n(6)-carboxymethyllysine has been researched along with Diabetes Mellitus, Type 2 in 69 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (11.59) | 18.2507 |
| 2000's | 24 (34.78) | 29.6817 |
| 2010's | 33 (47.83) | 24.3611 |
| 2020's | 4 (5.80) | 2.80 |
| Authors | Studies |
|---|---|
| Bhadada, SK; Goni, VG; Karn, S; Kumar, N; Mehandia, V; Neradi, D; Pal, R; Rao, SD; Sharma, S; Sihota, P; Yadav, RN | 1 |
| Chen, QJ; Chen, S; Dai, Y; Ding, FH; Li, FF; Li, LY; Lu, L; Shen, WF; Shen, Y; Wang, XQ; Wu, ZM | 1 |
| Balakrishna, S; Dias, CG; Venkataswamy, L | 1 |
| Cardelo, MP; de la Cruz-Ares, S; García-Rios, A; Gutiérrez-Mariscal, FM; Katsiki, N; López-Miranda, J; Malagón, MM; Pérez-Martínez, P; Torres-Peña, JD; Yubero-Serrano, EM | 1 |
| Clifton, PM; Keogh, JB; Kim, Y | 1 |
| Amouzegar, A; Azizi, F; Hedayati, M; Mirmiran, P; Sahranavard, S; Talaei, B | 1 |
| Furey, A; Likhodii, S; Liu, M; Randell, EW; Sun, G; Zhai, G; Zhang, W | 1 |
| Bao, Z; Dai, Z; Jing, L; Li, L; Shao, C; Sun, Z; Wang, Z; Xu, S; Yan, J; Ye, F; Zhu, J | 1 |
| Clifton, PM; Deo, P; Keogh, JB; Price, NJ | 1 |
| An, X; Liu, J; Liu, S; Xu, W; Yu, J; Yu, X; Zhao, Y | 1 |
| Ahmad, B; Chiew, Y; Kadir, KA; Tan, SMQ | 1 |
| Dekker, JM; Engelen, L; Ferreira, I; Hanssen, NM; Huijberts, MS; Nijpels, G; Schalkwijk, CG; Scheijen, JL; Stehouwer, CD; van der Kallen, CJ; van Greevenbroek, MM | 1 |
| Barzilay, JI; Fonseca, V; Goldfine, AB; Jablonski, KA; Monnier, VM; Shoelson, SE; Strauch, C | 1 |
| Aubert, CE; Bourron, O; Fonfrede, M; Gillery, P; Hartemann, A; Jaisson, S; Michel, PL; Morel, F | 1 |
| Chen, WC; Lee, MR; Lee, WJ; Liang, KW; Lin, LY; Lin, SY; Liu, SH; Shen, CC; Sheu, ML; Sheu, WH; Tien, HR; Tsai, YC; Yang, TJ; Yeh, HY; Yi, YC | 1 |
| Poretsky, L; Striker, GE; Vlassara, H; Woodward, M; Yubero-Serrano, EM | 1 |
| Jing, Z; Kuang, L; Liu, N; Yang, J | 1 |
| Brismar, K; Kärvestedt, L; Malmstedt, J; Swedenborg, J | 1 |
| Khanna, VK; Kruzliak, P; Meyer, CH; Mishra, N; Saxena, S; Shukla, RK; Singh, V | 1 |
| Ge, YS; Lin, YZ; Liu, Y; Sha, L; Shen, QF; Sun, CK; Wang, C; Xu, HZ; Zhang, JH | 1 |
| He, J; Jing, Z; Kuang, L; Liu, N; Sun, Z; Wang, Y; Yang, J | 1 |
| Gaspar, L; Khanna, V; Kruzliak, P; Mishra, N; Prasad, S; Ruia, S; Saxena, S; Singh, V; Staffa, R | 1 |
| Brunner-La Rocca, HP; Dekker, JM; Henry, RM; Linssen, PB; Nijpels, G; Schalkwijk, CG; Stehouwer, CD | 1 |
| Beelman, RB; Cai, W; Calvo, MS; Goh, BC; Kalaras, MD; Mehrotra, A; Nadkarni, G; Uribarri, J; Wang, L | 1 |
| Andican, A; Andican, G; Burcak, G; Kurt, A; Siva, ZO | 1 |
| Beisswenger, PJ; Howell, S; Knowler, WC; Lemley, KV; Mauer, M; Nelson, RG; Saulnier, PJ; Tanamas, SK; Weil, EJ; Wheelock, KM; Yee, B | 1 |
| Berriche, O; Bouzidi, H; Haddad, M; Hammami, M; Kerkeni, M; Knani, I | 1 |
| Bahn, G; Beisswenger, PJ; Howell, S; Reaven, PD; Saremi, A; Schwenke, DC | 1 |
| Grossin, N; Guillausseau, PJ; Massin, P; Meas, T; Wautier, JL; Wautier, MP | 1 |
| An, XF; Gao, F; Gu, WJ; Huang, S; Liu, JS; Ten, SC; Wang, X; Yu, JY; Zhao, Y | 1 |
