Page last updated: 2024-10-31

n(1),n(11)-diethylnorspermine and Leukemia L 1210

n(1),n(11)-diethylnorspermine has been researched along with Leukemia L 1210 in 9 studies

N(1),N(11)-diethylnorspermine: structure given in first source

Research Excerpts

ExcerptRelevanceReference
" In the latter model, at a BE-3-3-3/cisplatin molar ratio of 250:1, an increased lifespan (ILS) of 56% is recorded during a 9-day dosing schedule, whereas BE-3-3-3 at the same dose caused a 21% ILS, and cisplatin only exhibited a 7% ILS."1.29Synergism of the polyamine analogue, N1,N11-bisethylnorspermine with cis-diaminedichloroplatinum (II) against murine neoplastic cell lines in vitro and in vivo. ( Austin, JK; Hawthorne, TR, 1996)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's6 (66.67)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bergeron, RJ6
McManis, JS3
Liu, CZ1
Feng, Y2
Weimar, WR5
Luchetta, GR1
Wu, Q2
Ortiz-Ocasio, J1
Vinson, JR2
Kramer, D1
Yao, GW1
Yao, H4
Sninsky, CA1
Raisler, B1
Gao, F1
Müller, R3
Zimmerman, CO1
McCosar, BH1
Smith, RE2
Bussenius, J1
Merriman, RL1
Huang, G1
Algee, SE1
Wiegand, J1
Hawthorne, TR2
Austin, JK1
Dorhout, B1
Kingma, AW1
de Hoog, E1
Muskiet, FA1
Felschow, DM1
Mi, Z1
Stanek, J1
Frei, J1
Porter, CW1
Beck, DE1
Ingeno, MJ1

Other Studies

9 other studies available for n(1),n(11)-diethylnorspermine and Leukemia L 1210

ArticleYear
Antiproliferative properties of polyamine analogues: a structure-activity study.
    Journal of medicinal chemistry, 1994, Oct-14, Volume: 37, Issue:21

    Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Binding, Competitive; Cell Division;

1994
Metabolically programmed polyamine analogue antidiarrheals.
    Journal of medicinal chemistry, 1996, Jun-21, Volume: 39, Issue:13

    Topics: Animals; Antidiarrheals; Biological Transport; Castor Oil; Cell Division; Computer Simulation; Diarr

1996
Effect of polyamine analogues on hypusine content in JURKAT T-cells.
    Journal of medicinal chemistry, 1998, Sep-24, Volume: 41, Issue:20

    Topics: Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Biological Transport; Cell Divisio

1998
Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives.
    Journal of medicinal chemistry, 2000, Jan-27, Volume: 43, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Division; Hydroxylation; Leukemia L1210; Magnetic Resonance Spe

2000
Synthesis and evaluation of hydroxylated polyamine analogues as antiproliferatives.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Antineoplastic Agents; Drug Screening

2001
Synergism of the polyamine analogue, N1,N11-bisethylnorspermine with cis-diaminedichloroplatinum (II) against murine neoplastic cell lines in vitro and in vivo.
    Cancer letters, 1996, Jan-19, Volume: 99, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cisplatin; Disease Susceptib

1996
Simultaneous determination of polyamines, N-acetylated polyamines and the polyamine analogues BE-3-3-3 and BE-4-4-4-4 by capillary gas chromatography with nitrogen-phosphorus detection.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Oct-24, Volume: 700, Issue:1-2

    Topics: Acetylation; Animals; Chromatography, Gas; Leukemia L1210; Polyamines; Propylamines; Sensitivity and

1997
Selective labelling of cell-surface polyamine-binding proteins on leukaemic and solid-tumour cell types using a new polyamine photoprobe.
    The Biochemical journal, 1997, Dec-15, Volume: 328 ( Pt 3)

    Topics: Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Cell Membrane; Cross-Linking

1997
Role of the methylene backbone in the antiproliferative activity of polyamine analogues on L1210 cells.
    Cancer research, 1989, Jun-01, Volume: 49, Issue:11

    Topics: Animals; Antineoplastic Agents; Binding, Competitive; Cell Division; Cell Survival; DNA, Neoplasm; L

1989