n(6)-carboxymethyllysine has been researched along with Alloxan Diabetes in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (12.00) | 18.2507 |
| 2000's | 18 (36.00) | 29.6817 |
| 2010's | 22 (44.00) | 24.3611 |
| 2020's | 4 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, CW; Chung, YH; Ha, SK; Han, EH; Huh, YH; Hyon, JY; Jeong Ha, S; Jeong, HG; Jung, SK; Kim, HJ; Kim, Y; Lee, H; Lee, J; Min, JY; Park, J; Yun, SH | 1 |
| Boulanger, É; Delguste, F; Foligné, B; Fremont, M; Garat, A; Guilbaud, A; Howsam, M; Lestavel, S; Maboudou, P; Niquet-Léridon, C; Onraed, B; Schraen, S; Tessier, FJ | 1 |
| Ahmad, S; Akashah, R; Alouffi, S; Faisal, M; Khan, M; Khan, MS; Khan, S; Shahab, U | 1 |
| Liu, S; Wang, N; Wang, Y; Xu, P; Yao, W; Zhang, J; Zhang, Y | 1 |
| Bao, Z; Dai, Z; Jing, L; Li, L; Shao, C; Sun, Z; Wang, Z; Xu, S; Yan, J; Ye, F; Zhu, J | 1 |
| Kabata, K; Matsuda, S; Nagai, R; Shirakawa, JI; Sugawa, H | 1 |
| Liu, YT; Mong, MC; Pai, PY; Wang, ZH; Yang, YC; Yin, MC | 1 |
| Brouwers, O; de Vos-Houben, JM; Hageman, G; Janssen, BJ; Miyata, T; Niessen, PM; Schalkwijk, CG; Stehouwer, CD; van Nieuwenhoven, F | 1 |
| Chen, X; Li, L; Liang, Y; Liu, N; Wang, Z; Yan, J; Yuan, W | 1 |
| Chen, WC; Lee, MR; Lee, WJ; Liang, KW; Lin, LY; Lin, SY; Liu, SH; Shen, CC; Sheu, ML; Sheu, WH; Tien, HR; Tsai, YC; Yang, TJ; Yeh, HY; Yi, YC | 1 |
| Efstathiou, T; Gratas-Delamarche, A; Groussard, C; Lefeuvre-Orfila, L; Malardé, L; Vincent, S | 1 |
| Brimble, MA; Brings, S; Choong, YS; Cooper, GJ; Gong, D; Hogl, S; Kamalov, M; Middleditch, M; Zhang, S | 1 |
| Ho, JJ; Hsu, CC; Hsu, JY; Yang, HT; Yin, MC | 1 |
| Brings, S; Ejdesjö, A; Eriksson, UJ; Fleming, T; Fred, RG; Nawroth, PP | 1 |
| Gupta, D; Hansen, LM; Joseph, G; Taylor, WR; Weiss, D | 1 |
| Lin, CC; Yin, MC | 1 |
| Chang, CJ; Liou, SS; Liu, IM; Tzeng, TF | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Ozawa, Y | 1 |
| Hur, JM; Kang, KS; Yamabe, N; Yokozawa, T | 1 |
| Snow, LM; Thompson, LV | 1 |
| Agbaje, I; Czerwiec, A; Glenn, J; Mallidis, C; McClure, N; O'Neill, J; Stitt, A | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Ozawa, Y; Taguchi, K | 1 |
| Chen, CD; Chen, MH; Kao, SH; Lee, HM; Lo, MC; Lu, CI | 1 |
| Araki, T; Fujiwara, Y; Ikeda, T; Kiyota, N; Mera, K; Nagai, R; Nohara, T; Sakashita, N; Takeya, M; Tsurushima, K; Yoshitomi, M | 1 |
| Kim, CS; Kim, J; Kim, JS; Sohn, E | 1 |
| Coughlan, MT; Forbes, JM | 1 |