| Burrell, LM; Cooper, ME; Coughlan, MT; Forbes, JM; Jerums, G; MacIsaac, RJ; Patel, SK; Penfold, SA; Sourris, KC; Srivastava, PM; Steer, D; Thomas, MC; Webster, DE | 1 |
| Kang, KS; Kim, HY; Park, JH; Yamabe, N; Yokozawa, T | 1 |
| Cai, W; Chen, X; Mericq, V; Piccardo, C; Striker, GE; Uribarri, J; Vlassara, H; Zhu, L | 1 |
| Kang, KS; Noh, JS; Park, CH; Shibahara, N; Tanaka, T; Yamabe, N; Yokozawa, T | 1 |
| Engelen, L; Ferreira, I; Hovind, P; Parving, HH; Persson, F; Rossing, P; Schalkwijk, CG; Stehouwer, CD; Teerlink, T | 1 |
| Basta, G; Del Turco, S; Gastaldelli, A; Navarra, T | 1 |
| Matsui, J; Matsuki, K; Matsumura, K; Murakami, H; Suda, T; Tamasawa, N; Tanabe, J; Yamashita, M | 1 |
| Bhadhuri, G; Bhattacharya, B; Choudhuri, S; Chowdhury, IH; Dutta, D; Mitra, B; Mondal, LK; Saha, A; Sen, A | 1 |
| Abd el Baki, RF; Andrassy, M; Bierhaus, A; Dugi, KA; Haering, HU; Hamann, A; Kasper, M; Kloeting, I; Mentz, S; Merz, W; Morcos, M; Nawroth, PP; Sayed, AA; Schleicher, E; Schmidt, AM; Schwenger, V; Stern, D; Tritschler, H; van der Woude, F; Waldherr, R; Yard, B; Ziegler, R | 1 |
| Berg, TJ; Birkeland, KI; Brownlee, M; Giardino, I; Hanssen, KF; Kilhovd, BK; Thornalley, PJ; Torjesen, PA | 1 |
| Aoyama, I; Enomoto, A; Nakamura, S; Niwa, T; Tachikawa, T; Takayama, F; Tobita, K | 1 |
| Boulanger, E; Guillausseau, PJ; Huijberts, M; Laloi-Michelin, M; Levy, B; Massin, P; Wautier, JL; Wautier, MP | 1 |
| Braun, A; Busch, M; Fleck, C; Franke, S; Müller, A; Müller, UA; Schiel, R; Stein, G | 1 |
| Hirata, K; Kubo, K | 1 |
| Bierhaus, A; Haslbeck, KM; Haslbeck, M; Heuss, D; Nawroth, P; Neundörfer, B; Schleicher, E | 1 |
| Baynes, JW; Bleich, M; Busch, AE; Deemer, EK; Dingermann, T; Huber, J; Münch, G; Schäfer, S; Schmid, K; Somoza, V; Wihler, C | 1 |
| Busch, AE; Huber, J; Linz, W; Rütten, H; Schäfer, S; Wihler, C | 1 |
| Gonzalez-Reche, LM; Kraus, T; Kucharczyk, A; Musiol, AK | 1 |
| Basta, G; Buzzigoli, E; Casolaro, A; Del Turco, S; Ferrannini, E; Gastaldelli, A; Lazzerini, G; Natali, A; Sironi, AM | 1 |
| Brandstädt, A; Busch, M; Franke, S; Gerth, J; Hunsicker, LG; Ott, U; Stein, G; Wolf, G | 1 |
| Aoki, T; Gohda, T; Hagiwara, S; Horikoshi, S; Ito, T; Kaneko, S; Matsumoto, M; Murakoshi, M; Tanimoto, M; Tomino, Y; Yamada, K | 1 |
| Baatz, JE; Baynes, JW; Bethard, J; Blatnik, M; Brock, JW; Frizzell, N; Nagai, R; Thorpe, SR; Walla, MD | 1 |
| Heine, RJ; Niessen, HW; Schalkwijk, CG; Simsek, S; van Deutekom, AW | 1 |
| Busch, M; Franke, S; Rohde, RD; Stein, G; Wolf, G | 1 |
| Bailie, KE; Baynes, JW; Dunn, JA; Dyer, DG; Lyons, TJ; McCance, DR; Thorpe, SR | 1 |
| Horiuchi, S; Ikeda, K; Inomuta, H; Ishibashi, T; Murata, T; Nagai, R | 1 |
| Horie, K; Kurokawa, K; Maeda, K; Miyata, S; Miyata, T; Monnier, VM; Sakai, H; Sugiyama, S; van Ypersole de Strihou, C; Witztum, JL | 1 |
| Horiuchi, S; Nishizawa, Y; Sugimoto, K; Yagihashi, S | 1 |
| LePage, K; Newkirk, MM; Niwa, T; Rubin, L | 1 |
| Daimon, M; Eguchi, H; Hirata, A; Igarashi, M; Kato, T; Manaka, H; Ohnuma, H; Ono, Y; Saito, T; Yamaguchi, H | 1 |
