n(1)-methylnicotinamide has been researched along with Parkinson Disease in 3 studies
N(1)-methylnicotinamide: RN given refers to parent cpd
1-methylnicotinamide : A pyridinium ion comprising nicotinamide having a methyl group at the 1-position. It is a metabolite of nicotinamide which was initially considered to be biologically inactive but has emerged as an anti-thrombotic and anti-inflammatory agent.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukushima, T | 3 |
| Tawara, T | 1 |
| Isobe, A | 1 |
| Hojo, N | 1 |
| Shiwaku, K | 1 |
| Yamane, Y | 1 |
| Kaetsu, A | 1 |
| Lim, H | 1 |
| Moriyama, M | 1 |
1 review available for n(1)-methylnicotinamide and Parkinson Disease
| Article | Year |
|---|---|
[Elucidation of paraquat poisoning mechanism and development of the neuronal death model].
Topics: Animals; Chaperonin 60; Disease Models, Animal; Electron Transport Complex I; Herbicides; Humans; Li | 2002 |
2 other studies available for n(1)-methylnicotinamide and Parkinson Disease
| Article | Year |
|---|---|
Radical formation site of cerebral complex I and Parkinson's disease.
Topics: Animals; Brain; Cattle; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Hydroxyl Ra | 1995 |
Possible role of 1-methylnicotinamide in the pathogenesis of Parkinson's disease.
Topics: Animals; Brain; Cell Fractionation; Cytosol; Dopamine; Dose-Response Relationship, Drug; Gas Chromat | 2002 |