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n(6)-carboxymethyllysine and Complications of Diabetes Mellitus

n(6)-carboxymethyllysine has been researched along with Complications of Diabetes Mellitus in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's2 (7.41)18.2507
2000's12 (44.44)29.6817
2010's10 (37.04)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Boulanger, É; Delguste, F; Foligné, B; Fremont, M; Garat, A; Guilbaud, A; Howsam, M; Lestavel, S; Maboudou, P; Niquet-Léridon, C; Onraed, B; Schraen, S; Tessier, FJ1
Ahmad, S; Akashah, R; Alouffi, S; Faisal, M; Khan, M; Khan, MS; Khan, S; Shahab, U1
Blasetti Fantauzzi, C; Cappello, P; de Latouliere, L; Iacobini, C; Ionta, V; Manni, I; Menini, S; Novelli, F; Pesce, C; Piaggio, G; Pugliese, G1
Moroishi, N; Nagai, M; Nagai, R; Ohno, R; Shirakawa, J1
He, W; Hu, S; Liu, Z; Ma, G; Xu, H; Yan, G1
Kumar, PA; Menon, RK; Raghu, G; Reddy, GB; Saleem, MA; Welsh, GI1
Fujiwara, Y; Ikeda, T; Miyashita, H; Nagai, R; Nakashima, K; Yoshimitsu, H1
Fujiwara, Y; Ikeda, T; Kiyota, N; Motomura, K; Nagai, R; Nohara, T; Takeya, M; Tsurushima, K1
Hur, JM; Kang, KS; Yamabe, N; Yokozawa, T1
Agbaje, I; Czerwiec, A; Glenn, J; Mallidis, C; McClure, N; O'Neill, J; Stitt, A1
Andrades, ME; Bortolin, RC; Dal-Pizzol, F; Lorenzi, R; Moreira, JC; Nagai, R1
Amiri, I; Goodarzi, MT; Karimi, J; Khodadadi, I; Tavilani, H1
Engelen, L; Ferreira, I; Hovind, P; Parving, HH; Persson, F; Rossing, P; Schalkwijk, CG; Stehouwer, CD; Teerlink, T1
Akileshwari, C; Muthenna, P; Reddy, GB1
Cai, W; Crandall, J; Dardaine, V; Goldberg, T; Oberstein, R; Peppa, M; Rayfield, EJ; Vlassara, H1
Bach, LA; Cooper, ME; Gallicchio, M; Jerums, G; McRobert, EA1
Baliga, S; Cai, W; Goldberg, T; Lu, M; Peppa, M; Uribarri, J; Vassalotti, JA; Vlassara, H1
Kopeć, J1
Appel, T; Franke, S; Kientsch-Engel, R; Müller, UA; Ross, IS; Schiel, R; Stein, G; Voigt, U1
Hwang, JS; Shin, CH; Yang, SW1
Andrassy, M; Bierhaus, A; Chen, J; Franke, S; Kientsch-Engel, R; Morcos, M; Nawroth, PP; Rudofsky, G; Schiekofer, S; Schleicher, E; Schneider, JG; Stein, G; von Eynatten, M; Wendt, T1
Bierhaus, A; Haslbeck, KM; Haslbeck, M; Hecht, M; Heuss, D; Nawroth, P; Neundörfer, B; Pauli, E; Schleicher, E; Schlötzer-Schrehardtt, U1
Baatz, JE; Baynes, JW; Bethard, J; Blatnik, M; Brock, JW; Frizzell, N; Nagai, R; Thorpe, SR; Walla, MD1
Agbaje, IM; Atkinson, AB; Glenn, JV; Mallidis, C; McClure, N; Pringle, R; Rogers, DA; Steger, K; Stitt, AW1
Bailey, AJ; Paul, RG1
Ahmed, MU; Baynes, JW; Brinkmann, E; Litchfield, JE; Reddy, S; Thorpe, SR; Wells-Knecht, KJ; Wells-Knecht, MC; Zyzak, DV1
Ah-Sing, E; Gould, BJ; Stace, BC; Walsh, DP; Wright, J1

Reviews

4 review(s) available for n(6)-carboxymethyllysine and Complications of Diabetes Mellitus