| Kameda, Y; Koike, T; Makita, Z; Takeuchi, M; Yanagisawa, K | 1 |
| Berg, TJ; Birkeland, KI; Hanssen, KF; Kilhovd, BK; Thorsby, P | 1 |
| Danielsson, R; Fogarty, JF; Frank, A; Monnier, VM; Sell, DR | 1 |
| Bucala, R; Kameda, Y; Koike, T; Makita, Z; Suzuki, T; Takeuchi, M | 1 |
| Karimian-Teherani, D; Melling, M; Menzel, EJ; Pfeiler, W; Schnallinger, M; Sobal, G; Zangerle, C | 1 |
| Hamada, Y; Horiuchi, S; Hotta, N; Kasuya, Y; Kato, K; Komori, T; Nagai, R; Nakamura, J; Naruse, K | 1 |
| Albano, E; Allochis, G; Bellomo, G; Cusaro, C; Mottaran, E; Rolla, R; Vay, D; Vidali, M | 1 |
| Endo, M; Higuchi, M; Koike, T; Makita, Z; Matsuda, A; Matsushita, T; Okamoto, T; Takeuchi, M; Tsuchida, K; Yanagisawa, K | 1 |
| Heidland, A; Kientsch-Engel, R; Mazák, I; Nagy, J; Schinzel, R; Wagner, Z; Wittmann, I | 1 |
11 trial(s) available for n(6)-carboxymethyllysine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Endothelial Dysfunction and Advanced Glycation End Products in Patients with Newly Diagnosed Versus Established Diabetes: From the CORDIOPREV Study.
Topics: Biomarkers; Carotid Artery Diseases; Coronary Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diet, Healthy; Endothelium, Vascular; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Olive Oil; Pyruvaldehyde; Single-Blind Method; Vasodilation | 2020 |
Effects of Two Different Dietary Patterns on Inflammatory Markers, Advanced Glycation End Products and Lipids in Subjects without Type 2 Diabetes: A Randomised Crossover Study.
Topics: Adult; Biomarkers; Cholesterol; Cross-Over Studies; Diabetes Mellitus, Type 2; Diet, Healthy; Diet, Western; Feeding Behavior; Female; Food Handling; Glycation End Products, Advanced; Humans; Inflammation; Insulin Resistance; Lipids; Lysine; Male; Middle Aged; Plasminogen Inactivators; Reference Values; Triglycerides; Young Adult | 2017 |
Effects of Cinnamon Consumption on Glycemic Indicators, Advanced Glycation End Products, and Antioxidant Status in Type 2 Diabetic Patients.
Topics: Aged; Antioxidants; Blood Glucose; Cinnamomum zeylanicum; Diabetes Mellitus, Type 2; Double-Blind Method; Glycated Hemoglobin; Glycation End Products, Advanced; Homeostasis; Humans; Insulin; Lysine; Malondialdehyde; Middle Aged | 2017 |
The improvement of oxidative stress by two proprietary herbal medicines in type 2 diabetes.
Topics: Aged; Biomarkers; Blood Pressure; Diabetes Mellitus, Type 2; Dinoprost; Drugs, Chinese Herbal; Female; Ginkgo biloba; Humans; Lysine; Male; Middle Aged; Oxidative Stress; Plant Extracts | 2018 |
Tocotrienol-Rich Vitamin E from Palm Oil (Tocovid) and Its Effects in Diabetes and Diabetic Nephropathy: A Pilot Phase II Clinical Trial.
Topics: Aged; Albuminuria; Biomarkers; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Kidney; Lysine; Malaysia; Male; Middle Aged; Pilot Projects; Prospective Studies; Time Factors; Tocotrienols; Treatment Outcome | 2018 |
The impact of salsalate treatment on serum levels of advanced glycation end products in type 2 diabetes.