| de Assis, AM; Denardin, CC; Longoni, A; Moreira, JC; Pasquali, MA; Perry, ML; Rech, A; Rotta, LN; Souza, DO | 1 |
| An, Y; Chen, D; Jiang, Y; Liu, N; Ren, L; Wang, Z; Zhu, Y | 1 |
| Chen, WB; Jen, JF; Lee, MR; Lee, WJ; Liu, SH; Pan, HC; Shen, CC; Sheu, ML; Sheu, WH; Tien, HR; Yang, TJ; Yi, YC | 1 |
| Gao, C; Gao, E; Koch, W; Lau, WB; Lian, K; Liu, J; Liu, Y; Lu, X; Ma, Y; Qu, Y; Sun, L; Tao, L; Wang, H; Wang, R; Xia, C; Xu, A; Yang, L | 1 |
| Bidasee, KR; Kutty, S; Moore, CJ; Nagai, R; Shao, CH; Singh, J | 1 |
| Alderson, NL; Anderson, NL; Baynes, JW; Boyle, C; Canning, P; Chachich, M; Duffy, N; Frizzell, N; Gardiner, TA; Januszewski, AS; Stitt, A; Thorpe, SR | 1 |
| Brammar, G; Burns, WC; Cao, Z; Cooper, ME; Forbes, JM; MCLennan, SV; Twigg, SM | 1 |
| Bach, LA; Cooper, ME; Gallicchio, M; Jerums, G; McRobert, EA | 1 |
| Burns, WC; Cooper, ME; Forbes, JM; Founds, HW; Jerums, G; Thallas, V; Thomas, MC | 1 |
| Hagino, N; Horiuchi, S; Kobayashi, S; Nagai, R; Suzuki, M; Tsuneki, H | 1 |
| Cottalasso, D; Furfaro, AL; Marinari, UM; Menini, S; Odetti, P; Patriarca, S; Pesce, C; Pronzato, MA; Traverso, N | 1 |
| Arnstein, M; Cooper, ME; Coughlan, MT; Forbes, JM; Gasser, A; Long, DM; Pete, J; Thallas-Bonke, V; Thorpe, SR; Tong, DC | 1 |
| Bach, LA; Cooper, ME; Coughlan, MT; Forbes, JM; Fukami, K; Penfold, SA; Sourris, KC; Thallas-Bonke, V; Thorpe, SR; Yap, FY | 1 |
| Fujiwara, Y; Mera, K; Nagai, R; Sakashita, N; Takeya, M; Yamagata, K | 1 |
| Kang, KS; Kim, HY; Yamabe, N; Yokozawa, T | 1 |
| Heine, RJ; Niessen, HW; Schalkwijk, CG; Simsek, S; van Deutekom, AW | 1 |
| Katsuzaki, T; Niwa, T; Takei, Y; Tatemichi, N | 1 |
| Asano, T; Futata, T; Horiuchi, S; Ikeda, K; Meng, J; Myint, T; Nagai, R; Sakata, N; Takebayashi, S; Taniguchi, N | 1 |
| Monnier, VM; Obrenovich, M; Saxena, AK; Saxena, P; Weiss, MF; Wu, X | 1 |
| Abraham, EC; Green, K; Shaw, SM; Swamy-Mruthinti, S; Zhao, HR | 1 |
| Araki, N; Horiuchi, S; Nagai, R; Shibayama, R | 1 |
| Schmidt, AM; Stern, DM; Yan, SD; Yan, SF | 1 |
| Bitsch, I; Bretzel, RG; Federlin, KF; Geyer, J; Hammes, HP; Köpcke, W; Mavrakis, K; Netzel, M; Sauerland, C; Stracke, H; Werkmann, D | 1 |
| Höger, H; Lubec, B; Lubec, G; Szalay, S; Weninger, M; Xi, Z | 1 |
1 review(s) available for n(6)-carboxymethyllysine and Alloxan Diabetes
| Article | Year |
|---|---|
The biology of the receptor for advanced glycation end products and its ligands.