ArticleYear
Inhibition of AGEs formation by natural products.
    Amino acids, 2014, Volume: 46, Issue:2

    Topics: Animals; Biological Products; Carbohydrate Metabolism; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lipid Metabolism; Lysine

2014
[Carbonyl stress significance in the pathogenesis of dialysis-related amyloidosis].
    Przeglad lekarski, 2003, Volume: 60, Issue:6

    Topics: Amyloidosis; Diabetes Complications; Humans; Kidney Diseases; Lysine; Oxidative Stress; Renal Dialysis

2003
Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes.
    The international journal of biochemistry & cell biology, 1996, Volume: 28, Issue:12

    Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Elastin; Glycation End Products, Advanced; Glycosylation; Humans; Imidazoles; Lysine; Maillard Reaction; Malondialdehyde; Norleucine; Pyrroles

1996
New biomarkers of Maillard reaction damage to proteins.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11 Suppl 5

    Topics: Aging; Arginine; Biomarkers; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Lysine; Maillard Reaction; Molecular Structure; Norleucine; Oxidation-Reduction; Proteins; Pyrroles

1996

Trials

3 trial(s) available for n(6)-carboxymethyllysine and Complications of Diabetes Mellitus

ArticleYear
Irbesartan treatment does not influence plasma levels of the advanced glycation end products N(epsilon)(1-carboxymethyl)lysine and N(epsilon)(1-carboxyethyl)lysine in patients with type 2 diabetes and microalbuminuria. A randomized controlled trial.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:11

    Topics: Adult; Aged; Albuminuria; Angiotensin Receptor Antagonists; Biomarkers; Biphenyl Compounds; Diabetes Complications; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glycation End Products, Advanced; Humans; Hypertension; Irbesartan; Lysine; Male; Middle Aged; Prognosis; Tetrazoles

2011
Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Nov-26, Volume: 99, Issue:24

    Topics: Biomarkers; C-Reactive Protein; Cross-Over Studies; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Female; Food Analysis; Food, Formulated; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Inflammation Mediators; Lipid Peroxidation; Lysine; Male; Middle Aged; Pyruvaldehyde; Risk Factors; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2002
Improvement of the quality of diabetes control and decrease in the concentrations of AGE-products in patients with type 1 and insulin-treated type 2 diabetes mellitus: results from a 10 year-prospective, population-based survey on the quality of diabetes
    European journal of medical research, 2004, Aug-31, Volume: 9, Issue:8

    Topics: Adolescent; Adult; Arginine; Creatinine; Diabetes Complications; Diabetes Mellitus; Female; Germany; Glycation End Products, Advanced; Health Surveys; Humans; Insulin; Longitudinal Studies; Lysine; Male; Middle Aged; Prospective Studies; Time Factors

2004

Other Studies

20 other study(ies) available for n(6)-carboxymethyllysine and Complications of Diabetes Mellitus

ArticleYear
The Effect of Lactobacillus fermentum ME-3 Treatment on Glycation and Diabetes Complications.
    Molecular nutrition & food research, 2020, Volume: 64, Issue:6

    Topics: Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Gastrointestinal Microbiome; Glycated Hemoglobin; Glycation End Products, Advanced; Kidney; Limosilactobacillus fermentum; Lipids; Liver; Lysine; Male; Probiotics; Receptors, Leptin; Weight Gain

2020
Gold Nanoparticle-Bioconjugated Aminoguanidine Inhibits Glycation Reaction: An
    BioMed research international, 2021, Volume: 2021

    Topics: Animals; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycation End Products, Advanced; Glycosylation; Gold; Guanidines; Lysine; Male; Metal Nanoparticles; Proteins; Pyruvaldehyde; Rats; Rats, Wistar

2021
The advanced glycation end-product N
    The Journal of pathology, 2018, Volume: 245, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma in Situ; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Diabetes Complications; Disease Models, Animal; Disease Progression; Genes, ras; Humans; Lysine; Mice, Inbred C57BL; Mice, Transgenic; Pancreatic Neoplasms; Peptides; Receptor for Advanced Glycation End Products; Risk Factors; Signal Transduction; Time Factors; Tumor Burden; Xenograft Model Antitumor Assays

