n(1)-methylnicotinamide has been researched along with Neoplasms in 2 studies
N(1)-methylnicotinamide: RN given refers to parent cpd
1-methylnicotinamide : A pyridinium ion comprising nicotinamide having a methyl group at the 1-position. It is a metabolite of nicotinamide which was initially considered to be biologically inactive but has emerged as an anti-thrombotic and anti-inflammatory agent.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As a result, NNMT-expressing cancer cells have an altered epigenetic state that includes hypomethylated histones and other cancer-related proteins combined with heightened expression of protumorigenic gene products." | 1.39 | NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink. ( Cravatt, BF; Ulanovskaya, OA; Zuhl, AM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, Y | 1 |
| Martin, NI | 1 |
| van Haren, MJ | 1 |
| Ulanovskaya, OA | 1 |
| Zuhl, AM | 1 |
| Cravatt, BF | 1 |
1 review available for n(1)-methylnicotinamide and Neoplasms
| Article | Year |
|---|---|
Nicotinamide N-methyl transferase (NNMT): An emerging therapeutic target.
Topics: Enzyme Inhibitors; Humans; Metabolic Diseases; Neoplasms; Neurodegenerative Diseases; Niacinamide; N | 2021 |
1 other study available for n(1)-methylnicotinamide and Neoplasms
| Article | Year |
|---|---|
NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink.
Topics: Epigenesis, Genetic; Humans; Methionine; Methylation; Models, Genetic; Neoplasms; Niacinamide; Nicot | 2013 |