Topics: Amyloidosis; Animals; Capillary Permeability; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Endothelium, Vascular; Erythrocytes; Glycation End Products, Advanced; Humans; Ligands; Lung; Lysine; Membrane Proteins; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Amyloid A Protein; Tumor Cells, Cultured | 2000 |
49 other study(ies) available for n(6)-carboxymethyllysine and Alloxan Diabetes
| Article | Year |
|---|---|
Mitochondrial carnitine palmitoyltransferase 2 is involved in N
Topics: Animals; Blood Glucose; Carnitine O-Palmitoyltransferase; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Glycated Hemoglobin; Humans; Kidney; Lysine; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Mitochondria | 2020 |
The Effect of Lactobacillus fermentum ME-3 Treatment on Glycation and Diabetes Complications.
Topics: Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Gastrointestinal Microbiome; Glycated Hemoglobin; Glycation End Products, Advanced; Kidney; Limosilactobacillus fermentum; Lipids; Liver; Lysine; Male; Probiotics; Receptors, Leptin; Weight Gain | 2020 |
Gold Nanoparticle-Bioconjugated Aminoguanidine Inhibits Glycation Reaction: An
Topics: Animals; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycation End Products, Advanced; Glycosylation; Gold; Guanidines; Lysine; Male; Metal Nanoparticles; Proteins; Pyruvaldehyde; Rats; Rats, Wistar | 2021 |
Structural elucidation and anti-diabetic osteoporotic activity of an arabinogalactan from Phellodendron chinense Schneid.
Topics: Animals; Bone Density Conservation Agents; Diabetes Mellitus, Experimental; Galactans; Glycation End Products, Advanced; Glycoside Hydrolase Inhibitors; Hypoglycemic Agents; Lysine; Male; Osteoporosis; Phellodendron; Rats, Wistar; Receptor for Advanced Glycation End Products | 2021 |
CML/CD36 accelerates atherosclerotic progression via inhibiting foam cell migration.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; CD36 Antigens; Cell Migration Inhibition; Cell Movement; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Foam Cells; Glycation End Products, Advanced; Lysine; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Plaque, Atherosclerotic; RAW 264.7 Cells | 2018 |
[Preventive Effects of Aphanothece sacrum on Diabetic Cataracts].
Topics: Animals; Cataract; Cyanobacteria; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Glycation End Products, Advanced; Lens, Crystalline; Lysine; Male; Mice, Inbred Strains; Oxidative Stress; Streptozocin; Tandem Mass Spectrometry | 2019 |
Anti-Diabetic Effects of Gynura Bicolor Aqueous Extract in Mice.
Topics: Animals; Antidiuretic Agents; Arginine; Asteraceae; Blood Glucose; Diabetes Mellitus, Experimental; Glutathione; Humans; Kidney; Liver; Lysine; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Plant Extracts; Reactive Oxygen Species | 2019 |
Mild oxidative damage in the diabetic rat heart is attenuated by glyoxalase-1 overexpression.
Topics: Animals; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Experimental; Echocardiography; Fibrosis; Inflammation; Lactoylglutathione Lyase; Lysine; Myocardium; Oxidative Stress; Rats; Tandem Mass Spectrometry; Ventricular Remodeling | 2013 |
Effects of Nε-carboxymethyl-Lysine on ERS-mediated apoptosis in diabetic atherosclerosis.
Topics: Animals; Apoptosis; Atherosclerosis; Blood Glucose; Blotting, Western; Cholesterol; Diabetes Mellitus, Experimental; Endoplasmic Reticulum Stress; Glycation End Products, Advanced; Immunohistochemistry; Lysine; Male; Mice | 2014 |
Nε-carboxymethyllysine-mediated endoplasmic reticulum stress promotes endothelial cell injury through Nox4/MKP-3 interaction.