2018
The influence of disease and age on human cardiac stem cells.
    Annals of clinical biochemistry, 2014, Volume: 51, Issue:Pt 5

    Topics: Adolescent; Adult; Age Factors; Aged; Cells, Cultured; Child; Child, Preschool; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus; Flow Cytometry; Humans; Infant; Lysine; Middle Aged; Myocardium; Myocytes, Cardiac; Proto-Oncogene Proteins c-kit; Stem Cells; Young Adult

2014
Carboxymethyl lysine induces EMT in podocytes through transcription factor ZEB2: Implications for podocyte depletion and proteinuria in diabetes mellitus.
    Archives of biochemistry and biophysics, 2016, Jan-15, Volume: 590

    Topics: Animals; Cell Movement; Cells, Cultured; Diabetes Complications; Dose-Response Relationship, Drug; Epithelial-Mesenchymal Transition; Glycation End Products, Advanced; Homeodomain Proteins; Humans; Kidney; Lysine; NF-kappa B; Podocytes; Proteinuria; Rats; Rats, Wistar; Repressor Proteins; Zinc Finger E-box Binding Homeobox 2

2016
Two new prenylflavonoids from Epimedii Herba and their inhibitory effects on advanced glycation end-products.
    Journal of natural medicines, 2016, Volume: 70, Issue:2

    Topics: Animals; Arginine; Diabetes Complications; Drugs, Chinese Herbal; Epimedium; Flavonoids; Glycation End Products, Advanced; Lysine; Male; Phytotherapy; Plant Components, Aerial; Prenylation; Rats

2016
Astragalosides isolated from the root of astragalus radix inhibit the formation of advanced glycation end products.
    Journal of agricultural and food chemistry, 2009, Sep-09, Volume: 57, Issue:17

    Topics: Arginine; Astragalus Plant; Diabetes Complications; Glycation End Products, Advanced; Lysine; Plant Extracts; Plant Roots; Saponins; Triterpenes

2009
Matcha, a powdered green tea, ameliorates the progression of renal and hepatic damage in type 2 diabetic OLETF rats.
    Journal of medicinal food, 2009, Volume: 12, Issue:4

    Topics: Animals; Biomarkers; Blood Proteins; Camellia sinensis; Cholesterol; Diabetes Complications; Diabetes Mellitus, Experimental; Glucose; Glycation End Products, Advanced; Kidney; Liver; Lysine; Phytotherapy; Plant Extracts; Powders; Rats; Rats, Inbred OLETF; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin; Sterol Regulatory Element Binding Protein 2; Tea; Thiobarbiturates; Triglycerides

2009
Differences in mouse models of diabetes mellitus in studies of male reproduction.
    International journal of andrology, 2010, Oct-01, Volume: 33, Issue:5

    Topics: Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA Damage; Epididymis; Glycation End Products, Advanced; Infertility, Male; Lysine; Male; Mice; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Spermatozoa; Streptozocin; Testis

2010
Glycolaldehyde induces oxidative stress in the heart: a clue to diabetic cardiomyopathy?
    Cardiovascular toxicology, 2010, Volume: 10, Issue:4

    Topics: Acetaldehyde; Animals; Cardiomyopathies; Catalase; Diabetes Complications; Injections, Intravenous; Lactoylglutathione Lyase; Lipid Peroxidation; Lysine; Male; Myocardium; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Sulfhydryl Compounds; Superoxide Dismutase; Time Factors

2010
Relationship between advanced glycation end products and increased lipid peroxidation in semen of diabetic men.
    Diabetes research and clinical practice, 2011, Volume: 91, Issue:1

    Topics: Adult; Antioxidants; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Infertility, Male; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Semen; Spermatozoa; Thiobarbituric Acid Reactive Substances; Young Adult

2011
Ellagic acid, a new antiglycating agent: its inhibition of Nϵ-(carboxymethyl)lysine.
    The Biochemical journal, 2012, Feb-15, Volume: 442, Issue:1