Topics: Adiponectin; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Pyruvaldehyde; Salicylates | 2014 |
Effects of sevelamer carbonate on advanced glycation end products and antioxidant/pro-oxidant status in patients with diabetic kidney disease.
Topics: Adiponectin; Age Factors; Aged; Albuminuria; Chelating Agents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dinoprost; Estrogen Receptor alpha; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Intention to Treat Analysis; Lysine; Male; Metformin; Middle Aged; NF-E2-Related Factor 2; Pyruvaldehyde; Receptor for Advanced Glycation End Products; Receptors, Tumor Necrosis Factor, Type I; RNA, Messenger; Sevelamer; Sex Factors; Single-Blind Method; Sirtuin 1; White People | 2015 |
Advanced Glycation End Products Predict Loss of Renal Function and Correlate With Lesions of Diabetic Kidney Disease in American Indians With Type 2 Diabetes.
Topics: Adult; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Imidazoles; Indians, North American; Kidney; Kidney Glomerulus; Losartan; Lysine; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Pyruvaldehyde | 2016 |
Irbesartan treatment does not influence plasma levels of the advanced glycation end products N(epsilon)(1-carboxymethyl)lysine and N(epsilon)(1-carboxyethyl)lysine in patients with type 2 diabetes and microalbuminuria. A randomized controlled trial.
Topics: Adult; Aged; Albuminuria; Angiotensin Receptor Antagonists; Biomarkers; Biphenyl Compounds; Diabetes Complications; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glycation End Products, Advanced; Humans; Hypertension; Irbesartan; Lysine; Male; Middle Aged; Prognosis; Tetrazoles | 2011 |
Serum levels of the advanced glycation end products Nepsilon-carboxymethyllysine and pentosidine are not influenced by treatment with the angiotensin receptor II type 1 blocker irbesartan in patients with type 2 diabetic nephropathy and hypertension.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arginine; Biphenyl Compounds; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Hypertension; Irbesartan; Linear Models; Lysine; Male; Middle Aged; Statistics, Nonparametric; Tetrazoles | 2008 |
Serum levels of advanced glycation end products are increased in patients with type 2 diabetes and coronary heart disease.
Topics: Aged; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Epitopes; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Multivariate Analysis; Risk Factors | 1999 |
58 other study(ies) available for n(6)-carboxymethyllysine and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Can fingernail quality predict bone damage in Type 2 diabetes mellitus? a pilot study.
Topics: Aged; Arthroplasty, Replacement, Hip; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Femoral Neck Fractures; Femur Neck; Humans; Lysine; Middle Aged; Nails; Osteoporosis, Postmenopausal; Pilot Projects; Spectroscopy, Fourier Transform Infrared; X-Ray Microtomography | 2021 |
High serum levels of N-epsilon-carboxymethyllysine are associated with poor coronary collateralization in type 2 diabetic patients with chronic total occlusion of coronary artery.
Topics: Collateral Circulation; Coronary Angiography; Coronary Circulation; Coronary Occlusion; Coronary Vessels; Diabetes Mellitus, Type 2; Humans; Lysine | 2022 |
Diabetic nephropathy patients show hyper-responsiveness to N6-carboxymethyllysine.
Topics: Culture Media, Conditioned; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Lysine; NF-kappa B | 2022 |
Hyperglycemia-related advanced glycation end-products is associated with the altered phosphatidylcholine metabolism in osteoarthritis patients with diabetes.
Topics: Aged; Biomarkers; Chromatography, Liquid; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Hyperglycemia; Lysine; Male; Middle Aged; Osteoarthritis; Phosphatidylcholines; Synovial Fluid; Tandem Mass Spectrometry | 2017 |
CML/CD36 accelerates atherosclerotic progression via inhibiting foam cell migration.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; CD36 Antigens; Cell Migration Inhibition; Cell Movement; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Foam Cells; Glycation End Products, Advanced; Lysine; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Plaque, Atherosclerotic; RAW 264.7 Cells | 2018 |
Effects of Weight Loss on Advanced Glycation End Products in Subjects with and without Diabetes: A Preliminary Report.
Topics: Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Overweight; Prediabetic State; Weight Loss | 2017 |
Plasma levels of advanced glycation endproducts Nε-(carboxymethyl)lysine, Nε-(carboxyethyl)lysine, and pentosidine are not independently associated with cardiovascular disease in individuals with or without type 2 diabetes: the Hoorn and CODAM studies.