Topics: Animals; Apoptosis; Cell Line, Transformed; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Dual Specificity Phosphatase 6; Endoplasmic Reticulum Stress; Endothelial Cells; Gene Expression Regulation; Humans; Lysine; Male; Mice; Mice, Inbred C57BL; Molecular Targeted Therapy; NADPH Oxidase 4; NADPH Oxidases; Protein Binding; RNA, Small Interfering; Signal Transduction | 2014 |
Fermented soy permeate reduces cytokine level and oxidative stress in streptozotocin-induced diabetic rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dietary Supplements; Fermentation; Galactose; Glycine max; Inflammation; Interleukins; Isoflavones; Isoprostanes; Lysine; Male; Oligosaccharides; Oxidative Stress; Phytotherapy; Plant Extracts; Rats, Wistar; Superoxide Dismutase; Uric Acid | 2015 |
Diabetes-induced alterations in tissue collagen and carboxymethyllysine in rat kidneys: Association with increased collagen-degrading proteinases and amelioration by Cu(II)-selective chelation.
Topics: Animals; Chelating Agents; Collagen; Copper; Diabetes Mellitus, Experimental; Kidney; Lysine; Male; Peptide Hydrolases; Protein Processing, Post-Translational; Rats; Rats, Wistar; Streptozocin; Trientine | 2015 |
Houttuynia cordata aqueous extract attenuated glycative and oxidative stress in heart and kidney of diabetic mice.
Topics: Animals; Arginine; Blood Glucose; Blood Urea Nitrogen; Creatine Kinase; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fructose; Glutathione; Heart; Houttuynia; Insulin; Interleukin-6; Kidney; Lysine; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NADPH Oxidase 2; NADPH Oxidases; NF-kappa B; Oxidative Stress; Plant Extracts; Plant Leaves; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Tumor Necrosis Factor-alpha | 2016 |
Receptor for advanced glycation end products (RAGE) knockout reduces fetal dysmorphogenesis in murine diabetic pregnancy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dinoprost; Embryo, Mammalian; Embryonic Development; Female; Fetal Development; Fetal Resorption; Gene Expression; Liver; Lysine; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Pregnancy; Pregnancy in Diabetics; Pyruvaldehyde; Receptor for Advanced Glycation End Products | 2016 |
The receptor for advanced glycation end products impairs collateral formation in both diabetic and non-diabetic mice.
Topics: Animals; Blood Glucose; Collateral Circulation; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Glycation End Products, Advanced; Hindlimb; HMGB1 Protein; Immunoblotting; Immunohistochemistry; Ischemia; Lipids; Lysine; Male; Mice, Inbred C57BL; Mice, Knockout; Receptor for Advanced Glycation End Products | 2017 |
Antiglycative and anti-VEGF effects of s-ethyl cysteine and s-propyl cysteine in kidney of diabetic mice.
Topics: Albuminuria; Animals; Arginine; Blood Glucose; Creatinine; Cysteine; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Kidney; Lysine; Male; Mice; Mice, Inbred BALB C; Organ Size; Vascular Endothelial Growth Factor A | 2008 |
The amelioration of streptozotocin diabetes-induced renal damage by Wu-Ling-San (Hoelen Five Herb Formula), a traditional Chinese prescription.
Topics: Albuminuria; Animals; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drugs, Chinese Herbal; Fibronectins; Glycation End Products, Advanced; Hypoglycemic Agents; Kidney; Lysine; Magnoliopsida; Male; Mitochondria; NF-kappa B; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Thiobarbituric Acid Reactive Substances; Transforming Growth Factor beta1 | 2009 |
Effect of N-epsilon-(carboxymethyl)lysine on coronary vasoconstriction in isolated perfused hearts from control and streptozotocin-induced diabetic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium Channels; Coronary Vessels; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Disease Models, Animal; Drug Synergism; Glycation End Products, Advanced; In Vitro Techniques; Lysine; Male; Rats; Rats, Wistar; Stimulation, Chemical; Streptozocin; Superoxides; Vasoconstriction | 2009 |
Matcha, a powdered green tea, ameliorates the progression of renal and hepatic damage in type 2 diabetic OLETF rats.