    Topics: Animals; Crystallins; Diabetes Complications; Ellagic Acid; Gluconates; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lactones; Lens, Crystalline; Lysine; Male; Muramidase; Organ Culture Techniques; Rats; Rats, Wistar; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2012
The amino-terminal domains of the ezrin, radixin, and moesin (ERM) proteins bind advanced glycation end products, an interaction that may play a role in the development of diabetic complications.
    The Journal of biological chemistry, 2003, Jul-11, Volume: 278, Issue:28

    Topics: Animals; Binding Sites; Biosensing Techniques; Blood Proteins; Blotting, Western; Cattle; Chromatography, Affinity; Cloning, Molecular; Cytoskeletal Proteins; Detergents; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glycation End Products, Advanced; Humans; Kidney; Ligands; Lysine; Membrane Proteins; Microfilament Proteins; Phosphoproteins; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; Serum Albumin; Time Factors; Tumor Cells, Cultured; Tyrosine

2003
Dietary glycotoxins correlate with circulating advanced glycation end product levels in renal failure patients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2003, Volume: 42, Issue:3

    Topics: Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus; Diet; Diet Records; Food Analysis; Food Handling; Glycation End Products, Advanced; Humans; Hypertension; Kidney Failure, Chronic; Lysine; Metabolic Clearance Rate; New York City; Peritoneal Dialysis; Pyruvaldehyde; Renal Dialysis; Smoking; Surveys and Questionnaires; Uremia

2003
Clinical implications of N epsilon-(carboxymethyl)lysine, advanced glycation end product, in children and adolescents with type 1 diabetes.
    Diabetes, obesity & metabolism, 2005, Volume: 7, Issue:3

    Topics: Adolescent; Biomarkers; Case-Control Studies; Child; Chronic Disease; Diabetes Complications; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Linear Models; Lysine; Male

2005
Postprandial mononuclear NF-kappaB activation is independent of the AGE-content of a single meal.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2006, Volume: 114, Issue:4

    Topics: Active Transport, Cell Nucleus; Administration, Oral; Caseins; Cell Nucleus; Diabetes Complications; Food, Formulated; Glycation End Products, Advanced; Humans; Leukocytes, Mononuclear; Lysine; Male; NF-kappa B; Vascular Diseases

2006
Activation of the RAGE pathway: a general mechanism in the pathogenesis of polyneuropathies?
    Neurological research, 2007, Volume: 29, Issue:1

    Topics: Aged; Alcoholism; Biomarkers; Biopsy; Diabetes Complications; Humans; Leukocytes, Mononuclear; Lysine; Middle Aged; Peripheral Nerves; Polyneuropathies; Predictive Value of Tests; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Schwann Cells; Signal Transduction; Sural Nerve; Transcription Factor RelA; Vasculitis; Vitamin B 12 Deficiency

2007
Succination of protein thiols during adipocyte maturation: a biomarker of mitochondrial stress.
    The Journal of biological chemistry, 2007, Nov-23, Volume: 282, Issue:47

    Topics: 3T3 Cells; Adipocytes; Adipogenesis; Adipose Tissue; Animals; Biomarkers; Cell Differentiation; Citric Acid Cycle; Cysteine; Diabetes Complications; Diabetes Mellitus, Type 2; Fibroblasts; Fumarates; Humans; Insulin Resistance; Lysine; Mice; Mitochondria; Obesity; Protein Processing, Post-Translational; Risk Factors; Stress, Physiological; Succinic Acid; Sulfhydryl Compounds

2007
Advanced glycation end products accumulate in the reproductive tract of men with diabetes.
    International journal of andrology, 2009, Volume: 32, Issue:4

    Topics: Adult; Blotting, Western; Case-Control Studies; Diabetes Complications; Diabetes Mellitus; Enzyme-Linked Immunosorbent Assay; Epididymis; Glycation End Products, Advanced; Humans; Immunohistochemistry; Infertility, Male; Lysine; Male; Semen; Spermatozoa; Testis

2009
Urinary carboxymethyl-lysine measurement as a potential indicator of diabetic complications.
    Biochemical Society transactions, 1989, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, High Pressure Liquid; Creatinine; Diabetes Complications; Diabetes Mellitus; Humans; Lysine; Male

1989