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n(1)-methylnicotinamide and Obesity

n(1)-methylnicotinamide has been researched along with Obesity in 5 studies

N(1)-methylnicotinamide: RN given refers to parent cpd
1-methylnicotinamide : A pyridinium ion comprising nicotinamide having a methyl group at the 1-position. It is a metabolite of nicotinamide which was initially considered to be biologically inactive but has emerged as an anti-thrombotic and anti-inflammatory agent.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"Patients with manifest type 2 diabetes have a significantly (approximately twofold) higher NNMT expression both in omental and subcutaneous WAT compared with controls."2.80Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance. ( Blüher, M; Dietrich, A; Kannt, A; Klöting, N; Pfenninger, A; Schön, MR; Teichert, L; Tönjes, A, 2015)
"Obesity is a major health problem, and although caloric restriction and exercise are successful strategies to lose adipose tissue in obese individuals, a simultaneous decrease in skeletal muscle mass, negatively effects metabolism and muscle function."1.48N ( Ahlqvist, E; Almgren, P; Calbet, JAL; de Pablos-Velasco, P; Edlund, A; Ekman, C; Ekström, O; Eliasson, L; Fernandez, C; Groop, L; Hansson, O; Hjort, L; Holmberg, HC; Jörgensen, SW; Martin-Rincon, M; Mattiasson, M; Morales-Alamo, D; Oskolkov, N; Ottosson, F; Pérez-López, A; Perez-Suarez, I; Stenkula, KG; Ström, K; Vaag, A; Wierup, N; Zhou, Y, 2018)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Zhang, J1
Chen, Y1
Liu, C1
Li, L2
Li, P1
Ström, K1
Morales-Alamo, D1
Ottosson, F1
Edlund, A1
Hjort, L1
Jörgensen, SW1
Almgren, P1
Zhou, Y1
Martin-Rincon, M1
Ekman, C1
Pérez-López, A1
Ekström, O1
Perez-Suarez, I1
Mattiasson, M1
de Pablos-Velasco, P1
Oskolkov, N1
Ahlqvist, E1
Wierup, N1
Eliasson, L1
Vaag, A1
Groop, L1
Stenkula, KG1
Fernandez, C1
Calbet, JAL1
Holmberg, HC1
Hansson, O1
Kannt, A1
Pfenninger, A1
Teichert, L1
Tönjes, A1
Dietrich, A1
Schön, MR1
Klöting, N1
Blüher, M1
Liu, M2
Chu, J2
Zhu, B1
Zhang, Q1
Yin, X1
Jiang, W1
Dai, G1
Ju, W2
Wang, Z2
Yang, Q1
Fang, Z1
Gu, Y1
Shi, H1
Zhang, R1
Wang, L1
Chen, J1
Shen, L1
Yu, P1
Chen, X1

Trials

1 trial available for n(1)-methylnicotinamide and Obesity

ArticleYear
Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance.
    Diabetologia, 2015, Volume: 58, Issue:4

    Topics: Adult; Aged; Bariatric Surgery; Biomarkers; Case-Control Studies; Cross-Sectional Studies; Diabetes

2015

Other Studies

4 other studies available for n(1)-methylnicotinamide and Obesity

ArticleYear
N
    Journal of diabetes research, 2020, Volume: 2020

    Topics: Acetylation; Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Type 2; Forkhead Box Protein O1;

2020
N
    Scientific reports, 2018, 02-14, Volume: 8, Issue:1

    Topics: Adult; Body Mass Index; Caloric Restriction; Cells, Cultured; Energy Metabolism; Exercise; Exercise

2018
Serum N(1)-Methylnicotinamide Is Associated With Obesity and Diabetes in Chinese.
    The Journal of clinical endocrinology and metabolism, 2015, Volume: 100, Issue:8

    Topics: Adult; Asian People; Body Mass Index; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Fem

2015
Serum N1-Methylnicotinamide is Associated With Coronary Artery Disease in Chinese Patients.
    Journal of the American Heart Association, 2017, 02-07, Volume: 6, Issue:2

    Topics: Aged; Biomarkers; Body Mass Index; China; Chromatography, Liquid; Comorbidity; Coronary Angiography;

2017