Topics: Animals; Biomarkers; Blood Proteins; Camellia sinensis; Cholesterol; Diabetes Complications; Diabetes Mellitus, Experimental; Glucose; Glycation End Products, Advanced; Kidney; Liver; Lysine; Phytotherapy; Plant Extracts; Powders; Rats; Rats, Inbred OLETF; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin; Sterol Regulatory Element Binding Protein 2; Tea; Thiobarbiturates; Triglycerides | 2009 |
Influence of insulin and muscle fiber type in nepsilon-(carboxymethyl)-lysine accumulation in soleus muscle of rats with streptozotocin-induced diabetes mellitus.
Topics: Animals; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Image Processing, Computer-Assisted; Insulin; Lysine; Male; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Rats; Rats, Sprague-Dawley | 2009 |
Differences in mouse models of diabetes mellitus in studies of male reproduction.
Topics: Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Disease Models, Animal; DNA Damage; Epididymis; Glycation End Products, Advanced; Infertility, Male; Lysine; Male; Mice; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Spermatozoa; Streptozocin; Testis | 2010 |
Diabetes-associated changes and role of N epsilon-(carboxymethyl)lysine in big ET-1-induced coronary vasoconstriction.
Topics: Animals; Aspartic Acid Endopeptidases; Benzofurans; Blood Glucose; Body Weight; Coronary Vessels; Diabetes Mellitus, Experimental; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Glycopeptides; Heart; Lipids; Lysine; Male; Metalloendopeptidases; Myocardium; Oligopeptides; Organ Size; Organophosphonates; Peptides, Cyclic; Perfusion; Piperidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Thiorphan; Vasoconstriction | 2010 |
Glycoxidative stress-induced mitophagy modulates mitochondrial fates.
Topics: Animals; Cattle; Cell Death; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Hyperglycemia; Insulinoma; Lysine; Mice; Mitochondria; Models, Biological; Oxidative Stress; Phagosomes; Rats; Reactive Oxygen Species; Serum Albumin | 2010 |
Natural compounds containing a catechol group enhance the formation of Nε-(carboxymethyl)lysine of the Maillard reaction.
Topics: Animals; Catechols; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Free Radicals; Glutathione Peroxidase; Glycation End Products, Advanced; Glycosylation; Humans; Hydrogen Peroxide; Lysine; Macrophages; Maillard Reaction; Male; Mice; Mice, Inbred A; Oxidation-Reduction; Serum Albumin; Streptozocin; Structure-Activity Relationship | 2011 |
Elevated Nε-(carboxymethyl)lysine is associated with apoptosis of retinal pericytes in streptozotocin-induced diabetic rats.
Topics: Animals; Apoptosis; Caspase 3; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Fluorescent Antibody Technique, Indirect; Glycation End Products, Advanced; In Situ Nick-End Labeling; Lysine; NF-kappa B; Pericytes; Rats; Rats, Sprague-Dawley; Retinal Vessels | 2011 |
Temporal increases in urinary carboxymethyllysine correlate with albuminuria development in diabetes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Albuminuria; Animals; Biomarkers; Cytosol; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Gene Expression; Glomerular Filtration Rate; Glycation End Products, Advanced; Kidney Cortex; Lysine; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Streptozocin; Time Factors | 2011 |
Ω3-Polyunsaturated fatty acids prevent lipoperoxidation, modulate antioxidant enzymes, and reduce lipid content but do not alter glycogen metabolism in the livers of diabetic rats fed on a high fat thermolyzed diet.
Topics: Adiposity; Animals; Catalase; Diabetes Mellitus, Experimental; Diet, High-Fat; Fatty Acids, Omega-3; Glycation End Products, Advanced; Glycogen; Lipid Metabolism; Lipid Peroxidation; Liver; Lysine; Male; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2012 |
Advanced glycation end-product Nε-carboxymethyl-Lysine accelerates progression of atherosclerotic calcification in diabetes.