Topics: Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Lysine; Male; Middle Aged | 2013 |
Association of peripheral neuropathy with circulating advanced glycation end products, soluble receptor for advanced glycation end products and other risk factors in patients with type 2 diabetes.
Topics: Aged; Arterial Occlusive Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Neuropathies; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Paris; Peripheral Nervous System; Prevalence; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors; Severity of Illness Index; Sex Factors; Solubility; Waist Circumference | 2014 |
Nε-carboxymethyllysine-mediated endoplasmic reticulum stress promotes endothelial cell injury through Nox4/MKP-3 interaction.
Topics: Animals; Apoptosis; Cell Line, Transformed; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Dual Specificity Phosphatase 6; Endoplasmic Reticulum Stress; Endothelial Cells; Gene Expression Regulation; Humans; Lysine; Male; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; NADPH Oxidase 4; NADPH Oxidases; Protein Binding; RNA, Small Interfering; Signal Transduction | 2014 |
LC-MS/MS for the simultaneous determination of polar endogenous ADMA and CML in plasma and urine from diabetics.
Topics: Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Linear Models; Lysine; Retrospective Studies; Tandem Mass Spectrometry | 2015 |
The receptor for advanced glycation end products and risk of peripheral arterial disease, amputation or death in type 2 diabetes: a population-based cohort study.
Topics: Aged; Amputation, Surgical; Biomarkers; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Progression; Disease-Free Survival; Female; Humans; Incidence; Kaplan-Meier Estimate; Lysine; Male; Middle Aged; Peripheral Arterial Disease; Proportional Hazards Models; Receptor for Advanced Glycation End Products; Risk Assessment; Risk Factors; S100A12 Protein; Sweden; Time Factors | 2015 |
Association of serum N(ε)-Carboxy methyl lysine with severity of diabetic retinopathy.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Humans; Lysine; Male; Middle Aged; Severity of Illness Index | 2016 |
Nε-(carboxymethyl)-lysine, White Matter, and Cognitive Function in Diabetes Patients.
Topics: Aged; Anisotropy; Case-Control Studies; Cognition Disorders; Diabetes Mellitus, Type 2; Diffusion Magnetic Resonance Imaging; Female; Humans; Image Processing, Computer-Assisted; Leukoencephalopathies; Lysine; Male; Mental Status Schedule; Neuropsychological Tests | 2016 |
ADMA: a specific biomarker for pathologic progress in diabetic microvascular complications?
Topics: Adult; Aged; Area Under Curve; Arginine; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Logistic Models; Lysine; Male; Middle Aged; Odds Ratio; Prediabetic State; ROC Curve; Tandem Mass Spectrometry | 2016 |
Increased levels of N(ε)- Carboxy methyl lysine (N(ε)-CML) are associated with topographic alterations in retinal pigment epithelium: A preliminary study.
Topics: Adult; Biomarkers; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Progression; Female; Glycated Hemoglobin; Humans; Lysine; Male; Middle Aged; Prospective Studies; Regression Analysis; Retinal Pigment Epithelium; Severity of Illness Index; Tertiary Care Centers; Up-Regulation; Vitreoretinopathy, Proliferative | 2016 |
Serum advanced glycation endproducts are associated with left ventricular dysfunction in normal glucose metabolism but not in type 2 diabetes: The Hoorn Study.
Topics: Aged; Arginine; Biomarkers; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Echocardiography; Female; Glycation End Products, Advanced; Humans; Linear Models; Lysine; Male; Middle Aged; Myocardial Contraction; Netherlands; Predictive Value of Tests; Prognosis; Risk Assessment; Risk Factors; Ventricular Dysfunction, Left; Ventricular Function, Left | 2016 |
A Retrospective Study in Adults with Metabolic Syndrome: Diabetic Risk Factor Response to Daily Consumption of Agaricus bisporus (White Button Mushrooms).
Topics: Adiponectin; Adult; Agaricus; Antioxidants; beta-Glucans; Biomarkers; Body Mass Index; Chitin; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diet; Dinoprost; Ergothioneine; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Insulin Resistance; Leptin; Linear Models; Lysine; Male; Metabolic Syndrome; Middle Aged; Multivariate Analysis; Oxidative Stress; Polyphenols; Pyruvaldehyde; Retrospective Studies; Risk Factors; Triglycerides; Vitamin D | 2016 |
The effects of n-3 long-chain polyunsaturated fatty acid supplementation on AGEs and sRAGE in type 2 diabetes mellitus.
