n(1),n(11)-diethylnorspermine has been researched along with Disease Exacerbation in 1 studies
N(1),N(11)-diethylnorspermine: structure given in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| " Polyamine analogs down-regulate ornithine decarboxylase, induce spermidine/spermine N1-acetyltransferase, deplete natural polyamine pools, inhibit growth, and induce programmed cell death in breast cancer models." | 9.10 | A Phase II study of the polyamine analog N1,N11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer. ( Armstrong, DK; Bender, JF; Carducci, MK; Casero, RA; Davidson, NE; Fetting, JH; Riley, CD; Wolff, AC, 2003) |
| " Polyamine analogs down-regulate ornithine decarboxylase, induce spermidine/spermine N1-acetyltransferase, deplete natural polyamine pools, inhibit growth, and induce programmed cell death in breast cancer models." | 5.10 | A Phase II study of the polyamine analog N1,N11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer. ( Armstrong, DK; Bender, JF; Carducci, MK; Casero, RA; Davidson, NE; Fetting, JH; Riley, CD; Wolff, AC, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wolff, AC | 1 |
| Armstrong, DK | 1 |
| Fetting, JH | 1 |
| Carducci, MK | 1 |
| Riley, CD | 1 |
| Bender, JF | 1 |
| Casero, RA | 1 |
| Davidson, NE | 1 |
1 trial available for n(1),n(11)-diethylnorspermine and Disease Exacerbation
| Article | Year |
|---|---|
A Phase II study of the polyamine analog N1,N11-diethylnorspermine (DENSpm) daily for five days every 21 days in patients with previously treated metastatic breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Disease Progression; Drug Administration Sched | 2003 |