Topics: Alkaline Phosphatase; Animals; Apolipoproteins E; Apoptosis; Atherosclerosis; Blotting, Western; Bone Morphogenetic Protein 2; Cell Differentiation; Cell Line; Core Binding Factor Alpha 2 Subunit; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diet, High-Fat; Disease Progression; Glucose; Immunohistochemistry; Injections, Intravenous; Lipoproteins, LDL; Lysine; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Osteogenesis; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Staining and Labeling; Time Factors; Vascular Calcification | 2012 |
Advanced glycation end product Nε-carboxymethyllysine induces endothelial cell injury: the involvement of SHP-1-regulated VEGFR-2 dephosphorylation.
Topics: Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Gene Silencing; Glycation End Products, Advanced; Human Umbilical Vein Endothelial Cells; Humans; Lysine; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Reactive Oxygen Species; RNA, Small Interfering; Transfection; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
The alternative crosstalk between RAGE and nitrative thioredoxin inactivation during diabetic myocardial ischemia-reperfusion injury.
Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Free Radical Scavengers; Imines; Lysine; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide Synthase Type II; Organometallic Compounds; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Small Interfering; Salicylates; Superoxides; Thioredoxins; Tyrosine | 2012 |
Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) in diabetes.
Topics: Aldehydes; Animals; Arginine; Calcium; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Echocardiography; Guanidines; Lysine; Male; Malondialdehyde; Myocytes, Cardiac; Norleucine; Protein Carbonylation; Pyridoxamine; Pyrroles; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spin Labels | 2013 |
The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes.
Topics: Animals; Capillaries; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Extracellular Matrix; Female; Glycation End Products, Advanced; Laminin; Lysine; Pyridoxamine; Rats; Rats, Sprague-Dawley; Retina; Retinal Vessels; RNA, Messenger | 2002 |
Renal connective tissue growth factor induction in experimental diabetes is prevented by aminoguanidine.
Topics: Animals; Cells, Cultured; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibronectins; Gene Expression; Glomerular Mesangium; Glycation End Products, Advanced; Guanidines; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Lysine; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serum Albumin, Bovine | 2002 |
The amino-terminal domains of the ezrin, radixin, and moesin (ERM) proteins bind advanced glycation end products, an interaction that may play a role in the development of diabetic complications.
Topics: Animals; Binding Sites; Biosensing Techniques; Blood Proteins; Blotting, Western; Cattle; Chromatography, Affinity; Cloning, Molecular; Cytoskeletal Proteins; Detergents; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glycation End Products, Advanced; Humans; Kidney; Ligands; Lysine; Membrane Proteins; Microfilament Proteins; Phosphoproteins; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; Serum Albumin; Time Factors; Tumor Cells, Cultured; Tyrosine | 2003 |
The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes.
Topics: Albuminuria; Animal Population Groups; Animals; Blood Pressure; Collagen; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Glycation End Products, Advanced; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kidney; Kinetics; Lysine; Models, Biological; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine | 2003 |
Overproduction of N(epsilon)-(carboxymethyl)lysine-induced neovascularization in cultured choroidal explant of streptozotocin-diabetic rat.
Topics: Animals; Antibodies, Monoclonal; Choroid; Choroidal Neovascularization; Diabetes Mellitus, Experimental; Humans; Lysine; Male; Platelet-Derived Growth Factor; Rats; Rats, Wistar; Serum Albumin; Streptozocin; Time Factors; Tissue Culture Techniques; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2004 |
HNE-dependent molecular damage in diabetic nephropathy and its possible prevention by N-acetyl-cysteine and oxerutin.
Topics: Acetylcysteine; Aldehydes; Animals; Apoptosis; Cell Division; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycation End Products, Advanced; Hydroxyethylrutoside; Immunohistochemistry; Kidney Glomerulus; Lipid Peroxidation; Lysine; Male; Rats; Rats, Wistar; Taurine | 2005 |
Combination therapy with the advanced glycation end product cross-link breaker, alagebrium, and angiotensin converting enzyme inhibitors in diabetes: synergy or redundancy?