Topics: Aged; Animals; Arginine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Dietary Supplements; Fasting; Fatty Acids, Omega-3; Female; Gene Expression Regulation; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Lysine; Male; Middle Aged; NF-kappa B; Receptor for Advanced Glycation End Products; Signal Transduction; Waist Circumference | 2016 |
Plasma Levels of Pentosidine, Carboxymethyl-Lysine, Soluble Receptor for Advanced Glycation End Products, and Metabolic Syndrome: The Metformin Effect.
Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Hypoglycemic Agents; Lysine; Male; Metabolic Syndrome; Metformin; Middle Aged; Prognosis; Receptor for Advanced Glycation End Products | 2016 |
Advanced Glycation End Products, Oxidation Products, and the Extent of Atherosclerosis During the VA Diabetes Trial and Follow-up Study.
Topics: Aged; Atherosclerosis; Blood Glucose; Carotid Intima-Media Thickness; Cholesterol; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Oxidation-Reduction; Pyruvaldehyde; Triglycerides | 2017 |
Severity of diabetic microvascular complications is associated with a low soluble RAGE level.
Topics: Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2008 |
Plasma sRAGE is not associated with urinary microalbumin excretion in type 2 diabetic nephropathy at the early stage.
Topics: Age of Onset; Aged; Albuminuria; Blood Glucose; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme-Linked Immunosorbent Assay; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Lipids; Lysine; Male; Middle Aged; Patient Selection; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2010 |
Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy.
Topics: Aged; Antibodies, Neutralizing; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme-Linked Immunosorbent Assay; Female; HMGB1 Protein; Humans; Ligands; Lysine; Male; Middle Aged; Molecular Weight; Protein Kinase C-alpha; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Transcription, Genetic | 2010 |
Effects of heat-processed ginseng and its active component ginsenoside 20(S)-Rg3 on the progression of renal damage and dysfunction in type 2 diabetic Otsuka Long-Evans Tokushima Fatty rats.
Topics: Animals; Antioxidants; Blood Glucose; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Ginsenosides; Glycation End Products, Advanced; Hypoglycemic Agents; Kidney; Kidney Diseases; Lipid Peroxidation; Lipids; Lysine; Male; Nitric Oxide Synthase Type II; Oxidative Stress; Panax; Phytotherapy; Plant Extracts; Proteinuria; Rats; Rats, Inbred OLETF; Thiobarbituric Acid Reactive Substances | 2010 |
Maternally transmitted and food-derived glycotoxins: a factor preconditioning the young to diabetes?
Topics: Adiponectin; Adolescent; Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Infant; Infant Food; Infant, Newborn; Insulin; Isoprostanes; Lysine; Pyruvaldehyde; Risk Factors; Young Adult | 2010 |
Evaluation of loganin, iridoid glycoside from Corni Fructus, on hepatic and renal glucolipotoxicity and inflammation in type 2 diabetic db/db mice.
Topics: Animals; Biomarkers; Body Weight; Cholesterol; Cornus; Cyclooxygenase 2; Diabetes Mellitus, Type 2; Drinking; Fatty Acids; Gene Expression Regulation, Enzymologic; Glucose; Glycation End Products, Advanced; Hematologic Tests; Inflammation; Iridoids; Kidney; Lipid Metabolism; Liver; Lysine; Male; Mice; Nitric Oxide Synthase Type II; Organ Size; Oxidative Stress; PPAR alpha; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Transcription Factor RelA; Triglycerides | 2010 |
Protective role of adiponectin on endothelial dysfunction induced by AGEs: a clinical and experimental approach.
Topics: Adiponectin; Adult; Cells, Cultured; Diabetes Mellitus, Type 2; E-Selectin; Endothelial Cells; Endothelium, Vascular; Female; Glucose Tolerance Test; Glycation End Products, Advanced; Humans; Insulin Resistance; Lysine; Male; Middle Aged; Vascular Cell Adhesion Molecule-1 | 2011 |
Reduction of paraoxonase-1 activity may contribute the qualitative impairment of HDL particles in patients with type 2 diabetes.
Topics: Aged; Apolipoprotein A-I; Aryldialkylphosphatase; Atherosclerosis; Biological Transport; Biomarkers; Cell Line; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hyperglycemia; Lipoproteins, HDL; Lysine; Macrophages; Male; Middle Aged; Serum Amyloid A Protein | 2013 |
Role of N-ε- carboxy methyl lysine, advanced glycation end products and reactive oxygen species for the development of nonproliferative and proliferative retinopathy in type 2 diabetes mellitus.
