucose-6-Phosphate; Glycation End Products, Advanced; Glycosylation; Humans; Immunoenzyme Techniques; Laminin; Lysine; Male; Mice; Middle Aged	2000
Maillard reactions by alpha-oxoaldehydes: detection of glyoxal-modified proteins. Biochimica et biophysica acta, 2000, Sep-29, Volume: 1481, Issue:2 Topics: Aged; Aging; Antibodies; Cataract; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Glyoxal; Humans; Lens, Crystalline; Lysine; Maillard Reaction; Proteins; Serum Albumin; Serum Albumin, Bovine; Serum Albumin, Human	2000
Plasma levels of advanced glycation end products in healthy, long-term vegetarians and subjects on a western mixed diet. European journal of nutrition, 2001, Volume: 40, Issue:6 Topics: Adult; Aging; Diabetes Mellitus; Diet; Diet, Vegetarian; Edible Grain; Enzyme-Linked Immunosorbent Assay; Fabaceae; Fluorescence; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Kidney; Lysine	2001
Urinary carboxymethyl-lysine measurement as a potential indicator of diabetic complications. Biochemical Society transactions, 1989, Volume: 17, Issue:6 Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creatinine; Diabetes Complications; Diabetes Mellitus; Humans; Lysine; Male	1989