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cytosol; Diabetes Mellitus, Experimental; Drug Synergism; Drug Therapy, Combination; Enzyme Activation; Glycation End Products, Advanced; Kidney; Lysine; Male; Mitochondria; NF-kappa B; Oxidative Stress; Protein Kinase C; Ramipril; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Renin-Angiotensin System; Superoxide Dismutase; Thiazoles; Vascular Endothelial Growth Factor A | 2007 |
Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway.
Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glomerular Mesangium; Glycation End Products, Advanced; Lysine; Male; NADPH Oxidases; Protein Kinase C-alpha; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Superoxides | 2008 |
Immunochemical detection of Nepsilon-(carboxyethyl)lysine using a specific antibody.
Topics: Aldehydes; Animals; Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Reactions; Cattle; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Kidney; Lysine; Male; Pyruvaldehyde; Rats; Rats, Wistar; Sensitivity and Specificity; Serum Albumin | 2008 |
Role of maltol in advanced glycation end products and free radicals: in-vitro and in-vivo studies.
Topics: Animals; Blood Glucose; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Glycated Serum Albumin; Glycation End Products, Advanced; Guanidines; Lysine; Male; Proteinuria; Pyrones; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Serum Albumin; Streptozocin; Transcription Factor RelA | 2008 |
Increased Nepsilon-(carboxymethyl)-lysine levels in cerebral blood vessels of diabetic patients and in a (streptozotocin-treated) rat model of diabetes mellitus.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Brain; Cerebrovascular Circulation; Child; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Rats; Rats, Wistar | 2008 |
Hyperlipidemia and tissue contents of N epsilon-(carboxymethyl)lysine in streptozotocin diabetes.
Topics: Animals; Antibodies, Monoclonal; Cholesterol; Creatinine; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Hyperlipidemias; Lipids; Lipoproteins; Lysine; Male; Rats; Rats, Wistar; Triglycerides | 1997 |
Glycoxidation in aortic collagen from STZ-induced diabetic rats and its relevance to vascular damage.
Topics: Aldehydes; Animals; Aorta; Collagen; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Enzyme-Linked Immunosorbent Assay; Glycation End Products, Advanced; Glycosylation; Immunohistochemistry; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Streptozocin | 1998 |
Protein aging by carboxymethylation of lysines generates sites for divalent metal and redox active copper binding: relevance to diseases of glycoxidative stress.
Topics: Animals; Ascorbic Acid; Binding Sites; Biopolymers; Catalysis; Cations, Divalent; Collagen; Copper; Diabetes Mellitus, Experimental; Free Radicals; Glycation End Products, Advanced; Humans; Hydrogen Peroxide; Kidney Failure, Chronic; Lysine; Methylation; Oxidation-Reduction; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley; Serine | 1999 |
Evidence of a glycemic threshold for the development of cataracts in diabetic rats.
Topics: Animals; Blood Glucose; Cataract; Densitometry; Diabetes Mellitus, Experimental; Differential Threshold; Dose-Response Relationship, Drug; Fundus Oculi; Glycated Hemoglobin; Glycation End Products, Advanced; Lens, Crystalline; Lysine; Male; Rats; Rats, Sprague-Dawley; Streptozocin; Time Factors | 1999 |
Autoantibody against N(epsilon)-(carboxymethyl)lysine: an advanced glycation end product of the Maillard reaction.
Topics: Animals; Autoantibodies; Crystallins; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Epitopes; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction; Male; Rats; Rats, Wistar | 1999 |
Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Glycosylation; Lysine; Male; Neural Conduction; Oxidation-Reduction; Peripheral Nerves; Rats; Rats, Wistar; Reference Values; Thiamine; Time Factors | 2001 |
L-arginine reduces glomerular basement membrane collagen N epsilon-carboxymethyllysine in the diabetic db/db mouse.
Topics: Administration, Oral; Animals; Arginine; Basement Membrane; Collagen; Diabetes Mellitus, Experimental; Glycosylation; Kidney Glomerulus; Lysine; Mice; Mice, Mutant Strains | 1992 |