Topics: Adult; Aged; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Glycation End Products, Advanced; Humans; Leukocytes, Mononuclear; Lysine; Male; Middle Aged; Reactive Oxygen Species; Sulfhydryl Compounds; Vitreous Body | 2013 |
Activation of tubular epithelial cells in diabetic nephropathy.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Epithelium; Glycation End Products, Advanced; Humans; Kidney; Kidney Tubules; Lysine; NF-kappa B; Rats; Rats, Brattleboro; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reference Values; Serum Albumin; Transcription, Genetic; Urine | 2002 |
Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes.
Topics: Diabetes Mellitus, Type 2; Humans; Imidazoles; Immunoassay; Lysine; Pyruvaldehyde; Sensitivity and Specificity | 2003 |
An inhibitor of advanced glycation end product formation reduces N epsilon-(carboxymethyl)lysine accumulation in glomeruli of diabetic rats.
Topics: Age Factors; Animals; Antibodies, Monoclonal; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Fluorescent Antibody Technique, Indirect; Glomerular Mesangium; Glycation End Products, Advanced; Kidney; Kidney Glomerulus; Lysine; Rats; Rats, Inbred OLETF; Rats, Inbred Strains; Thiadiazoles; Thiazolidines | 2003 |
N(carboxymethyl)lysine as a biomarker for microvascular complications in type 2 diabetic patients.
Topics: Biomarkers; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Microcirculation; Middle Aged | 2003 |
Effect of smoking on risk factors for cardiovascular disease in patients with diabetes mellitus and renal insufficiency.
Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Homocysteine; Humans; Kidney Transplantation; Lysine; Middle Aged; Renal Dialysis; Renal Insufficiency; Risk Factors; Smoking | 2003 |
Relationship between blood levels of N-carboxymethyl-lysine and pentosidine and the severity of microangiopathy in type 2 diabetes.
Topics: Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged | 2004 |
The AGE/RAGE/NF-(kappa)B pathway may contribute to the pathogenesis of polyneuropathy in impaired glucose tolerance (IGT).
Topics: Aged; Biopsy; Charcot-Marie-Tooth Disease; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Glucose Intolerance; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; NF-kappa B; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Sural Nerve | 2005 |
Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and vasopeptidase inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Ascorbic Acid; Blood Glucose; Chromatography, High Pressure Liquid; Creatine; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; Glycation End Products, Advanced; Heterocyclic Compounds, 3-Ring; Kidney; Lysine; Male; Oxidation-Reduction; Protease Inhibitors; Ramipril; Rats; Rats, Zucker; Spectrometry, Fluorescence | 2005 |
Impaired left ventricular relaxation in type 2 diabetic rats is related to myocardial accumulation of N(epsilon)-(carboxymethyl) lysine.
Topics: Animals; Biomarkers; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Lysine; Male; Myocardial Contraction; Myocardium; Rats; Rats, Zucker; Severity of Illness Index; Ventricular Dysfunction, Left | 2006 |
Determination of N epsilon-(carboxymethyl)lysine in exhaled breath condensate using isotope dilution liquid chromatography/electrospray ionization tandem mass spectrometry.
Topics: Aged; Biomarkers; Breath Tests; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Pneumonia; Pulmonary Disease, Chronic Obstructive; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2006 |
Circulating soluble receptor for advanced glycation end products is inversely associated with glycemic control and S100A12 protein.
Topics: Adult; Aged; Blood Glucose; Blood Pressure; C-Reactive Protein; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Inflammation Mediators; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Risk Factors; S100 Proteins; S100A12 Protein; Statistics as Topic | 2006 |
The advanced glycation end product N(epsilon)-carboxymethyllysine is not a predictor of cardiovascular events and renal outcomes in patients with type 2 diabetic kidney disease and hypertension.
Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Disease Progression; Female; Glycation End Products, Advanced; Humans; Hypertension; Lysine; Male; Middle Aged; Multivariate Analysis; Oxidative Stress; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Risk Factors | 2006 |
Effect of pyridoxamine (K-163), an inhibitor of advanced glycation end products, on type 2 diabetic nephropathy in KK-A(y)/Ta mice.
Topics: Animals; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Glycation End Products, Advanced; Immunohistochemistry; Laminin; Lysine; Male; Mice; Pyridoxamine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schiff Bases; Transforming Growth Factor beta1; Tyrosine | 2007 |
Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress.
