n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine and Disease Models, Animal

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship

Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship

Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Cartilage, Articular; Chondrocytes; Collagen Type II; Disease Models, Animal; Inflammation; Osteoarthritis; Rats; TOR Serine-Threonine Kinases

Topics: Adenosine; Adenosine A3 Receptor Antagonists; Animals; Anti-Inflammatory Agents; Apoptosis; Cartilage, Articular; Disease Models, Animal; Inflammation; Iodoacetates; Male; NF-kappa B; Osteoarthritis; Rats; Rats, Wistar; Signal Transduction

Topics: Adenosine; Administration, Oral; Animals; Biological Availability; Carcinoma; Cell Division; Colonic Neoplasms; Disease Models, Animal; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Purinergic P1 Receptor Agonists; Transplantation, Heterologous; Tumor Cells, Cultured

Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Antimetabolites, Antineoplastic; Cell Proliferation; Colonic Neoplasms; Colony-Forming Units Assay; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Mice; Mice, Inbred BALB C; Transplantation, Heterologous; Tumor Cells, Cultured

Topics: Adenosine; Analgesics; Animals; Chronic Pain; Disease Models, Animal; Inflammation; Male; Neuralgia; Rats; Rats, Wistar

Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Edema; Injections, Intraperitoneal; Lipase; Male; Necrosis; Pancreas; Pancreatic alpha-Amylases; Pancreatitis, Acute Necrotizing; Rats; Rats, Wistar; Receptor, Adenosine A3; Taurocholic Acid; Time Factors

Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Antineoplastic Agents, Phytogenic; Cytokines; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Hyperalgesia; Male; NADP; Neuralgia; Neuroglia; NF-kappa B; Oxidation-Reduction; Paclitaxel; Rats; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord; Tumor Necrosis Factor-alpha

Topics: Adenosine; Animals; Disease Models, Animal; Hemodynamics; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardial Reperfusion Injury; Receptor, Adenosine A2A; Receptor, Adenosine A3

Topics: Adenosine; Adenosine A3 Receptor Agonists; Analgesics; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Hyperalgesia; K Cl- Cotransporters; Male; Mice; Pain Threshold; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sciatica; Signal Transduction; Spinal Nerve Roots; Symporters; Thiazoles; Thioglycolates

Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Animals; Animals, Newborn; Apoptosis; Cell Survival; Disease Models, Animal; Excitatory Amino Acid Agonists; Fluorescent Antibody Technique, Indirect; In Situ Nick-End Labeling; Intravitreal Injections; Male; N-Methylaspartate; Neuroprotection; Optic Nerve Injuries; Organ Culture Techniques; Rats; Rats, Wistar; Receptor, Adenosine A3; Retina; Retinal Degeneration; Retinal Neurons

Topics: Action Potentials; Adenosine; Animals; Blood Glucose; Body Weight; Diabetic Neuropathies; Disease Models, Animal; Eating; Hyperalgesia; Male; Mice; Muscle, Skeletal; Neural Conduction; NF-kappa B; Pain Threshold; Receptor, Adenosine A3; Sciatic Nerve; Spinal Cord; Streptozocin

Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Animals; Blood Pressure; Disease Models, Animal; In Vitro Techniques; Lung; Lung Compliance; Lung Diseases; Perfusion; Peroxidase; Piperidines; Protective Agents; Pulmonary Artery; Pulmonary Edema; Rabbits; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Reperfusion Injury; Tumor Necrosis Factor-alpha

Topics: Adenosine; Anesthesia; Animals; Cardiotonic Agents; Coronary Circulation; Disease Models, Animal; Dogs; Iodine Radioisotopes; Myocardial Infarction; Myocardial Reperfusion Injury; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A3; Receptors, Purinergic P1

Topics: Adenosine; Animals; Chemokine CCL4; Chemokine CXCL2; Chemokines; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Interleukin-1; Interleukin-12; Interleukin-6; Macrophage Inflammatory Proteins; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Mice, Knockout; Peroxidase; Purinergic P1 Receptor Agonists; Receptor, Adenosine A3; Rectal Diseases; Weight Loss

Topics: Adenosine; Adenosine A2 Receptor Agonists; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Endotoxemia; Escherichia coli; Escherichia coli Infections; Female; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Purines; Receptors, Adenosine A2; Sepsis; Survival Analysis

Topics: Adenosine; Animals; Apoptosis; Cats; Disease Models, Animal; In Situ Nick-End Labeling; Lung; Lung Injury; Receptor, Adenosine A3; Reperfusion Injury

Topics: Adenosine; Adenosine A3 Receptor Agonists; Animals; Colitis; Disease Models, Animal; Free Radicals; Gene Expression Regulation; Glutathione Peroxidase; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Trinitrobenzenesulfonic Acid

Topics: Adenosine; Animals; Disease Models, Animal; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Phenylisopropyladenosine; Rabbits; Receptors, Purinergic; Stimulation, Chemical

Topics: Adenosine; Animals; Arthritis; Cells, Cultured; Chemokine CCL3; Chemokine CCL4; Collagen; Cytokines; Disease Models, Animal; Gene Expression; Macrophage Activation; Macrophage Inflammatory Proteins; Macrophages; Mice; Mice, Inbred DBA; Purinergic P1 Receptor Agonists; RNA, Messenger