Topics: 3T3 Cells; Adipocytes; Adipogenesis; Adipose Tissue; Animals; Biomarkers; Cell Differentiation; Citric Acid Cycle; Cysteine; Diabetes Complications; Diabetes Mellitus, Type 2; Fibroblasts; Fumarates; Humans; Insulin Resistance; Lysine; Mice; Mitochondria; Obesity; Protein Processing, Post-Translational; Risk Factors; Stress, Physiological; Succinic Acid; Sulfhydryl Compounds | 2007 |
Increased Nepsilon-(carboxymethyl)-lysine levels in cerebral blood vessels of diabetic patients and in a (streptozotocin-treated) rat model of diabetes mellitus.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Brain; Cerebrovascular Circulation; Child; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Rats; Rats, Wistar | 2008 |
Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Collagen; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Humans; Lysine; Maillard Reaction; Male; Microcirculation; Middle Aged; Skin | 1993 |
The relationship between accumulation of advanced glycation end products and expression of vascular endothelial growth factor in human diabetic retinas.
Topics: Aged; Aged, 80 and over; Antibodies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Endothelial Growth Factors; Epitopes; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lymphokines; Lysine; Male; Middle Aged; Retina; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1997 |
Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.
Topics: Adolescent; Adult; Aged; Animals; Antibodies; Arginine; Collagen; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Kidney Glomerulus; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Mice; Middle Aged; Nephrotic Syndrome; Norleucine; Pyrroles; Rabbits | 1997 |
Localization in human diabetic peripheral nerve of N(epsilon)-carboxymethyllysine-protein adducts, an advanced glycation endproduct.
Topics: Aged; Diabetes Mellitus, Type 2; Female; Fluorescent Antibody Technique; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Lysine; Male; Microscopy, Immunoelectron; Middle Aged; Nerve Fibers, Myelinated; Peripheral Nerves; Proteins | 1997 |
Advanced glycation endproducts (AGE) on IgG, a target for circulating antibodies in North American Indians with rheumatoid arthritis (RA).
Topics: Adult; Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoantibodies; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Glycosylation; Humans; Imidazoles; Immunoblotting; Immunoglobulin G; Immunoglobulin Heavy Chains; Immunoglobulin M; Indians, North American; Lysine; Male; Middle Aged; Nitroblue Tetrazolium; Ontario; Rheumatoid Factor | 1998 |
Increased serum levels of pentosidine, but not carboxymethyl lysine, in type 2 diabetes without obvious diabetic nephropathy.
Topics: Albuminuria; Arginine; Biomarkers; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Reference Values | 1999 |
Detection of noncarboxymethyllysine and carboxymethyllysine advanced glycation end products (AGE) in serum of diabetic patients.
Topics: Animals; Antibodies; Cattle; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Peptides; Rabbits; Renal Dialysis | 1999 |
A syndrome of molybdenosis, copper deficiency, and type 2 diabetes in the moose population of south-west Sweden.
Topics: Animals; Arginine; Case-Control Studies; Copper; Deer; Deficiency Diseases; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Kidney; Liver; Lysine; Molybdenum; Sweden | 2000 |
Immunological evidence that non-carboxymethyllysine advanced glycation end-products are produced from short chain sugars and dicarbonyl compounds in vivo.
Topics: Animals; Antibodies; Cattle; Chromatography, Affinity; Cross Reactions; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glyceraldehyde; Glyoxal; Humans; Immunoblotting; Kidney Failure, Chronic; Lysine; Maillard Reaction; Oxidation-Reduction; Pyruvaldehyde; Rabbits; Renal Dialysis | 2000 |
Differential scanning calorimetry, biochemical, and biomechanical analysis of human skin from individuals with diabetes mellitus.
Topics: Aged; Aged, 80 and over; Anisotropy; Biomechanical Phenomena; Calorimetry, Differential Scanning; Collagen; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Lysine; Protein Denaturation; Skin | 2000 |
Epalrestat, an aldose reductase ihibitor, reduces the levels of Nepsilon-(carboxymethyl)lysine protein adducts and their precursors in erythrocytes from diabetic patients.
Topics: Aldehyde Reductase; Blood Glucose; Blood Proteins; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retinopathy; Enzyme Inhibitors; Erythrocytes; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Reference Values; Rhodanine; Thiazolidines | 2000 |
Antibodies against advanced glycation end product Nepsilon-(carboxymethyl)lysine in healthy controls and diabetic patients.
Topics: Adult; Aged; Autoantibodies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Glycation End Products, Advanced; Humans; Immunoglobulin G; Lysine; Male; Middle Aged; Serum Albumin | 2000 |
Increased levels of vascular endothelial growth factor and advanced glycation end products in aqueous humor of patients with diabetic retinopathy.
Topics: Aged; Aqueous Humor; Biomarkers; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Endothelial Growth Factors; Female; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lymphokines; Lysine; Male; Middle Aged; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
N(epsilon)-(carboxymethyl)lysine levels in patients with type 2 diabetes: role of renal function.
Topics: Adult; Aged; Aged, 80 and over; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Oxidative Stress | 2001 |